Accuracy of measuring colorectal polyp size in pathology: a prospective study

Message Guideline-conforming endoscopic polyp resection and follow-up are dependent on accurate polyp sizing estimation. However, studies evaluating the feasibility and accuracy of pathology-based polyp size measurement are lacking. We conducted a prospective clinical study (482 polyps resected in 203 consecutive patients) evaluating pathology-based size measurement for colorectal polyps. To obtain reference size measurements, we measured polyp size immediately after removing polyps from the colon prior to formalin fixation. Due to piecemeal resection or fragmentation of specimens during the retrieval process, only 59% of resected polyps could actually be evaluated histologically for size. The estimated mean polyp shrinkage because of formalin fixation was 26% which resulted in 33% of polyps ≥10 mm pre-fixation being miscategorised as <10 mm post-fixation, and 33% of polyps ≥5 mm pre-fixation being miscategorised as <5 mm post-fixation. Compared with reference size, relative accuracy for measuring polyp size during colonoscopies using a laser-based virtual scale endoscope (VSE) was significantly...
Source: Gut - Category: Gastroenterology Authors: Tags: Gut Endoscopy news Source Type: research