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Morphological and molecular characterization of Chloromyxum dasyatidis n. sp. (Myxosporea: Chloromyxidae) in the common stingray Dasyatis pastinaca (Linnaeus) from Tunisian waters (Central Mediterranean Sea)
Syst Parasitol. 2023 Sep 9. doi: 10.1007/s11230-023-10111-6. Online ahead of print.ABSTRACTA new species of Chloromyxum Mingazzini, 1890, C. dasyatidis n. sp., is described from the gallbladder of the elasmobranch fish Dasyatis pastinaca (Linnaeus) from the Mediterranean coast off Tunisia. Mature myxospores were subspherical measuring 13.0 ± 0.3 (12.5-13.9) µm in length, 11.3 ± 0.5 (10.2-12.2) µm in width, and 11.8 ± 0.5 (11.4-12.7) µm in thickness. Four pyriform polar capsules 4.4 ± 0.3 (4.0-4.9) µm long and 3.5 ± 0.3 (3.0-3.8) µm wide. Valves were ornamented by 5 to 7 elevated surface ridges and displayed short...
Source: Systematic Parasitology - September 9, 2023 Category: Parasitology Authors: Luis F Rangel Amira Elloumi Yann Quilichini Maria J Santos Sihem Bahri Source Type: research

The effects of P-glycoprotein induction on ivermectin-induced behavioural alterations in zebrafish (Danio rerio) under varying diets
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Sep 7:109740. doi: 10.1016/j.cbpc.2023.109740. Online ahead of print.ABSTRACTThe neuroprotective effects of inducing the blood-brain barrier ATP-binding cassette protein transporter P-glycoprotein (P-gp) with clotrimazole (CTZ) in both fed and fasted zebrafish (Danio rerio) against the CNS-toxicant ivermectin (IVM, 22,23-dihydro avermectin B1a + 22,23-dihydro avermectin B1b) were examined. Zebrafish were administered 2 μmol/kg IVM intraperitoneally, and various behavioural assays (swimming performance, exploratory behaviour, olfactory responses, motor coordination, and escape...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 9, 2023 Category: Biochemistry Authors: Vinicius Cavicchioli Azevedo Christopher J Kennedy Source Type: research

Morphological and molecular characterization of Chloromyxum dasyatidis n. sp. (Myxosporea: Chloromyxidae) in the common stingray Dasyatis pastinaca (Linnaeus) from Tunisian waters (Central Mediterranean Sea)
Syst Parasitol. 2023 Sep 9. doi: 10.1007/s11230-023-10111-6. Online ahead of print.ABSTRACTA new species of Chloromyxum Mingazzini, 1890, C. dasyatidis n. sp., is described from the gallbladder of the elasmobranch fish Dasyatis pastinaca (Linnaeus) from the Mediterranean coast off Tunisia. Mature myxospores were subspherical measuring 13.0 ± 0.3 (12.5-13.9) µm in length, 11.3 ± 0.5 (10.2-12.2) µm in width, and 11.8 ± 0.5 (11.4-12.7) µm in thickness. Four pyriform polar capsules 4.4 ± 0.3 (4.0-4.9) µm long and 3.5 ± 0.3 (3.0-3.8) µm wide. Valves were ornamented by 5 to 7 elevated surface ridges and displayed short...
Source: Systematic Parasitology - September 9, 2023 Category: Parasitology Authors: Luis F Rangel Amira Elloumi Yann Quilichini Maria J Santos Sihem Bahri Source Type: research

Health impact assessment after Danio rerio long-term exposure to environmentally relevant concentrations of metformin and guanylurea
Chemosphere. 2023 Sep 7:140070. doi: 10.1016/j.chemosphere.2023.140070. Online ahead of print.ABSTRACTThe antidiabetic drug metformin (MET) and its metabolite guanylurea (GUA) have been frequently and ubiquitously detected in surface water. Consequently, there has been a consistent rise in studying the toxicity of MET and GUA in fish over the past decade. Nonetheless, it is noteworthy that no study has assessed the harmful effects both compounds might trigger on fish blood and organs after chronic exposure. Taking into consideration the data above, our research strived to accomplish two primary objectives: Firstly, to asse...
Source: Chemosphere - September 9, 2023 Category: Chemistry Authors: Gustavo Axel Elizalde-Vel ázquez Selene Elizabeth Herrera-V ázquez Leobardo Manuel G ómez-Oliván Sandra Garc ía-Medina Source Type: research

Morphological and molecular characterization of Chloromyxum dasyatidis n. sp. (Myxosporea: Chloromyxidae) in the common stingray Dasyatis pastinaca (Linnaeus) from Tunisian waters (Central Mediterranean Sea)
Syst Parasitol. 2023 Sep 9. doi: 10.1007/s11230-023-10111-6. Online ahead of print.ABSTRACTA new species of Chloromyxum Mingazzini, 1890, C. dasyatidis n. sp., is described from the gallbladder of the elasmobranch fish Dasyatis pastinaca (Linnaeus) from the Mediterranean coast off Tunisia. Mature myxospores were subspherical measuring 13.0 ± 0.3 (12.5-13.9) µm in length, 11.3 ± 0.5 (10.2-12.2) µm in width, and 11.8 ± 0.5 (11.4-12.7) µm in thickness. Four pyriform polar capsules 4.4 ± 0.3 (4.0-4.9) µm long and 3.5 ± 0.3 (3.0-3.8) µm wide. Valves were ornamented by 5 to 7 elevated surface ridges and displayed short...
Source: Systematic Parasitology - September 9, 2023 Category: Parasitology Authors: Luis F Rangel Amira Elloumi Yann Quilichini Maria J Santos Sihem Bahri Source Type: research

The effects of P-glycoprotein induction on ivermectin-induced behavioural alterations in zebrafish (Danio rerio) under varying diets
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Sep 7:109740. doi: 10.1016/j.cbpc.2023.109740. Online ahead of print.ABSTRACTThe neuroprotective effects of inducing the blood-brain barrier ATP-binding cassette protein transporter P-glycoprotein (P-gp) with clotrimazole (CTZ) in both fed and fasted zebrafish (Danio rerio) against the CNS-toxicant ivermectin (IVM, 22,23-dihydro avermectin B1a + 22,23-dihydro avermectin B1b) were examined. Zebrafish were administered 2 μmol/kg IVM intraperitoneally, and various behavioural assays (swimming performance, exploratory behaviour, olfactory responses, motor coordination, and escape...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 9, 2023 Category: Biochemistry Authors: Vinicius Cavicchioli Azevedo Christopher J Kennedy Source Type: research

Health impact assessment after Danio rerio long-term exposure to environmentally relevant concentrations of metformin and guanylurea
Chemosphere. 2023 Sep 7:140070. doi: 10.1016/j.chemosphere.2023.140070. Online ahead of print.ABSTRACTThe antidiabetic drug metformin (MET) and its metabolite guanylurea (GUA) have been frequently and ubiquitously detected in surface water. Consequently, there has been a consistent rise in studying the toxicity of MET and GUA in fish over the past decade. Nonetheless, it is noteworthy that no study has assessed the harmful effects both compounds might trigger on fish blood and organs after chronic exposure. Taking into consideration the data above, our research strived to accomplish two primary objectives: Firstly, to asse...
Source: Chemosphere - September 9, 2023 Category: Chemistry Authors: Gustavo Axel Elizalde-Vel ázquez Selene Elizabeth Herrera-V ázquez Leobardo Manuel G ómez-Oliván Sandra Garc ía-Medina Source Type: research

The effects of P-glycoprotein induction on ivermectin-induced behavioural alterations in zebrafish (Danio rerio) under varying diets
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Sep 7:109740. doi: 10.1016/j.cbpc.2023.109740. Online ahead of print.ABSTRACTThe neuroprotective effects of inducing the blood-brain barrier ATP-binding cassette protein transporter P-glycoprotein (P-gp) with clotrimazole (CTZ) in both fed and fasted zebrafish (Danio rerio) against the CNS-toxicant ivermectin (IVM, 22,23-dihydro avermectin B1a + 22,23-dihydro avermectin B1b) were examined. Zebrafish were administered 2 μmol/kg IVM intraperitoneally, and various behavioural assays (swimming performance, exploratory behaviour, olfactory responses, motor coordination, and escape...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 9, 2023 Category: Biochemistry Authors: Vinicius Cavicchioli Azevedo Christopher J Kennedy Source Type: research

Morphological and molecular characterization of Chloromyxum dasyatidis n. sp. (Myxosporea: Chloromyxidae) in the common stingray Dasyatis pastinaca (Linnaeus) from Tunisian waters (Central Mediterranean Sea)
Syst Parasitol. 2023 Sep 9. doi: 10.1007/s11230-023-10111-6. Online ahead of print.ABSTRACTA new species of Chloromyxum Mingazzini, 1890, C. dasyatidis n. sp., is described from the gallbladder of the elasmobranch fish Dasyatis pastinaca (Linnaeus) from the Mediterranean coast off Tunisia. Mature myxospores were subspherical measuring 13.0 ± 0.3 (12.5-13.9) µm in length, 11.3 ± 0.5 (10.2-12.2) µm in width, and 11.8 ± 0.5 (11.4-12.7) µm in thickness. Four pyriform polar capsules 4.4 ± 0.3 (4.0-4.9) µm long and 3.5 ± 0.3 (3.0-3.8) µm wide. Valves were ornamented by 5 to 7 elevated surface ridges and displayed short...
Source: Systematic Parasitology - September 9, 2023 Category: Parasitology Authors: Luis F Rangel Amira Elloumi Yann Quilichini Maria J Santos Sihem Bahri Source Type: research

Health impact assessment after Danio rerio long-term exposure to environmentally relevant concentrations of metformin and guanylurea
Chemosphere. 2023 Sep 7:140070. doi: 10.1016/j.chemosphere.2023.140070. Online ahead of print.ABSTRACTThe antidiabetic drug metformin (MET) and its metabolite guanylurea (GUA) have been frequently and ubiquitously detected in surface water. Consequently, there has been a consistent rise in studying the toxicity of MET and GUA in fish over the past decade. Nonetheless, it is noteworthy that no study has assessed the harmful effects both compounds might trigger on fish blood and organs after chronic exposure. Taking into consideration the data above, our research strived to accomplish two primary objectives: Firstly, to asse...
Source: Chemosphere - September 9, 2023 Category: Chemistry Authors: Gustavo Axel Elizalde-Vel ázquez Selene Elizabeth Herrera-V ázquez Leobardo Manuel G ómez-Oliván Sandra Garc ía-Medina Source Type: research

The effects of P-glycoprotein induction on ivermectin-induced behavioural alterations in zebrafish (Danio rerio) under varying diets
Comp Biochem Physiol C Toxicol Pharmacol. 2023 Sep 7:109740. doi: 10.1016/j.cbpc.2023.109740. Online ahead of print.ABSTRACTThe neuroprotective effects of inducing the blood-brain barrier ATP-binding cassette protein transporter P-glycoprotein (P-gp) with clotrimazole (CTZ) in both fed and fasted zebrafish (Danio rerio) against the CNS-toxicant ivermectin (IVM, 22,23-dihydro avermectin B1a + 22,23-dihydro avermectin B1b) were examined. Zebrafish were administered 2 μmol/kg IVM intraperitoneally, and various behavioural assays (swimming performance, exploratory behaviour, olfactory responses, motor coordination, and escape...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - September 9, 2023 Category: Biochemistry Authors: Vinicius Cavicchioli Azevedo Christopher J Kennedy Source Type: research

Health impact assessment after Danio rerio long-term exposure to environmentally relevant concentrations of metformin and guanylurea
Chemosphere. 2023 Sep 7:140070. doi: 10.1016/j.chemosphere.2023.140070. Online ahead of print.ABSTRACTThe antidiabetic drug metformin (MET) and its metabolite guanylurea (GUA) have been frequently and ubiquitously detected in surface water. Consequently, there has been a consistent rise in studying the toxicity of MET and GUA in fish over the past decade. Nonetheless, it is noteworthy that no study has assessed the harmful effects both compounds might trigger on fish blood and organs after chronic exposure. Taking into consideration the data above, our research strived to accomplish two primary objectives: Firstly, to asse...
Source: Chemosphere - September 9, 2023 Category: Chemistry Authors: Gustavo Axel Elizalde-Vel ázquez Selene Elizabeth Herrera-V ázquez Leobardo Manuel G ómez-Oliván Sandra Garc ía-Medina Source Type: research