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The effect of exercise on vascular health in chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials
Am J Physiol Renal Physiol. 2023 Sep 21. doi: 10.1152/ajprenal.00152.2023. Online ahead of print.ABSTRACTPatients with chronic kidney disease (CKD) are at increased risk of cardiovascular disease. This increased risk cannot be fully explained by traditional risk factors such as hypertension. Endothelial dysfunction and arterial stiffness have been suggested as factors which explain some of the increased risk, and are independently associated with important cardiovascular outcomes in CKD patients. Studies in other disease populations have shown positive effects of exercise on vascular dysfunction. The aim of this review was...
Source: Am J Physiol Renal P... - September 21, 2023 Category: Urology & Nephrology Authors: Mark D Davies Felicity Hughes Aamer Sandoo Abdulfattah Alejmi Jamie Hugo Macdonald Source Type: research

Identification of a TRP channel-related risk model for predicting prognosis and therapeutic effects of patients with hepatocellular carcinoma
CONCLUSIONS: We successfully established a highly accurate prognostic model for predicting overall survival and therapeutic effects using TRP channel-related genes.PMID:37733242 | DOI:10.1007/s00432-023-05394-7
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Chong Pang Zhe Xu Jilong Han Fujun Li Hongyan Zhu Jiaqi Zhang Dong Wang Xundi Xu Source Type: research

Patient evaluation of gynaecological information provision and preferences
CONCLUSION: Health professionals are central to women accessing information about gynaecological diagnoses. Areas for improvement include communication strategies, facilitating access to internet-based resources for information and consideration of women's preferences when providing health information.IMPLICATIONS FOR THE PROFESSION AND PATIENT CARE: Consumer co-design of gynaecological health information and communication training for health professionals is recommended. Improved communication and facilitated use of internet-based resources may improve women's understanding of information.IMPACT: This study explored gynae...
Source: Adv Data - September 21, 2023 Category: Epidemiology Authors: Natalie Williams Georgia Griffin Megan Wall Stuart Watson Jane Warland Zoe Bradfield Source Type: research

Identification of a TRP channel-related risk model for predicting prognosis and therapeutic effects of patients with hepatocellular carcinoma
CONCLUSIONS: We successfully established a highly accurate prognostic model for predicting overall survival and therapeutic effects using TRP channel-related genes.PMID:37733242 | DOI:10.1007/s00432-023-05394-7
Source: Clinical Genitourinary Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Chong Pang Zhe Xu Jilong Han Fujun Li Hongyan Zhu Jiaqi Zhang Dong Wang Xundi Xu Source Type: research

Benefits beyond cardiometabolic health: the potential of frequent high intensity 'exercise snacks' to improve outcomes for those living with and beyond cancer
J Physiol. 2023 Sep 21. doi: 10.1113/JP284985. Online ahead of print.ABSTRACTHigh intensity interval training (HIIT) has been shown to consistently elicit rapid and significant adaptations in a number of physiological systems, across many different healthy and clinical populations. In addition, there is increasing interest in how some acute, yet transient responses to high intensity exercise potentially reduce the risks of particular diseases. Recent work has shown that discrete, brief bouts of high intensity exercise (termed 'exercise snacks') can improve glucose control and vascular health and thus counter the negative c...
Source: The Journal of Physiology - September 21, 2023 Category: Physiology Authors: David G Jenkins James L Devin Kathryn L Weston Joseph G Jenkins Tina L Skinner Source Type: research

Development and Characterization of Proteomic Aging Clocks in the Atherosclerosis Risk in Communities (ARIC) Study
We examined their associations with mortality from all-cause, cardiovascular disease (CVD), cancer, and lower respiratory disease (LRD) using Cox proportional hazards regression in all remaining participants irrespective of health. The model was adjusted for chronological age, smoking, body mass index (BMI), and other confounders. The ARIC PACs had a slightly stronger correlation with chronological age than published PACs in healthy participants at each time point. Associations with mortality were similar for the ARIC and published PACs. For late-life and midlife age acceleration for the ARIC PACs, respectively, hazard rat...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Authors Shuo Wang Zexi Rao Rui Cao Anne H Blaes Josef Coresh Corinne E Joshu Benoit Lehallier Pamela L Lutsey James S Pankow Sanaz Sedaghat Weihong Tang Bharat Thyagarajan Keenan A Walker Peter Ganz Elizabeth A Platz Weihua Guan Anna Prizment Source Type: research

Effects of short-term supervised exercise training on liver fat in adolescents with obesity: a randomized controlled trial
CONCLUSIONS: The implemented exercise protocol did not reduce IHTG, but it led to modest improvement in markers of cardiometabolic health.PMID:37731271 | DOI:10.1002/oby.23887
Source: Obesity - September 21, 2023 Category: Eating Disorders & Weight Management Authors: Emir Tas Reid D Landes Eva C Diaz Shasha Bai Xiawei Ou Robert Buchmann Xiaoxu Na Radhika Muzumdar Elisabet B ørsheim Jonathan A Dranoff Source Type: research

Effect of Physical Exercise on Mitochondrial Dysfunction and Purkinje Cell Survival in the Cerebellum of 3xTg-AD Mice
CONCLUSIONS: These findings suggest that engaging in exercise training can offer protection against the progression of AD in the cerebellum by enhancing mitochondrial function and promoting cell survival.PMID:37735133 | DOI:10.31083/j.jin2205117
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Youngyun Jin Taewan Kim Taewoon Kim Source Type: research

Tai Ji on Cognitive Function Improvement in Parkinson's Disease: A Meta-Analysis
CONCLUSIONS: TJ affects the cognitive function of PD patients. However, this effect may have a reduced or no significant impact as the disease increases. PD patients can choose TJ as an intervention for 45-60 min twice a week for at least 12 weeks to accomplish maximum improvement in cognitive function.PMID:37735124 | DOI:10.31083/j.jin2205123
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Jinling Yin Yang Liu Wangang Lyu Yongzhao Fan Source Type: research

Identification of a TRP channel-related risk model for predicting prognosis and therapeutic effects of patients with hepatocellular carcinoma
CONCLUSIONS: We successfully established a highly accurate prognostic model for predicting overall survival and therapeutic effects using TRP channel-related genes.PMID:37733242 | DOI:10.1007/s00432-023-05394-7
Source: Cell Research - September 21, 2023 Category: Cytology Authors: Chong Pang Zhe Xu Jilong Han Fujun Li Hongyan Zhu Jiaqi Zhang Dong Wang Xundi Xu Source Type: research

Featured Health IT Job: Staff Nurse III – Information Technology at Natividad
We like to regularly feature a healthcare IT job that might be of interest to readers. Today, we’re featuring the Staff Nurse III – Information Technology at Natividad position that was recently posted on Healthcare IT Central. This position was posted by Natividad and is in Salinas, California. Here’s a description of the position: Inspiring Healthy Lives Through Community At Natividad, our dedication to the people of Monterey County is at the heart of everything we do—from the health care services we provide to the specialized programs we promote. This commitment to our community spans more than 130 ...
Source: EMR and HIPAA - September 20, 2023 Category: Information Technology Authors: Health IT Jobs Tags: Career and Jobs Healthcare IT Health IT Jobs Healthcare IT Jobs Information Technology Jobs Job Seekers Natividad Jobs Staff Nurse III Source Type: blogs

Learning to drive with neurological conditions: profile of users of an adapted driver training program and cognitive factors associated with success
CONCLUSION: These results suggest that approximately half of the persons enrolled in a driver training program designed for learners with neurological conditions, obtain a driver's license; and that attention, and to a lesser extent executive functioning and working memory, are related to driving program success.IMPLICATIONS FOR REHABILITATIONIn individual with neurological conditions, learning how to drive can be challenging.An adapted driver training program, involving collaboration between driving instructors and healthcare professionals, simplification of theoretical learning, and increasing driving practice opportunit...
Source: Disability and Rehabilitation - September 20, 2023 Category: Rehabilitation Authors: Adam Fahmi Mathieu Garon Alexandra Ribon-Demars Laurie Dubois Martin Caouette Marie- Ève Lamontagne Simon Beaulieu-Bonneau Source Type: research

Standardized circuit class group training versus individualized goal-directed group training to improve upper limb function in stroke survivors during in-patient rehabilitation: a pragmatic trial
CONCLUSIONS: A standardized training could reduce the mental workload for therapists, but patients seemed less engaged. A combination of both might be most beneficial.Trial registration: Dutch Trial Register: NL8844 and NL9471IMPLICATIONS FOR REHABILITATIONProviding a standardized training program after stroke reduces therapists' mental workload.Individualized goal-directed group training results in the best achievement of rehabilitation goals.A combination of standardized and individual training would use best of both intervention modalities.Patients should be involved in the co-creation developing process of training pro...
Source: Disability and Rehabilitation - September 20, 2023 Category: Rehabilitation Authors: S G Rozevink C M Beerepoot C K van der Sluis J M Hijmans Source Type: research

Behavior Management Training for Parents of Children with Preschool ADHD Based on Parent-Child Interactions: A Multicenter Randomized Controlled, Follow-Up Study
CONCLUSION: After continuous intervention for eight weeks, parents were able to help the children with preschool ADHD to improve their ADHD symptoms and emotional behavioral and social functioning significantly, and the efficacy was maintained at the four-month follow-up; the systemic-based parent training in behavior management (PTBM) is applicable to the treatment of preschool ADHD and is worth promoting.PMID:37727252 | PMC:PMC10506873 | DOI:10.1155/2023/3735634
Source: Behavioural Neurology - September 20, 2023 Category: Neurology Authors: Min Feng Juncai Xu Mengyao Zhai Qiaorong Wu Kangkang Chu Liping Xie Rong Luo Huiping Li Qiong Xu Xiu Xu Xiaoyan Ke Source Type: research