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Condition: Autoimmune Disease
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Total 584 results found since Jan 2013.
Salt and miscarriage: is there a link?
Salt is a major mineral element that plays fundamental roles in health and disease. Excessive salt intake is a major cause of hypertension, cardiovascular disease and stroke. Miscarriage and preeclampsia are the most common pregnancy complications with multiple etiological factors, including inflammatory and autoimmune conditions. More recently, different studies indicated that excessive salt intake is involved in the development of inflammatory processes through induction of T helper-17 pathway and their inflammatory cytokines.
Source: Medical Hypotheses - February 9, 2016 Category: Biomedical Science Authors: Amir Abdoli Source Type: research
Clopidogrel-induced refractory thrombotic thrombocytopenic purpura successfully treated with rituximab
Publication date: Available online 2 December 2015 Source:Hematology/Oncology and Stem Cell Therapy Author(s): Sara Khodor, Miguel Castro, Colin McNamara, Chakra P. Chaulagain Thrombotic thrombocytopenic purpura (TTP) is a multisystem disorder characterized by microvascular aggregation of platelets and fibrin strands causing thrombocytopenia, microangiopathic hemolytic anemia, and organ dysfunction. TTP can develop as a result of a deficiency in ADAMTS13 enzyme activity due to either a genetic defect or, more commonly, the development of anti-ADAMTS13 autoantibodies. TTP can also be associated with pregnancy, organ t...
Source: Hematology Oncology and Stem Cell Therapy - March 7, 2016 Category: Cancer & Oncology Source Type: research
Parkinson's disease and multiple sclerosis are not associated with autoantibodies against structural proteins of the dermal‐epidermal junction
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - March 12, 2016 Category: Dermatology Authors: A. Recke, A. Oei, F. Hübner, K. Fechner, J. Graf, J. Hagenah, C. May, D. Woitalla, A. Salmen, D. Zillikens, R. Gold, W. Schlumberger, E. Schmidt Tags: Research Letter Source Type: research
Parkinson's disease and multiple sclerosis are not associated with autoantibodies against structural proteins of the dermal-epidermal junction.
This article is protected by copyright. All rights reserved.
PMID: 26972435 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - March 12, 2016 Category: Dermatology Authors: Recke A, Oei A, Hübner F, Fechner K, Graf J, Hagenah J, May C, Woitalla D, Salmen A, Zillikens D, Gold R, Schlumberger W, Schmidt E Tags: Br J Dermatol Source Type: research
Obstructive Sleep Apnea in Patients with Branch Retinal Vein Occlusion: A Preliminary Study.
CONCLUSIONS: We found a higher than expected rate of OSA in BRVO patients lacking concomitant diseases typically associated with OSA. Our findings suggest that OSA could be an additional risk factor in the pathogenesis of BRVO or at least a frequently associated condition that could function as a triggering factor.
PMID: 27051260 [PubMed - as supplied by publisher]
Source: Korean Journal of Ophthalmology : KJO - April 7, 2016 Category: Opthalmology Tags: Korean J Ophthalmol Source Type: research
Is it ever lupus? A single centre retrospective review of the rheumatologic work-up in patients with clinically isolated syndrome (P6.113)
Conclusions: In our single centre review of patients with CIS who underwent rheumatologic testing, ANA was weakly/moderately positive in 64[percnt] and did not aid in predicting diagnosis of MS versus an autoimmune rheumatologic disease. More specific rheumatologic markers, including ds-DNA, ENA, low C3/C4 and antiphospholipid antibodies were rarely positive, and no CIS was attributed to a newly diagnosed rheumatologic disease.Disclosure: Dr. Budhram has nothing to disclose. Dr. Yuen has nothing to disclose. Dr. Yan has nothing to disclose. Dr. Kremenchutzky has received research support from Bayer, Biogen Idec, Genzyme, N...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Budhram, A., Yuen, J., Yan, H., Kremenchutzky, M. Tags: MS and CNS Inflammatory Disease: CNS Inflammatory Diseases and Differential Diagnosis Source Type: research
Primary Sjögren's syndrome presenting with multiple aneurysmal dilatation of cerebral arteries and causing repetitive intracranial hemorrhage
Sjögren's syndrome (SS) is characterized by mononuclear infiltration and destruction of salivary and lachrymal glands leading to xerostomia and xerophthalmia [1]. This syndrome is classified as primary SS in the absence of other autoimmune diseases, and as secondary SS when it is associated with other autoimmune diseases such as rheumatoid arthritis, scleroderma, and systemic lupus erythematosus. The incidence of stroke among patients with SS is 2% and SS is even more rarely complicated with cerebral artery lesions [2].
Source: Journal of the Neurological Sciences - April 18, 2016 Category: Neurology Authors: Teppei Komatsu, Hidetaka Mitsumura, Ichiro Yuki, Yasuyuki Iguchi Tags: Letter to the Editor Source Type: research
Don't Simply Turn Away
Did you know that there are 35 national health observances that take place during the month of May?
To name a few: Hepatitis and Stroke Awareness Month, Mental Health Month, Teen Pregnancy Prevention, National Physical Education and Sport Week, National Bike to School Day and World Autoimmune Awareness Day. There are a total of 213 national health observances throughout the year.
Some might ask:
"Is of all this necessary?"
"Aren't 213 observances a bit of an overkill?"
"Why so many?"
We often hear these questions because the majority of people don't really understand the hardships, difficulties, and struggles of ot...
Source: Healthy Living - The Huffington Post - May 3, 2016 Category: Consumer Health News Source Type: news
Hepatitis C virus and neurological damage.
Authors: Mathew S, Faheem M, Ibrahim SM, Iqbal W, Rauff B, Fatima K, Qadri I
Abstract
Chronic hepatitis C virus (HCV) infection exhibits a wide range of extrahepatic complications, affecting various organs in the human body. Numerous HCV patients suffer neurological manifestations, ranging from cognitive impairment to peripheral neuropathy. Overexpression of the host immune response leads to the production of immune complexes, cryoglobulins, as well as autoantibodies, which is a major pathogenic mechanism responsible for nervous system dysfunction. Alternatively circulating inflammatory cytokines and chemokines and...
Source: World Journal of Hepatology - May 4, 2016 Category: Gastroenterology Tags: World J Hepatol Source Type: research
Complications of Cushing's syndrome: state of the art
Publication date: Available online 10 May 2016 Source:The Lancet Diabetes & Endocrinology Author(s): Rosario Pivonello, Andrea M Isidori, Maria Cristina De Martino, John Newell-Price, Beverly M K Biller, Annamaria Colao Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive secretion of cortisol. The syndrome is associated with increased mortality and impaired quality of life because of the occurrence of comorbidities. These clinical complications include metabolic syndrome, consisting of systemic arterial hypertension, visceral obesity, impairment of glucose metaboli...
Source: The Lancet Diabetes and Endocrinology - May 11, 2016 Category: Endocrinology Source Type: research
Neurological complications of acute multifocal placoid pigment epitheliopathy
The objective of this patient series is to describe the neurological complications of AMPPE. We retrospectively identified patients with neurological complications of AMPPE seen at Auckland Hospital between 2008 and 2013 and summarised cases in the literature between 1976 and 2013. We identified five patients with neurological complications of AMPPE at Auckland Hospital and 47 reported patients. These patients demonstrated a spectrum of neurological involvement including isolated headache, stroke or transient ischaemic attack, seizures, venous sinus thrombosis, optic neuritis, sensorineural hearing loss and peripheral vest...
Source: Journal of Clinical Neuroscience - May 11, 2016 Category: Neuroscience Source Type: research
Phytocannabinoids and cannabimimetic drugs: recent patents in central nervous system disorders.
CONCLUSIONS: Finally, although the study of the mechanisms of action of these compounds is still unsolved, many reports and patents strongly suggest therapeutic potential of these compounds in neurological diseases.
PMID: 27184693 [PubMed - as supplied by publisher]
Source: Recent Patents on CNS Drug Discovery - May 18, 2016 Category: Drugs & Pharmacology Tags: Recent Pat CNS Drug Discov Source Type: research
Vitamin D Deficiency Is As Dangerous As Smoking
The advice you’re getting from your doctor, the TV and even the Surgeon General is so wrong, it’s scary.
They’re all busy telling you to stay out of the sun.
But Swedish researchers recently discovered that nonsmokers who avoid the sun have a life expectancy similar to smokers who spend a lot of time in the sun.
Staying out of the sun is as dangerous as smoking.1
It doesn’t surprise me. I tell all my patients sunlight exposure is essential to our health because it is the best source of vitamin D… possibly the most important nutrient we know of.
Mainstream medicine still doesn’t recognize th...
Source: Al Sears, MD Natural Remedies - May 19, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news
TRAF3IP2 mediates atherosclerotic plaque development and vulnerability in ApoE−/− mice
Atherosclerosis is a major cause of heart attack and stroke. Inflammation plays a critical role in the development of atherosclerosis. Since the cytoplasmic adaptor molecule TRAF3IP2 (TRAF3-Interacting Protein 2) plays a causal role in various autoimmune and inflammatory diseases, we hypothesized that TRAF3IP2 mediates atherosclerotic plaque development.
Source: Atherosclerosis - May 18, 2016 Category: Cardiology Authors: Siva Sankara Vara Prasad Sakamuri, Yusuke Higashi, Sergiy Sukhanov, Jalahalli M. Siddesha, Patrice Delafontaine, Ulrich Siebenlist, Bysani Chandrasekar Source Type: research
Turmeric: Bali’s Anti-Cancer Tonic
I’m always happy to find things in my travels to bring back to you. Today I want to tell you about a miracle of nature called turmeric.
Turmeric has been used to treat a wide variety of conditions.
You can read about it in-depth in my latest book, Healing Herbs of Paradise.
The roots of this exotic leafy plant contain curcumin, a very powerful antioxidant that also has remarkable anti-inflammatory properties.1,2,3
What Does Curcumin Do?
Curcumin neutralizes free radicals… those nasty little chemicals that travel through your body and cause damage to healthy cells and cell membranes.
Which means curcumin effectivel...
Source: Al Sears, MD Natural Remedies - May 25, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Cancer Source Type: news
