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Vaccination: Pneomococcal Vaccine

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Total 3041 results found since Jan 2013.

Exclusion of older adults and immunocompromised  individuals in influenza, pneumococcal and COVID-19 vaccine trials before and after the COVID-19 pandemic
CONCLUSIONS: During the COVID-19 pandemic, we found a decrease in the exclusion of older adults from vaccine trials but no significant change in the inclusion of immunocompromised individulas.PMID:37027085 | PMC:PMC10080508 | DOI:10.1007/s40520-023-02380-4
Source: Aging Clinical and Experimental Research - April 7, 2023 Category: Geriatrics Authors: Katrine Bukan Toby Pearce-Slade Mads Eiberg Marco Tinelli Dafna Yahav Jose Tuells Olivier Epaulard Jon G Holler Casper Roed Christian S øborg Jens-Ulrik St æhr Jensen Zitta Barrella Harboe Source Type: research

Obesity as an independent risk factor for COVID-19 severity and mortality
CONCLUSIONS: Our findings suggest that obesity is an important independent prognostic factor in the setting of COVID-19. Consideration of obesity may inform the optimal management and allocation of limited resources in the care of COVID-19 patients.PMID:37222292 | PMC:PMC10207996 | DOI:10.1002/14651858.CD015201
Source: Cochrane Database of Systematic Reviews - May 24, 2023 Category: General Medicine Authors: Borna Tadayon Najafabadi Daniel G Rayner Kamyar Shokraee Kamran Shokraie Parsa Panahi Paravaneh Rastgou Farnoosh Seirafianpour Feryal Momeni Landi Pariya Alinia Neda Parnianfard Nima Hemmati Behrooz Banivaheb Ramin Radmanesh Saba Alvand Parmida Shahbazi H Source Type: research

Pneumococcal vaccines for cystic fibrosis.
CONCLUSIONS: As no trials were identified we cannot draw conclusions on the efficacy of routine pneumococcal immunisation in people with cystic fibrosis in reducing their morbidity or mortality. As many countries now include pneumococcal immunisation in their routine childhood vaccination schedule it is unlikely that future randomised controlled trials will be initiated. Rigorously conducted epidemiological studies may offer the opportunity to evaluate the efficacy of pneumococcal vaccination in reducing morbidity and mortality in people with cystic fibrosis. PMID: 25093421 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - August 5, 2014 Category: Journals (General) Authors: Burgess L, Southern KW Tags: Cochrane Database Syst Rev Source Type: research

Recurrent Urinary Tract Infections in Women
This article provides an overview of recurrent UTIs and their management, using current information from systematic reviews, randomized controlled trials, and clinical guidelines. A literature search was conducted using MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews databases. Current guidelines on management of recurrent UTIs were obtained through use of a Google search. The authors recommend a pathway for the management of recurrent UTIs, based on the latest evidence. The criterion-standard test for definitive diagnosis of responsible uropathogens is urine microscopy and culture of midstream urine sampl...
Source: Obstetrical and Gynecological Survey - October 1, 2015 Category: OBGYN Tags: Gynecology: Urogynecology Source Type: research

You Decide: The Risks and Benefits of the MMR Vaccination
Most of us weigh the risks and benefits of medical procedures prior to obtaining them. We sign an informed consent form with an understanding of the potential harm versus the perceived benefits. In the case of vaccinations, the great majority of parents obtain vaccinations for their children, influenced by the “sales pitch” and “scare tactics” used by physicians. We are assured that the vaccination is safe and will protect us and our children from the various targeted deadly diseases. If we blindly trust our doctors, as I once had, we readily agree. It is important that we think critically before agreeing to any va...
Source: vactruth.com - February 18, 2016 Category: Allergy & Immunology Authors: Michelle Goldstein Tags: Logical Michelle Goldstein Top Stories autism Centers for Disease Control (CDC) MMR vaccine vaccine injury Source Type: blogs

Vaccines Blamed for Alarming Increase in Seizure Disorders Among Children
Conclusion Epilepsy is a serious medical condition with far-reaching implications for children, adults, and their families who are affected by this neurological disorder. Many different vaccines put children at an increased risk of developing epilepsy, and the effects of suffering repeated seizures can last for years or for a lifetime. Has your child suffered a seizure following vaccination? If so, please share your story in the comments below, and share this article with other parents to help them learn about the true risks of vaccines.   References: http://www.examiner.com/article/parents-question-vaccines… h...
Source: vactruth.com - July 25, 2016 Category: Allergy & Immunology Authors: Missy Fluegge Tags: Logical Missy Fluegge Top Stories Epilepsy seizures truth about vaccines Source Type: blogs

Pneumococcal vaccines for cystic fibrosis.
CONCLUSIONS: As no trials were identified we cannot draw conclusions on the efficacy of routine pneumococcal immunisation in people with cystic fibrosis in reducing their morbidity or mortality. As many countries now include pneumococcal immunisation in their routine childhood vaccination schedule it is unlikely that future randomised controlled trials will be initiated. Rigorously conducted epidemiological studies may offer the opportunity to evaluate the efficacy of pneumococcal vaccination in reducing morbidity and mortality in people with cystic fibrosis. PMID: 27654832 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 21, 2016 Category: Journals (General) Authors: Burgess L, Southern KW Tags: Cochrane Database Syst Rev Source Type: research

Burden of Culture-Confirmed Pediatric Pneumococcal Pneumonia in Latin America and the Caribbean: A Systematic Review and Meta-Analysis
Conclusions Studies on confirmed pediatric PP were scarce in LAC in 2000 to 2016. Epidemiology indicators and health resource use are still poorly defined.
Source: Value in Health Regional Issues - June 10, 2017 Category: International Medicine & Public Health Source Type: research

Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease.
CONCLUSIONS: The evidence examined suggests that prophylactic penicillin significantly reduces risk of pneumococcal infection in children with homozygous SCD, and is associated with minimal adverse reactions. Further research may help to determine the ideal age to safely withdraw penicillin. PMID: 28994899 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 10, 2017 Category: General Medicine Authors: Rankine-Mullings AE, Owusu-Ofori S Tags: Cochrane Database Syst Rev Source Type: research

Vaccinations in immunosuppressive-dependent pediatric inflammatory bowel disease.
CONCLUSION: Immunizations have been shown to be well-tolerated and protective immunity can be achieved in patients with IBD requiring immunosuppressive therapy. PMID: 29204064 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - November 14, 2017 Category: Gastroenterology Authors: Nguyen HT, Minar P, Jackson K, Fulkerson PC Tags: World J Gastroenterol Source Type: research

Grommets (ventilation tubes) for recurrent acute otitis media in children.
CONCLUSIONS: Current evidence on the effectiveness of grommets in children with rAOM is limited to five RCTs with unclear or high risk of bias, which were conducted prior to the introduction of pneumococcal vaccination. Low to very low-quality evidence suggests that children receiving grommets are less likely to have AOM recurrences compared to those managed by active monitoring and placebo medication, but the magnitude of the effect is modest with around one fewer episode at six months and a less noticeable effect by 12 months. The low to very low quality of the evidence means that these numbers need to be interpreted wit...
Source: Cochrane Database of Systematic Reviews - May 9, 2018 Category: General Medicine Authors: Venekamp RP, Mick P, Schilder AG, Nunez DA Tags: Cochrane Database Syst Rev Source Type: research

Six Ways Artificial Intelligence Is Impacting Patients
It ’s difficult to open a newspaper nowadays without seeing an article about artificial intelligence. These column-inches spark our imaginations with heady visions of possible futures and crease our brows with concern in equal measure. But one thing you cannot escape is that AI is here now and it’s only going to become more pervasive.While fear of an unknown technology is understandable, in many ways it does a disservice to the incredible impact that AI is already having on the world around us. In the healthcare space alone, it is offering ways to fundamentally rethink clinical practice, speeding up diagnosis, driving ...
Source: EyeForPharma - July 24, 2018 Category: Pharmaceuticals Authors: Lucy Fulford Source Type: news

Fight Aging! Newsletter, November 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - November 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Exploring the Potential Role of Moonlighting Function of the Surface-Associated Proteins From Mycobacterium bovis BCG Moreau and Pasteur by Comparative Proteomic
In this study, the proteomic profile of the surface-associated proteins from M. bovis BCG Moreau was compared to the BCG Pasteur reference strain. The methodology used was 2DE gel electrophoresis combined with mass spectrometry techniques (MALDI-TOF/TOF), leading to the identification of 115 proteins. Of these, 24 proteins showed differential expression between the two BCG strains. Furthermore, 27 proteins previously described as displaying moonlighting function were identified, 8 of these proteins showed variation in abundance comparing BCG Moreau to Pasteur and 2 of them presented two different domain hits. Moonlighting ...
Source: Frontiers in Immunology - April 25, 2019 Category: Allergy & Immunology Source Type: research

Safety and Efficacy of Anti-PD-1 Monoclonal Antibodies in Patients With Relapsed or Refractory Lymphoma: A Meta-Analysis of Prospective Clinic Trails
Conclusions: Nivolumab and pembrolizumab have promising outcomes with tolerable AEs and drug-related deaths in patients with relapsed or refractory lymphoma. Pembrolizumab caused less any grade AEs like fatigue and rash than nivolumab. Patients with HL got better response than NHL. Introduction Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor mainly expressed on activated T cells, natural killer cells, and B cells (Ishida et al., 1992). The PD-L1 and PD-L2 are its known ligands, which interact with PD-1 on T cells and prevent T-cell activation and proliferation. PD-L1 is expressed on macropha...
Source: Frontiers in Pharmacology - April 30, 2019 Category: Drugs & Pharmacology Source Type: research