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Condition: Hypertension
Nutrition: Sodium

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Total 202 results found since Jan 2013.

Cardiovascular benefits and safety of non-insulin medications used in the treatment of type 2 diabetes mellitus.
Authors: Yandrapalli S, Jolly G, Horblitt A, Sanaani A, Aronow WS Abstract Diabetes mellitus is a growing in exponential proportions. If the current growth trend continues, it may result in every third adult in the United States having diabetes mellitus by 2050, and every 10(th) adult worldwide. Type 2 diabetes mellitus (T2DM) confers a 2- to 3-fold increased risk of cardiovascular (CV) events compared with non-diabetic patients, and CV mortality is responsible for around 80% mortality in this population. Patients with T2DM can have other features of insulin resistance-metabolic syndrome like hypertension, lipid ab...
Source: Postgraduate Medicine - July 29, 2017 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Comparisons of cardiometabolic biomarkers, lifestyle behaviors, and dietary sodium and potassium intake in a representative sample of Korean adults with and without cardio-cerebrovascular diseases
Conclusion The cardiometabolic condition varied, with hypertensives having a higher prevalence for obesity, high blood pressure, and cholesterol; poorer adherence to the behavioral recommendations was also noted in cardio-cerebrovascular diseases. Such variations in cardiovascular risks would provide implications for addressing vulnerability across groups.
Source: Asian Nursing Research - August 17, 2017 Category: Nursing Source Type: research

Nutrient intake and urinary incontinence in Korean women: A propensity score ‐matched analysis from the Korea National Health and Nutrition Examination Survey data
ConclusionHigh carbohydrate intake seems to be significantly related to female urinary incontinence in the Korean population.
Source: International Journal of Urology - August 28, 2017 Category: Urology & Nephrology Authors: Jun Ho Lee, Hyo Serk Lee Tags: Original Article Source Type: research

Recent Insights into Pharmacologic Cardiovascular Risk Reduction in Type 2 Diabetes Mellitus
In conclusion, there is a growing literature which shows that the risk of cardiovascular outcomes can be reduced in most patients wi th diabetes, as outlined in this review.
Source: Cardiovascular Drugs and Therapy - September 4, 2017 Category: Cardiology Source Type: research

Former CDC chief Frieden to head $225m anti-heart disease initiative
Previous US Centers for Disease Control and Prevention director Dr. Tom Frieden said he will head Resolve, a new public health initiative focused on fighting heart disease and stroke which has already raised $225 million in backing from a handful of private philanthropies. The Bill & Melinda Gates Foundation, Bloomberg Philanthropies and the Chan Zuckerberg Initiative have joined in to fund the initiative. Resolve plans to invest in efforts to reduce trans-fats from restaurant menus, which follows up on Frieden’s 2006 efforts to ban trans-fats as the New York City health commissioner. The initiative will also look to...
Source: Mass Device - September 12, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Centers for Disease Control & Prevention (CDC) Source Type: news

Abstract 104: Cerebrovascular and Cognitive Dysfunction in DOCA-Salt Hypertension is Mediated by Perivascular Macrophages Session Title: Salt and Hypertension
Hypertension (HTN) and high-salt diets are important risk factors for stroke and dementia. DOCA-salt is a recognized model of HTN driven by sodium retention and brain renin-angiotensin system (RAS) activation. However, it is unknown whether essential mechanisms regulating the cerebral circulation are altered in DOCA-salt mice, and, if so, whether these alterations are associated with cognitive impairment. To this end, C57BL/6 mice were implanted with 50mg DOCA pellets SQ and received 0.9% NaCl drinking water for 3 weeks. Cerebral blood flow (CBF) was measured in the somatosensory cortex by laser-Doppler flowmetry through a...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Monica M Santisteban, Giuseppe Faraco, Gianfranco Racchumi, Josef Anrather, Costantino Iadecola Tags: Oral Abstract Presentations Source Type: research

Abstract 137: Sox6 Regulates Renin Expression During Juxtaglomerular Cell Expansion Session Title: Renin Angiotensin System II
Introduction: Hypertension, a common condition that affects 33% of the US population, is a major risk factor for heart disease and stroke. Treatments for hypertension are limited and there is a critical need to develop new therapies. The Renin Angiotensin Aldosterone System (RAAS) plays a key role in regulating blood pressure, and renin controls its rate-limiting step. In adults, renin is produced and stored by renal Juxtaglomerular (JG) cells. During sodium restriction and other pathophysiological stresses that require an increase in renin expression and release, the adult kidney increases the number of cells expressing r...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Jason D Foss, Liang Xiao, Kandi D Horton, Mohammad Saleem, Conrad P Hodgkinson, David G Harrison, Jose A Gomez Tags: Oral Abstract Presentations Source Type: research

Abstract P445: Sympathetic and Renal Mechanisms of Age-related Hypertension Session Title: Hypertension and Aging and Cerebrovascular Disease and Stroke
Hypothesis: Sympathoexcitation and sodium retention contribute to age-related hypertension (HTN).Methods: Three, 8, and 16 month old male SD rats underwent an IV volume expansion (VE; 5% BW) and MAP, HR, urine output and paraventricular nucleus (PVN) neuronal activation (c-Fos expression) were assessed. In separate groups of rats fed a 21 day normal (NS; 0.6% NaCl) or high salt (HS; 4% NaCl) diet, measures of 1) ex vivo afferent renal nerve (ARN) activity (norepinephrine (NE)-evoked substance P release) or 2) MAP, HR, NCC activity (ΔUNaV to IV HCTZ, 2mg/kg) and sympathetic tone (plasma and renal NE content, ΔMAP to IV he...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Richard D Wainford, Alissa A Frame Tags: Poster Abstract Presentations Source Type: research

Effects of dopamine receptor antagonist antipsychotic therapy on blood pressure
ConclusionBased upon this review, individuals on antipsychotic agents, particularly clozapine, should be routinely monitored for hypertension, and addition of antihypertensive agents such as angiotensin‐converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) is indicated if hypertension occurs. Dopamine receptors play a role in blood pressure regulation. The objective of this review is to investigate the association between dopamine antagonist use and hypertension. Based upon this review, individuals on antipsychotic agents, particularly clozapine, should have blood pressure routinely monitored, and a...
Source: Journal of Clinical Pharmacy and Therapeutics - November 8, 2017 Category: Drugs & Pharmacology Authors: N. H. Gonsai, V. H. Amin, C. G. Mendpara, R. Speth, G. M. Hale Tags: REVIEW ARTICLE Source Type: research

Benefit and risk assessment of increasing potassium intake by replacement of sodium chloride with potassium chloride in industrial food products in Norway.
In conclusion, the number of Norwegians facing increased risk is far greater than the number likely to benefit from this replacement of sodium with potassium in industrially produced food. PMID: 29175183 [PubMed - as supplied by publisher]
Source: Food and Chemical Toxicology - November 22, 2017 Category: Food Science Authors: Steffensen IL, Frølich W, Dahl KH, Iversen PO, Lyche JL, Lillegaard ITL, Alexander J Tags: Food Chem Toxicol Source Type: research

Taste perception and diet in people of Chinese ancestry.
CONCLUSIONS: There was a salty-sour confusion among Singaporean Chinese unlike the bitter-sour confusion reported for Caucasians. Most sodium came from sauces and was added during food preparation. In programs to address sodium: potassium ratio excess among Chinese prone to hypertension and stroke, sour as well as salty taste may need to be considered. PMID: 29384339 [PubMed - in process]
Source: Asia Pacific Journal of Clinical Nutrition - February 2, 2018 Category: Nutrition Authors: Leong CS, Forde CG, Tey SL, Henry CJ Tags: Asia Pac J Clin Nutr Source Type: research

An exaggerated blood pressure response to exercise is associated with the dietary sodium, potassium, and antioxidant vitamin intake in normotensive subjects.
CONCLUSIONS: These results suggest that an exaggerated SBP response to exercise was associated with the dietary sodium, potassium, and antioxidant vitamin intake in normotensive subjects. PMID: 29553836 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Hypertension - March 19, 2018 Category: Cardiology Authors: Michishita R, Ohta M, Ikeda M, Jiang Y, Yamato H Tags: Clin Exp Hypertens Source Type: research

Summary: International Kidney Cancer Symposium
Conclusions:  Ideal ischemia time is 20-25 minutes or less improves short and long term renal function. >25 minutes carried 5 year risk of new onset stage 4 CKD No differences on GFR for cold vs. warm ischemia times Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.  No ischemia preserves renal function better than warm. Longer cold ischemia times were equivalent to shorter warm ischemia times. Quality and quantity of the remaining kidney is associated with ultimate renal function. Robotics in RCC Surgery Gennady Bratslavsky, MD The opening question ...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news

Enhanced expression of the Epithelial Sodium Channel in neutrophils from hypertensive patients
Publication date: Available online 10 November 2018Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Erika Reus-Chavarría, Ivette Martínez-Vieyra, Cristina Salinas-Nolasco, Araceli Evangelina Chávez-Piña, Juan Vicente Méndez-Méndez, Edgar Oliver López-Villegas, Alejandro Sosa-Peinado, Doris CerecedoAbstractHypertension (HTN), i.e. abnormally high blood pressure, is a major risk factor for heart attack, stroke, and kidney failure. The Epithelial Sodium Channel (ENaC), one of the main transporters regulates blood pressure by tightly controlling the sodium reabsorption along the nephron. Recently, we...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - November 12, 2018 Category: Biochemistry Source Type: research

Clinical implications of cardiovascular outcome trials in type  2 diabetes.
Clinical implications of cardiovascular outcome trials in type 2 diabetes. Herz. 2019 Feb 25;: Authors: Mellbin LG, Wang A, Rydén L Abstract Cardiovascular disease (CVD) is the main reason for premature death in patients with type 2 diabetes. Hyperglycemia, the hallmark of diabetes, has long been considered the link between diabetes and CVD, and many trials focused on preventing CVD manifestations by means of tight glucose control. However, diabetes is a multifactorial disease in which, e. g., insulin resistance, endothelial dysfunction, and factors such as hypertension and dyslipidemia contrib...
Source: Herz - February 27, 2019 Category: Cardiology Tags: Herz Source Type: research