Filtered By:
Cancer: Colorectal Cancer
This page shows you your search results in order of date. This is page number 9.
Order by Relevance | Date
Total 40091 results found since Jan 2013.
Colonoscopy Combined with Me-Nbi to Observe the Canceration Characteristics of Colon Polyps and the Correlation of RHOC Protein Expression
In conclusion, NICE classification under colonoscopy combined with magnifying colonoscopy has a good effect on colorectal lesions. Differential diagnostic value, RhoC protein is highly expressed in colon cancer and is closely related to the occurrence of colon cancer and the depth of lesion invasion. With the progression of colorectal adenomas, the expression of RhoC protein in the lesions gradually increased.PMID:37715435 | DOI:10.14715/cmb/2023.69.7.7
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: None Shuqi Xu None Weimin Chen None Yiming Chen None Xuanfu Xu None Ying Dai None Jianqing Chen None Wenhui Mo None Meng Ji None Yueyue Li None Wenjing Liu Source Type: research
Three cases of colon cancer in four generations of the Saudi family, caused by endogamous germline mutations
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):163-171. doi: 10.14715/cmb/2023.69.8.25.ABSTRACTVarious research pieces of evidence have been published in recent years, establishing the increasing prevalence of early colon cancer among young people. In this background, the current study aimed to analyze the reasons behind colon cancer recurrence among endogamous consanguineous cases in four generations of a single Saud family. For this study, the authors conducted the whole-exome sequencing analysis to screen for germline mutations in DNA samples from consanguineous cases within the family. After collecting the colon sam...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Dalal S Alshaya Tahani Mohamed Ibrahim Al-Hazani Mashael Alhumaidi Alotaibi Dalia Mostafa Domiaty Eman Alshehri Maha Abdulla Alwaili Amani Mohammed Alotaibi Areej Saud Jalal Alaa Ali AlQahtani Fatima Abdullah AlQassim Gadah Albasher Wedad Saeed Al-Qahtani Source Type: research
Prognosis of carcinoembryonic antigen (CEA) in stage I colorectal adenocarcinoma and development of a prediction model: a retrospective study based on the SEER database
CONCLUSION: Elevated CEA is a risk factor for stage I CCA, but not for MUC. And the nomogram is accurate enough to predict the risk and prognostic factors of CCA.PMID:37715832 | DOI:10.1007/s00432-023-05410-w
Source: Clinical Colorectal Cancer - September 16, 2023 Category: Cancer & Oncology Authors: Zhongbiao Chen Zhimin Lin Source Type: research
Multi-omics profiling reveals cellular pathways and functions regulated by ALDH1B1 in colon cancer cells
Chem Biol Interact. 2023 Sep 14:110714. doi: 10.1016/j.cbi.2023.110714. Online ahead of print.ABSTRACTColon cancer is the third leading cause of cancer death globally. Although early screenings and advances in treatments have reduced mortality since 1970, identification of novel targets for therapeutic intervention is needed to address tumor heterogeneity and recurrence. Previous work identified aldehyde dehydrogenase 1B1 (ALDH1B1) as a critical factor in colon tumorigenesis. To investigate further, we utilized a human colon adenocarcinoma cell line (SW480) in which the ALDH1B1 protein expression has been knocked down by 8...
Source: Chemico-Biological Interactions - September 16, 2023 Category: Molecular Biology Authors: Yewei Wang Zeljka Popovic Georgia Charkoftaki Rolando Garcia-Milian TuKiet T Lam David C Thompson Ying Chen Vasilis Vasiliou Source Type: research
A metabolomic investigation of serum perfluorooctane sulfonate and perfluorooctanoate
CONCLUSIONS: In this large metabolomic study, we observed robust positive associations with PFOS for several molecules. Further investigation of these metabolites may offer insight into PFOS-related biologic effects.PMID:37716341 | DOI:10.1016/j.envint.2023.108198
Source: Environment International - September 16, 2023 Category: Environmental Health Authors: Jongeun Rhee Erikka Loftfield Demetrius Albanes Tracy M Layne Rachael Stolzenberg-Solomon Linda M Liao Mary C Playdon Sonja I Berndt Joshua N Sampson Neal D Freedman Steven C Moore Mark P Purdue Source Type: research
Cancer cell-intrinsic PD-1: Its role in malignant progression and immunotherapy
Biomed Pharmacother. 2023 Sep 14;167:115514. doi: 10.1016/j.biopha.2023.115514. Online ahead of print.ABSTRACTProgrammed cell death protein-1 (PD-1), also called CD279, is coded by the PDCD1 gene and is constitutively expressed on the surface of immune cells. As a receptor and immune checkpoint, PD-1 can bind to programmed death ligand-1/programmed death ligand-2 (PD-L1/PD-L2) in tumor cells, leading to tumor immune evasion. Anti-PD-1 and anti-PD-L1 are important components in tumor immune therapy. PD-1 is also expressed as an intrinsic variant (iPD-1) in cancer cells where it plays important roles in malignant progression...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Muhua Chen Lei Bie Jieer Ying Source Type: research
Modeling Tumor Growth Using Partly Conditional Survival Models: A Case Study in Colorectal Cancer
CONCLUSION: The PC modeling approach offers flexible characterization of associations between longitudinal covariates, such as serially assessed tumor burden, and survival time. It can be applied to a variety of data of this nature and used as clinical trials are ongoing to incorporate new disease assessment information as it is accumulated, as indicated by an example from colorectal cancer.PMID:37713655 | DOI:10.1200/CCI.22.00203
Source: Clinical Colorectal Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Jessica R Flynn Michael Curry Binsheng Zhao Hao Yang Laurent Dercle Antonio Tito Fojo Dana E Connors Lawrence H Schwartz Mithat G önen Chaya S Moskowitz Source Type: research
Global burden of early-onset colorectal cancer among people aged 40-49 years from 1990 to 2019 and predictions to 2030
CONCLUSION: The current and future burden of EO-CRC among people aged 40-49 years is heavy. Substantial variation exists in disease burden across regions and countries. Urgent screening actions and policies are needed.PMID:37712957 | DOI:10.1007/s00432-023-05395-6
Source: Clinical Colorectal Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Xiaowei Tang Jieyu Peng Shu Huang Huan Xu Ping Wang Jiao Jiang Wei Zhang Xiaomin Shi Lei Shi Xiaolin Zhong Muhan L ü Source Type: research
Manganese-based nanoparticles for chemodynamic therapy of gastrointestinal cancer
CONCLUSION: MSN@Mn-GOx nanoparticles have good chemodynamic properties and a strong anti-tumor effect and provide a potential therapeutic option for gastric cancer.PMID:37712282 | DOI:10.12122/j.issn.1673-4254.2023.08.22
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Lin M Huang J Chen X Zhou Z Zhong W Lu X Huang T Liu Source Type: research
Retracted Functional characterization of the nitrogen permease regulator ‑like‑2 candidate tumor suppressor gene in colorectal cancer cell lines
Mol Med Rep. 2023 Nov;28(5):201. doi: 10.3892/mmr.2023.13088. Epub 2023 Sep 15.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the microscopic images shown in Fig. 1C on p. 3489 and the invasion assay images shown in Fig. 5 on p. 3491 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes. Moreover, unexpected similarities were identified comparing between a pair of the flow cytometric assay data panels in Fig. 4 on p. 3490, considering that these data were inten...
Source: Molecular Medicine - September 15, 2023 Category: Molecular Biology Authors: Ai-Yun Liu Ming-Na Liu Feng-Hua Pei Jing Chen Xin-Hong Wang Dan Liu Ya-Ju Du Bing-Rong Liu Source Type: research
The microRNA-4766/VEGFA axis mediates macrophage M2-type polarization to inhibit colorectal cancer proliferation and migration
CONCLUSION: Restoring miR-4766 expression to inhibit VEGFA expression promised to be a potential strategy to suppress CRC development.PMID:37713737 | DOI:10.1016/j.prp.2023.154767
Source: Pathology, Research and Practice - September 15, 2023 Category: Pathology Authors: Chen Chen Zhiguo Huang Xinyu Tan Ruolong Wang Jia Liu Mu Zhang Source Type: research
Metformin inhibits self-renewal of colorectal cancer stem cells by inhibiting mitochondrial oxidative phosphorylation
CONCLUSION: Metformin reduces mitochondrial oxidative phosphorylation and ROS levels by inhibiting mitochondrial complex Ⅰ, thereby suppressing Wnt signaling pathway to reduce selfrenewal ability of colorectal CSCs.PMID:37712263 | DOI:10.12122/j.issn.1673-4254.2023.08.03
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: C Yan S Liu Q Song Y Hu Source Type: research
Effect of perioperative airway management on postoperative outcomes of colorectal cancer patients with sarcopenia
CONCLUSION: The perioperative airway management program implemented at our center was easy to perform and can effectively improve short-term postoperative outcomes in colorectal cancer patients with sarcopenia.PMID:37713967 | DOI:10.1016/j.ejon.2023.102418
Source: European Journal of Oncology Nursing - September 15, 2023 Category: Nursing Authors: Tingting Xie Liyuan Li Xiangxiang Yang Xiaofen Wu Minmin Wang Weizhe Chen Qiantong Dong Xiaolei Chen Jiang Li Source Type: research
Correlation between High Incidence of Colorectal Neoplastic Polyps and High-risk Adenomas in Patients with Diabetes Mellitus: A Retrospective Study
CONCLUSION: This study demonstrated that patients with DM, age ≥ 50 years, male gender, alcohol consumption, and a first-degree relative with a history of CRC should undergo regular endoscopic screening and colonic polypectomy.PMID:37711116 | DOI:10.2174/1871530323666230913105743
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - September 15, 2023 Category: Endocrinology Authors: Chuan-Yu Zheng Wa Zhong Ji-Hao Xu Yu-Hong Yuan Nai-Zhao Chen Wei-Ling Liang Qi-Kui Chen Yu Lai Source Type: research
Manganese-based nanoparticles for chemodynamic therapy of gastrointestinal cancer
CONCLUSION: MSN@Mn-GOx nanoparticles have good chemodynamic properties and a strong anti-tumor effect and provide a potential therapeutic option for gastric cancer.PMID:37712282 | DOI:10.12122/j.issn.1673-4254.2023.08.22
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: X Lin M Huang J Chen X Zhou Z Zhong W Lu X Huang T Liu Source Type: research
