< em > Jianpi Zishen < /em > granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study

CONCLUSION: The therapeutic effect of JPZS granules on SLE is mediated probably by coordinated actions of quercetin, kaempferol, β-sitosterol, and isorhamnetin on their target gene STAT1 to inhibit the JAK/STAT pathway, thus suppressing autophagy and alleviating podocyte injuries in SLE.PMID:38597437 | PMC:PMC11006693 | DOI:10.12122/j.issn.1673-4254.2024.03.07
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Source Type: research