Extranodal Rosai-Dorfman disease involving pulmonary artery detected by 68Ga-FAPI PET/CT and fused 68Ga-FAPI PET/MRI
(Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - June 15, 2023 Category: Nuclear Medicine Source Type: research
A primary Rosai-Dorfman-Destombes disease of the scalp: case report and literature review
ConclusionsRDD of the scalp is rare. Surgical incision can cure the lesion but it may become infected because of increased lymphocytic infiltration. Early diagnosis and differential diagnosis of RDD are necessary. For treatment, individualized therapy is critical to patient prognosis. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - June 8, 2023 Category: Neurology Source Type: research
Histiocytosis
Med Clin (Barc). 2023 May 30:S0025-7753(23)00220-8. doi: 10.1016/j.medcli.2023.05.001. Online ahead of print.ABSTRACTHistiocytosis is a group of rare diseases characterized by inflammation and accumulation of cells derived from monocytes and macrophages in different tissues. The symptoms are highly variable, from mild forms with involvement of a single organ to severe multisystem forms that can be life compromising. The diagnosis of histiocytosis is based on the clinic, radiological findings and pathological anatomy. A biopsy of the affected tissue is recommended in all cases as it may have therapeutic implications. During...
Source: Medicina Clinica - June 1, 2023 Category: General Medicine Authors: Gemma Rocamora-Blanch Fina Climent Xavier Solanich Source Type: research
Testicular Rosai-Dorfman disease clonally related to CMML - Case report and literature review
CONCLUSION: These observations support classifying RDD as a neoplasm that can be clonally related to myeloid neoplasms.PMID:37216748 | DOI:10.1016/j.prp.2023.154548 (Source: Cell Research)
Source: Cell Research - May 22, 2023 Category: Cytology Authors: August Fiegl Stefan Dirnhofer Darius Juskevicius Branislav Zagrapan Susanne Dertinger Andreas B ösl Stella Milos J ürgen Brunner Franz Bertolini Felix A Offner Source Type: research
Testicular Rosai-Dorfman disease clonally related to CMML - Case report and literature review
CONCLUSION: These observations support classifying RDD as a neoplasm that can be clonally related to myeloid neoplasms.PMID:37216748 | DOI:10.1016/j.prp.2023.154548 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - May 22, 2023 Category: Pathology Authors: August Fiegl Stefan Dirnhofer Darius Juskevicius Branislav Zagrapan Susanne Dertinger Andreas B ösl Stella Milos J ürgen Brunner Franz Bertolini Felix A Offner Source Type: research
Testicular Rosai-Dorfman disease clonally related to CMML - Case report and literature review
CONCLUSION: These observations support classifying RDD as a neoplasm that can be clonally related to myeloid neoplasms.PMID:37216748 | DOI:10.1016/j.prp.2023.154548 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - May 22, 2023 Category: Pathology Authors: August Fiegl Stefan Dirnhofer Darius Juskevicius Branislav Zagrapan Susanne Dertinger Andreas B ösl Stella Milos J ürgen Brunner Franz Bertolini Felix A Offner Source Type: research
Neurological Manifestations of Histiocytic Disorders
AbstractPurpose of ReviewHistiocytic disorders, including Erdheim-Chester disease (ECD), Langerhans cell histiocytosis (LCH), and Rosai-Dorfman disease (RDD), are rare neoplasms that may present with a spectrum of neurologic involvement. Diagnostic delay is common due to heterogeneity in presentation and challenging pathology.Recent FindingsRecent advances in the treatment of these diseases targeted towards mutations in the MAP kinase pathway have led to an improved prognosis in these patients with neurologic involvement.SummaryIt is critical for clinicians to have a high index of suspicion to allow for early targeted trea...
Source: Current Neurology and Neuroscience Reports - May 20, 2023 Category: Neuroscience Source Type: research
Treatment of Langerhans Cell Histiocytosis and Histiocytic Disorders: A Focus on MAPK Pathway Inhibitors
Paediatr Drugs. 2023 May 19. doi: 10.1007/s40272-023-00569-8. Online ahead of print.ABSTRACTHistiocytic disorders are rare diseases defined by the clonal accumulation of a macrophage or dendritic cell origin. These disorders include Langerhans cell histiocytosis, Erdheim-Chester disease, juvenile xanthogranuloma, malignant histiocytoses, and Rosai-Dorfman-Destombes disease. These histiocytic disorders are a diverse group of disorders with different presentations, management, and prognosis. This review focuses on these histiocytic disorders and the role of pathological ERK signaling due to somatic mutations in the mitoge...
Source: Paediatric Drugs - May 19, 2023 Category: Pediatrics Authors: Ashley V Geerlinks Oussama Abla Source Type: research
Treatment of Langerhans Cell Histiocytosis and Histiocytic Disorders: A Focus on MAPK Pathway Inhibitors
Paediatr Drugs. 2023 May 19. doi: 10.1007/s40272-023-00569-8. Online ahead of print.ABSTRACTHistiocytic disorders are rare diseases defined by the clonal accumulation of a macrophage or dendritic cell origin. These disorders include Langerhans cell histiocytosis, Erdheim-Chester disease, juvenile xanthogranuloma, malignant histiocytoses, and Rosai-Dorfman-Destombes disease. These histiocytic disorders are a diverse group of disorders with different presentations, management, and prognosis. This review focuses on these histiocytic disorders and the role of pathological ERK signaling due to somatic mutations in the mitoge...
Source: Paediatric Drugs - May 19, 2023 Category: Pediatrics Authors: Ashley V Geerlinks Oussama Abla Source Type: research
