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Condition: Hemorrhagic Stroke
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Total 499 results found since Jan 2013.

Featured Review: Endovascular thrombectomy for acute ischaemic stroke
In thisrecently published Cochrane review, authors explored the effects of treating acute ischaemic stroke with endovascular thrombectomy and intra-arterial interventions.First author Melinda Roaldsen said: " This review of endovascular thrombectomy for acute ischaemic stroke strongly reinforces the efficacy and safety of endovascular interventions. Endovascular thrombectomy is a treatment modality in rapid development and continues to gain significance in acute stroke care. This review finds high evidence that endovascular thrombectomy improves functional and neurological outcomes without increasing intracerebral haemorrh...
Source: Cochrane News and Events - May 11, 2021 Category: Information Technology Authors: Rachel Klabunde Source Type: news

Featured Review: Endovascular thrombectomy and intra ‐arterial interventions for acute ischaemic stroke
In thisrecently published Cochrane review, authors explored the effects of treating acute ischaemic stroke with endovascular thrombectomy and intra-arterial interventions.First author Melinda Roaldsen said: " This review of endovascular thrombectomy for acute ischaemic stroke strongly reinforces the efficacy and safety of endovascular interventions. Endovascular thrombectomy is a treatment modality in rapid development and continues to gain significance in acute stroke care. This review finds high evidence that endovascular thrombectomy improves functional and neurological outcomes without increasing intracerebral haemorrh...
Source: Cochrane News and Events - May 11, 2021 Category: Information Technology Authors: Rachel Klabunde Source Type: news

Acute symptomatic seizures and hippocampal sclerosis: the major contributor for post-stroke epilepsy?
AbstractObjectiveHippocampal sclerosis (HS) is a prominent biomarker of epilepsy. If acquired later in life, it usually occurs in the context of degenerative or acute inflammatory-infectious disease. Conversely, acute symptomatic seizures (ASS) are considered a risk factor for developing post-stroke epilepsy, but other factors remain unrecognized. Here, we hypothesize that silent hippocampal injury contributes to the development of post-stroke epilepsy.MethodsWe performed a retrospective observational study of patients hospitalized between 1/2007 and 12/2018 with an acute stroke in the Stroke Center of the Geneva Universit...
Source: Journal of Neurology - July 7, 2022 Category: Neurology Source Type: research

Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial
This study is registered, number ISRCTN99414122. Findings Between July 20, 2001, and Oct 14, 2013, we enrolled 4011 patients. Mean blood pressure was 167 (SD 19) mm Hg/90 (13) mm Hg at baseline (median 26 h [16–37] after stroke onset), and was significantly reduced on day 1 in 2000 patients allocated to glyceryl trinitrate compared with 2011 controls (difference −7·0 [95% CI −8·5 to −5·6] mm Hg/–3·5 [–4·4 to −2·6] mm Hg; both p<0·0001), and on day 7 in 1053 patients allocated to continue antihypertensive drugs compared with 1044 patients randomised to stop them (difference −9·5 [95% CI −11...
Source: The Lancet - February 13, 2015 Category: Journals (General) Source Type: research

"MOONSTROKE": Lunar patterns of stroke occurrence combined with circadian and seasonal rhythmicity-A hospital based study.
Abstract Both time of the day and season have been shown to have a significant effect on stroke incidence. In contrast, the role played by the moon has been little studied. We aimed to investigate the potential association of the lunar phase with the incidence of stroke subtypes [intracerebral hemorrhage (ICH), transient ischemic attack (TIA) and ischemic stroke (IS)], adjusted by circadian and seasonal variations. Consecutive stroke admissions to the Royal Melbourne Hospital (RMH) were analyzed from 2004-2011. Of 6252 patients, 4085 (65.3%) had confirmed dates and hour of the day. Of these, 632 (15.5%) had ICH, 6...
Source: Chronobiology International - July 14, 2015 Category: Biology Authors: Mao Y, Schnytzer Y, Busija L, Churilov L, Davis S, Yan B Tags: Chronobiol Int Source Type: research

Risk of stroke in patients with newly diagnosed multiple myeloma: a retrospective cohort study
This study includes consecutive patients 20 years and older who were newly diagnosed with symptomatic multiple myeloma at Taipei Veterans General Hospital, a tertiary medical center, between January 1, 2002 and December 31, 2014. The primary outcome was stroke development. Patients with head injuries, brain tumors, brain parenchymal invasions, or antecedent malignancies were excluded. Hazard ratios (HRs) of stroke risk factors for multiple myeloma patients were estimated by Cox proportional regression analysis. Overall, 395 patients with a median age of 70 years were investigated. In the median follow‐up period of 18 ...
Source: Hematological Oncology - August 21, 2016 Category: Hematology Authors: Gin ‐Yi Lee, Yu‐Ting Lee, Chiu‐Mei Yeh, Pei Hsu, Ting‐Wei Lin, Jyh‐Pyng Gau, Yuan‐Bin Yu, Liang‐Tsai Hsiao, Cheng‐Hwai Tzeng, Tzeon‐Jye Chiou, Jin‐Hwang Liu, Yao‐Chung Liu, Chia‐Jen Liu Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Secondary prevention treatment after acute stroke in older South Asian, Chinese and other Canadians: a retrospective data analysis.
Abstract BACKGROUND: Little is known about whether there are differences in medication use between older patients of Chinese descent, those of South Asian descent and other Canadian patients after acute ischemic or primary intracerebral hemorrhagic stroke. The aim of this population-based study was to evaluate potential ethnic differences in secondary prevention pharmacotherapy after acute stroke. METHODS: Using health administrative data, we conducted a retrospective analysis of all patients aged 66 years or more admitted to hospital with acute stroke in Ontario (1997-2011) and British Columbia (1997-2009). ...
Source: cmaj - September 11, 2017 Category: General Medicine Authors: Khan NA, McAlister FA, Pilote L, Palepu A, Quan H, Hill MD, Fang J, Kapral MK Tags: CMAJ Open Source Type: research

Predictors of mortality and disability in stroke-associated pneumonia
AbstractWhilst stroke-associated pneumonia (SAP) is common and associated with poor outcomes, less is known about the determinants of these adverse clinical outcomes in SAP. To identify the factors that influence mortality and morbidity in SAP. Data for patients with SAP (n = 854) were extracted from a regional Hospital Stroke Register in Norfolk, UK (2003–2015). SAP was defined as pneumonia occurring within 7 days of admission by the treating clinicians. Mutlivariable regression models were constructed to assess factors influencing survival and the level of di sability at discharge using modified Rankin Scale [mRS]...
Source: Acta Neurologica Belgica - April 28, 2019 Category: Neurology Source Type: research

Safety and efficacy of co-careldopa as an add-on therapy to occupational and physical therapy in patients after stroke (DARS): a randomised, double-blind, placebo-controlled trial
Publication date: June 2019Source: The Lancet Neurology, Volume 18, Issue 6Author(s): Gary A Ford, Bipin B Bhakta, Alastair Cozens, Suzanne Hartley, Ivana Holloway, David Meads, John Pearn, Sharon Ruddock, Catherine M Sackley, Eirini-Christina Saloniki, Gillian Santorelli, Marion F Walker, Amanda J FarrinSummaryBackgroundDopamine is a key modulator of striatal function and learning and might improve motor recovery after stroke. Previous small trials of dopamine agonists after stroke provide equivocal evidence of effectiveness on improving motor recovery. We aimed to assess the safety and efficacy of co-careldopa plus routi...
Source: The Lancet Neurology - May 22, 2019 Category: Neurology Source Type: research

Long-term exposure to air pollution and stroke incidence: A Danish Nurse cohort study.
Abstract Ambient air pollution has been linked to stroke, but few studies have examined in detail stroke subtypes and confounding by road traffic noise, which was recently associated with stroke. Here we examined the association between long-term exposure to air pollution and incidence of stroke (overall, ischemic, hemorrhagic), adjusting for road traffic noise. In a nationwide Danish Nurse Cohort consisting of 23,423 nurses, recruited in 1993 or 1999, we identified 1,078 incident cases of stroke (944 ischemic and 134 hemorrhagic) up to December 31, 2014, defined as first-ever hospital contact. The full residentia...
Source: Environment International - June 23, 2020 Category: Environmental Health Authors: Amini H, Dehlendorff C, Lim YH, Mehta A, Jørgensen JT, Mortensen LH, Westendorp R, Hoffmann B, Loft S, Cole-Hunter T, Bräuner EV, Ketzel M, Hertel O, Brandt J, Solvang Jensen S, Christensen JH, Geels C, Frohn LM, Backalarz C, Simonsen MK, Andersen ZJ Tags: Environ Int Source Type: research

IJERPH, Vol. 18, Pages 7696: Multidisciplinary Care after Acute Care for Stroke: A Prospective Comparison between a Multidisciplinary Post-Acute Care Group and a Standard Group Matched by Propensity Score
ng Hon-Yi Shi In this large-scale prospective cohort study, a propensity score matching method was applied in a natural experimental design to investigate how post-acute care (PAC) after stroke affects functional status and to identify predictors of functional status. The main objective of this study was to examine longitudinal changes in various measures of functional status in stroke patients and predictors of scores for these measures before and after PAC. A group of patients who had received PAC for stroke at one of two medical centers (PAC group, n = 273) was compared with a group who had received standard care ...
Source: International Journal of Environmental Research and Public Health - July 20, 2021 Category: Environmental Health Authors: Chong-Chi Chiu Hsiu-Fen Lin Ching-Huang Lin Hong-Tai Chang Hong-Hsi Hsien Kuo-Wei Hung Sheng-Li Tung Hon-Yi Shi Tags: Article Source Type: research

Fabry-Stroke Italian Registry (FSIR): a nationwide, prospective, observational study about incidence and characteristics of Fabry-related stroke in young-adults. Presentation of the study protocol
DiscussionThe potential implications of this study are as follows: (i) to add information about the yield of systematic screening for Fabry disease in a prospective large cohort of acute cerebrovascular patients; (ii) to deepen knowledge of clinical, pathophysiological, and prognostic characteristics of Fabry-related stroke.
Source: Neurological Sciences - October 5, 2021 Category: Neurology Source Type: research

Improving the one-year mortality of stroke patients: an 18-year observation in a teaching hospital.
This study determined the one-year survival rate and prognostic factors of hospitalized hemorrhagic and ischemic stroke patients from 1991 to 2008 in a teaching hospital in Taiwan. We also evaluated the improvements in the one-year mortality after stroke during an 18-year study period. Patients admitted for cerebral hemorrhage (n = 3,678) and cerebral infarction (n = 16,010), identified from an in-patient electronic database, were linked to the National Death Registry of Taiwan. Actuarial analysis was used to determine the one-year survival rates, and Cox proportional hazard regression model was used to investigate the pre...
Source: The Tohoku Journal of Experimental Medicine - February 8, 2014 Category: Research Authors: Chen HF, Li CY, Lee SP, Kwok YT, Chu YT Tags: Tohoku J Exp Med Source Type: research

CARES (Changing and Advancing Risk factor control through Educations after Stroke): A Pilot Trial of a Transitions in Care Post-discharge Telephone Intervention for Stroke Patients (S13.006)
OBJECTIVE: The purpose of study is to test the feasibility and effectiveness of a telephonic post-discharge intervention designed to improve access to care, reinforce self-management skills, improve health literacy, and screen for complications in a government-run safety net system. BACKGROUND: In the United States, risk factor control after stroke is poor, particularly among socio-economically disadvantaged populations with poor access to care. The immediate post-discharge period is a vulnerable time for stroke patients, given their risk of recurrent stroke, worsening symptoms, complications, and need for medication titra...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hudson, L., Corrales, M., Moreno, L., Valle, N., Razmara, A., Dutta, T., Ramirez-Gomez, L., Towfighi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors Source Type: research

Head Position in Stroke Trial (HeadPoST) – sitting-up vs lying-flat positioning of patients with acute stroke: study protocol for a cluster randomised controlled trial
DiscussionHeadPoST is a large international clinical trial in which we will rigorously evaluate the effects of different head positioning in patients with acute stroke.Trial registrationClinicalTrials.gov identifier: NCT02162017 (date of registration: 27 April 2014); ANZCTR identifier: ACTRN12614000483651 (date of registration: 9 May 2014). Protocol version and date: version 2.2, 19 June 2014.
Source: Trials - June 5, 2015 Category: Journals (General) Authors: Paula Muñoz-VenturelliHisatomi ArimaPablo LavadosAlejandro BrunserBin PengLiying CuiLily SongLaurent BillotElizabeth BoadenMaree HackettStephane HeritierStephen JanSandy MiddletonVerónica OlavarríaJoyce LimRichard LindleyEmma HeeleyThompson RobinsonOct Source Type: research