The Mechanoreflex and Hemodynamic Response to Passive Leg Movement in Heart Failure

Conclusions: Although movement-induced central hemodynamics were unchanged by afferent blockade, peripheral hemodynamic responses were significantly enhanced. Thus, in patients with HF, a heightened mechanoreflex seems to augment peripheral sympathetic vasoconstriction in response to movement, a phenomenon that may contribute to exercise intolerance in this population.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: Basic Sciences Source Type: research