Usefulness of genotyping APC gene for individualizing management of patients with familial adenomatous polyposis

CONCLUSIONS: Different interventional strategies based on genotypes may be proposed for the clinical management of patients with FAP. This policy needs to be validated in further prospective studies focusing on long-term endoscopic intervention and optimal age at prophylactic (procto)colectomy.PMID:37853284 | DOI:10.1007/s10147-023-02419-6

Source: Clinical Colorectal Cancer - October 18, 2023 Category: Cancer & Oncology Authors: Yoshiko Mori Hideyuki Ishida Noriyasu Chika Tetsuya Ito Kunihiko Amano Kenichi Chikatani Yoji Takeuchi Mitsuhiro Kono Satoki Shichijo Akiko Chino Toshiya Nagasaki Akinari Takao Misato Takao Sakiko Nakamori Kazuhito Sasaki Kiwamu Akagi Tatsuro Yamaguchi Ko Source Type: research