Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal
CONCLUSIONS: The main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.PMID:38591825 | DOI:10.1590/2175-8239-JBN-2023-0143en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Patr ícia Sousa Catarina Br ás Catarina Menezes Ramon Vizcaino Teresa Costa Maria Sameiro Faria Concei ção Mota Source Type: research

Inhaled bronchodilators for the prevention and treatment of chronic lung disease in preterm infants
CONCLUSIONS: Low-certainty evidence from one trial showed that inhaled bronchodilator prophylaxis may result in little or no difference in the incidence of mortality or CLD in preterm infants, when compared to placebo. The evidence is very uncertain about the effect of salbutamol on pneumothorax, and neither included study reported on the incidence of serious adverse effects. We identified no trials that studied the use of bronchodilator therapy for the treatment of CLD. Additional clinical trials are necessary to assess the role of bronchodilator agents in the prophylaxis or treatment of CLD. Researchers studying the effe...
Source: Cochrane Database of Systematic Reviews - April 9, 2024 Category: General Medicine Authors: Geraldine Ng Matteo Bruschettini John Ibrahim Orlando da Silva Source Type: research

Dupilumab in patients with atopic dermatitis: assessing treatment response, clinical features and potential biomarkers in real-life
Conclusions. In this cohort, none of the evaluated biomarkers at baseline were associated with a better/earlier clinical response to dupilumab. Dupilumab treatment for 52 weeks resulted in a significant and sustained reduction in blood levels of total IgE and allergen-specific IgE to aeroallergens. The potential long-term clinical benefit of these effects, even after discontinuing dupilumab therapy in patients with AD, should be explored to a greater extent.PMID:38591168 | DOI:10.23822/EurAnnACI.1764-1489.341 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: R Lim ão R Br ás E Pedro S L Silva A Lopes Source Type: research

Inhaled bronchodilators for the prevention and treatment of chronic lung disease in preterm infants
CONCLUSIONS: Low-certainty evidence from one trial showed that inhaled bronchodilator prophylaxis may result in little or no difference in the incidence of mortality or CLD in preterm infants, when compared to placebo. The evidence is very uncertain about the effect of salbutamol on pneumothorax, and neither included study reported on the incidence of serious adverse effects. We identified no trials that studied the use of bronchodilator therapy for the treatment of CLD. Additional clinical trials are necessary to assess the role of bronchodilator agents in the prophylaxis or treatment of CLD. Researchers studying the effe...
Source: Cochrane Database of Systematic Reviews - April 9, 2024 Category: General Medicine Authors: Geraldine Ng Matteo Bruschettini John Ibrahim Orlando da Silva Source Type: research

Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal
CONCLUSIONS: The main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.PMID:38591825 | DOI:10.1590/2175-8239-JBN-2023-0143en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Patr ícia Sousa Catarina Br ás Catarina Menezes Ramon Vizcaino Teresa Costa Maria Sameiro Faria Concei ção Mota Source Type: research

Dupilumab in patients with atopic dermatitis: assessing treatment response, clinical features and potential biomarkers in real-life
Conclusions. In this cohort, none of the evaluated biomarkers at baseline were associated with a better/earlier clinical response to dupilumab. Dupilumab treatment for 52 weeks resulted in a significant and sustained reduction in blood levels of total IgE and allergen-specific IgE to aeroallergens. The potential long-term clinical benefit of these effects, even after discontinuing dupilumab therapy in patients with AD, should be explored to a greater extent.PMID:38591168 | DOI:10.23822/EurAnnACI.1764-1489.341 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: R Lim ão R Br ás E Pedro S L Silva A Lopes Source Type: research

Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal
CONCLUSIONS: The main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.PMID:38591825 | DOI:10.1590/2175-8239-JBN-2023-0143en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Patr ícia Sousa Catarina Br ás Catarina Menezes Ramon Vizcaino Teresa Costa Maria Sameiro Faria Concei ção Mota Source Type: research

Dupilumab in patients with atopic dermatitis: assessing treatment response, clinical features and potential biomarkers in real-life
Conclusions. In this cohort, none of the evaluated biomarkers at baseline were associated with a better/earlier clinical response to dupilumab. Dupilumab treatment for 52 weeks resulted in a significant and sustained reduction in blood levels of total IgE and allergen-specific IgE to aeroallergens. The potential long-term clinical benefit of these effects, even after discontinuing dupilumab therapy in patients with AD, should be explored to a greater extent.PMID:38591168 | DOI:10.23822/EurAnnACI.1764-1489.341 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: R Lim ão R Br ás E Pedro S L Silva A Lopes Source Type: research

Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal
CONCLUSIONS: The main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.PMID:38591825 | DOI:10.1590/2175-8239-JBN-2023-0143en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Patr ícia Sousa Catarina Br ás Catarina Menezes Ramon Vizcaino Teresa Costa Maria Sameiro Faria Concei ção Mota Source Type: research

Dupilumab in patients with atopic dermatitis: assessing treatment response, clinical features and potential biomarkers in real-life
Conclusions. In this cohort, none of the evaluated biomarkers at baseline were associated with a better/earlier clinical response to dupilumab. Dupilumab treatment for 52 weeks resulted in a significant and sustained reduction in blood levels of total IgE and allergen-specific IgE to aeroallergens. The potential long-term clinical benefit of these effects, even after discontinuing dupilumab therapy in patients with AD, should be explored to a greater extent.PMID:38591168 | DOI:10.23822/EurAnnACI.1764-1489.341 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: R Lim ão R Br ás E Pedro S L Silva A Lopes Source Type: research

Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal
CONCLUSIONS: The main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.PMID:38591825 | DOI:10.1590/2175-8239-JBN-2023-0143en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Patr ícia Sousa Catarina Br ás Catarina Menezes Ramon Vizcaino Teresa Costa Maria Sameiro Faria Concei ção Mota Source Type: research

Dupilumab in patients with atopic dermatitis: assessing treatment response, clinical features and potential biomarkers in real-life
Conclusions. In this cohort, none of the evaluated biomarkers at baseline were associated with a better/earlier clinical response to dupilumab. Dupilumab treatment for 52 weeks resulted in a significant and sustained reduction in blood levels of total IgE and allergen-specific IgE to aeroallergens. The potential long-term clinical benefit of these effects, even after discontinuing dupilumab therapy in patients with AD, should be explored to a greater extent.PMID:38591168 | DOI:10.23822/EurAnnACI.1764-1489.341 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: R Lim ão R Br ás E Pedro S L Silva A Lopes Source Type: research

Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal
CONCLUSIONS: The main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.PMID:38591825 | DOI:10.1590/2175-8239-JBN-2023-0143en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Patr ícia Sousa Catarina Br ás Catarina Menezes Ramon Vizcaino Teresa Costa Maria Sameiro Faria Concei ção Mota Source Type: research

Dupilumab in patients with atopic dermatitis: assessing treatment response, clinical features and potential biomarkers in real-life
Conclusions. In this cohort, none of the evaluated biomarkers at baseline were associated with a better/earlier clinical response to dupilumab. Dupilumab treatment for 52 weeks resulted in a significant and sustained reduction in blood levels of total IgE and allergen-specific IgE to aeroallergens. The potential long-term clinical benefit of these effects, even after discontinuing dupilumab therapy in patients with AD, should be explored to a greater extent.PMID:38591168 | DOI:10.23822/EurAnnACI.1764-1489.341 (Source: European Annals of Allergy and Clinical Immunology)
Source: European Annals of Allergy and Clinical Immunology - April 9, 2024 Category: Allergy & Immunology Authors: R Lim ão R Br ás E Pedro S L Silva A Lopes Source Type: research