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Condition: Heart Failure
Procedure: Perfusion
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Total 107 results found since Jan 2013.
Mechanisms of Stroke in Patients with Chronic Kidney Disease.
Abstract
BACKGROUND: Given the increasing worldwide prevalence of chronic kidney disease (CKD), it is critical to decrease the associated risk of debilitating vascular complications, including stroke, congestive heart failure, myocardial infarction, and peripheral vascular disease. Treatment options for reducing the risk of all subtypes of stroke in patients with CKD remain limited. For patients with end-stage kidney disease (ESKD), novel applications of noninvasive imaging may help personalize the type of dialysis and dialysis prescription for patients at high-risk.
SUMMARY: This manuscript reviews the heigh...
Source: American Journal of Nephrology - August 27, 2019 Category: Urology & Nephrology Authors: Ghoshal S, Freedman BI Tags: Am J Nephrol Source Type: research
Impact of MRI Selection on Triage of Endovascular Therapy in Acute Ischemic Stroke: The MRI in Acute Management of Ischemic Stroke (MIAMIS) Registry
Conclusions: Multimodality MRI screening for AIS symptoms for ET is feasible. Optimizing each center ’s protocol and the utilization of MRI with DWI only may be a time-saving alternative.Intervent Neurol 2019;8:135 –143
Source: Interventional Neurology - March 16, 2019 Category: Neurology Source Type: research
Updated Meta-analysis of Hemodilution in Acute Ischemic Stroke (P1.113)
CONCLUSION: Future work includes an additional reviewer to assess trial quality and CENTRAL search up to 2013. Overall, the results of this meta-analysis were comparable to the 2002 meta-analysis with a trend suggesting the possibility of harm with hemodilution therapy.Study Supported by:NIH NCATS UL1TR000427 and NHLBI Fellowship F30HL112491.Disclosure: Dr. Chang has nothing to disclose. Dr. Jensen has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chang, T., Jensen, M. Tags: Cerebrovascular Disease and Interventional Neurology: Antiplatelet Agents and Miscellaneous Source Type: research
Risk Factors for Blood-Brain Barrier Disruption in Patients with Chronic Cerebrovascular Disease Presenting with Acute Stroke (P2.245)
Conclusions: These findings suggest that cWMD caused by chronic hypertension may have a different underlying pathophysiology than cWMD that is associated with aging.Disclosure: Dr. Gupta has nothing to disclose. Dr. Luby has nothing to disclose. Dr. Nadareishvili has nothing to disclose. Dr. Benson has nothing to disclose. Dr. Hsia has nothing to disclose. Dr. Lynch has nothing to disclose. Dr. Leigh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gupta, N., Luby, M., Nadareishvili, Z., Benson, R., Hsia, A., Lynch, J., Leigh, R. Tags: Aging and Dementia: Other Source Type: research
Computed tomography perfusion in patients of stroke with left ventricular assist device
AbstractLeft ventricular assist devices (LVAD) are widely applied for patients with severe heart failure as a bridge to heart transplantation as well as destination therapy. Patients with implanted LVAD have an increased risk of cerebral thrombosis and computed tomographic perfusion (CTP) has the potential to be performed for early diagnosis and treatment of acute ischemic stroke (AIS), including interventional thrombectomy. Here, we report our series of CTP examination in patients having suspected AIS after LVAD implantation. We retrospectively investigated 33 contrast-enhanced CTPs from January 2017 to December 2018 whic...
Source: Heart and Vessels - August 9, 2020 Category: Cardiology Source Type: research
Potential Applications of Remote Limb Ischemic Conditioning for Chronic Cerebral Circulation Insufficiency
Conclusion
Due to its long-term and often invisible course, CCCI has received less attention than acute cerebral ischemic stroke. However, without appropriate intervention, CCCI may lead to a variety of adverse events. Because the pathophysiological changes associated with CCCI are complex, pharmacological research in this area has been disappointing. Recent research suggests that RLIC, which is less invasive and more well-tolerated than drug treatment, can activate endogenous protective mechanisms during CCCI. In the present report, we reviewed studies related to CCCI (Table 1), as well as those related to stroke and sta...
Source: Frontiers in Neurology - May 2, 2019 Category: Neurology Source Type: research
A Serious Diagnosis Lacking Common Symptoms
BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; & AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regi...
Source: The Case Files - May 28, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: research
Combined brain/heart magnetic resonance imaging in antiphospholipid syndrome-two sides of the same coin
AbstractAntiphospholipid syndrome (APS) is an autoimmune disorder characterized by arterial, venous, and/or small vessel thrombosis, pregnancy morbidity, and persistently elevated levels of antiphospholipid antibodies (aPL). Cardiovascular disease (CVD) in APS can present as heart valvular disease (HVD), macro-micro-coronary artery disease (CAD), myocardial dysfunction, cardiac thrombi, or pulmonary hypertension. Brain disease presents as stroke or transient ischemic attack (TIA) and less frequently as cerebral venous thrombosis, seizures, cognitive dysfunction, multiple sclerosis (MS) −like syndrome, or chorea. Infarcts...
Source: Clinical Rheumatology - June 10, 2021 Category: Rheumatology Source Type: research
Left ventricular assist device implantation combined with hemiarch replacement for severe aortic atherosclerosis
J Thorac Dis. 2023 Jul 31;15(7):3979-3983. doi: 10.21037/jtd-23-255. Epub 2023 Jul 6.ABSTRACTImplantation of the left ventricular assist device (LVAD) has emerged as a widely employed therapeutic approach for specifically chosen individuals suffering from severe heart failure. Stroke is a well-known complication of LVAD implantation. Concomitant aortic surgeries in patients requiring LVAD implantation to avoid outflow graft anastomosis to a severe atherosclerotic aorta are unknown. We illustrate a successful LVAD implantation with hemiarch replacement for severe aortic atherosclerosis to decrease the risk of postoperative ...
Source: Atherosclerosis - August 10, 2023 Category: Cardiology Authors: June Lee Seok Beom Hong Yong Han Kim Hwan Wook Kim Do Yeon Kim Source Type: research
Incidence and Predictors of Cognitive Decline in Patients with Left Ventricular Assist Devices Original Articles
Conclusions—
Cognitive decline occurs commonly in patients in the year after LVAD and is associated with older age and destination therapy. These results could have important implications for patient selection and improved communication of risks before LVAD implantation. Additional studies are needed to explore the association between cognitive decline and subsequent stroke, health status, and mortality in patients after LVAD.
Source: Circulation: Cardiovascular Quality and Outcomes - May 19, 2015 Category: Cardiology Authors: Fendler, T. J., Spertus, J. A., Gosch, K. L., Jones, P. G., Bruce, J. M., Nassif, M. E., Flint, K. M., Dunlay, S. M., Allen, L. A., Arnold, S. V. Tags: Other heart failure Original Articles Source Type: research
Abstract 1: Incidence and Predictors of Cognitive Decline in Patients with Left Ventricular Assist Devices Session Title: Concurrent Session IB: Oral Abstracts - QCOR Young Investigator Awards
Conclusion: In a large LVAD registry, cognitive decline occurred in over a quarter of patients in the year after LVAD and was associated with older age, renal disease, higher baseline cognitive function, and more stable heart failure at implant. These results define the frequency of an important adverse event and provide new insights regarding outcomes after LVAD. Future studies are needed to explore the association of transient and permanent cognitive decline with subsequent stroke, health status, and mortality in patients after LVAD placement.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Fendler, T. J., Spertus, J. A., Gosch, K., Jones, P. G., Bruce, J. M., Nassif, M. E., Flint, K. M., Dunlay, S. M., Allen, L. A., Arnold, S. V. Tags: Session Title: Concurrent Session IB: Oral Abstracts - QCOR Young Investigator Awards Source Type: research
Age-Dependence of Flow Homeostasis in the Left Ventricle
Conclusions: In average, blood spends 1 to 3 beats inside the LV with very low shear stress rates. The apical region is the most prone to blood stasis, particularly in mid-aged adults. The washout of blood in the normal LV is age-dependent due to physiological changes in the degree of apical penetration of the filling waves.
Introduction
Cardioembolic stroke is a major source of mortality and disability worldwide and blood stasis one of its major determinants (Adams et al., 1986). Left ventricular (LV) function has evolved to maximize mechanical efficiency and ensure organ perfusion at a low cost of energy and fill...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research
089 * innominate artery cannulation for proximal aortic surgery: outcomes and neurologic events in 263 patients
Conclusion: Innominate artery cannulation can be performed safely and poses a low risk of neurologic events in procedures requiring hypothermic circulatory arrest. This artery may be considered the optimal perfusion site for delivering ACP.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Preventza, O., Garcia, A., Tuluca, A., Henry, M., Bakaeen, F., Omer, S., Cornwell, L., Coselli, J. S. Tags: Part II: Cannulation issues in aortic surgery: Doing things right or doing the right things Source Type: research
The Mechanoreflex and Hemodynamic Response to Passive Leg Movement in Heart Failure
Background: Sensitization of mechanosensitive afferents, which contribute to the exercise pressor reflex, has been recognized as a characteristic of patients with heart failure (HF); however, the hemodynamic implications of this hypersensitivity are unclear.
Objectives: The present study used passive leg movement (PLM) and intrathecal injection of fentanyl to blunt the afferent portion of this reflex arc to better understand the role of the mechanoreflex on central and peripheral hemodynamics in HF.
Methods: Femoral blood flow (FBF), mean arterial pressure, femoral vascular conductance, HR, stroke volume, cardiac output,...
Source: Medicine and Science in Sports and Exercise - February 19, 2016 Category: Sports Medicine Tags: Basic Sciences Source Type: research
The emerging role of galectins in cardiovascular disease.
Abstract
Galectins are an ancient family of β-galactoside-specific lectins and consist of 15 different types, each with a specific function. They play a role in the immune system, inflammation, wound healing and carcinogenesis. In particular the role of galectin in cancer is widely studied. Lately, the role of galectins in the development of cardiovascular disease has gained attention. Worldwide cardiovascular disease is still the leading cause of death. In ischemic heart disease, atherosclerosis limits adequate blood flow. Angiogenesis and arteriogenesis are highly important mechanisms relieving ischemia by rest...
Source: Vascular Pharmacology - March 2, 2016 Category: Drugs & Pharmacology Authors: van der Hoeven NW, Hollander MR, Yıldırım C, Jansen MF, Teunissen PF, Horrevoets AJ, van der Pouw Kraan TC, van Royen N Tags: Vascul Pharmacol Source Type: research
