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Nutrition: Calcium

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Total 38427 results found since Jan 2013.

Serum calcium concentrations are inversely correlated with pancreatic lipase concentrations in dogs
Am J Vet Res. 2023 Sep 19:1-5. doi: 10.2460/ajvr.23.07.0160. Online ahead of print.ABSTRACTOBJECTIVE: (1) Determine if a relationship exists between ionized calcium (iCa) and pancreatic lipase (cPLI) concentration in dogs, and (2) assess for correlation between resolving hypercalcemia and cPLI concentrations in dogs after treatment for primary hyperparathyroidism (PHPT).SAMPLES: Phase I, 44 residual serum samples (collected April 2023) from client-owned dogs with a clinical indication for cPLI quantification. Phase II, 24 residual serum samples (collected August 2022 through February 2023) from client-owned dogs with PHPT ...
Source: American Journal of Veterinary Research - September 15, 2023 Category: Veterinary Research Authors: Harry Cridge Sichao Wang Joerg M Steiner Source Type: research

Exosomes and their miRNA/protein profile in keratoconus-derived corneal stromal cells
Exp Eye Res. 2023 Sep 13:109642. doi: 10.1016/j.exer.2023.109642. Online ahead of print.ABSTRACTKeratoconus (KC) is a corneal thinning disorder and a leading cause of corneal transplantation worldwide. Exosomes are small, secreted extracellular vesicles (30-150 nm) that mediate cellular communication via their proteins, lipids, and nucleic acid content. We aimed to characterize the exosomes secreted by primary corneal fibroblasts from subjects with or without KC. Using human keratoconus stromal fibroblast cells (HKC, n = 4) and healthy stromal fibroblasts (HCF, n = 4), we collected and isolated exosomes using serial ultrac...
Source: Experimental Eye Research - September 15, 2023 Category: Opthalmology Authors: Rachel Hadvina Mariam Lotfy Khaled Theresa Akoto Wenbo Zhi Dimitrios Karamichos Yutao Liu Source Type: research

Pantoprazole-Induced Bone Loss through Gastrin Secretion: A Stereological Study
CONCLUSION: Overall findings revealed that pantoprazole caused bone loss, which could be prevented by adding octreotide. Because these detrimental effects were not detected in rats given both Oct and Pan, it was suggested that the effect of Pan on bone was produced by a hypergastrinemic condition.PMID:37711876 | PMC:PMC10499535 | DOI:10.1155/2023/2594664
Source: Biomed Res - September 15, 2023 Category: Research Authors: Forough Saki Mesbah Shams Sanaz Dastghaib Farhad Koohpeyma Source Type: research

Human PLCG2 Haploinsufficiency Results in a Novel NK Cell Immunodeficiency
CONCLUSIONS: PLCG2 haploinsufficiency represents a distinct syndrome from previous variants characterized by NK cell immunodeficiency with herpes virus susceptibility, expanding the spectrum of PLCG2-related disease.PMID:37714437 | DOI:10.1016/j.jaci.2023.09.002
Source: Herpes - September 15, 2023 Category: Infectious Diseases Authors: Joshua B Alinger Emily M Mace Justin R Porter Annelise Y Mah-Som Allyssa L Daugherty Stephanie Li Allison A Throm Jeanette T Pingel Nermina Saucier Albert Yao Ivan K Chinn James R Lupski Mohammad Ehlayel Michael Keller Greg R Bowman Megan A Cooper Jordan Source Type: research

Calcium signals and potential therapy targets in ovarian cancer (Review)
Int J Oncol. 2023 Nov;63(5):125. doi: 10.3892/ijo.2023.5573. Epub 2023 Sep 15.ABSTRACTOvarian cancer (OC) is a deadly disease. The poor prognosis and high lethality of OC are attributed to its high degrees of aggressiveness, resistance to chemotherapy and recurrence rates. Calcium ion (Ca2+) signaling has received attention in recent years, as it appears to form an essential part of various aspects of cancer pathophysiology and is a potential therapeutic target for OC treatment. Disruption of normal Ca2+ signaling pathways can induce changes in cell cycle progression, apoptosis, proliferation and migration and invasion, le...
Source: International Journal of Oncology - September 15, 2023 Category: Cancer & Oncology Authors: Fengying Deng Mengyu Fu Chenxuan Zhao Jiahui Lei Ting Xu Bingyu Ji Hongmei Ding Yueming Zhang Jie Chen Junlan Qiu Qinqin Gao Source Type: research

Serum calcium concentrations are inversely correlated with pancreatic lipase concentrations in dogs
Am J Vet Res. 2023 Sep 19:1-5. doi: 10.2460/ajvr.23.07.0160. Online ahead of print.ABSTRACTOBJECTIVE: (1) Determine if a relationship exists between ionized calcium (iCa) and pancreatic lipase (cPLI) concentration in dogs, and (2) assess for correlation between resolving hypercalcemia and cPLI concentrations in dogs after treatment for primary hyperparathyroidism (PHPT).SAMPLES: Phase I, 44 residual serum samples (collected April 2023) from client-owned dogs with a clinical indication for cPLI quantification. Phase II, 24 residual serum samples (collected August 2022 through February 2023) from client-owned dogs with PHPT ...
Source: American Journal of Veterinary Research - September 15, 2023 Category: Veterinary Research Authors: Harry Cridge Sichao Wang Joerg M Steiner Source Type: research

MiR-301a-5p modulates parathyroid hormone secretion in secondary hyperparathyroidism possibly by regulating calcium-sensing receptor
CONCLUSION: MiR-301a-5p affects PTH secretion in SHPT possibly by regulating the expression of CaSR.PMID:37712273 | PMC:PMC10505570 | DOI:10.12122/j.issn.1673-4254.2023.08.13
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Liu L Qian P Li J Li S Huang W Yi S Liu W Wu Source Type: research

Serum calcium concentrations are inversely correlated with pancreatic lipase concentrations in dogs
Am J Vet Res. 2023 Sep 19:1-5. doi: 10.2460/ajvr.23.07.0160. Online ahead of print.ABSTRACTOBJECTIVE: (1) Determine if a relationship exists between ionized calcium (iCa) and pancreatic lipase (cPLI) concentration in dogs, and (2) assess for correlation between resolving hypercalcemia and cPLI concentrations in dogs after treatment for primary hyperparathyroidism (PHPT).SAMPLES: Phase I, 44 residual serum samples (collected April 2023) from client-owned dogs with a clinical indication for cPLI quantification. Phase II, 24 residual serum samples (collected August 2022 through February 2023) from client-owned dogs with PHPT ...
Source: American Journal of Veterinary Research - September 15, 2023 Category: Veterinary Research Authors: Harry Cridge Sichao Wang Joerg M Steiner Source Type: research

Antagonism of a key peptide 'T14' driving neurodegeneration: Evaluation of a next generation therapeutic
Biomed Pharmacother. 2023 Sep 13;167:115498. doi: 10.1016/j.biopha.2023.115498. Online ahead of print.ABSTRACTT14, a 14mer peptide derived from the C-terminus of acetylcholinesterase (AChE) is a signalling molecule that could drive neurodegeneration via the alpha 7 nicotinic acetylcholine receptor. Its levels increase as Alzheimer's pathology progresses; however, a cyclic variant of the compound, NBP14, can block the effects of the endogenous linear counterpart in-vitro, ex vivo, and in vivo. Here, we explore the antagonistic potential of two 6mer peptides, NBP6A and NBP6B. These are smaller linear versions of NBP14, desig...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Sanskar Ranglani Sibah Hasan Kashif Mahfooz Jack Gordon Sara Garcia-Rates Susan Greenfield Source Type: research

Calcium signals and potential therapy targets in ovarian cancer (Review)
Int J Oncol. 2023 Nov;63(5):125. doi: 10.3892/ijo.2023.5573. Epub 2023 Sep 15.ABSTRACTOvarian cancer (OC) is a deadly disease. The poor prognosis and high lethality of OC are attributed to its high degrees of aggressiveness, resistance to chemotherapy and recurrence rates. Calcium ion (Ca2+) signaling has received attention in recent years, as it appears to form an essential part of various aspects of cancer pathophysiology and is a potential therapeutic target for OC treatment. Disruption of normal Ca2+ signaling pathways can induce changes in cell cycle progression, apoptosis, proliferation and migration and invasion, le...
Source: International Journal of Oncology - September 15, 2023 Category: Cancer & Oncology Authors: Fengying Deng Mengyu Fu Chenxuan Zhao Jiahui Lei Ting Xu Bingyu Ji Hongmei Ding Yueming Zhang Jie Chen Junlan Qiu Qinqin Gao Source Type: research

MiR-301a-5p modulates parathyroid hormone secretion in secondary hyperparathyroidism possibly by regulating calcium-sensing receptor
CONCLUSION: MiR-301a-5p affects PTH secretion in SHPT possibly by regulating the expression of CaSR.PMID:37712273 | PMC:PMC10505570 | DOI:10.12122/j.issn.1673-4254.2023.08.13
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Liu L Qian P Li J Li S Huang W Yi S Liu W Wu Source Type: research

Safety profile of nirmatrelvir-ritonavir: Evidence of adverse events due to drug-drug interactions
CONCLUSIONS: Our results show a high number of TDDIs detected were detected between NMV-r and other drugs. This study provides greater knowledge of the drugs involved in such interactions and their potential relationship with the occurrence of adverse events.PMID:37714801 | DOI:10.1016/j.farma.2023.08.005
Source: Farmacia Hospitalaria - September 15, 2023 Category: Drugs & Pharmacology Authors: Álvaro González-Gómez Jose Manuel Caro-Teller Iv án González-Barrios Almudena Castro-Fronti ñán Pedro Pablo Rodr íguez-Quesada Jos é Miguel Ferrari-Piquero Source Type: research

A comprehensive health risk assessment associated with bioaccumulation of heavy metals and nutrients in selected macrophytes of Loktak Lake, Manipur, India
Environ Sci Pollut Res Int. 2023 Sep 15. doi: 10.1007/s11356-023-29606-2. Online ahead of print.ABSTRACTThe Loktak Lake, a Ramsar site in Northeast India, is known for its rich biodiversity that includes a variety of macrophyte species, most of which have not been studied for their phytoremediation capacities and potential toxicity via consumption of the edible species. Therefore, a comprehensive assessment was conducted to evaluate the accumulation of selected heavy metals and nutrients in 10 dominant macrophyte species growing in Loktak Lake and to assess the potential health risks associated with consumption of the edib...
Source: Environmental Science and Pollution Research International - September 15, 2023 Category: Environmental Health Authors: Ranu Jajo Laishram Tensubam Basanta Singh Wazir Alam Source Type: research

Damage mechanism of calcium peroxide on Microcystis aeruginosa PCC7806 and its potential application
Ecotoxicol Environ Saf. 2023 Sep 13;264:115466. doi: 10.1016/j.ecoenv.2023.115466. Online ahead of print.ABSTRACTCalcium peroxide (CP) is an oxidizing agent that can gradually release hydrogen peroxide (HP) to achieve selective killing of cyanobacteria in water blooms, and reduce the phosphorus content in the water column. Despite the potential of CP for use in cyanobacterial water bloom disposal, there is a lack of research on the mechanism of oxidative damage on cyanobacterial cells by calcium peroxide. Further studies are required to comprehend the underlying scientific principles and potential risks and benefits of app...
Source: Ecotoxicology and Environmental Safety - September 15, 2023 Category: Environmental Health Authors: Yuheng Zhang Pengfei Qiu Yonghong Bi Dong Wan Wujuan Mi Chuming Tian Changen Qiu Gaofei Song Source Type: research