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Total 70189 results found since Jan 2013.
Necrotizing pneumonia due to Aspergillus and Salmonella after immune checkpoint inhibitor treatment: An unusual case and review of the literature
CONCLUSIONS: Awareness of unusual pathogens in the etiology of pneumonia after ICI treatment may help to avoid underdiagnosis.PMID:37714729 | DOI:10.1016/j.riam.2023.05.001
Source: Revista Iberoamericana de Micologia - September 15, 2023 Category: Biology Authors: Muhammed Cihan I şık O ğuz Karcıoğlu G ülşen Hazırolan Dolunay G ülmez Mehmet Ruhi Onur Mehmet Mahir Kunt Sevtap Arikan-Akdagli G ökhan Metan Source Type: research
Selecting Triple Negative Breast Cancer Patients for Immunotherapy
Surg Oncol Clin N Am. 2023 Oct;32(4):733-745. doi: 10.1016/j.soc.2023.05.005. Epub 2023 Jun 5.ABSTRACTThe approval of preoperative immunotherapy combined with chemotherapy is a practice-changing advance for patients with early-stage triple-negative breast cancer. The optimal patient selection requires careful attention to staging and balancing potential risks with expected benefits, particularly as it relates to immune-related adverse events.PMID:37714640 | DOI:10.1016/j.soc.2023.05.005
Source: Clinical Breast Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Stephanie Downs-Canner Elizabeth A Mittendorf Source Type: research
Evidence-Based Strategies to Minimize the Likelihood of Axillary Lymph Node Dissection in Clinically Node-Positive Patients Following Neoadjuvant Chemotherapy
Surg Oncol Clin N Am. 2023 Oct;32(4):693-703. doi: 10.1016/j.soc.2023.05.003. Epub 2023 Jun 9.ABSTRACTDe-escalation of axillary management after neoadjuvant chemotherapy in clinically node-positive patients is feasible. The current literature shows this may be accomplished by sentinel lymph node biopsy (SLNB) with the use of dual tracer and removal of at least 2 sentinel lymph nodes, or by targeted axillary dissection (TAD). The accuracy of TAD has been consistently shown as better than that of SLNB. However, these techniques should only be offered to select patients without extensive axillary disease, understanding that l...
Source: Clinical Breast Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Ashley A Woodfin Abigail S Caudle Source Type: research
Machine learning- and WGCNA-mediated double analysis based on genes associated with disulfidptosis, cuproptosis and ferroptosis for the construction and validation of the prognostic model for breast cancer
CONCLUSION: Multiplex analysis based on DRGs, CRGs and FRGs correlated strongly with BC, providing new insights for developing clinical prognostic tools and designing immunotherapy regimens for BC patients.PMID:37712959 | DOI:10.1007/s00432-023-05378-7
Source: Clinical Breast Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Lijun Xu Shanshan Wang Dan Zhang Yunxi Wu Jiali Shan Huixia Zhu Chongyu Wang Qingqing Wang Source Type: research
Correlation of an immune-related 8-gene panel with pathologic response to neoadjuvant chemotherapy in patients with primary breast cancers
In conclusion, we have identified eight immune-related genes that are associated with a favorable prognosis and positive responses to drugs. This 8-gene signature could potentially provide prognostic insights for breast cancer patients undergoing NACT.PMID:37713974 | DOI:10.1016/j.tranon.2023.101782
Source: Translational Oncology - September 15, 2023 Category: Cancer & Oncology Authors: Ling-Ming Tseng Chi-Cheng Huang Yi-Fang Tsai Ji-Lin Chen Ta-Chung Chao Jiun-I Lai Pei-Ju Lien Yen-Shu Lin Chin-Jung Feng Yen-Jen Chen Jen-Hwey Chiu Chih-Yi Hsu Chun-Yu Liu Source Type: research
Calcium signals and potential therapy targets in ovarian cancer (Review)
Int J Oncol. 2023 Nov;63(5):125. doi: 10.3892/ijo.2023.5573. Epub 2023 Sep 15.ABSTRACTOvarian cancer (OC) is a deadly disease. The poor prognosis and high lethality of OC are attributed to its high degrees of aggressiveness, resistance to chemotherapy and recurrence rates. Calcium ion (Ca2+) signaling has received attention in recent years, as it appears to form an essential part of various aspects of cancer pathophysiology and is a potential therapeutic target for OC treatment. Disruption of normal Ca2+ signaling pathways can induce changes in cell cycle progression, apoptosis, proliferation and migration and invasion, le...
Source: International Journal of Oncology - September 15, 2023 Category: Cancer & Oncology Authors: Fengying Deng Mengyu Fu Chenxuan Zhao Jiahui Lei Ting Xu Bingyu Ji Hongmei Ding Yueming Zhang Jie Chen Junlan Qiu Qinqin Gao Source Type: research
Role of the tripartite motif (TRIM) family in female genital neoplasms
Pathol Res Pract. 2023 Sep 9;250:154811. doi: 10.1016/j.prp.2023.154811. Online ahead of print.ABSTRACTThe tripartite motif proteins (TRIMs) family represents a class of highly conservative proteins which play a large regulatory role in molecular processes. Recently, increasing evidence has demonstrated a role of TRIMs in female genital neoplasms. Our review thereby aimed to provide an overview of the biological involvement of TRIMs in female genital neoplasms, to provide a better understanding of its role in the development and progression of such diseases, and emphasize its potential as targeted cancer therapy. Overall, ...
Source: Pathology, Research and Practice - September 15, 2023 Category: Pathology Authors: Tianyu Liu Jian Chen Jinjie Wu Qiqiao Du Junxiu Liu Silu Tan Yuwen Pan Shuzhong Yao Source Type: research
An Adaptable Nanoprobe Integrated with Quantitative T < sub > 1 < /sub > -mapping Mri for Accurate Differential Diagnosis of Multidrug-Resistant Lung Cancer
This article is protected by copyright. All rights reserved.PMID:37714524 | DOI:10.1002/adhm.202300684
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Aijun Shen Yanhong Sun Gangmin Wang Xianfu Meng Xihui Ren Qingxuan Wan Qi Lv Xiangbin Wang Jiong Ni Minghua Li Xiaolong Ma Yun Xu Yutao Jiang Fang Wang YingSheng Cheng Peijun Wang Source Type: research
Calcium signals and potential therapy targets in ovarian cancer (Review)
Int J Oncol. 2023 Nov;63(5):125. doi: 10.3892/ijo.2023.5573. Epub 2023 Sep 15.ABSTRACTOvarian cancer (OC) is a deadly disease. The poor prognosis and high lethality of OC are attributed to its high degrees of aggressiveness, resistance to chemotherapy and recurrence rates. Calcium ion (Ca2+) signaling has received attention in recent years, as it appears to form an essential part of various aspects of cancer pathophysiology and is a potential therapeutic target for OC treatment. Disruption of normal Ca2+ signaling pathways can induce changes in cell cycle progression, apoptosis, proliferation and migration and invasion, le...
Source: International Journal of Oncology - September 15, 2023 Category: Cancer & Oncology Authors: Fengying Deng Mengyu Fu Chenxuan Zhao Jiahui Lei Ting Xu Bingyu Ji Hongmei Ding Yueming Zhang Jie Chen Junlan Qiu Qinqin Gao Source Type: research
Machine learning- and WGCNA-mediated double analysis based on genes associated with disulfidptosis, cuproptosis and ferroptosis for the construction and validation of the prognostic model for breast cancer
CONCLUSION: Multiplex analysis based on DRGs, CRGs and FRGs correlated strongly with BC, providing new insights for developing clinical prognostic tools and designing immunotherapy regimens for BC patients.PMID:37712959 | DOI:10.1007/s00432-023-05378-7
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Lijun Xu Shanshan Wang Dan Zhang Yunxi Wu Jiali Shan Huixia Zhu Chongyu Wang Qingqing Wang Source Type: research
Subcutaneous emphysema and pneumomediastinum following orbital blowout pathological fracture in a cat with nasal lymphoma: a case report
CONCLUSIONS: This is a first case report of a massive subcutaneous emphysema and pneumomediastinum due to an orbital blowout pathological fracture following chemotherapy in feline nasal lymphoma in veterinary medicine.PMID:37715215 | DOI:10.1186/s12917-023-03722-0
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Ye-In Oh Heejeong Hong Tae-Hee Kim Kyuyong Kang Junghee Yoon Hwa-Young Youn Kyoung-Won Seo Source Type: research
Role of the tripartite motif (TRIM) family in female genital neoplasms
Pathol Res Pract. 2023 Sep 9;250:154811. doi: 10.1016/j.prp.2023.154811. Online ahead of print.ABSTRACTThe tripartite motif proteins (TRIMs) family represents a class of highly conservative proteins which play a large regulatory role in molecular processes. Recently, increasing evidence has demonstrated a role of TRIMs in female genital neoplasms. Our review thereby aimed to provide an overview of the biological involvement of TRIMs in female genital neoplasms, to provide a better understanding of its role in the development and progression of such diseases, and emphasize its potential as targeted cancer therapy. Overall, ...
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Tianyu Liu Jian Chen Jinjie Wu Qiqiao Du Junxiu Liu Silu Tan Yuwen Pan Shuzhong Yao Source Type: research
Molecular subtypes and prognostic models for predicting prognosis of lung adenocarcinoma based on miRNA-related genes
CONCLUSION: Such miRNA-associated target gene characterization could be useful for prognostic prediction and contribute to therapeutic decision-making in LUAD.PMID:37711127 | DOI:10.2174/0929867331666230914151943
Source: Current Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Yuxi Wei Wei Zhong Yalan Bi Xiaoyan Liu Qing Zhou Jia Liu Mengzhao Wang Hong Zhang Minjiang Chen Source Type: research
A web-based prediction model for long-term cancer-specific survival of middle-aged patients with early-stage gastric cancer: a multi-institutional retrospective study
CONCLUSION: This study developed and validated a new nomogram to predict CSS in middle-aged patients with EGC. The prediction model has unique and practical value and can help doctors carry out individualized treatment and judge prognosis.PMID:37712958 | DOI:10.1007/s00432-023-05405-7
Source: Pain Physician - September 15, 2023 Category: Anesthesiology Authors: Simeng Zhang Longbo Zheng Yuxia Zhang Yuan Gao Lei Liu Zinian Jiang Liang Wang Zheng Ma Jinhui Wu Jiansheng Chen Yun Lu Dongsheng Wang Source Type: research
Cancer Stem Cells in Carcinogenesis and Potential Role in Pancreatic Cancer
Curr Stem Cell Res Ther. 2023 Sep 14. doi: 10.2174/1574888X19666230914103420. Online ahead of print.ABSTRACTA poor prognosis is associated with pancreatic cancer because of resistance during treatment and early distant metastases. The discovery of cancer stem cells has opened up novel avenues for research into the biology and treatment of cancer. Many investigations have pointed out the role of these types of stem cells in the oncogenesis and progression of hematologic and solid malignancies, specifically. Due to the existence of cancer stem cells in the proliferation and preservation of pancreatic tumors, such malignancie...
Source: Current Stem Cell Research and Therapy - September 15, 2023 Category: Stem Cells Authors: Rishav Sharma Rishabha Malviya Source Type: research
