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Condition: Reflex Sympathetic Dystrophy

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Total 1447 results found since Jan 2013.

Potential specific immunological indicators for stroke associated infection are partly modulated by sympathetic pathway activation.
CONCLUSION: IL-6, IL-10 and HLA-DR are good candidate biomarkers for SAI. The activation of the sympathetic pathway could partly account for the specific immunological alterations found in SAI patients including HLA-DR decrease and IL-10 increase, which both could be reversed by propranolol. However, the mechanism underlying IL-6 increase still needs further exploration. PMID: 27409177 [PubMed - as supplied by publisher]
Source: Oncotarget - July 15, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Slacklining and stroke: A rehabilitation case study considering balance and lower limb weakness.
Authors: Gabel CP, Rando N, Melloh M Abstract To ascertain the effectiveness of slacklining as a supplementary therapy for elderly stroke patients who are functionally non-progressing. This case study involved an 18-mo prospective observation of the management of an 87-year-old female stroke-patient of the left hemisphere with reduced balance, reduced lower limb muscular activation, hypertonia, and concurrent postural deficits. This entailed the initial acute care phase through to discharge to home and 18-mo final status in her original independent living setting. The introduction of slacklining as an adjunct thera...
Source: World Journal of Orthopaedics - September 15, 2016 Category: Orthopaedics Tags: World J Orthop Source Type: research

Stretch-reflex threshold modulation during active elbow movements in post-stroke survivors with spasticity.
CONCLUSIONS: Spasticity thresholds measured at rest were modulated during active movement. Arm motor impairments were related to the ability to modulate SR thresholds between the two states rather than to passive-state values. SIGNIFICANCE: Relationship between spasticity and movement disorders may be explained by deficits in SR threshold range of regulation and modifiability, representing a measure of stroke-related sensorimotor deficits. PMID: 28826019 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - August 3, 2017 Category: Neurology Authors: Turpin NA, Feldman AG, Levin MF Tags: Clin Neurophysiol Source Type: research

Heart Rate Variability modifications induced by high doses of IncobotulinumtoxinA and OnabotulinumtoxinA in hemiplegic chronic stroke patients: A single blind randomized controlled, crossover pilot study.
CONCLUSIONS: Our data show that high doses (>600 U) of incobotulinumtoxinA and onabotulinumtoxinA do not influence the cardiovascular activity of the autonomic nervous system in chronic hemiplegic spastic stroke survivors. PMID: 28877510 [PubMed - as supplied by publisher]
Source: Toxicon - September 3, 2017 Category: Toxicology Authors: Baricich A, Grana E, Carda S, Santamato A, Molinari C, Cisari C, Invernizzi M Tags: Toxicon Source Type: research

Neural Vascular Mechanism for the Cerebral Blood Flow Autoregulation after Hemorrhagic Stroke.
Abstract During the initial stages of hemorrhagic stroke, including intracerebral hemorrhage and subarachnoid hemorrhage, the reflex mechanisms are activated to protect cerebral perfusion, but secondary dysfunction of cerebral flow autoregulation will eventually reduce global cerebral blood flow and the delivery of metabolic substrates, leading to generalized cerebral ischemia, hypoxia, and ultimately, neuronal cell death. Cerebral blood flow is controlled by various regulatory mechanisms, including prevailing arterial pressure, intracranial pressure, arterial blood gases, neural activity, and metabolic demand. Ev...
Source: Neural Plasticity - November 8, 2017 Category: Neurology Authors: Xiao M, Li Q, Feng H, Zhang L, Chen Y Tags: Neural Plast Source Type: research

Research Articles Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke
Stroke induces a multiphasic systemic immune response, but the consequences of this response on atherosclerosis—a major source of recurrent vascular events—have not been thoroughly investigated. We show that stroke exacerbates atheroprogression via alarmin-mediated propagation of vascular inflammation. The prototypic brain-released alarmin high-mobility group box 1 protein induced monocyte and endothelial activation via the receptor for advanced glycation end products (RAGE)–signaling cascade and increased plaque load and vulnerability. Recruitment of activated monocytes via the CC-chemokine ligand 2&ndas...
Source: Science Translational Medicine - March 14, 2018 Category: Biomedical Science Authors: Roth, S., Singh, V., Tiedt, S., Schindler, L., Huber, G., Geerlof, A., Antoine, D. J., Anfray, A., Orset, C., Gauberti, M., Fournier, A., Holdt, L. M., Harris, H. E., Engelhardt, B., Bianchi, M. E., Vivien, D., Haffner, C., Bernhagen, J., Dichgans, M., Li Tags: Research Articles Source Type: research

Adrenal hormones and circulating leukocyte subtypes in stroke patients treated with reperfusion therapy.
Abstract Ischemic stroke sets in motion a dialogue between the central nervous and the immune systems that includes the sympathetic/adrenal system. We investigated the course of immune cells and adrenocortical and adrenomedullary effectors in a cohort of 51 patients with acute stroke receiving reperfusion therapy (intravenous alteplase or mechanical thrombectomy) and its correlation with stroke outcomes and infarct growth. Cortisol increased rapidly and fleetingly after stroke, but 39% of patients who had larger infarctions on admission showed a positive delta cortisol at day 1. It was associated with enhanced inf...
Source: Brain, Behavior, and Immunity - March 13, 2018 Category: Neurology Authors: Miró-Mur F, Laredo C, Renú A, Rudilosso S, Zhao Y, Amaro S, Llull L, Urra X, Planas AM, Chamorro Á Tags: Brain Behav Immun Source Type: research

Unilateral wrist extension training after stroke improves strength and neural plasticity in both arms.
This study shows that high-intensity training with the neurologically less affected "non-paretic" arm can improve strength bilaterally and alter both spinal and cortical plasticity. The extent to which this plasticity can be enhanced or functionally exploited remains to be examined. PMID: 29730752 [PubMed - as supplied by publisher]
Source: Experimental Brain Research - May 5, 2018 Category: Neuroscience Authors: Sun Y, Ledwell NMH, Boyd LA, Zehr EP Tags: Exp Brain Res Source Type: research

Change in Reciprocal Inhibition of the Forearm with Motor Imagery among Patients with Chronic Stroke.
In conclusion, mental practice with MI may induce plastic change in spinal reciprocal inhibitory circuits in patients with stroke. PMID: 29853844 [PubMed - in process]
Source: Neural Plasticity - June 6, 2018 Category: Neurology Authors: Kawakami M, Okuyama K, Takahashi Y, Hiramoto M, Nishimura A, Ushiba J, Fujiwara T, Liu M Tags: Neural Plast Source Type: research

Horner syndrome in ipsilateral lenticulostriate stroke: a novel localization for a classic stroke syndrome
AbstractHorner ’s syndrome has important localizing and etiological value in acute ischemic stroke. In a prospective series of consecutive acute ischemic stroke patients, we identified three patients with Horner’s syndrome and contralateral hemiparesis due to ipsilateral small deep infarction in the middle cer ebral artery territory (lenticulostriate arteries). Lacunar stroke was the most likely stroke mechanism in all three patients. This observation might suggest the existence of an uncrossed cortico-hypothalamic sympathetic pathway passing through the basal ganglia and modulating oculosympathetic funct ion.
Source: Clinical Autonomic Research - July 10, 2018 Category: Research Source Type: research

The effect of unilateral stroke on autonomic function in the term newborn.
CONCLUSION: Based on these findings, it is difficult to reconcile the functional topography of the central autonomic system in term newborns with that currently proposed for the normal mature brain. Further investigation is clearly needed. PMID: 30712058 [PubMed - as supplied by publisher]
Source: Pediatric Research - February 2, 2019 Category: Pediatrics Authors: Reich DA, Govindan RB, Whitehead MT, Wang J, Chang T, Kota S, du Plessis AJ Tags: Pediatr Res Source Type: research

Possible Contributions of Ipsilateral Pathways From the Contralesional Motor Cortex to the Voluntary Contraction of the Spastic Elbow Flexors in Stroke Survivors: A TMS Study
Conclusions These results provide novel evidence that ipsilateral projections are not likely to contribute to strength but are correlated to spasticity of spastic-paretic elbow flexors after stroke.
Source: American Journal of Physical Medicine and Rehabilitation - June 20, 2019 Category: Rehabilitation Tags: Original Research Articles Source Type: research

Acupuncture alleviates spinal hyperreflexia and motor dysfunction in post-ischemic stroke rats with spastic hypertonia via KCC2-mediated spinal GABA < sub > A < /sub > activation
Exp Neurol. 2022 Mar 1:114027. doi: 10.1016/j.expneurol.2022.114027. Online ahead of print.ABSTRACTThe majority of patients simultaneously develop motor dysfunction and spastic hypertonia after ischemic strokes, which can be associated with an increasing trend in motor impairments, seriously impeding the rehabilitation process. Evidence suggests that some deficits in the KCC2 expression in the spinal cord along with maladaptive endogenous plasticity via GABAA receptors are often involved in the pathology of spastic hypertonia after a stroke. In this respect, acupuncture has been commonly used in clinical settings for post-...
Source: Experimental Neurology - March 4, 2022 Category: Neurology Authors: Jie-Dan Mu Liang-Xiao Ma Zhou Zhang Wen-Yan Yu Tian-Yi Sun Xu Qian Yuan Tian Jun-Xiang Wang Source Type: research

Artificial intelligence for early stroke diagnosis in acute vestibular syndrome
ConclusionAI can accurately diagnose a vestibular stroke by using unprocessed vHIT time series. The quantification of eye- and head movements with the use of machine learning and AI can serve in the future for an automated diagnosis in ED patients with acute dizziness. The application of different neural network architectures can potentially further improve performance and enable direct inference from raw video recordings.
Source: Frontiers in Neurology - September 8, 2022 Category: Neurology Source Type: research