Phytochemical Estimation and Therapeutic Amelioration of Aesculus hippocastanum L. Seeds Ethanolic Extract in Gastric Ulcer in Rats Possibly by Inhibiting Prostaglandin Synthesis
ConclusionsLCMS report confirms the presence of quercetin and rutin in AH seeds ethanolic extract. The therapeutic effect of AH seeds extract against indomethacin-induced ulcer in rat model indicated the regenerated membrane integrity, with improved cellular functions and mucus thickness. Further, improved antioxidant enzyme level would help to reduce PGE2 biosynthesis. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - April 20, 2023 Category: Internal Medicine Source Type: research
Ultrasmall nitrogen-doped Cu < sub > 0 ·92 < /sub > Co < sub > 2 ·08 < /sub > O < sub > 4 < /sub > nanocrystal-decorated cerium dioxide nanoparticles for fast and complete degradation of ranitidine via permonosulfate activation
Chemosphere. 2023 Mar 30:138527. doi: 10.1016/j.chemosphere.2023.138527. Online ahead of print.ABSTRACTA simple and efficient coagulation method was used for the rapid preparation of nitrogen-doped copper-cobalt oxide (N-Cu0.92Co2·08O4) supported on cerium dioxide (CeO2), that is, N-Cu0.92Co2·08O4@CeO2. A low concentration of N-Cu0.92Co2·08O4@CeO2 (0.15 g L-1) was shown to rapidly activate permonosulfate (PMS) (0.15 g L-1) to achieve 100% degradation of ranitidine within 10 min. A 100% degradation of ranitidine enabled by the catalyst was achieved over a wide range of pH (5.5-9.0), which could be completed within 8 min ...
Source: Chemosphere - April 1, 2023 Category: Chemistry Authors: Yunqiu Zhang Fengling Rao Xianxi Zhang Hucai Zhang Fengqin Chang Abdukader Abdukayum Zhong Jin Guangzhi Hu Source Type: research
Ultrasmall nitrogen-doped Cu < sub > 0 ·92 < /sub > Co < sub > 2 ·08 < /sub > O < sub > 4 < /sub > nanocrystal-decorated cerium dioxide nanoparticles for fast and complete degradation of ranitidine via permonosulfate activation
Chemosphere. 2023 Mar 30:138527. doi: 10.1016/j.chemosphere.2023.138527. Online ahead of print.ABSTRACTA simple and efficient coagulation method was used for the rapid preparation of nitrogen-doped copper-cobalt oxide (N-Cu0.92Co2·08O4) supported on cerium dioxide (CeO2), that is, N-Cu0.92Co2·08O4@CeO2. A low concentration of N-Cu0.92Co2·08O4@CeO2 (0.15 g L-1) was shown to rapidly activate permonosulfate (PMS) (0.15 g L-1) to achieve 100% degradation of ranitidine within 10 min. A 100% degradation of ranitidine enabled by the catalyst was achieved over a wide range of pH (5.5-9.0), which could be completed within 8 min ...
Source: Chemosphere - April 1, 2023 Category: Chemistry Authors: Yunqiu Zhang Fengling Rao Xianxi Zhang Hucai Zhang Fengqin Chang Abdukader Abdukayum Zhong Jin Guangzhi Hu Source Type: research
Ultrasmall nitrogen-doped Cu < sub > 0 ·92 < /sub > Co < sub > 2 ·08 < /sub > O < sub > 4 < /sub > nanocrystal-decorated cerium dioxide nanoparticles for fast and complete degradation of ranitidine via permonosulfate activation
Chemosphere. 2023 Mar 30;327:138527. doi: 10.1016/j.chemosphere.2023.138527. Online ahead of print.ABSTRACTA simple and efficient coagulation method was used for the rapid preparation of nitrogen-doped copper-cobalt oxide (N-Cu0.92Co2·08O4) supported on cerium dioxide (CeO2), that is, N-Cu0.92Co2·08O4@CeO2. A low concentration of N-Cu0.92Co2·08O4@CeO2 (0.15 g L-1) was shown to rapidly activate permonosulfate (PMS) (0.15 g L-1) to achieve 100% degradation of ranitidine within 10 min. A 100% degradation of ranitidine enabled by the catalyst was achieved over a wide range of pH (5.5-9.0), which could be completed within 8 ...
Source: Chemosphere - April 1, 2023 Category: Chemistry Authors: Yunqiu Zhang Fengling Rao Xianxi Zhang Hucai Zhang Fengqin Chang Abdukader Abdukayum Zhong Jin Guangzhi Hu Source Type: research
Ultrasmall nitrogen-doped Cu < sub > 0 ·92 < /sub > Co < sub > 2 ·08 < /sub > O < sub > 4 < /sub > nanocrystal-decorated cerium dioxide nanoparticles for fast and complete degradation of ranitidine via permonosulfate activation
Chemosphere. 2023 Mar 30;327:138527. doi: 10.1016/j.chemosphere.2023.138527. Online ahead of print.ABSTRACTA simple and efficient coagulation method was used for the rapid preparation of nitrogen-doped copper-cobalt oxide (N-Cu0.92Co2·08O4) supported on cerium dioxide (CeO2), that is, N-Cu0.92Co2·08O4@CeO2. A low concentration of N-Cu0.92Co2·08O4@CeO2 (0.15 g L-1) was shown to rapidly activate permonosulfate (PMS) (0.15 g L-1) to achieve 100% degradation of ranitidine within 10 min. A 100% degradation of ranitidine enabled by the catalyst was achieved over a wide range of pH (5.5-9.0), which could be completed within 8 ...
Source: Chemosphere - April 1, 2023 Category: Chemistry Authors: Yunqiu Zhang Fengling Rao Xianxi Zhang Hucai Zhang Fengqin Chang Abdukader Abdukayum Zhong Jin Guangzhi Hu Source Type: research
Interaction of drugs with gut microbiota modulators
Drug Metab Rev. 2023 Mar 31:1-25. doi: 10.1080/03602532.2023.2197178. Online ahead of print.ABSTRACTOrally administered drugs undergo four stages of absorption, distribution, metabolism, and excretion in the body. However, before being absorbed into the body, orally administered drugs contact with gut microbiota, which catalyze their metabolic reactions such as reduction, hydroxylation (including deconjugation), dehydrogenation, acetylation, etc. Although these metabolic reactions typically inactivate drugs (ranitidine, digoxin, and amlodipine), some activate them (sulfasalazine). The composition and quantity of gut microb...
Source: Drug Metabolism Reviews - March 31, 2023 Category: Drugs & Pharmacology Authors: Dong-Hyun Kim Source Type: research
Interaction of drugs with gut microbiota modulators
Drug Metab Rev. 2023 Apr 4:1-14. doi: 10.1080/03602532.2023.2197178. Online ahead of print.ABSTRACTOrally administered drugs undergo four stages of absorption, distribution, metabolism, and excretion in the body. However, before being absorbed into the body, orally administered drugs contact with gut microbiota, which catalyze their metabolic reactions such as reduction, hydroxylation (including deconjugation), dehydrogenation, acetylation, etc. Although these metabolic reactions typically inactivate drugs (ranitidine, digoxin, and amlodipine), some activate them (sulfasalazine). The composition and quantity of gut microbi...
Source: Drug Metabolism Reviews - March 31, 2023 Category: Drugs & Pharmacology Authors: Dong-Hyun Kim Source Type: research
