Anti-aquaporin-4 immunoglobulin G/anti-myelin oligodendrocyte glycoprotein immunoglobulin G double-positive paraneoplastic neurological syndrome in a patient with triple-negative breast cancer
We report a rare case of paraneoplastic neurological syndrome with dual seropositivity of anti-aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies in a 40 year-old woman with metastatic triple-negative breast cancer. She received multiple lines of anti-neoplastic treatment, including immunotherapy with pembrolizumab, as well as cytotoxic chemotherapy. Paraneoplastic meningoencephalomyelitis developed 2 years after diagnosis of breast cancer and 1 year after discontinuation of immunotherapy with pembrolizumab. She first developed longitudinally extending transverse myelitis followed by left optic neuritis and men...
Source: Clinical Breast Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Amna Siddiqui Dylan Ross Ronak H Jani Vikram C Prabhu Shelly Lo Derek A Wainwright Stasia Rouse Tamer Refaat Yirong Zhu Jigisha P Thakkar Source Type: research
Anti-aquaporin-4 immunoglobulin G/anti-myelin oligodendrocyte glycoprotein immunoglobulin G double-positive paraneoplastic neurological syndrome in a patient with triple-negative breast cancer
We report a rare case of paraneoplastic neurological syndrome with dual seropositivity of anti-aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies in a 40 year-old woman with metastatic triple-negative breast cancer. She received multiple lines of anti-neoplastic treatment, including immunotherapy with pembrolizumab, as well as cytotoxic chemotherapy. Paraneoplastic meningoencephalomyelitis developed 2 years after diagnosis of breast cancer and 1 year after discontinuation of immunotherapy with pembrolizumab. She first developed longitudinally extending transverse myelitis followed by left optic neuritis and men...
Source: Clinical Genitourinary Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Amna Siddiqui Dylan Ross Ronak H Jani Vikram C Prabhu Shelly Lo Derek A Wainwright Stasia Rouse Tamer Refaat Yirong Zhu Jigisha P Thakkar Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
Anti-aquaporin-4 immunoglobulin G/anti-myelin oligodendrocyte glycoprotein immunoglobulin G double-positive paraneoplastic neurological syndrome in a patient with triple-negative breast cancer
We report a rare case of paraneoplastic neurological syndrome with dual seropositivity of anti-aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies in a 40 year-old woman with metastatic triple-negative breast cancer. She received multiple lines of anti-neoplastic treatment, including immunotherapy with pembrolizumab, as well as cytotoxic chemotherapy. Paraneoplastic meningoencephalomyelitis developed 2 years after diagnosis of breast cancer and 1 year after discontinuation of immunotherapy with pembrolizumab. She first developed longitudinally extending transverse myelitis followed by left optic neuritis and men...
Source: Clinical Breast Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Amna Siddiqui Dylan Ross Ronak H Jani Vikram C Prabhu Shelly Lo Derek A Wainwright Stasia Rouse Tamer Refaat Yirong Zhu Jigisha P Thakkar Source Type: research
Anti-aquaporin-4 immunoglobulin G/anti-myelin oligodendrocyte glycoprotein immunoglobulin G double-positive paraneoplastic neurological syndrome in a patient with triple-negative breast cancer
We report a rare case of paraneoplastic neurological syndrome with dual seropositivity of anti-aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies in a 40 year-old woman with metastatic triple-negative breast cancer. She received multiple lines of anti-neoplastic treatment, including immunotherapy with pembrolizumab, as well as cytotoxic chemotherapy. Paraneoplastic meningoencephalomyelitis developed 2 years after diagnosis of breast cancer and 1 year after discontinuation of immunotherapy with pembrolizumab. She first developed longitudinally extending transverse myelitis followed by left optic neuritis and men...
Source: Clinical Genitourinary Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Amna Siddiqui Dylan Ross Ronak H Jani Vikram C Prabhu Shelly Lo Derek A Wainwright Stasia Rouse Tamer Refaat Yirong Zhu Jigisha P Thakkar Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study
CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: J Chen C Huang M Li Source Type: research
