Talk Evidence covid-19 update - dexamethosone, testing, rehabilitation after covid.
This week we're looking beyond the press release for dexamethasone, the long awaited review of antibody testing, and how well people are recovering after surviving acute covid-19. (2.36) The preprint for dexamethasone is finally out - considerably after the press release. Carl digs into it to find out how good the news actually is. (8.49) There are a couple of newly published systematic reviews on antibody testing, so we return to our testing guru Jon Deeks - professor of biostatistics at the University of Birmingham to give us an update. (23.52)Covid-19, it became apparent as the pandemic grew, was more than a respira...
Source: The BMJ Podcast - June 25, 2020 Category: General Medicine Authors: BMJ Group Source Type: podcasts

COVID-19 Q & A: Critical Care Update
COVID-19 critical care update with Maurizio Cecconi, MD, of Humanitas University in Milan, Italy, and JAMA Associate Editor Derek C. Angus, MD, MPH, of the University of Pittsburgh. Recorded June 8, 2020. Related: Management of COVID-19 Respiratory Distress (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - June 10, 2020 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Talk evidence covid-19 update - second wave and care home failings
In this episode of Talk Evidence, we'll be finding out if second waves are inevitable (or even a thing), how the UK's failure to protect it's care homes is symbolic of a neglected part of public life, and why those papers on hydroxychloroquine were retracted. This is Talk Evidence - the podcast for evidence based medicine, where research, guidance and practice are debated and demystified. Helen Macdonald, UK research editor for The BMJ, and Carl Heneghan, professor of EBM at the University of Oxford and editor of BMJ EBM, talk about some of the latest developments in the world of evidence, and what they mean. This week...
Source: The BMJ Podcast - June 8, 2020 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk evidence covid-19 update - second wave and care home failings
In this episode of Talk Evidence, we'll be finding out if second waves are inevitable (or even a thing), how the UK's failure to protect it's care homes is symbolic of a neglected part of public life, and why those papers on hydroxychloroquine were retracted. This is Talk Evidence - the podcast for evidence based medicine, where research, guidance and practice are debated and demystified. Helen Macdonald, UK research editor for The BMJ, and Carl Heneghan, professor of EBM at the University of Oxford and editor of BMJ EBM, talk about some of the latest developments in the world of evidence, and what they mean. This week...
Source: The BMJ Podcast - June 8, 2020 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk evidence covid-19 update - second wave and care home failings
In this episode of Talk Evidence, we'll be finding out if second waves are inevitable (or even a thing), how the UK's failure to protect it's care homes is symbolic of a neglected part of public life, and why those papers on hydroxychloroquine were retracted. This is Talk Evidence - the podcast for evidence based medicine, where research, guidance and practice are debated and demystified. Helen Macdonald, UK research editor for The BMJ, and Carl Heneghan, professor of EBM at the University of Oxford and editor of BMJ EBM, talk about some of the latest developments in the world of evidence, and what they mean. This week:...
Source: The BMJ Podcast - June 8, 2020 Category: General Medicine Authors: BMJ Group Source Type: podcasts

TWiV 622: Nonhuman primate model for COVID-19 with Emmie de Wit
Emmie de Wit joins TWiV to explain her work on the pathogenesis of infection with SARS-CoV-2 in rhesus macaques, including studies on remdesivir and vaccine candidate. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Emmie de Wit Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Respiratory disease in macaques inoculated with SARS-CoV-2 (Nature) Clinical benefit of remdesivir in SARS-CoV-2 infected macaques (bioRxiv) Remdesivir for MERS-CoV infection in macaques (PNAS) ChAdOX1 vaccination for SARS-CoV-2 in macaques (bioRxiv) Image credit Timestamp...
Source: This Week in Virology - MP3 Edition - June 2, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

SCCM Pod-414 COVID-19 VIRUS Registry Aims to Identify Effective Treatment Strategies
Discovery, the Critical Care Research Network's Viral Infection and Respiratory Illness Universal Study creates a real-time COVID-19 registry of current ICU and hospital care patterns. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - May 7, 2020 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 609: A coronavirus chronology with Susan Weiss
Susan Weiss recalls some of her 40 years of research on coronaviruses, including mouse hepatitis virus, MERS-CoV, and now SARS-CoV-2. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Susan Weiss Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Coronaviruses by Susan Weiss (YouTube) Forty years with coronaviruses (JEM) No credible evidence that SARS-CoV-2 came from a lab (Emerg Micr Infect) CoV and antagonism of RNAse L (mBio) Exoribonuclease needed for MHV innate antagonism (J Virol) RNAse L and ADAR...
Source: This Week in Virology - MP3 Edition - May 3, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Factors that influence whether healthcare workers follow infection prevention and control guidelines for respiratory infectious diseases
COVID-19 has spread quickly, and Cochrane is producing a series of rapid reviews of relevant evidence to help decision makers. One of these looks at the views of healthcare workers on infection prevention and control guidelines, and we asked lead author, Catherine Houghton from the National University of Ireland in Galway to describe the key findings, published in April 2020. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - April 21, 2020 Category: General Medicine Authors: Cochrane Source Type: podcasts

TWiV 602: Coronavirus immunology with Stanley Perlman
Stanley Perlman joins TWiV to discuss immune responses to coronaviruses, including seasonal CoV, MERS, SARS, and SARS-CoV-2, including prospects for a vaccine. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Guest: Stanley Perlman Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Perlman Laboratory An Iowa Caucus of Viruses (TWiV 538) Anti-SARS-CoV spike IgG and acute lung injury (JCI Insight) T cell responses to respiratory CoV (Immunol Res) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions an...
Source: This Week in Virology - MP3 Edition - April 16, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss
For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give you some insight into these issues. This week: (2.24) - Hydroxychloroquinine/chloroquinine - Robin Ferner, honorary professor of clinical pharmacology at the University of Birmingham explains why is it a potential therapeutic for covid-19, and why is it being hyped. (12.45) - W...
Source: The BMJ Podcast - April 13, 2020 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss
For the next few months Talk Evidence is going to focus on the new corona virus pandemic. There is an enormous amount of uncertainty about the disease, what the symptoms are, fatality rate, treatment options, things we shouldn't be doing. We're going to try to get away from the headlines and talk about what we need to know - to hopefully give you some insight into these issues. This week: (2.24) - Hydroxychloroquinine/chloroquinine - Robin Ferner, honorary professor of clinical pharmacology at the University of Birmingham explains why is it a potential therapeutic for covid-19, and why is it being hyped. (12.45) - W...
Source: The BMJ Podcast - April 13, 2020 Category: General Medicine Authors: BMJ Group Source Type: podcasts

SCCM Pod-410 COVID-19 Neurologic Manifestations
Review neurologic manifestations of COVID-19 and other severe respiratory viral contagions with host Ludwig H. Lin, MD, and author Christopher P. (Source: SCCM PodCast - iCritical Care)
Source: SCCM PodCast - iCritical Care - April 8, 2020 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

TWiV 599: Coronavirus update - we need a plan
Doris Cully joins TWiV to discuss inhibition of SARS-CoV-2 in cell culture by ivermectin, followed by continuing analysis of the coronavirus pandemic caused by SARS-CoV-2 including COVID-19 in Nadia the tiger, and prediction of respiratory failure by levels of IL-6. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Guest: Doris Cully Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Ivermectin inhibits SARS-CoV-2 in cell culture (Antiviral Res) Tiger at NY zoo positive for SARS-CoV-2 (NY Times) IL-6 level predicts respiratory failure in COVID-...
Source: This Week in Virology - MP3 Edition - April 8, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts