Extreme shock and cardiac arrest in COVID patient
This is a 30-something healthy patient presented with COVID pneumonia who presented to the ED. He was moderately hypoxic. He had the following EKG recorded:Low voltage, suggests effusion.(see Ken ' s discussion of low voltage below)There is a QS-wave in V2.There is minimal, probably normal STE in V2-V6.A bedside cardiac ultrasound was normal, with no effusion. He had troponins ordered, and the first returned at 72 ng/L (Abbott Architect hs cTnI; URL for males = 34 ng/L). An elevated troponin in a COVID patient confers about 4x the risk of mortality than a normal one.He was admitted on oxygen and was&...
Source: Dr. Smith's ECG Blog - November 12, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs
This skill can be taught and learned
I was texted this ECG by a former resident, who just just graduated (there are 2 images of thesame ECG, as they are not of high quality):What do you think?It came with the message: " Thanks for the good training, Steve! "I responded: " Sweet! This would have been missed by almost anyone. " It is diagnostic ofLADOMI (but not STEMI!). OMI= Occlusion Myocardial Infarction.This physician said he had been handed the ECG just before starting a shift, while being told it is a woman with chest pain, and he immediately activated the cath lab based on just that information + the ECG.As all emergency physi...
Source: Dr. Smith's ECG Blog - November 8, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs
Fight Aging! Newsletter, November 2nd 2020
In conclusion, the circulating antibody repertoire has increased binding to thousands of peptides in older donors, which can be represented as an immune age. Increased immune age is associated with autoimmune disease, acute inflammatory disease severity, and may be a broadly relevant biomarker of immune function in health, disease, and therapeutic intervention. The immune age has the potential for wide-spread use in clinical and consumer settings.
In Vivo Reprogramming Improves Cognitive Function in Old Mice
https://www.fightaging.org/archives/2020/10/in-vivo-reprogramming-improves-cognitive-function-in-old-mi...
Source: Fight Aging! - November 1, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Nasal Endoscopy for Urgent and Complex ED Cases
Fiberoptics and endoscopy have changed the way we treat patients in the emergency department. Endoscopes are relatively easy to use, and can aid your diagnosis and treatment plan. Endoscopy may be useful in urgent cases, such as epistaxis, nasal foreign bodies, and ear debridement. It may also be helpful when dealing with more complicated presentations and critically ill patients, such as those with Ludwig's angina, epiglottis, tracheostomies, or those who need intubation.Fiberoptic tools are not just for surgeons and consultants. The endoscope has many uses in the emergency department, and we have a few tips and tricks...
Source: The Procedural Pause - October 28, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Research into the Mechanisms of Aging is Very Poorly Funded in Comparison to its Importance to Health
Research into aging is sparsely funded in comparison to research into the biochemistry and treatment of any specific common age-related disease, such as atherosclerosis or Alzheimer's disease. Yet these conditions are caused by aging. So we have the strange situation in which the past century of work on treating age-related conditions has produced only small gains, because the research and development communities have steadfastly refused to work on the root cause of these conditions - which is to say the mechanisms of aging, the accumulation of cell and tissue damage that causes degeneration and dysfunction.
This pr...
Source: Fight Aging! - October 26, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, October 19th 2020
In conclusion, we found that regardless of the presence of multimorbidity, engaging in a healthier lifestyle was associated with up to 6.3 years longer life for men and 7.6 years for women; however, not all lifestyle risk factors equally correlated with life expectancy, with smoking being significantly worse than others.
A Hydrogel Scaffold to Encourage Peripheral Nerve Regeneration
https://www.fightaging.org/archives/2020/10/a-hydrogel-scaffold-to-encourage-peripheral-nerve-regeneration/
The nervous system of mammals is poorly regenerative at best. The use of implantable scaffold materials is one of th...
Source: Fight Aging! - October 18, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
COVID-19 as a Disease of Aging
Researchers are writing a great many papers these days to point out the obvious regarding COVID-19, that the vast majority of SARS-CoV-2 coronavirus mortality occurs in olders individuals, particularly those who already suffer age-related disease and thus a high burden of tissue and immune system dysfunction. This process of repeating the obvious seems necessary, given that the public discourse on the topic of the present pandemic presents it as a condition that affects all members of society more or less equally. In fact it is a condition that does little more than inconvenience near all younger people who are infected, w...
Source: Fight Aging! - October 15, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Penicillin: the accident that saved many lives
Alexander Fleming in his laboratory, 1881 – 1955
There have been many happy accidents in science. Several of these were of great benefit to medicine.
For example, in 1895, a German physicist working with a cathode ray tube happened to place his hand in front of the rays and found that he could see his bones in the image projected onto the screen. Soon after that, the first X-ray images were produced.
There have been other instances where serendipity played a role in unearthing effective treatments against diseases.
THE FIND OF THE 20TH CENTURY
The most famous of these happy accidents is the discovery ...
Source: GIDEON blog - September 28, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Microbiology News Source Type: blogs
Post #52 Overkill: When Modern Medicine Goes Too Far by Paul Offit M.D.
Overkill: When Modern Medicine Goes Too Far by Paul Offit M.D.I am admittedly a huge fanboy of Paul Offit, an infectious disease guru at Children ' s Hospital of Philadelphia, one of the preeminent pediatric hospitals in the world. His latest bookOverall: When Modern Medicine Goes Too Far, is a collection of medical facts that are already known to the well-read individual, but fly in the face of wrongly-held, out-dated, commonly-believed medical concepts. The majority of the incorrect information was previously considered the standard of care, but newer and better science and studies have clearly demonstrate...
Source: A Pediatrician's Blog - September 23, 2020 Category: Pediatrics Source Type: blogs
EchoNous KOSMOS 3-in-1 Ultrasound, Electronic Stethoscope, and ECG Helps with COVID-19
EchoNous, a developer of novel ultrasounds, has found a way to leverage multiple critical clinical technologies within a single device. The result is KOSMOS, a handheld 3-in-1 device consisting of an ultrasound, electronic stethoscope, and an ECG, all linked via artificial technology.
When COVID-19 was hitting NYC earlier this year, EchoNous was able to use KOSMOS to help diagnose COVID patients and to inform on treatment strategies. We had a lovely chat with Dr. Richard Hoppmann, a key member of EchoNous, Clinical Professor of Internal Medicine at the University of South Carolina, and the Director of the Ultrasound I...
Source: Medgadget - September 21, 2020 Category: Medical Devices Authors: Alice Ferng Tags: Cardiology Critical Care Diagnostics Exclusive Informatics Medicine Public Health Source Type: blogs
Dignity and Respect Might Be More Important Than Safety to Older Adults
What if living means risking injury? That is the question many adult children ask. Older bones don’t mend quickly and sometimes a break can be life-threatening. Pneumonia or flu can also be life-threatening. Some adult children would like to wrap their elders in bubble wrap and keep them safely in their favorite chair. But staying safe, yet not doing the things that one loves - at least those things one is still capable of doing - is no way to live the last years of life.
Continue reading on HealthCentral to learn more about how to help your older adults by recognizing that a certain amount of risk can contribute t...
Source: Minding Our Elders - September 15, 2020 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Suspension Therapy for Pressure Injuries: A Rediscovered Footnote to Nazi Medicine
Shortly after the end of WWII, a British medical officer inspecting a military hospital in Germany observed a treatment for pressure injuries developed by Nazi doctors. The officer’s name was Captain James Fulton Neil and his case report was published in the British Medical Journal along with a photograph of the unfortunate patient reproduced above. The treatment employed suspension by wires drilled into pelvic bones, and I discovered Captain Neil’s article while researching the history of wound care. This post is a summary of my paper recently published in Advances in Skin & Wound Care that describes the a...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - September 14, 2020 Category: Geriatrics Authors: Jeffrey M Levine Tags: Featured Medical Articles Geriatric Medicine Pressure Injuries & Wound Care bedsore bedsores decubiti decubitus ulcer Jeff Levine MD Jeffrey M Levine MD medical history pressure sore pressure sores pressure ulcer pressure ulcers Source Type: blogs
Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit.
Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Adenosine Signaling via the A1 Receptor Reverses Age-Related Decline in Neutrophil Function
The objective of this study was to explore the age-driven changes in the EAD pathway and its impact on PMN function.
PMNs from old mice failed to efficiently kill pneumococci ex vivo; however, supplementation with adenosine rescued this defect. To identify which adenosine receptors is involved, we used specific agonists and inhibitors. We found that A1 receptor signaling was crucial for PMN function as inhibition or genetic ablation of A1 impaired the ability of PMNs from young mice to kill pneumococci. Importantly, activation of A1 receptors rescued the age-associated defect in PMN function. In exploring mechanisms...
Source: Fight Aging! - August 21, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
