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Total 310 results found since Jan 2013.

Relationship Between Chinese Medicine Pattern Types, Clinical Severity, and Prognosis in Patients With Acute Cerebral Infarct
We investigated the relationship between Chinese medicine pattern (CMP) types, their severity, and prognosis in patients (n = 187) with acute cerebral infarct (ACI). Six CMPs (wind, phlegm, fire-heat, blood stasis, qi deficiency, and yin deficiency and yang hyperactivity) were evaluated according to inspection, listening and smelling, inquiry, and palpitation. The severity and prognosis of each pattern type was determined according to the Glasgow Coma Scale (GCS), Modified Rankin Scale (MRS), National Institutes of Health Stroke Scale (NIHSS), Barthel Index (BI), and Functional Independence Measure (FIM), recorded at strok...
Source: Explore - July 1, 2013 Category: Nursing Authors: Mao-chi Jhong, Nou-Ying Tang, Chung-Hsiang Liu, Wei-Hsih Huang, Yi-Ting Hsu, Yen-Liang Liu, Tsai-Chung Li, Ching-Liang Hsieh Tags: Original Research Source Type: research

Probable Nootropic-induced Psychiatric Adverse Effects: A Series of Four Cases
Conclusion Healthcare providers in general, and specifically those in the mental health and substance abuse fields, should keep in mind that nootropic use is an under recognized and evolving problem. Nootropic use should be considered in cases where there are sudden or unexplained exacerbations of psychiatric symptoms in patients who have been stable and medication adherent. It is also important to remember that most nootropics are not detected on standard drug toxicology screening tests. We have very little clinical information on how nootropics may interact with psychotropics (or other medications) and potentially cause ...
Source: Innovations in Clinical Neuroscience - December 1, 2015 Category: Neuroscience Authors: ICN Online Editor Tags: Case Series and Literature Review Current Issue Mental Disorders Psychiatry Psychopharmacology Substance Use Disorders Ampakines Armodafinil brain enhancer Cerebrolysin Citicoline cognitive enhancer homeopathic medicine natural r Source Type: research

Efficacy of trazodone for treating paroxysmal sympathetic hyperactivity presenting after thalamic hemorrhage: A case report.
Authors: Morinaga Y, Nii K, Sakamoto K, Inoue R, Mitsutake T, Hanada H Abstract Paroxysmal sympathetic hyperactivity (PSH) is a clinical condition characterized by abnormal paroxysmal surges in sympathetic nervous system activity. PSH is known to occur after severe head injury and hypoxic encephalopathy. Cases of PSH that develop after stroke have been reported worldwide; however, PSH is not commonly reported in the field of stroke research in Japan. Some studies have suggested that gabapentin may improve the symptoms of PSH. To our knowledge, this is the first case report demonstrating the efficacy of trazodone fo...
Source: Drug Discoveries and Therapeutics - July 23, 2019 Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research

Fasting Serum Glucose and Cholesterol as Predictors of Cardiovascular Reactivity to Acute Stress in a Sample of African American College Students.
CONCLUSIONS: FSG was a better predictor of cardiovascular reactivity to stress than serum cholesterol concentration, predicting mean arterial pressure and stroke volume. This finding may be due to the association of glucose with diabetes, which is more prevalent in African Americans. PMID: 26118145 [PubMed - in process]
Source: Ethnicity and Disease - June 30, 2015 Category: Global & Universal Tags: Ethn Dis Source Type: research

Imaging effects related to language improvements by rTMS.
Authors: Heiss WD Abstract The functional deficit after a focal brain lesion is determined by the localization and the extent of the tissue damage. Since destroyed tissue usually cannot be replaced in the adult human brain, improvement or recovery of neurological deficits can be achieved only by reactivation of functionally disturbed but morphologically preserved areas or by recruitment of alternative pathways within the functional network. The visualization of disturbed interaction in functional networks and of their reorganization in the recovery after focal brain damage is the domain of functional imaging modali...
Source: Restorative Neurology and Neuroscience - April 18, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Mania secondary to focal brain lesions: implications for understanding the functional neuroanatomy of bipolar disorder
ConclusionsSecondary mania should be suspected in patients with neurological deficits, histories atypical for classic bipolar disorder, and first manic episodes after the age of 40 years. Treatment with antimanic medications, along with specific treatment for the underlying neurologic condition, is typically required. Typical lesion locations fit with current models of bipolar disorder, which implicate hyperactivity of left‐hemisphere reward‐processing brain areas and hypoactivity of bilateral prefrontal emotion‐modulating regions. Lesion studies complement these models by suggesting that right‐hemisphere limbic‐...
Source: Bipolar Disorders - April 25, 2016 Category: Psychiatry Authors: David Satzer, David J Bond Tags: Review Article Source Type: research

Evaluations of Intravenous Administration of CD34 < sup > + < /sup > Human Umbilical Cord Blood Cells in a Mouse Model of Neonatal Hypoxic-Ischemic Encephalopathy
This study suggests that the treatment protocol needs to be optimized for each pathological condition.Dev Neurosci
Source: Developmental Neuroscience - January 19, 2017 Category: Neuroscience Source Type: research

Evaluations of Intravenous Administration of CD34+ Human Umbilical Cord Blood Cells in a Mouse Model of Neonatal Hypoxic-Ischemic Encephalopathy
This study suggests that the treatment protocol needs to be optimized for each pathological condition.Dev Neurosci
Source: Developmental Neuroscience - January 20, 2017 Category: Neuroscience Source Type: research

Development of Internet-Based Tasks for the Executive Function Performance Test.
CONCLUSION: The Internet-based tasks are comparable to the original EFPT tasks and can be used for assessment of EF deficits. PMID: 29426384 [PubMed - in process]
Source: The American Journal of Occupational Therapy - February 12, 2018 Category: Occupational Health Authors: Rand D, Lee Ben-Haim K, Malka R, Portnoy S Tags: Am J Occup Ther Source Type: research

The Applications of Pharmacogenomics to Neurological Disorders.
Abstract The most common neurological disorders, including neurodegenerative diseases and psychiatric disorders, have received recent attention with regards to pharmacogenomics and personalized medicine. Here, we will focus on a neglected neurodegenerative disorder, cerebral ischemic stroke (CIS), and highlight recent advances in two disorders, Parkinson's disease (PD) and Alzheimer's diseases (AD), that possess both similar and distinct mechanisms in regards to therapeutic targets. Current attempts to link symptoms from other disorders to candidate genes have been effective in identifying candidate genes for stro...
Source: Current Molecular Medicine - August 11, 2014 Category: Molecular Biology Authors: Gilman C, McSweeney C, Mao Y Tags: Curr Mol Med Source Type: research

Out of the Frying Pan, Into the Fire: A Case of Heat Shock and Its Fatal Complications
Abstract: Exertional heat stroke incidence is on the rise and has become the third leading cause of death in high school athletes. It is entirely preventable, yet this is a case of a 15-year-old, 97-kg male football player who presented unresponsive and hyperthermic after an August football practice. His blood pressure was 80/30, and his pulse was 180. He had a rectal temperature of 107.3°F, and upon entering the emergency department, he was rapidly cooled in 40 minutes. As he progressed, he developed metabolic acidosis, elevated liver enzymes, a prolapsed mitral valve with elevated troponin levels, and worsening hypotens...
Source: Pediatric Emergency Care - December 1, 2014 Category: Emergency Medicine Tags: Illustrative Cases Source Type: research

Paroxysmal sympathetic hyperactivity in neurological critical care
Conclusion: PSH is an unusual complication in neurocritical care. It prolonged the hospitalization and hampers recovery. The other life-threatening conditions that mimic PSH should be excluded. The association with JE and tuberculous meningitis was not previously described in literature.
Source: Indian Journal of Critical Care Medicine - January 6, 2015 Category: Intensive Care Authors: Rajesh VermaPrithvi GiriImran Rizvi Source Type: research

Autism in the Son of a Woman with Mitochondrial Myopathy and Dysautonomia: A Case Report
Conclusion Given emerging evidence that mitochondrial dysfunction, particularly in the electron transport chain needed for cellular energy production, is an underlying pathophysiological mechanism for some varieties of ASD, clinicians should have a high index of suspicion for mitochondrial disease, especially when they encounter a patient with unusual neurological or constitutional symptoms. The prevalence of mitochondrial disease in ASD patients may be as high as five percent, which means that it is not the “zebra”[27] diagnosis that it might be in a non-ASD patient, where prevalence is about 0.01 percent.10 Reference...
Source: Innovations in Clinical Neuroscience - October 9, 2015 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Asperger's syndrome Autism Behavioral and Cognitive Neurology Case Report Current Issue Intellectual Disability Neurologic Systems and Symptoms Pervasive Developmental Disorders ASD autism spectrum disorder dysauton Source Type: research

Environmental Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries
Conclusions Patterns of disease are changing rapidly in LMICs. Pollution-related chronic diseases are becoming more common. This shift presents a particular problem for children, who are proportionately more heavily exposed than are adults to environmental pollutants and for whom these exposures are especially dangerous. Better quantification of environmental exposures and stepped-up efforts to understand how to prevent exposures that cause disease are needed in LMICs and around the globe. To confront the global problem of disease caused by pollution, improved programs of public health monitoring and environmental protecti...
Source: EHP Research - March 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication March 2016 Source Type: research

Methylphenidate May Increase Risk for Arrhythmias, Myocardial Infarction In Some Youth
Findings from a study published in BMJ Open Access shows that some children and adolescents who are receiving methylphenidate for treatment of attention-deficit/hyperactivity disorder (ADHD) may be at increased risk for certain adverse cardiovascular events. "Drugs to treat ADHD have been shown to be efficacious in reducing symptoms of impulsivity and hyperactivity in children,” the study authors wrote, "but concerns have been expressed about possible adverse cardiovascular events with the first-line treatment, methylphenidate."To determine whether an association exists between methylphenidate and adverse cardiovascular ...
Source: Psychiatr News - June 3, 2016 Category: Psychiatry Tags: ADHD cardiovascular risk methylphenidate youth Source Type: research