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Effects of combined strength and endurance training on exercise capacity in kidney transplant cyclists and runners
CONCLUSIONS: These findings indicate that the combined strength and endurance training is well tolerated and may improve exercise performance in this selected population of KTRs.PMID:37712239 | DOI:10.4415/ANN_23_03_07
Source: Ann Ist Super Sanita - September 15, 2023 Category: Biomedical Science Authors: Valentina Totti Rocco Di Michele Giulio Sergio Roi Sandro Bartolomei Giovanni Mosconi Gianluigi Sella Alessandro Nanni Costa Gabriela Sangiorgi Manuela Trerotola Lia Bellis Franco Merni Massimo Cardillo Source Type: research
Enhancing stability of liposomes using high molecular weight chitosan to promote antioxidative stress effects and lipid-lowering activity of encapsulated lutein in vivo and in vitro
Int J Biol Macromol. 2023 Sep 13:126564. doi: 10.1016/j.ijbiomac.2023.126564. Online ahead of print.ABSTRACTLutein is an antioxidant with multiple beneficial functions. However, its therapeutic potential is hampered by its low water solubility and bioavailability. The goal of this study is to compare the stability of lutein-loaded liposomes (Lu-lip) and low (LC)/high molecular weight (HC) chitosan-coated Lu-lip, along with their antioxidant capacity using H2O2-induced HepG2 cells and their lipid-lowering activity using high-fat diet mice. Both LC and HC reduced the lutein degradation rate by 17.5 % and 26.72 % in a challen...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Gaoshuai Zhang Meijing Zhang Yiqiao Pei Kun Qian Jiao Xie Qun Huang Suwen Liu Na Xue Yujiao Zu Hao Wang Source Type: research
Statin as repurposed drug in Ovarian Cancer: A comprehensive review
Curr Pharm Des. 2023 Sep 13. doi: 10.2174/1381612829666230913113808. Online ahead of print.ABSTRACTWith a prevalence rate of 6.6 per 100,000 women, ovarian cancer is the third most lethal gynecological tumor in the world. Several factors like family history, nulliparity, late menopause, genetic mutation, and an unhealthy lifestyle contribute to increasing the risk of ovarian cancer development. Novel research studies suggest that ovarian cancer may be caused by changes in the lipid metabolic profile that trigger inflammatory responses. Moreover, ovarian cancer patients will eventually experience chemoresistance. Statin, a ...
Source: Current Pharmaceutical Design - September 15, 2023 Category: Drugs & Pharmacology Authors: Asmara Ahmad Sadia Javed Shumaila Kiran Source Type: research
ANGPTL3 Deficiency and Risk of Hepatic Steatosis
CONCLUSIONS: ANGPTL3 deficiency related to LoF mutations in ANGPTL3, as well as genetically determined reduction of plasma ANGPTL3 levels, is not associated with hepatic steatosis. Therapeutic approaches to inhibit ANGPTL3 production in hepatocytes are not necessarily expected to result in the increased risk for hepatic steatosis that was observed with vupanorsen.PMID:37712257 | DOI:10.1161/CIRCULATIONAHA.123.065866
Source: Circulation - September 15, 2023 Category: Cardiology Authors: Laura D'Erasmo Michele Di Martino Thomas Neufeld Tyler J Fraum Chul Joo Kang Kendall H Burks Alessia Di Costanzo Ilenia Minicocci Simone Bini Marianna Maranghi Giovanni Pigna Giancarlo Labbadia Jie Zheng Davide Fierro Anna Montali Fabrizio Ceci Carlo Cata Source Type: research
Enhancing stability of liposomes using high molecular weight chitosan to promote antioxidative stress effects and lipid-lowering activity of encapsulated lutein in vivo and in vitro
Int J Biol Macromol. 2023 Sep 13:126564. doi: 10.1016/j.ijbiomac.2023.126564. Online ahead of print.ABSTRACTLutein is an antioxidant with multiple beneficial functions. However, its therapeutic potential is hampered by its low water solubility and bioavailability. The goal of this study is to compare the stability of lutein-loaded liposomes (Lu-lip) and low (LC)/high molecular weight (HC) chitosan-coated Lu-lip, along with their antioxidant capacity using H2O2-induced HepG2 cells and their lipid-lowering activity using high-fat diet mice. Both LC and HC reduced the lutein degradation rate by 17.5 % and 26.72 % in a challen...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Gaoshuai Zhang Meijing Zhang Yiqiao Pei Kun Qian Jiao Xie Qun Huang Suwen Liu Na Xue Yujiao Zu Hao Wang Source Type: research
Effects of combined strength and endurance training on exercise capacity in kidney transplant cyclists and runners
CONCLUSIONS: These findings indicate that the combined strength and endurance training is well tolerated and may improve exercise performance in this selected population of KTRs.PMID:37712239 | DOI:10.4415/ANN_23_03_07
Source: Ann Ist Super Sanita - September 15, 2023 Category: Biomedical Science Authors: Valentina Totti Rocco Di Michele Giulio Sergio Roi Sandro Bartolomei Giovanni Mosconi Gianluigi Sella Alessandro Nanni Costa Gabriela Sangiorgi Manuela Trerotola Lia Bellis Franco Merni Massimo Cardillo Source Type: research
2023 Chinese guideline for lipid management
Front Pharmacol. 2023 Aug 29;14:1190934. doi: 10.3389/fphar.2023.1190934. eCollection 2023.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among urban and rural residents in China, and elevated low-density lipoprotein cholesterol (LDL-C) is a risk factor for ASCVD. Considering the increasing burden of ASCVD, lipid management is of the utmost importance. In recent years, research on blood lipids has made breakthroughs around the world, hence a revision of Chinese guideline for lipid management is imperative, especially since the target lipid levels in the general population vary in respe...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Jian-Jun Li Shui-Ping Zhao Dong Zhao Guo-Ping Lu Dao-Quan Peng Jing Liu Zhen-Yue Chen Yuan-Lin Guo Na-Qiong Wu Sheng-Kai Yan Zeng-Wu Wang Run-Lin Gao Source Type: research
Effects of combined strength and endurance training on exercise capacity in kidney transplant cyclists and runners
CONCLUSIONS: These findings indicate that the combined strength and endurance training is well tolerated and may improve exercise performance in this selected population of KTRs.PMID:37712239 | DOI:10.4415/ANN_23_03_07
Source: Annali dell'Istituto Superiore di Sanita - September 15, 2023 Category: International Medicine & Public Health Authors: Valentina Totti Rocco Di Michele Giulio Sergio Roi Sandro Bartolomei Giovanni Mosconi Gianluigi Sella Alessandro Nanni Costa Gabriela Sangiorgi Manuela Trerotola Lia Bellis Franco Merni Massimo Cardillo Source Type: research
Statin as repurposed drug in Ovarian Cancer: A comprehensive review
Curr Pharm Des. 2023 Sep 13. doi: 10.2174/1381612829666230913113808. Online ahead of print.ABSTRACTWith a prevalence rate of 6.6 per 100,000 women, ovarian cancer is the third most lethal gynecological tumor in the world. Several factors like family history, nulliparity, late menopause, genetic mutation, and an unhealthy lifestyle contribute to increasing the risk of ovarian cancer development. Novel research studies suggest that ovarian cancer may be caused by changes in the lipid metabolic profile that trigger inflammatory responses. Moreover, ovarian cancer patients will eventually experience chemoresistance. Statin, a ...
Source: Current Pharmaceutical Design - September 15, 2023 Category: Drugs & Pharmacology Authors: Asmara Ahmad Sadia Javed Shumaila Kiran Source Type: research
ANGPTL3 Deficiency and Risk of Hepatic Steatosis
CONCLUSIONS: ANGPTL3 deficiency related to LoF mutations in ANGPTL3, as well as genetically determined reduction of plasma ANGPTL3 levels, is not associated with hepatic steatosis. Therapeutic approaches to inhibit ANGPTL3 production in hepatocytes are not necessarily expected to result in the increased risk for hepatic steatosis that was observed with vupanorsen.PMID:37712257 | DOI:10.1161/CIRCULATIONAHA.123.065866
Source: Circulation - September 15, 2023 Category: Cardiology Authors: Laura D'Erasmo Michele Di Martino Thomas Neufeld Tyler J Fraum Chul Joo Kang Kendall H Burks Alessia Di Costanzo Ilenia Minicocci Simone Bini Marianna Maranghi Giovanni Pigna Giancarlo Labbadia Jie Zheng Davide Fierro Anna Montali Fabrizio Ceci Carlo Cata Source Type: research
Effects of combined strength and endurance training on exercise capacity in kidney transplant cyclists and runners
CONCLUSIONS: These findings indicate that the combined strength and endurance training is well tolerated and may improve exercise performance in this selected population of KTRs.PMID:37712239 | DOI:10.4415/ANN_23_03_07
Source: Annali dell'Istituto Superiore di Sanita - September 15, 2023 Category: International Medicine & Public Health Authors: Valentina Totti Rocco Di Michele Giulio Sergio Roi Sandro Bartolomei Giovanni Mosconi Gianluigi Sella Alessandro Nanni Costa Gabriela Sangiorgi Manuela Trerotola Lia Bellis Franco Merni Massimo Cardillo Source Type: research
