Filtered By:
Condition: Metabolic Syndrome
Nutrition: Diets

This page shows you your search results in order of relevance. This is page number 4.

Order by Relevance | Date

Total 70 results found since Jan 2013.

Use of a bioengineered antioxidant in mouse models of metabolic syndrome.
Conclusions: PEG-HCC can improve some parameters of disease in these models and this may be due to a resulting increase in peripheral insulin sensitivity. However, additional studies are needed to elucidate how PEG-HCCs are producing these effects. PMID: 31937152 [PubMed - as supplied by publisher]
Source: Expert Opinion on Investigational Drugs - January 17, 2020 Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research

The contribution of chymase-dependent formation of AngII to cardiac dysfunction in metabolic syndrome of young rats: roles of fructose and EETs.
In conclusions, HFD-driven adverse chymase/AngII/AT1R/Nox/superoxide signaling in young rats was prevented by inhibition of sEH via at least in part, an EET-mediated stabilization of mast cells, highlighting chymase and sEH as therapeutic targets during treatment of MetS. PMID: 32167781 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 12, 2020 Category: Physiology Authors: Froogh G, Kandhi S, Duvvi R, Le Y, Weng Z, Alruwaili N, Ashe JO, Sun D, Huang A Tags: Am J Physiol Heart Circ Physiol Source Type: research

Lead Anti-obesity Compounds from Nature.
Conclusion-Consumption of diets comprising high amounts of active anti-obesity natural compounds is a promising strategy for the suppression of lipid accumulation and adipogenesis in obese individuals. PMID: 32364084 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - May 2, 2020 Category: Endocrinology Authors: Dahiya V, Vasudeva N, Sharma S, Kumar A, Rowley D Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

Association of a genetic variant in the AKT gene locus and cardiovascular risk factors.
Authors: Kermanshahi F, Ghazizadeh H, Hussein NA, Amerizadeh F, Samadi S, Tayefi M, Kamel Khodabandeh A, Moohebati M, Ebrahimi M, Esmaily H, Sahebi R, Abdulkarimi R, Mousavi SAR, Ferns GA, Avan A, Ghayour-Mobarhan M Abstract Cardiovascular disease (CVDs) is the leading cause of morbidity and death worldwide. Most genetic variants could be identified by several genome-wide-association-studies (GWAS), including within genes encoding proteins involved in the AKT/PI3K pathways that are related with an increased risk of metabolic syndrome and CVDs. Therefore, due to the importance of genetic variants in the prognosis of...
Source: Cellular and Molecular Biology - June 18, 2020 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

Mediterranean diet adherence and metabolic syndrome in US adolescents.
Authors: Kim RJ, Lopez R, Snair M, Tang A Abstract The Mediterranean diet (MD) has been found to lower the risk of heart disease, stroke, and diabetes in adults. Little is known about its acceptance and relationship to cardiovascular risk markers in US adolescents. Using data from the National Health and Nutrition Examination Survey, years 2007-2014, we performed a cross-sectional analysis of adherence to the Mediterranean diet among a representative sample of US adolescents (n = 4223), factors that influence adherence, and whether adherence is associated with cardiometabolic risk factors including metabolic sy...
Source: International Journal of Food Sciences and Nutrition - October 30, 2020 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research

Recent Insights on the Role of PPAR- β/δ in Neuroinflammation and Neurodegeneration, and Its Potential Target for Therapy
AbstractPeroxisome proliferator-activated receptor (PPAR) β/δ belongs to the family of hormone and lipid-activated nuclear receptors, which are involved in metabolism of long-chain fatty acids, cholesterol, and sphingolipids. Similar to PPAR-α and PPAR-γ, PPAR-β/δ also acts as a transcription factor activated by dietary lipids and endogenous ligands, such as long-chain saturated and polyunsaturated fatty acids, and selected lipid metabolic products, such as eicosanoids, leukotrienes, lipoxins, and hydroxyeicosatetraenoic acids. Together with other PPARs, PPAR-β/δ displays transcriptional activity through interactio...
Source: NeuroMolecular Medicine - November 18, 2020 Category: Neurology Source Type: research

Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut microbiota and attenuating intestinal barrier injury
Biomed Pharmacother. 2021 Feb 27;138:111441. doi: 10.1016/j.biopha.2021.111441. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) is a complex, multifactorial disease which lead to an increased risk of cardiovascular disease, type 2 diabetes, and stroke. However, selective, and potent drugs for the treatment of MetS are still lacking. Previous studies have found that Akebia saponin D (ASD) has beneficial effects on metabolic diseases such as obesity, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD). Therefore, our study was designed to determine the effect and mechanism of action of ASD against MetS in ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - March 2, 2021 Category: Drugs & Pharmacology Authors: Song Yang Ting Hu He Liu Ya-Li Lv Wen Zhang Han Li Lingling Xuan Li-Li Gong Li-Hong Liu Source Type: research

Pro-Neurotensin/Neuromedin N and Risk of Incident Metabolic Syndrome and Diabetes Mellitus in the REGARDS Cohort
CONCLUSIONS: Pro-NT/NMN was associated with MetS and two components, dysglycemia and low HDL, likely explained by insulin resistance.PMID:34013344 | DOI:10.1210/clinem/dgab355
Source: The Journal of Clinical Endocrinology and Metabolism - May 20, 2021 Category: Endocrinology Authors: Charles D Nicoli April P Carson Timothy B Plante D Leann Long Leslie A McClure Janin Schulte Mary Cushman Source Type: research

Developmental Origins of Metaflammation; A Bridge to the Future Between the DOHaD Theory and Evolutionary Biology
Metabolic syndrome refers to obesity-associated metabolic disorders that increase the risk of type 2 diabetes, coronary diseases, stroke, and other disabilities. Environmental imbalance during the early developmental period affects health and increases susceptibility to non-communicable diseases, including metabolic syndrome, in later life; therefore, the Developmental Origins of Health and Disease (DOHaD) theory was established. According to the DOHaD theory, the hypothesis of the energy-saving ‘Thrifty Phenotype’ in undernourished fetuses is one of the well-accepted schemes as a risk of developing metabolic syndrome....
Source: Frontiers in Endocrinology - February 3, 2022 Category: Endocrinology Source Type: research

Meal Timing, Meal Frequency and Metabolic Syndrome
Nutrients. 2022 Apr 21;14(9):1719. doi: 10.3390/nu14091719.ABSTRACTIndividuals with metabolic syndrome have increased risk for developing health conditions, including cardiovascular diseases and stroke. Modifiable risk factors, such as exercise and diet, are key components in the prevention and control of metabolic syndrome. Specifically, dietary patterns and habits are extremely successful in controlling more than one of the metabolic syndrome risk factors. Meal timing and frequency have been associated with type 2 diabetes, cardiovascular diseases, and other chronic conditions. However, there is limited evidence linking ...
Source: Cancer Control - May 14, 2022 Category: Cancer & Oncology Authors: Fatema Alkhulaifi Charles Darkoh Source Type: research

A systematic review of randomized clinical trials on the efficacy and safety of pitavastatin
Conclusion The FDA proven indications of pitavastatin are primary dyslipidemia and mixed dyslipidemia as adjunctive therapy to dietary changes to lower total cholesterol, LDL-C, apolipoprotein B (Apo B), triglycerides (TG), and to increase HDL-C. Pitavastatin might be suitable for subjects with diabetes, ACS (reduced revascularization), metabolic syndrome, CKD, HIV, and subjects with low levels of HDL-C. We highly recommend rational individualization for the selection of statin.PMID:35642121 | DOI:10.2174/2772432817666220531115314
Source: Pharmacological Reviews - June 1, 2022 Category: Drugs & Pharmacology Authors: Asim Ahmed Elnour Judit Don Azza Ramadan Adel Sadeq Abdulla Al Amoodi Kishore Gnana Sam Nadia Al Mazrouei Mohamed A Baraka Farah Hamad Farah Maisoun Alkaabi Source Type: research

A Potential Strategy for Atherosclerosis Prevention in Modernizing China — Hyperhomocysteinemia, MTHFR C677T Polymorphism and Air Pollution (PM2.5) on Atherogenesis in Chinese Adults
ConclusionHC and PM2.5 pollution but not MTHFR genotype were both related to carotid IMT, independent of other traditional risk factors. This has potential implications in dietary and AP strategies for atherosclerosis prevention in China.
Source: The Journal of Nutrition, Health and Aging - February 3, 2023 Category: Nutrition Source Type: research

A Potential Strategy for Atherosclerosis Prevention in Modernizing China - Hyperhomocysteinemia, MTHFR C677T Polymorphism and Air Pollution (PM2.5) on Atherogenesis in Chinese Adults
CONCLUSION: HC and PM2.5 pollution but not MTHFR genotype were both related to carotid IMT, independent of other traditional risk factors. This has potential implications in dietary and AP strategies for atherosclerosis prevention in China.PMID:36806868 | DOI:10.1007/s12603-023-1889-x
Source: Atherosclerosis - February 22, 2023 Category: Cardiology Authors: C Y T Kwok Y K P Poon P Chook D S Guo C Q Lin Y H Yin D S Celermajer K S Woo Source Type: research