The effect of aerobic and resistance exercise on the progression of colorectal cancer in an animal model
CONCLUSIONS: The study discovered no significant difference in disease activity index scores between groups, but there was a significant difference in the number of polyps and the presence of mucosal ulceration in the colon.PMID:37878986 | PMC:PMC10592869 | DOI:10.1590/acb384923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 25, 2023 Category: Surgery Authors: Marcelo Barbosa Neves Udenilson Nunes da Silva Junior Alessandra de Figueiredo Gon çalves Let ícia Silva Fagundes Ant ônio Carlos de Abreu Luiz Carlos Takita Ricardo Dutra Aydos Rondon Tosta Ramalho Source Type: research

The effect of aerobic and resistance exercise on the progression of colorectal cancer in an animal model
CONCLUSIONS: The study discovered no significant difference in disease activity index scores between groups, but there was a significant difference in the number of polyps and the presence of mucosal ulceration in the colon.PMID:37878986 | PMC:PMC10592869 | DOI:10.1590/acb384923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 25, 2023 Category: Surgery Authors: Marcelo Barbosa Neves Udenilson Nunes da Silva Junior Alessandra de Figueiredo Gon çalves Let ícia Silva Fagundes Ant ônio Carlos de Abreu Luiz Carlos Takita Ricardo Dutra Aydos Rondon Tosta Ramalho Source Type: research

The effect of aerobic and resistance exercise on the progression of colorectal cancer in an animal model
CONCLUSIONS: The study discovered no significant difference in disease activity index scores between groups, but there was a significant difference in the number of polyps and the presence of mucosal ulceration in the colon.PMID:37878986 | PMC:PMC10592869 | DOI:10.1590/acb384923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 25, 2023 Category: Surgery Authors: Marcelo Barbosa Neves Udenilson Nunes da Silva Junior Alessandra de Figueiredo Gon çalves Let ícia Silva Fagundes Ant ônio Carlos de Abreu Luiz Carlos Takita Ricardo Dutra Aydos Rondon Tosta Ramalho Source Type: research

The effect of aerobic and resistance exercise on the progression of colorectal cancer in an animal model
CONCLUSIONS: The study discovered no significant difference in disease activity index scores between groups, but there was a significant difference in the number of polyps and the presence of mucosal ulceration in the colon.PMID:37878986 | PMC:PMC10592869 | DOI:10.1590/acb384923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 25, 2023 Category: Surgery Authors: Marcelo Barbosa Neves Udenilson Nunes da Silva Junior Alessandra de Figueiredo Gon çalves Let ícia Silva Fagundes Ant ônio Carlos de Abreu Luiz Carlos Takita Ricardo Dutra Aydos Rondon Tosta Ramalho Source Type: research

The effect of aerobic and resistance exercise on the progression of colorectal cancer in an animal model
CONCLUSIONS: The study discovered no significant difference in disease activity index scores between groups, but there was a significant difference in the number of polyps and the presence of mucosal ulceration in the colon.PMID:37878986 | PMC:PMC10592869 | DOI:10.1590/acb384923 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - October 25, 2023 Category: Surgery Authors: Marcelo Barbosa Neves Udenilson Nunes da Silva Junior Alessandra de Figueiredo Gon çalves Let ícia Silva Fagundes Ant ônio Carlos de Abreu Luiz Carlos Takita Ricardo Dutra Aydos Rondon Tosta Ramalho Source Type: research

Cancers, Vol. 15, Pages 5126: The Role of Artificial Intelligence in Colorectal Cancer Screening: Lesion Detection and Lesion Characterization
This article presents a comprehensive review of the transformative role of artificial intelligence (AI), which has recently emerged as one such solution for improving the quality of screening and surveillance colonoscopy. Firstly, AI-driven algorithms demonstrate remarkable potential in addressing the challenge of overlooked polyps, particularly polyp subtypes infamous for escaping human detection because of their inconspicuous appearance. Secondly, AI empowers gastroenterologists without exhaustive training in advanced mucosal imaging to characterise polyps with accuracy similar to that of expert interventionalists, reduc...
Source: Cancers - October 24, 2023 Category: Cancer & Oncology Authors: Edward Young Louisa Edwards Rajvinder Singh Tags: Review Source Type: research

Snare tip soft coagulation vs argon plasma coagulation vs no margin treatment after large non-pedunculated colorectal polyp resection: a randomized trial
Thermal treatment of the defect margin after endoscopic mucosal resection (EMR) of large non-pedunculated colorectal lesions reduces the recurrence rate. Both snare tip soft coagulation (STSC) and argon plasma coagulation (APC) have been used for thermal margin treatment, but there are few data directly comparing STSC to APC for this indication. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 21, 2023 Category: Gastroenterology Authors: Douglas K. Rex, Gregory B. Haber, Mouen Khashab, Amit Rastogi, Muhammad K. Hasan, Christopher J. DiMaio, Nikhil A. Kumta, Satish Nagula, Stuart Gordon, Firas Al-Kawas, Jerome D. Waye, Hadie Razjouyan, Charles E. Dye, Matthew T. Moyer, Jeremiah Shultz, Rac Source Type: research

Snare Tip Soft Coagulation vs Argon Plasma Coagulation vs No Margin Treatment After Large Nonpedunculated Colorectal Polyp Resection: a Randomized Trial
Thermal treatment of the defect margin after endoscopic mucosal resection (EMR) of large nonpedunculated colorectal lesions reduces the recurrence rate. Both snare tip soft coagulation (STSC) and argon plasma coagulation (APC) have been used for thermal margin treatment, but there are few data directly comparing STSC with APC for this indication. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 21, 2023 Category: Gastroenterology Authors: Douglas K. Rex, Gregory B. Haber, Mouen Khashab, Amit Rastogi, Muhammad K. Hasan, Christopher J. DiMaio, Nikhil A. Kumta, Satish Nagula, Stuart Gordon, Firas Al-Kawas, Jerome D. Waye, Hadie Razjouyan, Charles E. Dye, Matthew T. Moyer, Jeremiah Shultz, Rac Source Type: research

Usefulness of genotyping APC gene for individualizing management of patients with familial adenomatous polyposis
CONCLUSIONS: Different interventional strategies based on genotypes may be proposed for the clinical management of patients with FAP. This policy needs to be validated in further prospective studies focusing on long-term endoscopic intervention and optimal age at prophylactic (procto)colectomy.PMID:37853284 | DOI:10.1007/s10147-023-02419-6 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - October 18, 2023 Category: Cancer & Oncology Authors: Yoshiko Mori Hideyuki Ishida Noriyasu Chika Tetsuya Ito Kunihiko Amano Kenichi Chikatani Yoji Takeuchi Mitsuhiro Kono Satoki Shichijo Akiko Chino Toshiya Nagasaki Akinari Takao Misato Takao Sakiko Nakamori Kazuhito Sasaki Kiwamu Akagi Tatsuro Yamaguchi Ko Source Type: research

pT1 colorectal cancer: A treatment dilemma
Best Pract Res Clin Gastroenterol. 2023 Oct;66:101854. doi: 10.1016/j.bpg.2023.101854. Epub 2023 Aug 7.ABSTRACTThe implementation of population screening programs for colorectal cancer (CRC) has led to a considerable increase in the prevalence pT1-CRC originating on polyps amenable by local treatments. However, a high proportion of patients are referred for unnecessary oncological surgeries without a clear benefit in terms of survival. Selecting the appropriate endoscopic resection technique in the moment of diagnosis becomes crucial to provide the best treatment alternative to each individual polyp and patient. For this, ...
Source: Clinical Colorectal Cancer - October 18, 2023 Category: Cancer & Oncology Authors: Angelo Brunori Maria Daca-Alvarez Maria Pellis é Source Type: research

Surveillance after colorectal polyp resection
Best Pract Res Clin Gastroenterol. 2023 Oct;66:101848. doi: 10.1016/j.bpg.2023.101848. Epub 2023 Jul 5.ABSTRACTPost-polypectomy surveillance has proven to reduce colorectal cancer (CRC) incidence in patients with high-risk polyps, but it implies a major burden on colonoscopy units. Therefore, it should be targeted to individuals with a higher risk. Different societies have published guidelines on surveillance after resection of polyps, with notable discrepancies among them, and many recommendations come from low-quality evidence based on surrogate measures, such as risk of advanced adenoma, and not CRC risk. In this review...
Source: Clinical Colorectal Cancer - October 18, 2023 Category: Cancer & Oncology Authors: Sandra Baile-Max ía Rodrigo Jover Source Type: research

Usefulness of genotyping APC gene for individualizing management of patients with familial adenomatous polyposis
ConclusionsDifferent interventional strategies based on genotypes may be proposed for the clinical management of patients with FAP. This policy needs to be validated in further prospective studies focusing on long-term endoscopic intervention and optimal age at prophylactic (procto)colectomy. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - October 18, 2023 Category: Cancer & Oncology Source Type: research

Underwater versus conventional endoscopic mucosal resection for colorectal lesions: An updated meta-analysis of randomized controlled trials
Conclusions UEMR is a promising effective technique for removal of colorectal lesions. The most contemporary literature indicates that it improves en bloc resection rate without increasing procedure time, recurrence, or AEs (PROSPERO ID CRD42022374935). [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Endoscopy International Open)
Source: Endoscopy International Open - October 9, 2023 Category: Gastroenterology Authors: Chowdhury, Aneesa Rahman Kim, Jin Sun Xu, Mimi Tom, Chloe Narala, Rachan Kong, Niwen Lee, Helen Vazquez, Alejandro Sahakian, Ara Phan, Jennifer Buxbaum, James Tags: Review Source Type: research

Accuracy of measuring colorectal polyp size in pathology: a prospective study
Message Guideline-conforming endoscopic polyp resection and follow-up are dependent on accurate polyp sizing estimation. However, studies evaluating the feasibility and accuracy of pathology-based polyp size measurement are lacking. We conducted a prospective clinical study (482 polyps resected in 203 consecutive patients) evaluating pathology-based size measurement for colorectal polyps. To obtain reference size measurements, we measured polyp size immediately after removing polyps from the colon prior to formalin fixation. Due to piecemeal resection or fragmentation of specimens during the retrieval process, only 59% of ...
Source: Gut - October 6, 2023 Category: Gastroenterology Authors: Djinbachian, R., Khellaf, A., Noyon, B., Soucy, G., Nguyen, B. N., von Renteln, D. Tags: Gut Endoscopy news Source Type: research

Colon CApsule endoscopy compared to conventional COlonoscopy in patients with colonic DIverticulitis: the study protocol for a randomised controlled superiority trial (CACODI trial)
Introduction Follow-up after an episode of colonic diverticulitis is a common indication for colonoscopy, even though studies have shown a low risk of positive findings in this population. Our objective is to investigate colon capsule endoscopy (CCE) as a follow-up examination in patients with colonic diverticulitis compared with colonoscopy, particularly regarding patient satisfaction and clinical performance. Methods and analysis We will conduct a single-centre prospective randomised controlled trial. Patients seen at Odense University Hospital with acute diverticulitis confirmed by CT will be included and randomised to...
Source: BMJ Open - October 6, 2023 Category: General Medicine Authors: Schelde-Olesen, B., Kaalby, L., Deding, U., Thygesen, M. M. I., Andersen, P. V., Koulaouzidis, A., Baatrup, G., Bjorsum-Meyer, T. Tags: Open access, Surgery Source Type: research