Roche provides update on phase III studies of etrolizumab in people with moderately to severely active ulcerative colitis
Basel, 10 August 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced topline results from its phase III study programme evaluating the investigational medicine etrolizumab in people with moderately to severely active ulcerative colitis. Mixed results were seen in studies evaluating etrolizumab as an induction therapy, and both studies evaluating etrolizumab as a maintenance therapy failed to meet their primary endpoints, showing no significant difference in the proportion of people achieving remission with subcutaneous etrolizumab versus placebo. In the HIBISCUS I induction study, in people without prior anti-tumour ...
Source: Roche Media News - August 10, 2020 Category: Pharmaceuticals Source Type: news

Roche provides update on phase III studies of etrolizumab in people with moderately to severely active ulcerative colitis
Basel, 10 August 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced topline results from its phase III study programme evaluating the investigational medicine etrolizumab in people with moderately to severely active ulcerative colitis. Mixed results were seen in studies evaluating etrolizumab as an induction therapy, and both studies evaluating etrolizumab as a maintenance therapy failed to meet their primary endpoints, showing no significant difference in the proportion of people achieving remission with subcutaneous etrolizumab versus placebo. In the HIBISCUS I induction study, in people without prior anti-tumour ...
Source: Roche Investor Update - August 10, 2020 Category: Pharmaceuticals Source Type: news

Early Colectomy for Toxic Megacolon in C. difficile Infection Early Colectomy for Toxic Megacolon in C. difficile Infection
Can early colectomy in patients who have toxic megacolon due to Clostridium difficile colitis improve outcomes and reduce mortality?Southern Medical Journal (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 4, 2020 Category: Surgery Tags: General Surgery Journal Article Source Type: news

What Is Laparoscopic Left Colectomy/Hemicolectomy?
Title: What Is Laparoscopic Left Colectomy/Hemicolectomy?Category: Procedures and TestsCreated: 7/10/2020 12:00:00 AMLast Editorial Review: 7/10/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 10, 2020 Category: Nutrition Source Type: news

What Is Laparoscopic Right Colectomy?
Title: What Is Laparoscopic Right Colectomy?Category: Procedures and TestsCreated: 7/9/2020 12:00:00 AMLast Editorial Review: 7/9/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 9, 2020 Category: Nutrition Source Type: news

Potential for Prognostic Biomarkers in T1 Colorectal Cancer Treatment Selection
In this study, researchers found that endoscopic therapy was the most effective strategy for patients with T1 CRC with less aggressive biomarker profiles and laparoscopic colectomy was the most effective for patients with more aggressive profiles. (Source: CancerNetwork)
Source: CancerNetwork - March 23, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Biologics May Have Changed the Natural History of Ulcerative Colitis Biologics May Have Changed the Natural History of Ulcerative Colitis
The rate of colectomy within the first year after hospital admission for ulcerative colitis has declined in the modern era of biologics, suggesting the advent of biologic therapy has changed the natural history of the disease, researchers report.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 30, 2020 Category: Surgery Tags: Gastroenterology News Source Type: news

Robotic Colectomy Safe but Expensive Robotic Colectomy Safe but Expensive
Robotic colectomy appears to be only minimally safer than open colectomy (but not laparoscopic colectomy) and is more costly than the other two alternatives, but its use continues to increase, according to new research.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - November 7, 2019 Category: Surgery Tags: General Surgery News Source Type: news

Bowel Preparation Does Not Reduce Morbidity of Elective Colectomy Bowel Preparation Does Not Reduce Morbidity of Elective Colectomy
Mechanical and oral antibiotic bowel preparation (MOABP) does not reduce surgical site infections (SSIs) or overall morbidity after elective colectomy, compared with no bowel preparation, according to results from the MOBILE trial.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 20, 2019 Category: Surgery Tags: General Surgery News Source Type: news

Mechanical, Oral Antibiotic Bowel Prep Yields No Benefit for Colectomy
MONDAY, Aug. 19, 2019 -- Mechanical and oral antibiotic bowel preparation (MOABP) does not reduce surgical site infections (SSIs) or the overall morbidity of colon surgery versus no bowel preparation (NBP), according to a study published online Aug.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 19, 2019 Category: Pharmaceuticals Source Type: news

Diverting Loop Ileostomy Increasingly Used to Manage Fulminant C Difficile Colitis Diverting Loop Ileostomy Increasingly Used to Manage Fulminant C Difficile Colitis
Diverting loop ileostomy (LI) is increasingly favored over total abdominal colectomy (TAC) for the surgical management of patients with fulminant Clostridium difficile colitis, according to a new study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - July 13, 2019 Category: Surgery Tags: Gastroenterology News Source Type: news

Infliximab Introduction Has Not Cut IBD-Related Hospitalizations
FRIDAY, June 14, 2019 -- Marketplace introduction of infliximab has not resulted in reductions in the population rates of inflammatory bowel disease (IBD)-related hospitalizations or intestinal resections or colectomies, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 14, 2019 Category: Pharmaceuticals Source Type: news

Complications After Colectomy: Does Procedure Type Matter? Complications After Colectomy: Does Procedure Type Matter?
Dr Lowenfels comments on a study comparing hernia and bowel obstruction rates of laparoscopic versus open surgery for rectal cancer.Medscape General Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 3, 2019 Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news

Single vs Multiport Lap Colectomy: Only Benefit Cosmetic? Single vs Multiport Lap Colectomy: Only Benefit Cosmetic?
Dr Lowenfels comments on a study that compares the outcomes of single-incision and multiport laparoscopy for colonic surgery.Medscape General Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 19, 2019 Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news

Fewer Colectomy Procedures Performed Among Ulcerative Colitis Patients
(MedPage Today) -- Surveillance efforts may lead to more treatment options for this patient group (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - February 8, 2019 Category: Surgery Source Type: news

Post-Inflammatory Polyps Not Linked to Colorectal Neoplasia
FRIDAY, Dec. 14, 2018 -- For patients with inflammatory bowel disease (IBD), post-inflammatory polyps (PIPs) are associated with greater severity and extent of colon inflammation and higher rates of colectomy, but not with development of colorectal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 14, 2018 Category: Pharmaceuticals Source Type: news

Surgeon Experience and Medicare Expenditures for Colectomy Surgeon Experience and Medicare Expenditures for Colectomy
How do Medicare payments for laparoscopic and open colectomy compare? Might a surgeon's experience impact payment?Annals of Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 10, 2018 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

Colectomy Appears to Increase Later Risk of Type 2 Diabetes
WEDNESDAY, Nov. 7, 2018 -- Patients who have the entire or left side of the colon removed show increased risk for developing type 2 diabetes in the 18 years following surgery, according to a study published online Oct. 30 in eLife. Anders B. Jensen,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 7, 2018 Category: Pharmaceuticals Source Type: news

Colectomy May Boost Diabetes Risk (CME/CE)
(MedPage Today) -- Large registry study suggests role for altered intestinal microbiota and hormones post-surgery (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - November 2, 2018 Category: Urology & Nephrology Source Type: news

Colectomy patients may have a higher risk of diabetes
Research, published ineLife,suggests that patients who have had a complete colectomy, or the left side of their colon removed, have an increased risk of developing type-2 diabetes.MedicalXpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 2, 2018 Category: Endocrinology Source Type: news

ACS: Opiate-Free Surgery Feasible for Elective Colectomy
TUESDAY, Oct. 23, 2018 -- Opiate-free surgery is feasible for patients undergoing elective colon resections with anastomosis, with shorter length of stay for patients not receiving narcotics, according to a study presented at the annual meeting of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 23, 2018 Category: Pharmaceuticals Source Type: news

IV Acetaminophen Minimally Helpful for Colectomy Pain
FRIDAY, July 6, 2018 -- Intravenous acetaminophen does not decrease opioid utilization to a clinically significant threshold among colectomy patients, according to a study published in the July issue of Anesthesiology. Isaac Wasserman, M.P.H., from... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 6, 2018 Category: Pharmaceuticals Source Type: news

No Surgical Gains from Accelerated Infliximab in Acute UC
(MedPage Today) -- Colectomy rates similar to those with standard induction therapy (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 29, 2018 Category: Gastroenterology Source Type: news

Ambulatory Colectomy Safe, Feasible for'Carefully Selected' Patients Ambulatory Colectomy Safe, Feasible for'Carefully Selected' Patients
Many patients who require elective colectomy may be candidates for ambulatory surgery, new research shows.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - May 29, 2018 Category: Surgery Tags: General Surgery News Source Type: news

You Will Have a New Life You Will Have a New Life
A deeply personal account of a physician's difficult journey after a total colectomy, and how she was able to build the"new life" she was promised--but not quite in the way she expected.Annals of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 21, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

C. Difficile Risk Higher With Stoma Reversal Versus Colectomy
WEDNESDAY, April 18, 2018 -- Patients who undergo elective stoma reversal have a higher incidence of postoperative Clostridium difficile infection versus patients who undergo elective colectomy, according to a study published in the May issue of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 18, 2018 Category: Pharmaceuticals Source Type: news

SafeHeal raises $7m
Early stage medtech dev SafeHeal said today it has raised $7.4 million (EU €6 million) in a Series A round of financing, with funds slated to support the clinical and regulatory market access and a commercial launch. The Paris-based company is developing the Colovac, a digestive anastomosis protection device designed to reduce complications and remove the need for ostomies in colectomy patients. The system consists of a minimally invasive, full reversible implant that remains in place for approximately two weeks, or until tissue repair is complete, before removal. “This investment enables us to execute our aggre...
Source: Mass Device - March 23, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News safeheal Source Type: news

Gender Gap in Surgery Needs to End: General Surgery News
(MedPage Today) -- Also, location matters when it comes to incisional hernia risk after colectomy (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 7, 2018 Category: Gastroenterology Source Type: news

Enhanced-recovery Protocol Linked to Better Colectomy Outcomes Enhanced-recovery Protocol Linked to Better Colectomy Outcomes
Implementing enhanced-recovery protocols (ERPs) is associated with reduced length of stay (LOS) and complication risk after colectomy, a new pilot study in 15 U.S. hospitals confirms.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 2, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Why a Two-Pound Robot is Getting Love from Investors
About two-thirds of colon resection procedures are performed via open surgery with an eight- to 12-inch incision and several weeks of recovery time. A miniature robotically assisted surgical device (RASD) developed by a company called Virtual Incision could change that.  Virtual Incision is just about ready to go to FDA seeking a 510(k) clearance for its two-pound RASD that operates entirely inside the body through a single abdominal incision and is expected to be less expensive and more portable than existing laparoscopic surgery robots. To help it get there, investors recently poured $18 million into ...
Source: MDDI - December 13, 2017 Category: Medical Devices Authors: Amanda Pedersen Tags: Medical Device Business R & Source Type: news

New Analytic Approach Pinpoints Laparoscopic Colectomy Savings New Analytic Approach Pinpoints Laparoscopic Colectomy Savings
Laparoscopic colectomy is more cost-effective than open surgery, with most of the savings derived from reduced use of health services after discharge and fewer readmissions, according to researchers who used a novel analytic approach known as instrumental variable analysis.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - June 23, 2017 Category: Surgery Tags: General Surgery News Source Type: news

Both Older and Younger Patients Benefit from Laparoscopic Colectomy
(MedPage Today) -- Younger patients less likely to be discharged to facility (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 23, 2017 Category: Gastroenterology Source Type: news

COPD Patients Needing Colectomy Do Better with Laparascopic Surgery
(MedPage Today) -- Shorter stays, lower readmission rates vs open procedures (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 23, 2017 Category: Gastroenterology Source Type: news

Does Mesh for Hernias Hold Up? General Surgery News Report
(MedPage Today) -- Also, cost cutting with laparoscopic colectomy, new journal app (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - February 22, 2017 Category: American Health Source Type: news

Recurrence of Crohn's Disease After TC-PI Recurrence of Crohn's Disease After TC-PI
Is total colectomy with permanent ileostomy for medically refractory colonic Crohn's disease curative?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 21, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Colectomy for Ulcerative Colitis Tied to Gallstone Disease Colectomy for Ulcerative Colitis Tied to Gallstone Disease
The risk of gallstone disease is increased following colectomy for ulcerative colitis, researchers have found.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - February 11, 2017 Category: Surgery Tags: Hematology-Oncology News Source Type: news

MassDevice.com +5 | The top 5 medtech stories for September 13, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Orthofix launches study of pulsed electromagnetic fields in treating osteoarthritis Orthofix said today it enrolled the 1st patient in a study exploring the use of its Physio-Stim pulsed electromagnetic field system for treatin...
Source: Mass Device - September 13, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Ethicon wins FDA nod for Enseal X1 tissue sealer
Johnson & Johnson (NYSE:JNJ) subsidiary Ethicon  said today it won FDA 510(k) clearance for its Enseal X1 large jaw tissue sealer designed for vessel sealing and precise heat management. The Somerville, N.J.-based company said the newly cleared Enseal X1 is an advanced bipolar device designed for use in open procedures, such as colectomies and hysterectomies. “Ethicon remains committed to addressing the critical needs of patients, ensuring they have access to the most effective treatment through continued innovation and product enhancement. By providing access to leading-edge technology in adv...
Source: Mass Device - September 12, 2016 Category: Medical Equipment Authors: Fink Densford Tags: 510(k) Food & Drug Administration (FDA) Regulatory/Compliance Surgical Ethicon Source Type: news

Dartmouth researchers develop a new method to transparently measure health care value
(The Dartmouth Institute for Health Policy & Clinical Practice) Dartmouth researchers used Hospital Compare and Medicare expenditure data for 2012 to construct a hospital-level measure of value. They used a numerator composed of quality care measures (satisfaction, use of timely and effective care, and avoidance of harms) and a denominator composed of risk-adjusted 30 day episode-of-care expenditures for four admission types: acute myocardial infarction, coronary artery bypass grafting, colectomy, and hip replacement surgery. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 6, 2016 Category: Global & Universal Source Type: news

Colectomy dominates TNF-α inhibitors for ulcerative colitis
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - May 1, 2016 Category: Drugs & Pharmacology Source Type: news

Appendectomy and Colectomy Risk in Ulcerative ColitisAppendectomy and Colectomy Risk in Ulcerative Colitis
Appendectomy does not decrease, and may increase, the risk of colectomy in patients with ulcerative colitis (UC), according to a retrospective study and meta-analysis. Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - April 30, 2016 Category: Surgery Tags: Gastroenterology News Source Type: news

What is the Recurrence Risk for Clostridium difficile Infection?
Discussion Clostridium difficile infection (CDI) is a common cause of nosocomial diarrhea. Clostridium difficile is an obligate, anaerobic, gram-positive bacillus that is spore-forming and toxin producing. It is resistant to acid, heat, antibiotics and many antiseptic agents. Spores are acquired from the environment or by oral-fecal route. Once in the colon, the bacteria attach and proliferate making vegetative forms. Two main toxins are produced which disrupt the colonic integrity. Toxin A (TcdA) is an endotoxin that disrupts the mucosal cells. Toxin B (TcdB) is a cytotoxin that is 1000x more potent than TcdA and causes a...
Source: PediatricEducation.org - March 28, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Teamwork Makes a Life-Changing Difference for Luis
Each year, about 500,000 Americans have to have their colons removed. Whether it’s because of cancer, trauma, diverticulitis or an inflammatory disease, colectomy may be necessary to save their lives. That was the case for Luis, a special young man who came a long way for help. His surgical team at Mayo Clinic found a [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 22, 2016 Category: Databases & Libraries Source Type: news

How to Eat After Colectomy Surgery
If you've had colectomy surgery, these tips will help you eat well and keep symptoms and side effects from the surgery to a minimum. (Source: About.com Colon Cancer)
Source: About.com Colon Cancer - February 14, 2016 Category: Cancer & Oncology Authors: coloncancer.guide at about.com Tags: health Source Type: news

Even surgery may not help patients with severe constipation
(Wiley) Current guidelines for treating severe constipation include surgical removal of part of the colon, a procedure called subtotal colectomy. Using national databases of hospital activity in the United States, investigators have discovered that colectomies for constipation nearly tripled over a span of 13 years, from 104 procedures in 1998 to 311 in 2011. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 5, 2015 Category: Global & Universal Source Type: news

Colectomy with EI cost effective for Crohn's disease colitis
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - October 1, 2015 Category: Drugs & Pharmacology Source Type: news

Lower Mortality with Elective Surgery vs. Medical Therapy in Advanced Ulcerative Colitis (FREE)
By Douglas K. Rex, MD Dr. Rex is an associate editor with NEJM Journal Watch Gastroenterology, from which this summary was adapted. See full coverage at the link below.Elective colectomy is associated with lower mortality than medical therapy in patients aged 50 years and older with … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 14, 2015 Category: Primary Care Source Type: news

Study shows short & long-term cost-savings associated with minimally invasive surgery
(University Hospitals Case Medical Center) JAMA study demonstrates that patients who underwent laparoscopic colectomy procedures required fewer days of health care utilization and the health care system spent less on their acute and follow-up care than those who underwent traditional open surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 30, 2015 Category: Global & Universal Source Type: news

Ulcerative Colitis: Markers Predict Outcomes With InfliximabUlcerative Colitis: Markers Predict Outcomes With Infliximab
A five-marker panel identifies those at highest risk for relapse and colectomy. Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 24, 2015 Category: Gastroenterology Tags: Gastroenterology News Source Type: news