Integrating faces and bodies: Psychological and neural perspectives on whole person perception
Publication date: Available online 20 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Ying Hu, Asal Baragchizadeh, Alice J. O’TooleAbstractThe human “person” is a common percept we encounter. Research on person perception has been focused either on face or body perception—with less attention paid to whole person perception. We review psychological and neuroscience studies aimed at understanding how face and body processing operate in concert to support intact person perception. We address this question considering: a.) the task to be accomplished (identification, emotion proc...
Source: Neuroscience and Biobehavioral Reviews - February 21, 2020 Category: Neuroscience Source Type: research

Neural circuits of idiopathic Normal Pressure Hydrocephalus: A perspective review of brain connectivity and symptoms meta-analysis
Publication date: Available online 20 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Alessandra Griffa, Dimitri Van De Ville, François R. Herrmann, Gilles AllaliAbstractIdiopathic normal pressure hydrocephalus (iNPH) is a prevalent reversible neurological disorder characterized by impaired locomotion, cognition and urinary control with ventriculomegaly. Symptoms can be relieved with cerebrospinal fluid drainage, which makes iNPH the leading cause of reversible dementia. Because of a limited understanding of pathophysiological mechanisms, unspecific symptoms and the high prevalence of comorbi...
Source: Neuroscience and Biobehavioral Reviews - February 21, 2020 Category: Neuroscience Source Type: research

Examination of peripheral basal and reactive cortisol levels in major depressive disorder and the burnout syndrome: A systematic review
Publication date: Available online 20 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): N. Rothe, J. Steffen, M. Penz, C. Kirschbaum, A. WaltherAbstractIt is debated as to whether major depressive disorder (MDD) and the burnout syndrome represent different aspects of the same syndrome or whether they reflect separate entities. A dysregulation of the hypothalamus-pituitary-adrenal-axis has been related to both conditions separately. Dissecting the pathophysiology of the conditions and describing differences and similarities with regard to stress physiological systems might further clarify whether under...
Source: Neuroscience and Biobehavioral Reviews - February 21, 2020 Category: Neuroscience Source Type: research

The Twin Representativeness Assumption
Publication date: Available online 20 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Kaare Christensen, Matt McGue (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - February 21, 2020 Category: Neuroscience Source Type: research

Parsing the components of forgiveness: Psychological and neural mechanisms
Publication date: Available online 20 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Melike M. Fourie, Ruud Hortensius, Jean DecetyAbstractForgiveness―a shift in motivation away from retaliation and avoidance towards increased goodwill for the perceived wrongdoer―is vital for restoring social relationships and positively impacts personal wellbeing and society at large. Parsing the psychological and neurobiological mechanisms of forgiveness remains an outstanding challenge (not least because of conceptual and methodological difficulties in the field), but contributes theoretical clarity. Here, w...
Source: Neuroscience and Biobehavioral Reviews - February 20, 2020 Category: Neuroscience Source Type: research

Childhood maltreatment and DNA methylation: A systematic review
Publication date: Available online 17 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Charlotte A.M. Cecil, Yuning Zhang, Tobias NolteAbstractDNA methylation (DNAm) – an epigenetic process that regulates gene expression – may represent a mechanism for the biological embedding of early traumatic experiences, including childhood maltreatment. Here, we conducted the first systematic review of human studies linking childhood maltreatment to DNAm. In total, 72 studies were included in the review (2008-2018). The majority of extant studies (i) were based on retrospective data in adults, (ii) e...
Source: Neuroscience and Biobehavioral Reviews - February 18, 2020 Category: Neuroscience Source Type: research

Fibrinogen and risk of dementia: A systematic review and meta-analysis
Publication date: Available online 17 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Zhike Zhou, Yifan Liang, Xiaoqian Zhang, Junjie Xu, Jueying Lin, Rongwei Zhang, Kexin Kang, Huiling Qu, Chuansheng Zhao, Mei ZhaoAbstractBackgroundThe aim of this meta-analysis is to evaluate the association of fibrinogen with risk of dementia and its subtypes.MethodsEmbase, Pubmed and Web of Science were retrieved systematically up to February 2019. Standard mean difference (SMD) with 95% confidence intervals was estimated using random-effects models.ResultsSixteen studies involving 3,649 participants were summari...
Source: Neuroscience and Biobehavioral Reviews - February 18, 2020 Category: Neuroscience Source Type: research

Retinoic Acid and Depressive Disorders: Evidence and Possible Neurobiological Mechanisms
Publication date: Available online 15 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Pu Hu, Anne-Marie van Dam, Yu Wang, Paul J. Lucassen, Jiang-Ning ZhouAbstractThe retinoid family members, including vitamin A and derivatives like 13-cis-retinoic acid (ITT) and all-trans retinoic acid (ATRA), are essential for normal functioning of the developing and adult brain. When vitamin A intake is excessive, however, or after ITT treatment, increased risks have been reported for depression and suicidal ideation.Here, we review pre-clinical and clinical evidence supporting association between retinoids and d...
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

A sensorimotor control framework for understanding emotional communication and regulation
Publication date: Available online 15 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Justin Williams, Charlotte Huggins, Barbra Zupan, Megan Willis, Tamsyn Van Rheenen, Wataru Sato, Romina Palermo, Catherine Ortner, Martin Krippl, Mariska Kret, Joanne Dickson, Chiang-shan Li, Leroy LoweAbstractOur research team was asked to consider the relationship of the neuroscience of sensorimotor control to the language of emotions and feelings. Actions are the principal means for the communication of emotions and feelings in both humans and other animals, and the allostatic mechanisms controlling action also ...
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

Omega-3 and its domain-specific effects on cognitive test performance in youths: a meta-analysis
Publication date: Available online 15 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Sophie Emery, Isabelle Häberling, Gregor Berger, Susanne Walitza, Klaus Schmeck, Therese Albert, Noemi Baumgartner, Michael Strumberger, Mona Albermann, Renate DrechslerAbstractOmega-3 fatty acids are vital for brain development. The aim of this meta-analysis was to broaden current knowledge of the effects of omega-3 supplementation on cognitive test performance in youths. Randomized controlled trials (RCTs) meeting selection criteria were identified through two independent literature searches on PubMed, Cochr...
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

Twin study designs as a tool to identify new candidate genes for depression: A systematic review of DNA methylation studies
Publication date: Available online 14 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Helena Palma-Gudiel, Aldo Córdova-Palomera, Víctor Navarro, Lourdes FañanásAbstractMonozygotic (MZ) twin studies constitute a key resource for the dissection of environmental and biological risk factors for human complex disorders. Given that epigenetic differences accumulate throughout the lifespan, the assessment of MZ twin pairs discordant for depression offers a genetically informative design to explore DNA methylation while accounting for the typical confounders of the field, shared...
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

Heart rate variability in patients with somatic symptom disorders and functional somatic syndromes: a systematic review and meta-analysis
Publication date: Available online 14 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Cheng Ying-Chih, Huang Yu-Chen, Huang Wei-LiehAbstractThis research is aimed to systematically review heart rate variability (HRV) findings of functional somatic syndrome (FSSs) and somatic symptom disorders (SSDs), and to compare the HRV values between FSSs/SSDs patients and healthy individuals. We included clinical studies assessing HRV (including baseline HRV and HRV reactivity) in FSSs/SSDs and healthy participants. We searched PubMed, Embase, PsycINFO, MEDLINE, and Web of Science databases from the earliest av...
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

The twin model: A silent success story in brain, cognition and behaviour research
Publication date: Available online 14 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Corrado Fagnani, Maria Antonietta Stazi (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

Behavioural and psychological symptoms of dementia in mouse models of Alzheimer’s disease-related pathology: Running title: BPSD in Alzheimer’s disease models
Publication date: Available online 15 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Filip Kosel, Jessica M.S. Pelley, Tamara B. FranklinAbstractTransgenic mouse models have been used extensively to model the cognitive impairments arising from Alzheimer’s disease (AD)-related pathology. However, less is known about the relationship between AD-related pathology and the behavioural and psychological symptoms of dementia (BPSD) commonly presented by patients. This review discusses the BPSD-like behaviours recapitulated by several mouse models of AD-related pathology, including the APP/PS1, Tg257...
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

Editorial Board
Publication date: April 2020Source: Neuroscience & Biobehavioral Reviews, Volume 111Author(s): (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - February 16, 2020 Category: Neuroscience Source Type: research

Anticipatory feelings: neural correlates and linguistic markers
Publication date: Available online 13 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Elka Stefanova, Olga Dubljević, Cornelia Herbert, Beth Fairfield, Matthias L. Schroeter, Emily R. Stern, Sébastien Urben, Birgit Derntl, Christine Wiebking, Carina Brown, Anat Drach -Zahavy, Leonie Ann Kathrin Loeffler, Franziska Albrecht, Rocco Palumbo, Sydney Weber Boutros, Jacob Raber, Leroy LoweAbstractThis review introduces anticipatory feelings (AF) as a new construct related to the process of anticipation and prediction of future events. AF, defined as the state of awareness of physiological and neur...
Source: Neuroscience and Biobehavioral Reviews - February 15, 2020 Category: Neuroscience Source Type: research

Anatomical And Clinical Implications Of Vagal Modulation Of The Spleen
Publication date: Available online 12 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Gabriel S. Bassi, Alexandre Kanashiro, Norberto C. Coimbra, Niccolò Terrando, William Maixner, Luis UlloaAbstractThe vagus nerve coordinates most physiologic functions including the cardiovascular and immune systems. This mechanism has significant clinical implications because electrical stimulation of the vagus nerve can control inflammation and organ injury in infectious and inflammatory disorders. The complex mechanisms that mediate vagal modulation of systemic inflammation are mainly regulated via the sp...
Source: Neuroscience and Biobehavioral Reviews - February 13, 2020 Category: Neuroscience Source Type: research

Tackling fear: Beyond associative memory activation as the only determinant of fear responding
Publication date: Available online 11 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Yannick Boddez, Agnes Moors, Gaëtan Mertens, Jan De HouwerAbstractFor decades already, the human fear conditioning paradigm has been used to study and develop treatments for anxiety disorders. This research is guided by theoretical assumptions that, in some cases indirectly, stem from the tradition of association formation models (e.g., the Rescorla-Wagner model). We argue that one of these assumptions – fear responding as a monotonic function of the associative activation of aversive memory representati...
Source: Neuroscience and Biobehavioral Reviews - February 12, 2020 Category: Neuroscience Source Type: research

Do the effects of cannabis on the hippocampus and striatum increase risk for psychosis?
Publication date: Available online 11 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Y. Daniju, M.G. Bossong, K. Brandt, P. AllenAbstractCannabis use is associated with increased risk of psychotic symptoms and in a small number of cases it can lead to psychoses. This review examines the neurobiological mechanisms that mediate the link between cannabis use and psychosis risk. We use an established preclinical model of psychosis, the methylazoxymethanol acetate (MAM) rodent model, as a framework to examine if psychosis risk in some cannabis users is mediated by the effects of cannabis on the hippocam...
Source: Neuroscience and Biobehavioral Reviews - February 12, 2020 Category: Neuroscience Source Type: research

Why is Music Therapeutic for Neurological Disorders? The Therapeutic Music Capacities Model
Publication date: Available online 9 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Olivia Brancatisano, Amee Baird, William Forde ThompsonAbstractMusic has cognitive, psychosocial, behavioral and motor benefits for people with neurological disorders such as dementia, stroke, Parkinson’s disease and Autism Spectrum Disorder. Here we discuss seven properties or ‘capacities’ of music that interact with brain function and contribute to its therapeutic value. Specifically, in its various forms, music can be engaging, emotional, physical, personal, social and persuasive, and it promote...
Source: Neuroscience and Biobehavioral Reviews - February 10, 2020 Category: Neuroscience Source Type: research

On the pathophysiology and treatment of akinetic mutism
Publication date: Available online 7 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Hisse Arnts, Willemijn S. van Erp, Jan C.M. Lavrijsen, Simon van Gaal, Henk J. Groenewegen, Pepijn van den MunckhofAbstractAkinetic mutism (AM) is a rare neurological disorder characterized by the presence of an intact level of consciousness and sensorimotor capacity, but with a simultaneous decrease in goal-directed behavior and emotions. Patients are in a wakeful state of profound apathy, seemingly indifferent to pain, thirst, or hunger. It represents the far end within the spectrum of disorders of diminished moti...
Source: Neuroscience and Biobehavioral Reviews - February 9, 2020 Category: Neuroscience Source Type: research

Role of cyclic nucleotides and their downstream signaling cascades in memory function: being at the right time at the right spot
Publication date: Available online 7 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Elentina K. Argyrousi, Pim R.A. Heckman, Jos PrickaertsAbstractA plethora of studies indicate the important role of cAMP and cGMP cascades in neuronal plasticity and memory function. As a result, altered cyclic nucleotide signaling has been implicated in the pathophysiology of mnemonic dysfunction encountered in several diseases. In the present review we provide a wide overview of studies regarding the involvement of cyclic nucleotides, as well as their upstream and downstream molecules, in physiological and patholo...
Source: Neuroscience and Biobehavioral Reviews - February 9, 2020 Category: Neuroscience Source Type: research

Neurodevelopmental pathways in bipolar disorder
Publication date: Available online 5 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Stefan Kloiber, Joshua D. Rosenblat, Muhammad I. Husain, Abigail Ortiz, Michael Berk, Joao Quevedo, Eduard Vieta, Michael Maes, Boris Birmaher, Jair C. Soares, Andre F. CarvalhoAbstractAberrations in neurodevelopmental trajectories have been implicated in the neurobiology of several mental disorders and evidence indicates a pathophysiological and genetic overlap of schizophrenia and bipolar disorder (BD). In this narrative review, we summarize findings related to developmental and perinatal factors as well as epidem...
Source: Neuroscience and Biobehavioral Reviews - February 6, 2020 Category: Neuroscience Source Type: research

Gut microbiota differences between healthy older adults and individuals with Parkinson’s disease: A systematic review
Publication date: Available online 4 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Nathan D. Nuzum, Amy Loughman, Ewa A. Szymlek-Gay, Ashlee Hendy, Wei-Peng Teo, Helen MacphersonAbstractThe ‘Dual Hit’ hypothesis, stating that Parkinson’s disease (PD) begins via olfactory pathways and the gut, and the gastrointestinal symptoms PD individuals face, have largely driven the interest of the gut’s involvement in PD. Studies have since observed gut microbiota differences between PD groups and controls, with these alterations potentially relating to PD pathophysiology. However, dif...
Source: Neuroscience and Biobehavioral Reviews - February 6, 2020 Category: Neuroscience Source Type: research

Respiratory Regulation & Interactions with Neuro-Cognitive Circuitry
Publication date: Available online 3 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Vojislav Maric, Dhakshin Ramanathan, Jyoti MishraAbstractIt is increasingly being recognized that active control of breathing - a key aspect of ancient Vedic meditative practices, can relieve stress and anxiety and improve cognition. However, the underlying mechanisms of respiratory modulation of neurophysiology are just beginning to be elucidated. Research shows that brainstem circuits involved in the motor control of respiration receive input from and can directly modulate activity in subcortical circuits, affecti...
Source: Neuroscience and Biobehavioral Reviews - February 4, 2020 Category: Neuroscience Source Type: research

Accelerated aging in bipolar disorder: a comprehensive review of molecular findings and their clinical implications
Publication date: Available online 1 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Gabriel R. Fries, Madeline J. Zamzow, Taylor Andrews, Omar Pink, Giselli Scaini, Joao QuevedoAbstractBipolar disorder (BD) has been associated with clinical signs of accelerated aging, which potentially underlies its association with several age-related medical conditions, such as hypertension, metabolic imbalances, dementia, and cancer. This paper aims to comprehensively review evidence of biological aging in BD and explore findings and controversies related to common biological clocks in patients, including telome...
Source: Neuroscience and Biobehavioral Reviews - February 3, 2020 Category: Neuroscience Source Type: research

How does the brain learn environmental structure? Ten core principles for understanding the neurocognitive mechanisms of statistical learning
Publication date: Available online 1 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Christopher M. ConwayAbstractDespite a growing body of research devoted to the study of how humans encode environmental patterns, there is still no clear consensus about the nature of the neurocognitive mechanisms underpinning statistical learning nor what factors constrain or promote its emergence across individuals, species, and learning situations. Based on a review of research examining the roles of input modality and domain, input structure and complexity, attention, neuroanatomical bases, ontogeny, and phyloge...
Source: Neuroscience and Biobehavioral Reviews - February 3, 2020 Category: Neuroscience Source Type: research

Developing an understanding of skin picking in people with Prader-Willi syndrome: a structured literature review and re-analysis of existing data
Publication date: Available online 1 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Joyce Whittington, Anthony HollandAbstractA search of the PubMed and Web of Science databases for articles on skin picking in PWS was undertaken identifying case studies; trials of specific treatments; and descriptions of when skin picking occurs, what sites are chosen, and what initiates and sustains this behaviour. Published papers have also considered how skin picking might link to the PWS genotype and whether it is best considered to be part of the repetitive and ritualistic behaviours characteristic of the synd...
Source: Neuroscience and Biobehavioral Reviews - February 3, 2020 Category: Neuroscience Source Type: research

Modelling the effects of ongoing alpha activity on visual perception: The oscillation-based probability of response
Publication date: Available online 2 February 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Agnese Zazio, Marco Schreiber, Carlo Miniussi, Marta BortolettoAbstractSubstantial evidence has shown that ongoing neural activity significantly contributes to how the brain responds to upcoming stimuli. In visual perception, a considerable portion of trial-to-trial variability can be accounted for by prestimulus magneto/electroencephalographic (M/EEG) alpha oscillations, which play an inhibitory function by means of cross-frequency interactions with gamma-band oscillations. Despite the fundamental theories on the r...
Source: Neuroscience and Biobehavioral Reviews - February 3, 2020 Category: Neuroscience Source Type: research

The neuroscience of sadness: A multidisciplinary synthesis and collaborative review
Publication date: April 2020Source: Neuroscience & Biobehavioral Reviews, Volume 111Author(s): Juan A. Arias, Claire Williams, Rashmi Raghvani, Moji Aghajani, Sandra Baez, Catherine Belzung, Linda Booij, Geraldo Busatto, Julian Chiarella, Cynthia HY Fu, Agustin Ibanez, Belinda J. Liddell, Leroy Lowe, Brenda W.J.H. Penninx, Pedro Rosa, Andrew H. KempAbstractSadness is typically characterized by raised inner eyebrows, lowered corners of the mouth, reduced walking speed, and slumped posture. Ancient subcortical circuitry provides a neuroanatomical foundation, extending from dorsal periaqueductal grey to subgenual anterior...
Source: Neuroscience and Biobehavioral Reviews - February 3, 2020 Category: Neuroscience Source Type: research

Genes and environment in attachment
Publication date: Available online 31 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Angelo Picardi, Eugenia Giuliani, Antonella GigantescoAbstractIn the last two decades, there has been increasing research interest in disentangling the contribution of genetic and environmental factors to individual differences in attachment, and in identifying the genes involved in shaping attachment. Twin studies suggest that as attachment changes during the course of development, genetic factors may play a progressively more important role, while shared environmental effects might decrease. However, most of this ...
Source: Neuroscience and Biobehavioral Reviews - February 1, 2020 Category: Neuroscience Source Type: research

A place for behavior in neuroscience: Recent advances in behavioral neuroscience
Publication date: Available online 30 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): F. Scott Hall, Elena Choleris (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - January 31, 2020 Category: Neuroscience Source Type: research

Revisiting the validity of the mouse tail suspension test: Systematic review and meta-analysis of the effects of prototypic antidepressants
Publication date: Available online 30 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Yelena Stukalin, Anat Lan, Haim EinatAbstractAnimal models in neuropsychiatric research need validation. One way to address external validity is systematic reviews and meta-analyses. The present study presents a meta-analysis of the effects of antidepressants in the mouse tail suspension test (TST).A PubMed search identified studies that examined imipramine and fluoxetine effects in the TST. Inclusion criteria were testing in the light phase; trial duration was six minutes; immobility time scored 6 or (last) 4&thins...
Source: Neuroscience and Biobehavioral Reviews - January 31, 2020 Category: Neuroscience Source Type: research

Modality-specific overlaps in brain structure and function in Obsessive-compulsive disorder: multimodal meta-analysis of case-control MRI studies
Publication date: Available online 30 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Maria Picó-Pérez, Pedro Silva Moreira, Vanessa de Melo Ferreira, Joaquim Radua, David Mataix-Cols, Nuno Sousa, Carles Soriano-Mas, Pedro MorgadoAbstractNeuroimaging research has shown that patients with obsessive-compulsive disorder (OCD) may present brain structural and functional alterations, but the results across imaging modalities and task paradigms are difficult to reconcile. Are the same brain systems that are structurally different in OCD patients also involved in executive function and emotion...
Source: Neuroscience and Biobehavioral Reviews - January 31, 2020 Category: Neuroscience Source Type: research

The Neuroscience of Sadness: A Multidisciplinary Synthesis and Collaborative Review for the Human Affectome Project
Publication date: Available online 27 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Juan A. Arias, Claire Williams, Rashmi Raghvani, Moji Aghajani, Sandra Baez, Catherine Belzung, Linda Booij, Geraldo Busatto, Julian Chiarella, Cynthia HY Fu, Agustin Ibanez, Belinda J. Liddell, Leroy Lowe, Brenda W.J.H. Penninx, Pedro Rosa, Andrew H. KempAbstractSadness is typically characterized by raised inner eyebrows, lowered corners of the mouth, reduced walking speed, and slumped posture. Ancient subcortical circuitry provides a neuroanatomical foundation, extending from dorsal periaqueductal grey to subgenua...
Source: Neuroscience and Biobehavioral Reviews - January 29, 2020 Category: Neuroscience Source Type: research

Challenges in the comparative study of empathy and related phenomena in animals
Publication date: Available online 27 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): J.E.C. Adriaense, S.E. Koski, L. Huber, C. LammAbstractThe aim of this review is to discuss recent arguments and findings in the comparative study of empathy. Based on a multidisciplinary approach including psychology and ethology, we review the non-human animal literature concerning theoretical frameworks, methodology, and research outcomes. One specific objective is to highlight discrepancies between theory and empirical findings, and to discuss ambiguities present in current data and their interpretation. In part...
Source: Neuroscience and Biobehavioral Reviews - January 29, 2020 Category: Neuroscience Source Type: research

Effects of Maternal Stress and Nutrient Restriction during Gestation on Offspring Neuroanatomy in Humans
Publication date: Available online 28 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Katja Franke, Bea van den Bergh, Susanne R. de Rooij, Nasim Kroegel, Peter W. Nathanielsz, Florian Rakers, Tessa J. Roseboom, Otto.W. Witte, Matthias SchwabAbstractCognitive and mental health are major determinants of quality of life, allowing integration into society at all ages. Human epidemiological and animal studies indicate that in addition to genetic factors and lifestyle, prenatal environmental influences may program neuropsychiatric disorders in later life. While several human studies have examined the effe...
Source: Neuroscience and Biobehavioral Reviews - January 29, 2020 Category: Neuroscience Source Type: research

Neuroimaging the Consciousness of Self: Review, and Conceptual-Methodological Framework
Publication date: Available online 26 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Paul Frewen, Matthias L. Schroeter, Giuseppe Riva, Pietro Cipresso, Beth Fairfield, Caterina Padulo, Andrew Haddon Kemp, Lena Palaniyappan, Mayowa Owolabi, Kwabena Kusi-Mensah, Maryna Polyakova, Nick Fehertoi, Wendy D’Andrea, Leroy Lowe, Georg NorthoffAbstractWe review neuroimaging research investigating self-referential processing (SRP), that is, how we respond to stimuli that reference ourselves, prefaced by a lexical-thematic analysis of words indicative of “self-feelings”. We consider SRP as oc...
Source: Neuroscience and Biobehavioral Reviews - January 28, 2020 Category: Neuroscience Source Type: research

Animal affect and decision-making
Publication date: Available online 25 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Michael Mendl, Elizabeth S. PaulAbstractThe scientific study of animal affect (emotion) is an area of growing interest. Whilst research on mechanism and causation has predominated, the study of function is less advanced. This is not due to a lack of hypotheses; in both humans and animals, affective states are frequently proposed to play a pivotal role in coordinating adaptive responses and decisions. However, exactly how they might do this (what processes might implement this function) is often left rather vague. He...
Source: Neuroscience and Biobehavioral Reviews - January 26, 2020 Category: Neuroscience Source Type: research

Emotional expressions in human and non-human great apes
Publication date: Available online 25 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Mariska E. Kret, Eliska Prochazkova, Elisabeth H.M. Sterck, Zanna ClayAbstractHumans and great apes are highly social species, and encounter conspecifics throughout their daily lives. During social interactions, they exchange information about their emotional states via expressions through different modalities including the face, body and voice. In this regard, their capacity to express emotions, intentionally or unintentionally, is crucial for them to successfully navigate their social worlds and to bond with group...
Source: Neuroscience and Biobehavioral Reviews - January 26, 2020 Category: Neuroscience Source Type: research

Earlier versus later cognitive event-related potentials (ERPs) in Attention-Deficit/Hyperactivity Disorder (ADHD): A meta-analysis
Publication date: Available online 25 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Anna Kaiser, Pascal-M. Aggensteiner, Sarah Baumeister, Nathalie E. Holz, Tobias Banaschewski, Daniel BrandeisAbstractThe current meta-analysis summarizes relevant literature on earlier (P100, N100, P200, N200, ERN/Ne) versus later (P300, Pe, CNV) cognitive Event-Related Potential (ERP) differences between children, adolescents, and adults with Attention-Deficit/Hyperactivity Disorder (ADHD) and without ADHD (non-ADHD). Furthermore, the heterogeneity in previous research is addressed by analyzing potentially relevant...
Source: Neuroscience and Biobehavioral Reviews - January 26, 2020 Category: Neuroscience Source Type: research

Intracerebral seeding of amyloid-β and tau pathology in mice: factors underlying prion-like spreading and comparisons with α-synuclein
Publication date: Available online 26 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Brendan B. McAllister, Sean G. Lacoursiere, Robert J. Sutherland, Majid H. MohajeraniAbstractAlzheimer’s disease (AD) is characterized neuropathologically by progressive neurodegeneration and by the presence of amyloid plaques and neurofibrillary tangles. These plaques and tangles are composed, respectively, of amyloid-beta (Aβ) and tau proteins. While long recognized as hallmarks of AD, it remains unclear what causes the formation of these insoluble deposits. One theory holds that prion-like templated mi...
Source: Neuroscience and Biobehavioral Reviews - January 26, 2020 Category: Neuroscience Source Type: research

Demographic and clinical features as predictors of clozapine response in patients with schizophrenia spectrum disorders: a systematic review and meta-analysis
ConclusionThe results of our meta-analyses suggest that three baseline demographic and clinical features are associated with better clozapine response, i.e. relatively young age, few negative symptoms and paranoid schizophrenia subtype. These variables may be taken into account by clinicians who consider treating a specific patient with CLZ. Keywords: Clozapine, response, schizophrenia spectrum disorders, prediction (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - January 25, 2020 Category: Neuroscience Source Type: research

Social Semantics: The role of conceptual knowledge and cognitive control in a neurobiological model of the social brain
Publication date: Available online 23 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Richard J. Binney, Richard RamseyAbstractResearch in social neuroscience has primarily focused on carving up cognition into distinct pieces, as a function of mental process, neural network or social behaviour, while the need for unifying models that span multiple social phenomena has been relatively neglected. Here we present a novel framework that treats social cognition as a case of semantic cognition, which provides a neurobiologically constrained and generalizable framework, with clear, testable predictions rega...
Source: Neuroscience and Biobehavioral Reviews - January 25, 2020 Category: Neuroscience Source Type: research

The nuts and bolts of animal emotion
Publication date: Available online 23 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): L. Kremer, S.E.J. Klein Holkenborg, I.S. Reimert, J.E. Bolhuis, L.E. WebbAbstractKremer, L., S.E.J. Klein Holkenborg, I.S. Reimert, J.E. Bolhuis, L.E. Webb. The nut and bolts of animal emotion. NEUROSCI BIOBEHAV REV X, XXX-XXX, 2019. - The study of animal emotion, as with its human equivalent, can be confusing due to the complicated and inconsistent use of terminology, and the number of interlinked fields and topics it encompasses. With this review, we aim to provide an up-to-date and, to the best of our knowledge, ...
Source: Neuroscience and Biobehavioral Reviews - January 25, 2020 Category: Neuroscience Source Type: research

Disentangling the molecular mechanisms of multiple sclerosis: the contribution of twin studies
Publication date: Available online 21 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): M.C. Buscarinu, A. Fornasiero, M. Ferraldeschi, S. Romano, R. Reniè, E. Morena, C. Romano, G. Pellicciari, A.C. Landi, C. Fagnani, M. Salvetti, G. RistoriAbstractTwin studies of disease concordance are useful to weight the relative contribution of genetic and environmental factors to the cause of common complex disorders. In multiple sclerosis (MS) different twinning rates from geographic areas at different prevalence suggested that heritable and non-heritable factors contribute in different proportions and w...
Source: Neuroscience and Biobehavioral Reviews - January 23, 2020 Category: Neuroscience Source Type: research

Mapping Sign-Tracking and Goal-Tracking onto Human Behaviors
Publication date: Available online 20 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Janna M. Colaizzi, Shelly B. Flagel, Michelle A. Joyner, Ashley N. Gearhardt, Jennifer L. Stewart, Martin P. PaulusAbstractAs evidenced through classic Pavlovian learning mechanisms, environmental cues can become incentivized and influence behavior. These stimulus-outcome associations are relevant in everyday life but may be particularly important for the development of impulse control disorders including addiction. Rodent studies have elucidated specific learning profiles termed ‘sign-tracking’ and &lsq...
Source: Neuroscience and Biobehavioral Reviews - January 22, 2020 Category: Neuroscience Source Type: research

Pulvino-cortical interaction: an integrative role in the control of attention
Publication date: Available online 20 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Alexia Bourgeois, Carole Guedj, Emmanuel Carrera, Patrik VuilleumierAbstractSelective attention is a fundamental cognitive function that guides behavior by selecting and prioritizing salient or relevant sensory information of our environment. Despite early evidence and theoretical proposal pointing to an implication of thalamic control in attention, most studies in the past two decades focused on cortical substrates, largely ignoring the contribution of subcortical regions as well as cortico-subcortical interactions...
Source: Neuroscience and Biobehavioral Reviews - January 22, 2020 Category: Neuroscience Source Type: research

The neuroethology of spontaneous mimicry and emotional contagion in human and non-human animals
In conclusion, this review proposes a bottom-up, multidisciplinary approach to the study of spontaneous mimicry that accounts for the evolutionary continuity linking non-human and human animals. (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - January 22, 2020 Category: Neuroscience Source Type: research

Overlapping mechanisms linking insulin resistance with cognition and neuroprogression in bipolar disorder
Publication date: Available online 21 January 2020Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Ari B. Cuperfain, James L. Kennedy, Vanessa F. GoncalvesAbstractCognitive impairment is highly prevalent in the progression of both diabetes mellitus and bipolar disorder. The relationship between insulin resistance in diabetes and the risk of developing major neurocognitive disorders such as Alzheimer’s disease has been well described. Insulin resistance and the associated metabolic deficiencies lead to biochemical alteration which hasten neurodegeneration and subsequent cognitive impairment. For bipolar diso...
Source: Neuroscience and Biobehavioral Reviews - January 22, 2020 Category: Neuroscience Source Type: research