Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease.
CONCLUSIONS: The evidence examined suggests that prophylactic penicillin significantly reduces risk of pneumococcal infection in children with homozygous SCD, and is associated with minimal adverse reactions. Further research may help to determine the ideal age to safely withdraw penicillin.
PMID: 28994899 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Rankine-Mullings AE, Owusu-Ofori S Tags: Cochrane Database Syst Rev Source Type: research
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