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Total 42422 results found since Jan 2013.

Pop-up screening nested within routine community activities unmasks an addressed cardiovascular risk: A pilot study (Gippsland Healthy Heart Study)
CONCLUSIONS: This study supported the feasibility and effectiveness of pop-up screening to detect CVRF in rural communities.PMID:37735862 | DOI:10.1111/ajr.13042
Source: The Australian Journal of Rural Health - September 22, 2023 Category: Rural Health Authors: Masashi Fujino Julie Butters Mark Boyes Noel Duncan Fleur Streets Amy Sabatini Alan Herschtal Adam J Nelson Stephen J Nicholls Source Type: research

Low-density lipoprotein subclasses over the menopausal transition and risk of coronary calcification and carotid atherosclerosis: the SWAN Heart and HDL ancillary studies
CONCLUSIONS: During the MT, women experience significant increases in LDL subclasses found to be related to greater cIMT levels and CAC prevalence. Whether these changes could better predict future risk of hard cardiovascular disease events beyond LDL-C remains a research question to address.PMID:37738035 | DOI:10.1097/GME.0000000000002245
Source: Atherosclerosis - September 22, 2023 Category: Cardiology Authors: Samar R El Khoudary Xirun Chen Ziyuan Wang Maria M Brooks Trevor Orchard Sybil Crawford Imke Janssen Susan A Everson-Rose Daniel McConnell Karen Matthews Source Type: research

Effects of < em > Aeriscardovia aeriphila < /em > on growth performance, antioxidant functions, immune responses, and gut microbiota in broiler chickens
In conclusion, oral administration of A. aeriphila could improve the growth performance, serum antioxidant capacity, immune modulation, and gut health of broilers. Our findings may provide important information for the application of A. aeriphila in poultry production.PMID:37735944 | DOI:10.1631/jzus.B2200621
Source: J Zhejiang Univ Sci ... - September 22, 2023 Category: Science Authors: Muhammad Zahid Farooq Xinkai Wang Xianghua Yan Source Type: research

Robustness of Heteroaggregates Involving Hydrophobic Cholesterol and its Mimetics
Phys. Chem. Chem. Phys., 2023, Accepted Manuscript DOI: 10.1039/D3CP02174B, PaperRituparna Hazra, Durba Roy Exploring the self and cross aggregation affinity of cholesterol (CHL) and some of its lookalikes, e.g., cholesteryl hemisuccinate (CHM), campesterol (CAM) and arjunic acid (ARJ) provides crucial understanding towards the... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 21, 2023 Category: Chemistry Authors: Rituparna Hazra Source Type: research

Effects of epicatechin on cardiovascular function in middle-aged diet-induced obese rat models of metabolic syndrome
This study aimed to investigate the cardiovascular effects of epicatechin, a flavonoid found in green tea and cocoa, in attenuating complications associated with metabolic syndrome in diet-induced obese rats.Male Wistar-Kyoto (WKY) rats aged 16 weeks were fed either standard rat chow (SC) or given a high-fat-high-carbohydrate (HFHC) diet for 20 weeks. Epicatechin treatment (5mg/kg/day) was administered to a subset of WKY rats commencing at week 8 of the 20 week HFHC feeding period. Body weights, food, water and energy intakes, blood pressure, heart rate and glucose tolerance were measured throughout the treatment period. O...
Source: The British Journal of Nutrition - September 21, 2023 Category: Nutrition Authors: Kylie Connolly Romeo Batacan Douglas Jackson Andrew Fenning Source Type: research

Single-Cell Hemoprotein Diet Changes Adipose Tissue Distributions and Re-Shapes Gut Microbiota in High-Fat Diet-Induced Obese Mice
This study suggests the potential of heme-SCP as an anti-obesity supplement, which modulates serum biochemistry and gut mi-crobiota in high-fat diet-induced obese mice.PMID:37734921 | DOI:10.4014/jmb.2308.08046
Source: Journal of Microbiology and Biotechnology - September 21, 2023 Category: Biotechnology Authors: Seungki Lee Ahyoung Choi Kyung-Hoon Park Youngjin Cho Hyunjin Yoon Pil Kim Source Type: research

Soluble receptor for advanced glycation end-products (sRAGE) in childhood obesity: association with gene expression of RAGE and cardiometabolic markers
CONCLUSIONS: expression of RAGE is associated with lower sRAGE levels in childhood obesity. Moreover, obese children show higher cardiometabolic risk markers, and a positively associated with sRAGE.PMID:37732356 | DOI:10.20960/nh.04666
Source: Nutricion Hospitalaria - September 21, 2023 Category: Nutrition Authors: Celia Aradillas-Garc ía Mariela Vega-C árdenas Juan Manuel Vargas-Morales Diana Patricia Portales-P érez Armando G ómez-Ojeda Claudia Luevano-Contreras Source Type: research

J-filter: An experiment to simplify and isolate specific signals in < sup > 1 < /sup > H NMR spectra of complex mixtures based on scalar coupling constants
Magn Reson Chem. 2023 Sep 19. doi: 10.1002/mrc.5396. Online ahead of print.ABSTRACTOne-dimensional selective NMR experiments relying on a J-filter element are proposed to isolate specific signals in crowded 1 H spectral regions. The J-filter allows the edition or filtering of signals in a region of interest of the spectrum by exploiting the specific values of their 1 H-1 H coupling constants and certain parameters of protons coupled to them that appear in less congested parts of the spectrum (chemical shifts and coupling constants). The new experiments permitted the isolation of specific peaks of phytosterol components in ...
Source: Magnetic Resonance in Chemistry : MRC - September 20, 2023 Category: Chemistry Authors: Karen V G óñez Juan Su árez García F Javier Sardina Yolanda Pazos Ángela Saá Manuel Mart ín Pastor Source Type: research

Sex differences in lipids: A life course approach
Atherosclerosis. 2023 Sep 1:117270. doi: 10.1016/j.atherosclerosis.2023.117270. Online ahead of print.ABSTRACTDifferences between men and women in lipids and lipoproteins are observed in distribution and trajectory from infancy to adulthood in the general population. However, these differences are more pronounced in hereditary lipid disorders such as familial hypercholesterolemia (FH) when absolute cholesterol levels are higher from birth onwards. In the early life course, girls compared to boys have higher low-density lipoprotein cholesterol (LDL-C) levels and total cholesterol, while high-density lipoprotein cholesterol ...
Source: Atherosclerosis - September 20, 2023 Category: Cardiology Authors: Kirsten B Holven Jeanine Roeters van Lennep Source Type: research

AMPK activators suppress cholesterol accumulation in macrophages via suppression of the mTOR pathway
In this study, we found that activation of AMPK by AICAR and metformin inhibits foam cell formation via suppression of mTOR in macrophages. Specifically, activation of AMPK indirectly reduced the phosphorylation level of mTOR at Ser2448 and promoted the expression of cholesterol efflux transporters and cholesterol efflux. These inhibitory effects on foam cell formation were counteracted by mTOR activators. Metformin, a more nonspecific AMPK activator than AICAR, appears to inhibit foam cell formation via anti-inflammatory effects in addition to suppression of the mTOR pathway. The results of this study suggest that the dev...
Source: Atherosclerosis - September 20, 2023 Category: Cardiology Authors: Reina Owaki Hiromasa Aoki Kohki Toriuchi Yasumichi Inoue Hidetoshi Hayashi Satoru Takeshita Hiroki Kakita Yasumasa Yamada Mineyoshi Aoyama Source Type: research

EXPRESS: Association between monocyte to high-density lipoprotein-cholesterol (HDL-C) ratio and osteoporosis: an analysis of the National Health and Nutrition Examination Survey (NHANES) 2013-2014
This study aimed to assess the relationship between monocyte-to-HDL-C ratio and osteoporosis. Participants aged ≥50 years with complete bone mineral density (BMD), monocyte, and HDL-C examination data from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 were included. Descriptive analysis was performed separately according to males and females. Weight linear regression and weight logistic regression analyses were used to analyze the association between monocyte-to-HDL-C ratio and BMD and osteopenia and osteoporosis and vertebral fracture. A total of 1,804 participants were included. Among the part...
Source: Atherosclerosis - September 20, 2023 Category: Cardiology Authors: Fushan Zhou Liyong Wu Guizhou Shen Xintan Chen Chaoyang Liu Dongqin Huang Mingmei Li Chengwei Xie Ruyu Zhan Source Type: research

AMPK activators suppress cholesterol accumulation in macrophages via suppression of the mTOR pathway
In this study, we found that activation of AMPK by AICAR and metformin inhibits foam cell formation via suppression of mTOR in macrophages. Specifically, activation of AMPK indirectly reduced the phosphorylation level of mTOR at Ser2448 and promoted the expression of cholesterol efflux transporters and cholesterol efflux. These inhibitory effects on foam cell formation were counteracted by mTOR activators. Metformin, a more nonspecific AMPK activator than AICAR, appears to inhibit foam cell formation via anti-inflammatory effects in addition to suppression of the mTOR pathway. The results of this study suggest that the dev...
Source: Experimental Cell Research - September 20, 2023 Category: Cytology Authors: Reina Owaki Hiromasa Aoki Kohki Toriuchi Yasumichi Inoue Hidetoshi Hayashi Satoru Takeshita Hiroki Kakita Yasumasa Yamada Mineyoshi Aoyama Source Type: research

Lipid metabolism and renal function markers in obese adolescents
CONCLUSIONS: Renal function of the obese adolescents included in the study was normal and the associations with lipid metabolism were poorly expressed.PMID:37728460 | DOI:10.5114/pedm.2023.125612
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Aleksandra Radosz Anna Obuchowicz Source Type: research

Are menstrual disorders in adolescent girls related to metabolic disorders?
CONCLUSIONS: Adolescent girls with menstrual disorders are insulin resistant, regardless of PCOS diagnosis. The severity of menstrual disorders may be related to the incidence of lipid disorders in adolescent girls.PMID:37728458 | DOI:10.5114/pedm.2023.125364
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: El żbieta Foryś Adrianna Baran Aleksandra Dziurdzia Ewelina Jarosz-W ójcik Pawe ł Matusik Aneta Gawlik Ryszard Tomaszewski Agnieszka Zachurzok Source Type: research

AMPK activators suppress cholesterol accumulation in macrophages via suppression of the mTOR pathway
In this study, we found that activation of AMPK by AICAR and metformin inhibits foam cell formation via suppression of mTOR in macrophages. Specifically, activation of AMPK indirectly reduced the phosphorylation level of mTOR at Ser2448 and promoted the expression of cholesterol efflux transporters and cholesterol efflux. These inhibitory effects on foam cell formation were counteracted by mTOR activators. Metformin, a more nonspecific AMPK activator than AICAR, appears to inhibit foam cell formation via anti-inflammatory effects in addition to suppression of the mTOR pathway. The results of this study suggest that the dev...
Source: Cell Research - September 20, 2023 Category: Cytology Authors: Reina Owaki Hiromasa Aoki Kohki Toriuchi Yasumichi Inoue Hidetoshi Hayashi Satoru Takeshita Hiroki Kakita Yasumasa Yamada Mineyoshi Aoyama Source Type: research