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Total 70189 results found since Jan 2013.
Molecular subtypes and prognostic models for predicting prognosis of lung adenocarcinoma based on miRNA-related genes
CONCLUSION: Such miRNA-associated target gene characterization could be useful for prognostic prediction and contribute to therapeutic decision-making in LUAD.PMID:37711127 | DOI:10.2174/0929867331666230914151943
Source: Current Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Yuxi Wei Wei Zhong Yalan Bi Xiaoyan Liu Qing Zhou Jia Liu Mengzhao Wang Hong Zhang Minjiang Chen Source Type: research
An Adaptable Nanoprobe Integrated with Quantitative T < sub > 1 < /sub > -mapping Mri for Accurate Differential Diagnosis of Multidrug-Resistant Lung Cancer
This article is protected by copyright. All rights reserved.PMID:37714524 | DOI:10.1002/adhm.202300684
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Aijun Shen Yanhong Sun Gangmin Wang Xianfu Meng Xihui Ren Qingxuan Wan Qi Lv Xiangbin Wang Jiong Ni Minghua Li Xiaolong Ma Yun Xu Yutao Jiang Fang Wang YingSheng Cheng Peijun Wang Source Type: research
Role of the tripartite motif (TRIM) family in female genital neoplasms
Pathol Res Pract. 2023 Sep 9;250:154811. doi: 10.1016/j.prp.2023.154811. Online ahead of print.ABSTRACTThe tripartite motif proteins (TRIMs) family represents a class of highly conservative proteins which play a large regulatory role in molecular processes. Recently, increasing evidence has demonstrated a role of TRIMs in female genital neoplasms. Our review thereby aimed to provide an overview of the biological involvement of TRIMs in female genital neoplasms, to provide a better understanding of its role in the development and progression of such diseases, and emphasize its potential as targeted cancer therapy. Overall, ...
Source: Pathology, Research and Practice - September 15, 2023 Category: Pathology Authors: Tianyu Liu Jian Chen Jinjie Wu Qiqiao Du Junxiu Liu Silu Tan Yuwen Pan Shuzhong Yao Source Type: research
A Patient Presenting for Dental Extraction After Completion of Chemotherapy
Dent Clin North Am. 2023 Oct;67(4):667-670. doi: 10.1016/j.cden.2023.05.020. Epub 2023 Jun 18.ABSTRACTAcute myeloid leukemia (AML) presents several oral manifestations, including gingival hyperplasia, pale mucosa, poor wound healing, petechiae, ecchymoses, candidiasis, recurrent herpes infection, and ulcerations in the oral mucosa. Chemotherapy is the first-line treatment of AML. Common dental complications of chemotherapy include mucositis, infections secondary to profound bone marrow aplasia, and gingival bleeding. When treating patients with AML, preparing a comprehensive treatment plan is essential to help minimize the...
Source: Herpes - September 15, 2023 Category: Infectious Diseases Authors: Walter W Hong Irene H Kim Brad M Hong Sophia Oak Mel Mupparapu Source Type: research
ASO Visual Abstract: Defining the Values and Quality of Life of Cancer Survivors Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: An International Survey Study
Ann Surg Oncol. 2023 Sep 15. doi: 10.1245/s10434-023-14175-y. Online ahead of print.NO ABSTRACTPMID:37715111 | DOI:10.1245/s10434-023-14175-y
Source: Ann Oncol - September 15, 2023 Category: Cancer & Oncology Authors: Chelsea M Knotts Mayar A Osman Aderinsola A Aderonmu Nathan Bahary Patrick L Wagner David L Bartlett Casey J Allen Source Type: research
Cancer Stem Cells in Carcinogenesis and Potential Role in Pancreatic Cancer
Curr Stem Cell Res Ther. 2023 Sep 14. doi: 10.2174/1574888X19666230914103420. Online ahead of print.ABSTRACTA poor prognosis is associated with pancreatic cancer because of resistance during treatment and early distant metastases. The discovery of cancer stem cells has opened up novel avenues for research into the biology and treatment of cancer. Many investigations have pointed out the role of these types of stem cells in the oncogenesis and progression of hematologic and solid malignancies, specifically. Due to the existence of cancer stem cells in the proliferation and preservation of pancreatic tumors, such malignancie...
Source: Current Stem Cell Research and Therapy - September 15, 2023 Category: Stem Cells Authors: Rishav Sharma Rishabha Malviya Source Type: research
Selecting Triple Negative Breast Cancer Patients for Immunotherapy
Surg Oncol Clin N Am. 2023 Oct;32(4):733-745. doi: 10.1016/j.soc.2023.05.005. Epub 2023 Jun 5.ABSTRACTThe approval of preoperative immunotherapy combined with chemotherapy is a practice-changing advance for patients with early-stage triple-negative breast cancer. The optimal patient selection requires careful attention to staging and balancing potential risks with expected benefits, particularly as it relates to immune-related adverse events.PMID:37714640 | DOI:10.1016/j.soc.2023.05.005
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Stephanie Downs-Canner Elizabeth A Mittendorf Source Type: research
Evidence-Based Strategies to Minimize the Likelihood of Axillary Lymph Node Dissection in Clinically Node-Positive Patients Following Neoadjuvant Chemotherapy
Surg Oncol Clin N Am. 2023 Oct;32(4):693-703. doi: 10.1016/j.soc.2023.05.003. Epub 2023 Jun 9.ABSTRACTDe-escalation of axillary management after neoadjuvant chemotherapy in clinically node-positive patients is feasible. The current literature shows this may be accomplished by sentinel lymph node biopsy (SLNB) with the use of dual tracer and removal of at least 2 sentinel lymph nodes, or by targeted axillary dissection (TAD). The accuracy of TAD has been consistently shown as better than that of SLNB. However, these techniques should only be offered to select patients without extensive axillary disease, understanding that l...
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Ashley A Woodfin Abigail S Caudle Source Type: research
Machine learning- and WGCNA-mediated double analysis based on genes associated with disulfidptosis, cuproptosis and ferroptosis for the construction and validation of the prognostic model for breast cancer
CONCLUSION: Multiplex analysis based on DRGs, CRGs and FRGs correlated strongly with BC, providing new insights for developing clinical prognostic tools and designing immunotherapy regimens for BC patients.PMID:37712959 | DOI:10.1007/s00432-023-05378-7
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Lijun Xu Shanshan Wang Dan Zhang Yunxi Wu Jiali Shan Huixia Zhu Chongyu Wang Qingqing Wang Source Type: research
Preclinical activity of selinexor in combination with eribulin in uterine leiomyosarcoma
In this study, we evaluated the effects of selinexor in combination with doxorubicin and eribulin in the LMS tumor model in vitro and in vivo. Treatment of selinexor combined with eribulin showed synergistic effects on tumor growth inhibition in SK-UT1 LMS-derived xenografts. Immunohistochemical assessment of the tumor tissues showed a significantly reduced expression of proliferation (Ki67) and XPO1 markers following combination therapy compared to the control group. Global transcriptome analyses on tumor tissue revealed that the combination therapy regulates genes from several key cancer-related pathways that are differe...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Sonam Mittal Ishaque Pulikkal Kadamberi Hua Chang Feng Wang Sudhir Kumar Shirng-Wern Tsaih Christopher J Walker Pradeep Chaluvally-Raghavan John Charlson Yosef Landesman Sunila Pradeep Source Type: research
Value of Echocardiography and Cardiac Magnetic resonance in assessing left ventricular function in breast and gastric cancer patients after Anthracycline Chemotherapy
CONCLUSION: Breast and gastric cancer patients exhibited elevated levels of hs-cTnT after 6 cycles of chemotherapy, indicating potential cardiotoxicity. Additionally, cardiac MRI and 2-dimensional ECHO showed good agreement in assessing left ventricular function, with ECHO tending to underestimate volume measurements compared to MRI.PMID:37715125 | PMC:PMC10504696 | DOI:10.1186/s12872-023-03495-2
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Chao-Long Jin Xue-Gong Shi Ting-Ting Wang Hong-Wen Li Ding-Xin Zhang Zhe Sheng Jie Xiao Yong-Qiang Yu Source Type: research
Prognostic Analysis of Prophylactic Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer: a Propensity Score-Matched Analysis
CONCLUSION: Our study showed that prophylactic HIPEC could prevent postoperative PM in patients with AGC and did not increase the incidence of postoperative complications. However, it was not found to be effective in the prevention of other metastases, such as hepatic metastases.PMID:37715013 | DOI:10.1007/s11605-023-05823-5
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Lei Liu Longbo Zheng Shanglong Liu Maoshen Zhang Simeng Zhang Zinian Jiang Chen Qin Dongsheng Wang Source Type: research
Necrotizing pneumonia due to Aspergillus and Salmonella after immune checkpoint inhibitor treatment: An unusual case and review of the literature
CONCLUSIONS: Awareness of unusual pathogens in the etiology of pneumonia after ICI treatment may help to avoid underdiagnosis.PMID:37714729 | DOI:10.1016/j.riam.2023.05.001
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Muhammed Cihan I şık O ğuz Karcıoğlu G ülşen Hazırolan Dolunay G ülmez Mehmet Ruhi Onur Mehmet Mahir Kunt Sevtap Arikan-Akdagli G ökhan Metan Source Type: research
Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy
J Control Release. 2023 Sep 13:S0168-3659(23)00603-X. doi: 10.1016/j.jconrel.2023.09.016. Online ahead of print.ABSTRACTNanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted cancer therapy due to their ability to overcome many of the key challenges currently being faced with conventional chemotherapy. These challenges include the diverse and often complex pathophysiology involving the progression of cancer, as well as the various biological barriers that circumvent therapeutic molecules reaching their target site in optimum concentration. The scientific evidence suggests that surface-funct...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Pratiksha Tiwari Krishna Yadav Ravi Prakash Shukla Shalini Gautam Disha Marwaha Madhu Sharma Prabhat Ranjan Mishra Source Type: research
Necrotizing pneumonia due to Aspergillus and Salmonella after immune checkpoint inhibitor treatment: An unusual case and review of the literature
CONCLUSIONS: Awareness of unusual pathogens in the etiology of pneumonia after ICI treatment may help to avoid underdiagnosis.PMID:37714729 | DOI:10.1016/j.riam.2023.05.001
Source: Revista Iberoamericana de Micologia - September 15, 2023 Category: Biology Authors: Muhammed Cihan I şık O ğuz Karcıoğlu G ülşen Hazırolan Dolunay G ülmez Mehmet Ruhi Onur Mehmet Mahir Kunt Sevtap Arikan-Akdagli G ökhan Metan Source Type: research
