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Condition: Endocarditis

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Total 767 results found since Jan 2013.

Carotid artery disease and perioperative stroke risk after surgical aortic valve replacement: A nationwide inpatient sample analysis
In conclusion, perioperative stroke risk has remained more or less constant despite advancements in surgical techniques with risk having gone up in patients <65years of age. CS and cerebral arterial occlusion significantly increase stroke risk following SAVR. Improved patient selection with pre-operative risk stratification and institution of preventive strategies are necessary to improve operative outcomes following SAVR.
Source: Journal of Clinical Neuroscience - June 29, 2017 Category: Neuroscience Source Type: research

Body mass index and fatal stroke in young adults: a national study
This study aimed to determine the body mass index (BMI) of fatal stroke cases amongst young adults, their clinical characteristics and the association with BMI with risk factors. All cases aged 15-44 years where death was attributed to stroke for whom BMI was available were retrieved from the National Coronial Information System (1/1/2009-31/12/2016). 179 cases were identified: haemorrhagic (165), ischaemic (5), thrombotic (6), mycotic (3), embolic (0). Proportions in each BMI category were: underweight (5.6%), normal weight (37.4%), overweight (27.4%), obese (29.6%). There was a significant linear trend in the proportion ...
Source: Journal of Forensic and Legal Medicine - February 15, 2019 Category: Forensic Medicine Source Type: research

Stroke in malignancy: complexities of diagnosis and management: a case report
ConclusionsThis case highlights the importance of having a high threshold of suspicion for malignancy as a cause of stroke.
Source: Journal of Medical Case Reports - August 19, 2019 Category: General Medicine Source Type: research

Enterobacter Cloacae Endocarditis Presenting as an Ischemic Stroke (P2.279)
CONCLUSIONS: This is the first case which demonstrates that ischemic stroke can be the presenting clinical event of E. cloacae endocarditis. Clinicians who provide acute care to patients with stroke should be aware of this rare cause of embolic brain infarction. Our case shows that early diagnosis of E. cloacae endocarditis and appropriate medical management can promote full neurological recovery in these patients. Disclosure: Dr. mannel has nothing to disclose. Dr. Silliman has received personal compensation for activities with Biogen Idec, and Teva Neuroscience as a consultant and/or speaker. Dr. Silliman has received re...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mannel, R., Silliman, S. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research

Complex decision-making in stroke: preoperative mechanical thrombectomy of septic embolus for emergency cardiac valve surgery
We report a case of cardioembolic stroke in a patient with enterococcal endocarditis, with National Institutes of Health Stroke Scale score of 3. A middle-aged patient with bacterial endocarditis exhibited mild intermittent left hemiparesis and dysarthria in the setting of severe aortic insufficiency requiring urgent aortic valve replacement. Cerebrovascular imaging revealed a partially occlusive thrombus in the M1 segment of the right middle cerebral artery, which became symptomatic during relative hypotension. Given the expected hypotension during the urgently needed aortic valve replacement, there was a significant risk...
Source: Journal of NeuroInterventional Surgery - November 13, 2015 Category: Neurosurgery Authors: Ladner, T. R., Davis, B. J., He, L., Kirshner, H. S., Froehler, M. T., Mocco, J. Tags: Electronic pages Source Type: research

Clinical Presentation and Multi-Parametric Screening Surrogates of Ischemic Stroke Patients Suffering from Infective Endocarditis
Conclusions: IE in stroke patients is associated with worse clinical outcome, complicated by intravenously applied thrombolysis, and therefore needs to be screened during the early phase of hospitalization. Increased serum levels of CRP and leukocyte count in combination with an increased body temperature or abnormal cardiac murmurs should entail rapid initiation of further diagnostics, that is, transoesophageal echocardiography.Cerebrovasc Dis 2016;41:60-67
Source: Cerebrovascular Diseases - December 15, 2015 Category: Neurology Source Type: research

A review of the role of anticoagulation for patients with infective endocarditis and embolic stroke
Key Clinical Message Stroke is a common embolic complication of infective endocarditis. The most important treatment to prevent stroke in endocarditis is the initiation of antibiotic therapy. It is unclear whether the initiation of de novo anticoagulation (i.e, warfarin) in patients with infective endocarditis is beneficial, since there are no large or randomized controlled trials in this area. However, this case report suggests, despite the limited evidence, that anticoagulation in this patient caused no harm and could suggest a hint of possible benefit. Stroke is a common embolic complication of infective endocarditis. ...
Source: Clinical Case Reports - April 12, 2016 Category: Journals (General) Authors: Arfah Hazel Preston, Stefan Williams, Judy Archer Tags: Case Report Source Type: research

When the heart rules the head: ischaemic stroke and intracerebral haemorrhage complicating infective endocarditis.
Abstract Sir William Osler meticulously described the clinical manifestations of infective endocarditis in 1885, concluding that: 'few diseases present greater difficulties in the way of diagnosis … which in many cases are practically insurmountable'. Even with modern investigation techniques, diagnosing infective endocarditis can be hugely challenging, yet is critically important in patients presenting with stroke (both cerebral infarction and intracranial haemorrhage), its commonest neurological complication. In ischaemic stroke, intravenous thrombolysis carries an unacceptably high risk of intracranial haemor...
Source: Practical Neurology - January 2, 2017 Category: Neurology Authors: Jiad E, Gill SK, Krutikov M, Turner D, Parkinson MH, Curtis C, Werring DJ Tags: Pract Neurol Source Type: research

Clot Histopathology in Ischemic Stroke with Infective Endocarditis.
CONCLUSION: Detailed morphological and histopathological analysis of EVT-retrieved clots including Gram staining can assist in etiological classification of the clot. Understanding the composition of the clot may be of clinical value in early diagnostics and mapping treatment planning in IE. PMID: 30867075 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - March 13, 2019 Category: Neurology Authors: Bhaskar S, Saab J, Cappelen-Smith C, Killingsworth M, Wu XJ, Cheung A, Manning N, Aouad P, McDougall A, Hodgkinson S, Cordato D Tags: Can J Neurol Sci Source Type: research

Psychostimulant Use and Fatal Stroke in Young Adults.
Abstract Psychostimulant use is associated with increased stroke risk. To determine the proportion of psychostimulant users among fatal strokes in young adults (15-44 years), all cases were retrieved from the National Coronial Information System (1/1/2009-31/12/2016). A total of 279 cases were identified: hemorrhagic (259), ischemic (8), thrombotic (8), and mycotic (4). Fifty (17.9%) were identified as psychostimulant users. Psychostimulants in blood were detected in 37/45 where toxicology was available, predominantly methamphetamine (32/45). Hemorrhagic strokes in the psychostimulant group were more likely to be...
Source: Journal of Forensic Sciences - April 1, 2019 Category: Forensic Medicine Authors: Darke S, Duflou J, Kaye S, Farrell M, Lappin J Tags: J Forensic Sci Source Type: research

Antithrombotic Therapy for Stroke Patients with Cardiovascular Disease
Semin Neurol DOI: 10.1055/s-0041-1726331Prevention of ischemic stroke relies on the use of antithrombotic medications comprising antiplatelet agents and anticoagulation. Stroke risk is particularly high in patients with cardiovascular disease. This review will focus on the role of antithrombotic therapies in the context of different types of cardiovascular disease. We will discuss oral antiplatelet medications and both IV and parental anticoagulants. Different kinds of cardiovascular disease contribute to stroke via distinct pathophysiological mechanisms, and the optimal treatment for each varies accordingly. We will explo...
Source: Seminars in Neurology - April 13, 2021 Category: Neurology Authors: Gusdon, Aaron M. Farrokh, Salia Grotta, James C. Tags: Review Article Source Type: research

Intravenous thrombolysis is unsafe in stroke due to infective endocarditis
We describe a patient with occult endocarditis who was treated with thrombolysis for acute stroke and review other cases reported in the literature.
Source: Internal Medicine Journal - February 17, 2014 Category: Internal Medicine Authors: W. J. Brownlee, N. E. Anderson, P. A. Barber Tags: Brief Communication Source Type: research

Pathological features of intracardiac bacterial vegetation and intracranial arterial thrombus due to infective endocarditis in a stroke patient
We report herein on autopsy and pathological findings for IE-related stroke in a patient receiving hemodialysis.
Source: Journal of the Neurological Sciences - October 17, 2014 Category: Neurology Authors: Takashi Shimoyama, Naoki Saji, Junichi Uemura, Kensaku Shibazaki, Hirotake Nishimura, Kazumi Kimura Tags: Letter to the Editor Source Type: research

Catastrophic Intracranial Hemorrhages after IV tPA in a Patient with Insidious Onset of Fever and Back Pain
We present a patient who had a history of recent and persistent fever, an acute ischemic stroke treated with intravenous tissue plasminogen activator (IV tPA), and severe, multifocal intracerebral hemorrhage as a complication of tPA treatment. Suspected infective endocarditis in a stroke patient should most likely be considered a contraindication to IV tPA.
Source: Journal of Stroke and Cerebrovascular Diseases - January 21, 2016 Category: Neurology Authors: Steven Tversky, Richard B. Libman, Evan R. Schloss, Rohan Arora, Anand V. Patel, Elliot J. Salamon, Paul Wright, Jeffrey M. Katz Tags: Case Studies Source Type: research

Thiamine Deficiency While on Total Parenteral Nutrition Mimicking Acute Stroke: A Case Report (P3.217)
CONCLUSIONS: Thiamine deficiency mimicking stroke while on total parenteral nutrition has been rarely documented. Recognition of this syndrome is critical as prompt treatment may reverse symptoms.Disclosure: Dr. Parker has nothing to disclose. Dr. Marafie has nothing to disclose. Dr. Wolf has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Parker, A., Marafie, D., Wolf, V. Tags: Neurocritical Care: Clinical Science and Therapeutics Source Type: research