Pickering emulsions with high ionic strength resistance stabilized by pea protein isolate-polyglycerol conjugate particles with good biocompatibility
Int J Biol Macromol. 2024 Apr 23:131797. doi: 10.1016/j.ijbiomac.2024.131797. Online ahead of print.ABSTRACTAmong various biopolymers, protein particles are widely used for stabilizing Pickering emulsions, yet their emulsifying ability are easily influenced by the ion concentration, pH, and high temperatures. To address these challenges, this study utilized chemical modification to prepare pea protein isolate-polyglycerol (PPI-PG) conjugates by Schiff-base reaction. Compared with other chemical modifications, this method produces conjugate particles with excellent biocompatibility, capable of promoting cell proliferation b...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Yijie Wang Yunpeng Xie Ting Li Yang Wang Jie Jiang Xuhui Zhang Bihua Xia Shibo Wang Jing Huang Weifu Dong Source Type: research

Premise setting for sustainable developing adsorption in environmental remediation using graphitic carbon nitride@agar-derived porous carbon composite
Int J Biol Macromol. 2024 Apr 23:131760. doi: 10.1016/j.ijbiomac.2024.131760. Online ahead of print.ABSTRACTIn the adsorption process for wastewater treatment, the adsorbent plays an important role. A composite adsorptive material composed of graphitic carbon nitride and agar-derived porous carbon (CNPC) was fabricated from simple precursors (melamine, thiourea, and agar) and through a facile procedure with different melamine and thiourea ratios. Characterization of CNPC proved a successful formation of a porous structure consisting of mesopores and macropores, wherein CNPC holds distinctive electrochemical (lowered resist...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Nguyen Huu Hieu Hoang An Nguyen Hung Vu Le Phuoc Tai Nguyen Minh Dat Ngo Khanh Duc Nguyen Duy Hai Nguyen Thanh Hoai Nam Le Minh Huong Che Quang Cong Le Tan Tai Source Type: research

The ameliorative effect on chemotherapy-induced injury and tumor immunosuppressive microenvironment of the polysaccharide from the rhizome of Menispermum dauricum DC
This study laid the foundation for the development of MDP as a polysaccharide drug for the treatment or adjuvant therapy of tumors and has important significance for the further clinical application of polysaccharides.PMID:38663694 | DOI:10.1016/j.ijbiomac.2024.131828 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Pei Yang Yang Zhai Qian Liu Guiyun Cao Yan Ma Jiangying Cao Lihao Zhu Yuhong Liu Source Type: research

Dimensionally stable and durable wood by lignin impregnation
Int J Biol Macromol. 2024 Apr 23:131684. doi: 10.1016/j.ijbiomac.2024.131684. Online ahead of print.ABSTRACTCracking, warping, and decaying stemming from wood's poor dimensional stability and durability are the most annoying issues of natural wood. There is an urgent need to address these issues, of which, sustainable and green chemical treatments are favorably welcomed. Herein, we developed a facile method through the incorporation of environmentally friendly biopolymer lignin into wood cells for wood dimensional stability and durability enhancement. Enzymatic hydrolysis lignin (EHL) was dissolved into various solvents fo...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Weiqi Leng Jing Wang Sheng He Xiang Wang Shengcheng Zhai Wanzhao Li Haiyang Quan Buyun Lu Jiangtao Shi Islam Hafez Xuefeng Zhang Source Type: research

Effect of emulsified lipid and saponified lipid on the enzyme desizing of starch and its mechanism
Int J Biol Macromol. 2024 Apr 23:131835. doi: 10.1016/j.ijbiomac.2024.131835. Online ahead of print.ABSTRACTTo enhance the flexibility of starch film adhesion on yarns, sizing lipids (saponified lipid or emulsified lipid) must be added during the sizing process. However, different types of sizing lipids may have diverse combinations with starch to impact enzyme desizing. Therefore, this study investigated the effects of saponified lipid and emulsified lipid commonly used in warp sizing on the hydrolysis of starch. Additionally, the desizing efficiency and chain structure of desizing residues were analyzed. Experimental res...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Xun Zhang Xuerong Fan Wei Li Source Type: research

Tandemly expanded OR17b in Himalaya ghost moth facilitates larval food allocation via olfactory reception of plant-derived tricosane
Int J Biol Macromol. 2024 Apr 23:131503. doi: 10.1016/j.ijbiomac.2024.131503. Online ahead of print.ABSTRACTHerbivorous insects utilize intricate olfactory mechanisms to locate food plants. The chemical communication of insect-plant in primitive lineage offers insights into evolutionary milestones of divergent olfactory modalities. Here, we focus on a system endemic to the Qinghai-Tibetan Plateau to unravel the chemical and molecular basis of food preference in ancestral Lepidoptera. We conducted volatile profiling, neural electrophysiology, and chemotaxis assays with a panel of host plant organs to identify attractants fo...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Rui Tang Hao Guo Jia-Qi Chen Cong Huang Xiang-Xin Kong Li Cao Fang-Hao Wan Ri-Chou Han Source Type: research

Effect of dynamic high-pressure treatments on the multi-level structure of starch macromolecule and their techno-functional properties: A review
Int J Biol Macromol. 2024 Apr 23:131830. doi: 10.1016/j.ijbiomac.2024.131830. Online ahead of print.ABSTRACTOver the past decades, dynamic high-pressure treatment (DHPT) executed by high-pressure homogenization (HPH) or microfluidization (DHPM) technology has received humongous research attention for starch macromolecule modification. However, the studies on starch multi-level structure alterations by DHPT have received inadequate attention. Furthermore, no review comprehensively covers all aspects of DHPT, explicitly addressing the combined effects of both technologies (HPH or DHPM) on starch's structural and functional c...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: None Sahil Mitali Madhumita Pramod K Prabhakar Source Type: research

ARF6 promotes Streptococcus suis suilysin induced apoptosis in HBMECs
In this study, we identified the interacting proteins between SLY and human brain microvascular endothelial cells (HBMECs) using the TurboID-mediated proximity labeling method. 251 unique proteins were identified in TurboID-SLY treated group, of which six plasma membrane proteins including ARF6, GRK6, EPB41L5, DSC1, TJP2, and PNN were identified. We found that the proteins capable of interacting with SLY are ARF6 and PNN. Subsequent investigations revealed that ARF6 substantially increased the invasive ability of S. suis in HBMECs. Furthermore, ARF6 promoted SLY-induced the activation of p38 MAPK signaling pathway in HBMEC...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Changsheng Jiang Pei Zhou Xiaoqian Zhang NingNing Ma Yaofang Hu Mengjia Zhang Ahmed H Ghonaim Huimin Li Ling Dong Wei Zeng Chang Li Yifei Lang Yumei Sun Qigai He Wentao Li Source Type: research

Characterization of multilayer bacterial cellulose-chitosan films loaded with grape bagasse antioxidant extract: Insights into spectral and water properties, microstructure, and antioxidant activity
Int J Biol Macromol. 2024 Apr 23:131774. doi: 10.1016/j.ijbiomac.2024.131774. Online ahead of print.ABSTRACTThis work explores the development and characterization of composite multilayer films comprising bacterial cellulose (BC) and chitosan enriched with antioxidant compounds from grape bagasse extract (GE) and glycerol. SEM images revealed a compact structure with successful interactions between BC and chitosan, confirmed by FT-IR analysis. Equilibrium moisture content, water vapor permeability (WVP), swollen capacity, and solubility were systematically investigated, unveiling the influence of glycerol and GE concentrat...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Patricia Caz ón Gema Puertas Manuel V ázquez Source Type: research

Endogenous reactive oxygen species (ROS)-driven protein oxidation regulates emulsifying and foaming properties of liquid egg white
In conclusion, ROS acted as the predominant factor causing deterioration of liquid EW, triggering moderate oxidation that enhanced the superior foaming and emulsifying properties of EWP, and excessive oxidation diminished the functional characteristics by affecting the molecular structure.PMID:38663701 | DOI:10.1016/j.ijbiomac.2024.131843 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Jiayi Li Ziyuan Wang Nan Xiao Shanguang Guo Minmin Ai Source Type: research

Effect of zein-pectin composite particles on the stability and rheological properties of gelatin/hydroxypropyl methylcellulose water-water systems
This study may serve as a reference for advancing the processability of HPMC.PMID:38663702 | DOI:10.1016/j.ijbiomac.2024.131846 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Xinnan Hu Chengkai Zhu Zhonghe Hu Wangyang Shen Zhili Ji Fang Li Cheng Guo Source Type: research

NhaA: A promising adjuvant target for colistin against resistant Escherichia coli
Int J Biol Macromol. 2024 Apr 23:131833. doi: 10.1016/j.ijbiomac.2024.131833. Online ahead of print.ABSTRACTThe emergence and widespread of multidrug-resistant Gram-negative bacteria have posed a severe threat to human health and environmental safety, escalating into a global medical crisis. Utilization of antibiotic adjuvants is a rapid approach to combat bacterial resistance effectively since the development of new antimicrobial agents is a formidable challenge. NhaA, driven by proton motive force, is a crucial secondary transporter on the cytoplasmic membrane of Escherichia coli. We found that 2-Aminoperimidine (2-AP), ...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Xuelin Wang Yong Cui Zhaohui Wang Huilin Jiang Lei Ma Wenwen Li Xinyi Yang Jinghai Zhang Yongshan Zhao Guoqing Li Source Type: research

Development and evaluation of a pH-responsive Mimosa pudica seed mucilage/ β- cyclodextrin-co-poly(methacrylate) hydrogel for controlled drug delivery: In vitro and in vivo assessment
Int J Biol Macromol. 2024 Apr 23:131832. doi: 10.1016/j.ijbiomac.2024.131832. Online ahead of print.ABSTRACTIn this comprehensive investigation, a novel pH-responsive hydrogel system comprising mimosa seed mucilage (MSM), β-cyclodextrin (β-CD), and methacrylic acid (MAA) was developed via free radical polymerization technique to promote controlled drug delivery. The hydrogel synthesis involved strategic variations in polymer, monomer, and crosslinker content in fine-tuning its drug-release properties. The resultant hydrogel exhibited remarkable pH sensitivity, selectively liberating the model drug (Capecitabine = CAP) un...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Tahira Yasmin Asif Mahmood Muhammad Farooq Rai Muhammad Sarfraz Abir Boublia Umaira Rehman Muhammad Umar Ashraf Javed Khan Bhutto Barbara Ernst Malik Albrahim Noureddine Elboughdiri Krishna Kumar Yadav Maha Awjan Alreshidi Hira Ijaz Yacine Benguerba Source Type: research

The structures of two polysaccharides from Lepidium meyenii and their immunomodulatory effects via activating NF- κB signaling pathway
Int J Biol Macromol. 2024 Apr 23:131761. doi: 10.1016/j.ijbiomac.2024.131761. Online ahead of print.ABSTRACTLepidium meyenii Walp., also known as the "Peruvian national treasure", is a popular functional food in the daily lives of Peruvian people due to its bioactive with main polysaccharides. However, studies on polysaccharides isolated from Lepidium meyenii were few. Two new highly heterogeneous polysaccharides, MCP-1a and MCP-2b, were isolated and purified from the tuber of Lepidium meyenii. The structure characterization revealed that MCP-1a primarily consisted of D-Glc and had a molecular weight of 6.6 kDa. Its backbo...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: Zhou-Wei Wu Xing-Rong Peng Xiao-Cui Liu Luan Wen Xin-Yu Tao Abdulbaset Al-Romaima Ming-Yi Wu Ming-Hua Qiu Source Type: research

In-vitro and in silco analysis and antitumor studies of novel Cu(II) and V(V) complexes of N-p-Tolylbenzohydroxamic acid
Int J Biol Macromol. 2024 Apr 23:131768. doi: 10.1016/j.ijbiomac.2024.131768. Online ahead of print.ABSTRACTCopper(L2Cu) and vanadium(L2VOCl) complexes of N-p-tolylbenzohydroxamic acid (LH) ligand have been investigated for DNA binding efficacy by multiple analytical, spectral, and computational techniques. The results revealed that complexes as groove binders as evidenced by UV absorption. Fluorescence studies including displacement assay using classical intercalator ethidium bromide as fluorescent probe also confirmed as groove binders. The viscometric analysis too supports the inferences as strong groove binders for bot...
Source: International Journal of Biological Macromolecules - April 25, 2024 Category: Biochemistry Authors: M Tripathi Y Thakur R Syed A K Asatkar M S Al Qahtani D Das R Agrawal B Verma R Pande Source Type: research