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Total 234 results found since Jan 2013.

Novel Derivatives of Docosahexaenoylethanolamide as Therapeutics for Neuronal Disorders
This technology provides derivatives of Docosahexaenoylethanolamide (synaptamide or DEA) which have increased potency and hydrolysis resistance as compared to DEA (structures of these derivatives are available upon request), as well as methods of using these derivatives to promote neurogenesis, neurite growth, and/or synaptogenesis. Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid that accumulates in the brain during development, has been shown to play a key role in learning and memory development. Studies have also shown that DEA, a metabolite derived from DHA is very potent in accelerating neuronal growth an...
Source: NIH OTT Licensing Opportunities - January 24, 2013 Category: Research Authors: admin Source Type: research

Environmental Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries
Conclusions Patterns of disease are changing rapidly in LMICs. Pollution-related chronic diseases are becoming more common. This shift presents a particular problem for children, who are proportionately more heavily exposed than are adults to environmental pollutants and for whom these exposures are especially dangerous. Better quantification of environmental exposures and stepped-up efforts to understand how to prevent exposures that cause disease are needed in LMICs and around the globe. To confront the global problem of disease caused by pollution, improved programs of public health monitoring and environmental protecti...
Source: EHP Research - March 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication March 2016 Source Type: research

Heart attacks linked to media statin reports ... reports media
Conclusion This study aimed to estimate the effect on the use of statins in the UK after a six-month period of intense media coverage about the risks and benefits of the drugs. It found that patients were more likely to stop taking statins after exposure to the high media coverage compared with before the six-month period. However, there was no effect for people who had been newly prescribed statins. As the researchers acknowledge, interrupted time series studies like this one cannot confirm a causal link between the media coverage and the observed likelihood of stopping statin treatment. We cannot know the exact reasons...
Source: NHS News Feed - June 29, 2016 Category: Consumer Health News Tags: Heart/lungs Medication Medical practice Source Type: news

Derivatives of Docosahexaenoylethanolamide (DEA) for Neurogenesis
The invention pertains to derivatives of docosahexaenoylethanolamide (synaptamide or DEA) and their use in inducing neurogenesis, neurite growth, and/or synaptogenesis. As such, these DEA derivatives can be used as therapeutics for neurodegenerative diseases such as traumatic brain injury, spinal cord injury, peripheral nerve injury, stroke, multiple sclerosis, autism, Alzheimer ' s disease, Huntington ' s disease, Parkinson ' s disease, amyotrophic lateral sclerosis. The DEA derivatives of the invention have increased potency and hydrolysis resistance as compared to native DEA. Docosahexaenoic acid (DHA), an n-3 polyunsat...
Source: NIH OTT Licensing Opportunities - January 24, 2013 Category: Research Authors: ajoyprabhu3 Source Type: research

AI Solution Detects Autism in Toddlers
A digital healthcare startup is using an artificial intelligence (AI) platform to help aid in the detection of autism. Palo Alto, CA -based Cognoa said FDA has classified the algorithm-powered solution as a Class II diagnostic medical device. The FDA designation gives the company a path to get full clearance as a medical diagnostic for autism. “The goal actually is this summer to submit to the FDA to get full clearance under a de novo as a medical diagnostic,” Sharief Taraman, vice president of medical at Cognoa, told MD+DI. “I think we should be able to get that at the end of the year or by 2019.” Network with y...
Source: MDDI - February 22, 2018 Category: Medical Devices Authors: Omar Ford Tags: Medical Device Business Digital Health Source Type: news

Transcriptomic Analysis of Mecp2 Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain
This study was carried out in accordance with the recommendations of National Animal Welfare Authority, Ireland. The protocol was approved by the Animal Ethical Committee Trinity College Dublin and HPRA.Author ContributionsAS performed the experiments and wrote the paper; KH provided assistance in the design and analysis of the RNAseq experiment; DT contributed to sample extraction and establishment of the colony; and DT and MG designed and supervised all the parts of the research and the writing of the manuscript.FundingThe study was funded by the Wellcome Trust Grant WT079408/C/06/Z issued to MG, and by an SFI FN Funded ...
Source: Frontiers in Psychiatry - April 29, 2019 Category: Psychiatry Source Type: research

NHS funds headache relieving device
The handheld device delivers low-level electric currents to disrupt cluster headaches Related items fromOnMedica NICE calls for consistent clinical and social care in cerebral palsy Stroke survivors need more help taking medicine Ending the postcode lottery of stroke care BMA calls for ‘national standard for autism care’ Clinicians need better options if we are to stop over-medication
Source: OnMedica Latest News - May 6, 2019 Category: UK Health Source Type: news

The future of transcranial magnetic stimulation in neuroscience and neurology in the Middle East.
CONCLUSIONS: By paying special consideration to a Middle Eastern context, we aimed at illustrating the possibilities that TMS could bring for clinicians and patients in this nationally prioritized research field. PMID: 31173309 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - June 9, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Prevalence and Diagnosis of Neurological Disorders Using Different Deep Learning Techniques: A  Meta-Analysis
This study confers the discipline, frameworks, and methodologies used by different deep learning techniques to diagnose different human neurological disorders. Here, one hundred and thirty-six different articles related to neurological and neuropsychiatric disorders diagnosed using different deep learning techniques are studied. The morbidity and mortality rate of major neuropsychiatric and neurological disorders has also bee n delineated. The performance and publication trend of different deep learning techniques employed in the investigation of these diseases has been examined and analyzed. Different performance metrics ...
Source: Journal of Medical Systems - January 3, 2020 Category: Information Technology Source Type: research

Why is Music Therapeutic for Neurological Disorders? The Therapeutic Music Capacities Model
Publication date: Available online 9 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Olivia Brancatisano, Amee Baird, William Forde ThompsonAbstractMusic has cognitive, psychosocial, behavioral and motor benefits for people with neurological disorders such as dementia, stroke, Parkinson’s disease and Autism Spectrum Disorder. Here we discuss seven properties or ‘capacities’ of music that interact with brain function and contribute to its therapeutic value. Specifically, in its various forms, music can be engaging, emotional, physical, personal, social and persuasive, and it promotes synchronizatio...
Source: Neuroscience and Biobehavioral Reviews - February 10, 2020 Category: Neuroscience Source Type: research

Fecal Microbiota Transplantation in Neurological Disorders
Conclusions: Preliminary literature suggests that FMT may be a promising treatment option for several neurological disorders. However, available evidence is still scanty and some contrasting results were observed. A limited number of studies in humans have been performed or are ongoing, while for some disorders only animal experiments have been conducted. Large double-blinded randomized controlled trials are needed to further elucidate the effect of FMT in neurological disorders.
Source: Frontiers in cellular and infection microbiology - March 23, 2020 Category: Microbiology Source Type: research

Single mutation leads to big effects in autism-related gene
(NIH/National Institute of Neurological Disorders and Stroke) A new study in Neuron offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases. The study was conducted at NIH's National Institute of Neurological Disorders and Stroke (NINDS).
Source: EurekAlert! - Medicine and Health - April 2, 2020 Category: International Medicine & Public Health Source Type: news

TV highlights 08/01/2013
Stargazing Live | Death In Paradise | The Undateables | Primeval: New World | Taboo | PramfaceStargazing Live8pm, BBC2In what looks like it will be an annual fixture, Professor Brian Cox scans the night skies with that infectiously awestruck, half-moon smile of his. He's accompanied once more by comedian Dara Ó Briain, who makes for an effective sidekick with his comic rather than cosmic background and demeanour. He is shown how to spot and take pictures of celestial marvels, followed by half an hour of discussion with an invited audience over what hidden glories the telescope has revealed. David StubbsDeath In Paradise9p...
Source: Guardian Unlimited Science - January 7, 2013 Category: Science Authors: David Stubbs, Martin Skegg, Hannah Verdier, Ali Catterall, Ben Arnold Tags: The Guardian Astronomy Culture Television & radio Brian Cox Editorial Science amp; radio Source Type: news

Lord Kelvin Adam Smith Fellowship: University of Glasgow, UK
Added via www.academicpositions.co.uk. The University of Glasgow is offering Lord Kelvin Adam Smith fellowship appointments in the College of Medical, Veterinary & Life Sciences as part of a major programme of investment in the University’s future research portfolio. Our fellowship packages are aimed at attracting outstanding researchers and providing them with support and mentoring to develop their own careers within our world-leasing research environment. At Glasgow, fellowship holders will benefit from a proven peer group mentoring programme and have the opportunity to be transferred to an open ended lecturin...
Source: Society for Endocrinology - January 10, 2013 Category: Endocrinology Source Type: news

New Project Would Map The Human Brain
Melissa Block speaks with Dr. Story Landis, director of the National Institute of Neurological Disorders and Stroke, about the Brain Activity Map project written about in today's New York Times. If it goes forward, the project would seek to find treatments for Alzheimer's, Parkinson's, autism, psychiatric disorders and more.» E-Mail This     » Add to Del.icio.us
Source: NPR Health and Science - February 18, 2013 Category: Consumer Health News Source Type: news