FDA-Approved At-Home Spirometer: Interview with Charvi Shetty, Co-Founder and CEO at Aluna
The COVID-19 pandemic has put lung health firmly in our minds. For those with chronic lung diseases, such as asthma and COPD, an important way to keep track of lung health is to use a spirometer to measure how well air can move in and out of the lungs during forced breathing. However, patients would typically attend with a lung specialist to perform this test. This is inconvenient and precludes regular monitoring to keep a close eye on lung health and spot any upcoming disease exacerbation. This is the motivation behind this latest technology, an at-home digital spirometer, created by a medical startup called Aluna. The...
Source: Medgadget - October 17, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery Cardiology Diagnostics Exclusive Medicine Pediatrics Rehab Thoracic Surgery Source Type: blogs

The college football fans that beat COVID and the experts that couldn ’t
BY ANISH KOKA The COVID pandemic was supposed to herald the end of the idea that a smaller government is a better government. The experts who desperately seek to be in charge of a sprawling bureaucratic state told us that it was only a powerful central authority that could do what was needed to safeguard individual liberties at a time when a highly contagious respiratory virus was spreading across the globe. New Zealand may have imposed draconian policies that did not even allow its own citizens to return, but scenes of cheering unmasked New Zealanders stood in sharp contrast to empty seats in American stadiums when ...
Source: The Health Care Blog - October 12, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: COVID-19 Health Policy College Football New Zealand Source Type: blogs

Algae-Based Microrobots Deliver Antibiotics within Lungs
Researchers at the University of California San Diego have developed a microrobot system to treat bacterial pneumonia. The microrobots consist of living algal cells that can swim very effectively in biological fluids, allowing them to navigate throughout the lungs and deliver drugs to difficult-to-reach areas. The algal cells are studded with antibiotic-loaded polymer spheres that are coated with cell membranes from neutrophils, which help them to neutralize inflammatory molecules that are released by bacteria in the lungs, providing a localized anti-inflammatory effect. In tests in mice with bacterial pneumonia, the micro...
Source: Medgadget - September 28, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Critical Care Materials Medicine Nanomedicine UCSD Source Type: blogs

Fight Aging! Newsletter, September 19th 2022
Conclusion Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life. Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Influenza Vaccination Correlates with Modestly Lower Risk of Stroke
Following on from a recent study that suggested undergoing yearly vaccination for influenza can greatly reduce Alzheimer's risk, researchers here show that influenza vaccination correlates with a lower risk of stroke. The mechanisms of interest behind both of these correlations seem likely to revolve around chronic inflammation, an important factor in both the growth of atherosclerotic plaques in blood vessels and the onset and progression of neurodegenerative conditions. Firstly, suffering influenza is an inflammatory event, and the vaccine lowers the incidence and severity of that outcome. Secondly vaccination of this so...
Source: Fight Aging! - September 16, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Aging Diminishes Mucociliary Clearance of the Lung
Countless processes operating in the body progressively fail with age, each one an inconvenience at the outset, and many turning from that to an ultimately fatal reduction in vital capabilities over the decades of later life. The defense against pathogens offered by innate immune functions, including generation of mucus to trap and expel pathogens, holds up relatively well with advancing age, in comparison to many organs, but it is nonetheless is reduced in capacity with age. Researchers note here that the mucosal systems of the lung suffer detrimental changes with aging, with the consequence of increased vulnerability to ...
Source: Fight Aging! - September 15, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How Will A.I. Penetrate Healthcare? Through Your Skin, Voice And Cough!
There is certainly no shortage of research on artificial intelligence, machine and deep learning algorithms these days. You will come across a number of announcements every week reporting on fascinating findings, new methods, and breakthrough results. Despite the unquestionable buzz, it is challenging to pinpoint examples that actually found their way into everyday medical practice, that became part of “standard” healthcare.  In this article, we will introduce three areas we believe will be the forerunners of the A.I. revolution in medicine and will discuss four principles that help to determine whether you ...
Source: The Medical Futurist - August 30, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Artificial Intelligence in Medicine Digital Health Research Future of Medicine AI doctors vocal biomarkers Future of healthcare medical algorithm skin checking app cough analysis Source Type: blogs

3 Powerful Real-World A.I. Examples That Are Used by Patients in Healthcare
There is certainly no shortage of research on artificial intelligence, machine and deep learning algorithms these days. You will come across a number of announcements every week reporting on fascinating findings, new methods, and breakthrough results. Despite the unquestionable buzz, it is challenging to pinpoint examples that actually found their way into everyday medical practice, that became part of “standard” healthcare.  In this article, we will introduce three areas we believe will be the forerunners of the A.I. revolution in medicine and will discuss four principles that help to determine whether you ...
Source: The Medical Futurist - August 30, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Artificial Intelligence in Medicine Digital Health Research Future of Medicine AI doctors vocal biomarkers Future of healthcare medical algorithm skin checking app cough analysis Source Type: blogs

60 year old with vomiting, diarrhea, and syncope: is this Wellens? Is this type 2 MI?
 Written by Jesse McLaren, with edits/comments by Smith and Grauer A 60 year-old patient with diabetes and ESRD presented with 24 hours of vomiting, diarrhea, weakness and then a syncopal episode. Vitals: RR 18, sat 98%, HR 103, BP 124/71 and temp 38.0. Here ’s their ECG: is this Wellens?  There ’s borderline sinus tach, normal conduction, normal axis, and low voltages in the limb leads. The anterior leads have loss of R waves, mild convex ST segments and primary T wave inversion. In the context of QS waves, T wave inversion indicates old or subacute infarct, or reperfusion after signif icant infarc...
Source: Dr. Smith's ECG Blog - August 19, 2022 Category: Cardiology Authors: Jesse McLaren Source Type: blogs

Fight Aging! Newsletter, August 8th 2022
In conclusion, aging research will benefit from a better definition of how specific regulators map onto age-dependent change, considered on a phenotype-by-phenotype basis. Resolving some of these key questions will shed more light on how tractable (or intractable) the biology of aging is. Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes? https://www.fightaging.org/archives/2022/08/does-acarbose-extend-life-in-short-lived-species-via-gut-microbiome-changes/ Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a...
Source: Fight Aging! - August 7, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Aging and the Severity of Inflammatory Infectious Disease Such as SARS-CoV-2
This article provides a pathophysiologic view of COVID-19 in older adults within the frame of inflammaging, with a focus on antiinflammatory treatments for acute and postacute disease. How can Biology of Aging Explain the Severity of COVID-19 in Older Adults Aging has been identified as one of the most relevant risk factors for poor outcomes in COVID-19 disease, independently from the presence of preexisting diseases. The COVID-19 mortality risk sharply increases for elderly subjects, as showed by the reports of China, Italy, and the United States. In particular, in Italy, case fatality rate for patient a...
Source: Fight Aging! - August 2, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

A man in his 50s with hypoxemic respiratory failure from COVID pneumonia develops chest pain
Submitted by anonymous, written by Parker Hambright, MD, peer reviewed by Meyers, Smith, McLarenA man in his 50s with a past medical history of hypertension and tobacco use disorder, who tested COVID positive 11 days prior, presented to the emergency department with worsening shortness of breath over several days. He was tachypneic and hypoxemic down to as low as 44% with reportedly good SpO2 waveform before EMS applied noninvasive ventilation with improvement to 85-89%. Although history was limited by extremis, the report is that there was no chest pain at initial presentation, only shortness of breath.Here is his ECG on ...
Source: Dr. Smith's ECG Blog - July 25, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

Does a Single Troponin below the 99th percentile URL Rule out Acute MI if the Chest pain is very prolonged?
A 66 y.o. male who presented for chest pain that started this AM when he woke up, and has  persisted throughout the day prompting him to call 911. He says the pain is dull in nature and located across the chest, does not radiate, that it isworse with exhalation. He denies worsening with activity or positioning.  He endorses SOB and requested to sit up. He says this has not happened to him before. He endorses cough productive of yellow sputum.  He denies any edema. Denies history of venous thromboembolism.  He endorses a 50 pack year history of smoking. He denies recent illness or recent s...
Source: Dr. Smith's ECG Blog - May 26, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs

It ’s time to focus on non-ventilator hospital-acquired pneumonia
Pneumonia is the deadliest of all hospital-acquired infections in the United States, costs 3 billion dollars per year and is the leading cause of new antibiotic initiation in hospitals. Hospital-acquired pneumonia is classified as either ventilator-associated pneumonia (VAP) or non-ventilator hospital-acquired pneumonia (NVHAP). For the past 15 years, VAP has dominated our attention, resulting inRead more …It’s time to focus on non-ventilator hospital-acquired pneumonia originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 14, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/dian-baker-ellen-benjamin-karen-k-giuliano" rel="tag" data-wpel-link="internal" > Dian Baker, PhD, APRN-BC, Ellen Benjamin, RN, and Karen K. Giuliano, PhD, RN, MBA < /a > < /span > Tags: Conditions Critical Care Pulmonology Source Type: blogs

Weekly Overseas Health IT Links – 26th March, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.-----https://mhealthintelligence.com/news/55-of-telehealth-providers-frustrated-with-overblown-patient-expectations55% of Telehealth Providers Frustrated With Overblown Patient ExpectationsProviders also cited their ability to provide quality care and technical difficulties as among their top frustrations with telehealth, a new survey shows.ByAnuja VaidyaMarch 18, 202...
Source: Australian Health Information Technology - March 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs