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Medical Research: The Best Investment We Can Make in Our Future
While the cure for cancer has been elusive, President Obama's National Cancer Moonshot initiative offers renewed hope that we could see breakthroughs in prevention, detection, and treatment for a disease that affects millions of Americans and their families. The cancer moonshot is the latest demonstration that Washington understands the potential for medical research to change lives and improve the health of all Americans. It builds on the bipartisan support we saw last fall when House and Senate negotiators agreed on a $2 billion budget increase for medical research through the National Institutes of Health (NIH). Today,...
Source: Science - The Huffington Post - February 18, 2016 Category: Science Source Type: news
Flu Shot Could Prevent a Heart Attack
The flu vaccine protects against more than just influenza ― it also reduces the risk of heart attack and stroke by about one-third, according to studies published by the British Medical Journal Heart and the Journal of the American Medical Association. This February during American Heart Month, Texas physicians urge everyone who hasn’t yet received an annual flu shot to get vaccinated.
Source: TMA News Room - February 22, 2016 Category: Consumer Health News Source Type: news
A bummer for kids: Nasal flu vaccine not effective
Follow me at @drClaire
Every year, many of my patients have been able to skip the needle — and still get vaccinated against the flu. That was the great thing about the nasal spray version of the flu vaccine, known as the LAIV (live attenuated influenza vaccine): kids scared of needles could get a squirt up each nostril and be all set.
This coming flu season, everyone is getting the shot.
It turns out that the nasal spray just didn’t work that well. Despite studies from the 2002-2003 and 2004-2005 flu seasons that seemed to show that the nasal spray actually worked better than the shot in children ages 2-8 years, over t...
Source: New Harvard Health Information - June 28, 2016 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Cold and Flu Infectious diseases Parenting Prevention Source Type: news
Flu vaccine may reduce risk of death for type 2 diabetes patients
( Imperial College London ) The flu vaccine may reduce the likelihood of being hospitalized with stroke and heart failure in people with type 2 diabetes, according to new research. The study, from scientists at Imperial College London, also found patients who received the influenza vaccination had a 24 per cent lower death rate in the flu season compared to patients who weren't vaccinated.
Source: EurekAlert! - Infectious and Emerging Diseases - July 25, 2016 Category: Infectious Diseases Source Type: news
Functional Food and dietary supplements For Lung Health
Conclusions This plant metabolites benefits lung health by anti-inflammatory, immune-modulatory, and antioxidant effects. Many pungent flavor components in edible plants activate the mucous membranes of the respiratory tract to help fight microbes and remove undesirable agents. These flavor and aroma compounds can behave as expectorants, decongestant, antitussive, and antimicrobial agents. They enhance mucous membrane secretion, kill pathogens, reduce inflammation and decrease mucous viscosity by weakening the hydrogen bonds in the mucous. For lung cancer, certain plant metabolites help induce apoptosis, suppress angiogene...
Source: Trends in Food Science and Technology - August 17, 2016 Category: Food Science Source Type: research
Effect of Air Temperature and Universal Thermal Climate Index on Respiratory Diseases Mortality in Mashhad, Iran.
CONCLUSION: Generally, mortality increases with decreasing temperature and increasing cold stresses and the mortality risk increases by 1.36% per 10°C reduction.
PMID: 27631176 [PubMed - in process]
Source: Archives of Iranian Medicine - August 31, 2016 Category: Middle East Health Authors: Fallah Ghalhari G, Mayvaneh F Tags: Arch Iran Med Source Type: research
Emergency Department Intervention May Reduce Suicide Attempts in At-Risk Patients
Astudy published April 29 inJAMA Psychiatry reports that a multifaceted intervention incorporating screening, safety planning guidance, and periodic telephone follow-up can reduce the risk of suicidal behavior in at-risk individuals who present in the emergency department (ED).The reductions were modest but clinically significant; compared with usual ED treatment, the number of patients who attempted suicide dropped by about 20% and the total number of suicide attempts dropped by about 30%.“We would like to have had an even stronger effect, but the fact that we were able to impact attempts with this population and w...
Source: Psychiatr News - May 2, 2017 Category: Psychiatry Tags: emergency department suicidal risk suicide prevention suicide screening Source Type: research
Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study
This study is registered with ClinicalTrials.gov, number NCT01052480. Findings Between Jan 13, 2011, and March 2, 2015, 113 participants were screened for eligibility and 98 were randomly assigned from 20 out of 29 participating sites. Of the participants with confirmed influenza (by PCR), 28 (67%) of 42 in the plasma plus standard care group normalised their respiratory status by day 28 compared with 24 (53%) of 45 participants on standard care alone (p=0·069). The hazard ratio (HR) comparing plasma plus standard care with standard care alone was 1·71 (95% CI 0·96–3·06). Six participants died, one (2%) from the plas...
Source: The Lancet Respiratory Medicine - May 16, 2017 Category: Respiratory Medicine Source Type: research
What Causes Microcephaly?
Discussion
Microcephaly is usually defined as an occipitofrontal head circumference (OFC) more than 2 standard deviations (SD) below the mean for sex, age and ethnicity. Severe microcephaly is used for OFC < 3 standard deviations. Rates of microcephaly range from 0.5-12 patients/10,000 live births.
The OFC should be measured at every well child visit and at other opportunities and plotted on standard growth charts. The OFC is measured using a nonelastic tape measure around the largest part of the head with the tape measure held above the eyebrows and ears. It is a highly reproducible measurement. There are several diff...
Source: PediatricEducation.org - September 25, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Infant Deaths and Mortality from Gun Violence: Causal or Casual?
CONCLUSIONS: In NYC, non-Hispanic black IM declined significantly despite increasing income inequality and was strongly correlated with gun-related assault mortality and other major causes of death. These data are compatible with the hypothesis that activities related to overall population health, including those pertaining to gun-related homicide, may provide clues to reducing IM. Analytic epidemiological studies are needed to test these and other hypotheses formulated from these descriptive data.
PMID: 29173931 [PubMed - in process]
Source: Journal of the National Medical Association - November 28, 2017 Category: General Medicine Tags: J Natl Med Assoc Source Type: research
The association of adult vaccination with the risk of cerebrovascular ischemia: A systematic review and meta-analysis
There is mounting evidence supporting infection as an independent risk factor for ischemic stroke (IS), while preliminary data indicate that vaccination may prevent IS. We performed a systematic review and meta-analysis of available randomized clinical trials (RCTs) or prospective observational cohorts reporting associations of influenza vaccination (IV) and/or pneumococcal vaccination (PV) with IS. We identified a total of 12 studies (543,311 patients; 47.4% vaccinated). Vaccination was not related to the risk of IS (RR=1.06, 95%CI: 0.74 –1.51, p=0.77), with no significant differences (p=0.26) among RCTs (RR=0.66, 95%CI...
Source: Journal of the Neurological Sciences - January 8, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Aristeidis H. Katsanos, Ramin Zand, Muhammad Fawad Ishfaq, Muhammad Taimur Malik, Theodore Karapanayiotides, Konstantinos Voumvourakis, Sotirios Tsiodras, John Parissis Source Type: research
Botany, traditional use, phytochemistry, pharmacology, quality control, and authentication of Radix Gentianae Macrophyllae-A traditional medicine: A review
Conclusions : Although the identification of compounds from Qinjiao and demonstration of medicinal uses in vitro and in vivo have been carried out, various other studies on these plants should deserve our more attention. More efforts should be concentrated on the underlying mechanisms of their beneficial bioactivities. The proper toxic evaluation is indispensable to guarantee the safety, efficacy, and eligibility for medical use. To sum up, the summarized achievements could highlight the importance of Qinjiao and provide a solid foundation for scientists not only to further exploit the therapeutic potentials, but also poss...
Source: Phytomedicine - April 12, 2018 Category: Drugs & Pharmacology Source Type: research
Reversible lesions of the corpus callosum with initially restricted diffusion in a series of Caucasian children
ConclusionA transient lesion of the corpus callosum with restricted diffusion should prompt the radiologist to suggest an infectious trigger in children. The prognosis of these patients was good with normalization of clinical symptoms and MRI without any specific treatment.
Source: Pediatric Radiology - June 14, 2018 Category: Radiology Source Type: research
A True Hematologic Emergency
BY GREGORY TAYLOR, DO, & JACKLYN MCPARLANE, DOA 33-year-old woman with a past medical history of sickle cell SS presented to the emergency department with chest pain, difficulty breathing, and a cough for two days. Her chest pain was diffuse, without radiation, and partially reproducible. Her cough was nonproductive, and she also reported fever and chills.The patient noted this was different from her normal back and leg pain from past sickle cell crises. She was following up with a sickle cell specialist, and was compliant with her hydroxyurea treatment.Her temperature was 102.8°F, blood pressure was 94/60 mm...
Source: The Case Files - June 26, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research
Botany, traditional use, phytochemistry, pharmacology, quality control, and authentication of Radix Gentianae Macrophyllae-A traditional medicine: A review
Conclusions: Although the identification of compounds from Qinjiao and demonstration of medicinal uses in vitro and in vivo have been carried out, various other studies on these plants should deserve our more attention. More efforts should be concentrated on the underlying mechanisms of their beneficial bioactivities. The proper toxic evaluation is indispensable to guarantee the safety, efficacy, and eligibility for medical use. To sum up, the summarized achievements could highlight the importance of Qinjiao and provide a solid foundation for scientists not only to further exploit the therapeutic potentials, but also possi...
Source: Phytomedicine - July 5, 2018 Category: Drugs & Pharmacology Source Type: research
