More on why we Stay Alive
A couple of days ago I referred to the doubling of human life expectancy in 100 years, and the importance of pasteurization of milk in making that happen. Our next installment is about water. There ' s nothing more basic than good old H2O, but it used to kill city dwellers about as often as milk. People actually figured this out even before Pasteur and Koch came up with the germ theory of disease.Cholera is an intestinal infection caused by a bacterium called Vibrio cholera, which is spread through contaminated water or food. The disease causes severe diarrhea that can last for several days. Depending on the strain of bact...
Source: Stayin' Alive - March 21, 2022 Category: American Health Source Type: blogs
What ’s wrong? Patients use disinformation to blame doctors.
“You were doing it wrong.” The patient in my pulmonary clinic for follow-up after her discharge from a hospitalization in January of this year for COVID-19 pneumonia was explaining why she would not reconsider getting vaccinated despite her recent illness. I told her I had been seeing people die from this disease for the lastRead more …What’s wrong? Patients use disinformation to blame doctors. originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 14, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/abhaya-p-trivedi" rel="tag" > Abhaya P. Trivedi, MD < /a > < /span > Tags: Physician COVID Infectious Disease Pulmonology Source Type: blogs
TWiV 874: COVID-19 clinical update #105 with Dr. Daniel Griffin
In COVID-19 clinical update #105, Daniel Griffin discusses changes in brain structure after infection, dementia in patients with pneumonia, Paxlovid in children, mask effectiveness in schools, host factors and severe disease, post-acute symptoms, and the mission of CEPI. Click arrow to playDownload TWiV 874 (49 MB .mp3, 41 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Show notes […] (Source: virology blog)
Source: virology blog - March 12, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody Omicron pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs
TWiV 872: COVID-19 clinical update #104 with Dr. Daniel Griffin
In COVID-19 clinical update #104, Daniel Griffin reviews effectiveness of mRNA vaccines among children, number of children affected by disease, accuracy of rapid antigen tests, CDC guidance for prevention strategies, monoclonal antibody effectiveness, predicting progression to severe respiratory failure from pneumonia, risk of long COVID after two vaccine doses, and peripheral neuropathy in long COVID. (Source: virology blog)
Source: virology blog - March 5, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid monoclonal antibody pandemic SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs
What the Pandemic Taught Us About Value-based Care
By RICHARD ISSACS
You’ll recall that we ran a long piece (pt 1, pt 2) about Medicare Advantage from former Kaiser Permanente CEO George Halvorson earlier this year. Here’s a somewhat related piece from the current head of the Permanente Medical Group about what actually happened there and elsewhere during the pandemic–Matthew Holt
The COVID-19 pandemic has provided important lessons regarding the structure and delivery of health care in the United States, and one of the most significant takeaways has been the need to shift to value-based models of care.
The urgency for this transformation was cle...
Source: The Health Care Blog - February 17, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Physicians Kaiser Permanente Medicare Advantage Pandemic Richard Isaacs value-based care Source Type: blogs
‘Just Follow the Science’ Shows Some Improvement
Peter Van DorenDuring summer 2020 I wrote anessay about what science can and cannot do and the role it can play in public policy decisions including those pertaining to the COVID-19 pandemic. I concluded that science explains relationships between cause and effect: no more and no less. No normative conclusions about individual or collective decisions follow directly from science. Instead, costs, benefits, and other values properly enter both individual and collective decisions.I have writtenthreetimessince then about gradual recognition of this argument among medical professionals as well as journalists. I a...
Source: Cato-at-liberty - February 16, 2022 Category: American Health Authors: Peter Van Doren Source Type: blogs
The importance of treating early treatment diseases
Today, the practice of medicine mainly involves treating medical conditions after symptoms of the medical condition become obvious (e.g., setting a fracture or treating pneumonia), or preventing disease for a population of patients using a preventative that has few side effects (e.g., vaccinations, mammograms). In the future, medicine will be more predictive and proactive. MedicineRead more …The importance of treating early treatment diseases originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 3, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/michael-r-mcguire" rel="tag" > Michael R. McGuire < /a > < /span > Tags: Conditions Primary Care Source Type: blogs
Funding Opportunities: The ARDS, Pneumonia, and Sepsis Phenotyping Consortium
We want the research community to know about two funding opportunity announcements (FOAs) that NIGMS has joined as part of an NHLBI initiative to support the formation of a multisite study, the Acute Respiratory Distress Syndrome (ARDS), Pneumonia, and Sepsis Phenotyping (APS) Consortium. The study seeks to better define the heterogeneity underlying critical illness syndromes and to identify the mechanisms of illness development and recovery, as well as relationships and overlap between these syndromes. The FOAs are:
RFA-HL-23-001, ARDS, Pneumonia, and Sepsis Phenotyping Consortium Clinical Centers (U01...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - February 2, 2022 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Sepsis Research Source Type: blogs
A brief note on epidemiology
Mark Sumner at DK has aroundup of news from overwhelmed health care systems around the country. This seems to be getting very little attention from national media, for some reason -- this is a list of local stories, which don ' t seem to have gotten the attention of editors at CNN or the New York Times.This is definitely bad news in the present, but it ' s better news in the long run. The Covid-19 variant that ' s causing this is extremely contagious -- as contagious a measles, apparently. That means you can become infected just by briefly being in the vicinity of an infectious person. One thing that ' s really unpleasant ...
Source: Stayin' Alive - January 8, 2022 Category: American Health Source Type: blogs
What does LBBB look like in severe hypothermia? Is there a long QT? Is the QT appropriate for the temperature?
This patient was found down in a Minneapolis winter. He was very cold with frostbitten fingers and toes. He was alert but encephalopathic and delirious and very agitated and could not be adequately calmed with olanzapine and lorazepam, so we intubated him. The first reliable temperature could only be obtained with a Foley thermistor, and it was 26.5 degrees C (79.7 F).His BP was 76/60. K was 2.8 mEq/L.Here was his first ECG:There is sinus bradycardia with left bundle branch block (LBBB), with proportional ST-T, and VERY long QT and a PVC. I measure the QT at 800 ms. Notice that there are ...
Source: Dr. Smith's ECG Blog - January 6, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs
Epidemics and pandemics (2): AIDS
Just over 40 years ago, in June 1981, a paper appeared in Morbidity and Mortality Weekly Report (MMWR) describing an opportunistic lung infection in otherwise healthy gay men. The lung condition was pneumocystis pneumonia, and this was the first description of what came to be known as AIDS. That first description, first article, was a case series, of five people, and therefore not evidence from particularly high up the traditional evidence pyramid. I may have pointed this out to students when discussing evidence based practice and that pyramid.There is more about this inthis post from Circulatin...
Source: Browsing - December 29, 2021 Category: Databases & Libraries Tags: AIDS Source Type: blogs
O2Ring Keeps an Eye on Your Blood Oxygen Level: A Medgadget Review
Conclusion
We found O2Ring to be a convenient, easy-to-use pulse oximeter. It is a particularly appealing option for medical conditions that require prolonged monitoring of blood oxygen levels, such as sleep apnea, chronic lung disease, and more recently, COVID-19 pneumonia.
O2Ring can be purchased from Wellue’s official website and Amazon. It retails for $165, which is slightly above the price point of other comparable products. Nevertheless, the device may offer peace of mind to both users and their loved ones.
Product page: O2Ring Oximeter Continuous Ring Oxygen Monitor
Related flashbacks: Smart Ring ...
Source: Medgadget - December 27, 2021 Category: Medical Devices Authors: Kenan Raddawi Tags: Cardiology Diagnostics Exclusive Sports Medicine Source Type: blogs
Test Detects SARS-CoV-2 in Breath, May Work as COVID Alarm in Enclosed Spaces
Researchers at Brown University have developed a breath test for COVID-19. The breathalyzer, which they have termed the Bubbler, consists of a tube that someone blows into for fifteen seconds. The tube contains a mix of enzymes that reverse transcribe the RNA in viral particles into DNA, which allows for a subsequent benchtop PCR test.
Breathalyzers were bathed in UV light to maintain sterile field prior to construction of kits prepared for the clinical trial at Rhode Island Hospital. Top image: Bubbler kits were processed in a negative pressure bench top box to prevent contamination of amplicon particles in the labora...
Source: Medgadget - December 20, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Public Health brown university Source Type: blogs
Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated.
Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity
Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Oral Bacteria and Age-Related Airway Inflammation
Researchers have in the past proposed links between oral bacteria and chronic inflammation, particularly in the heart and brain, proposing that bacterial toxins and bacteria themselves enter the bloodstream via damaged gums. This undoubtedly happens, but supporting data is mixed when it comes to the question of whether or not this has a meaningful effect size in comparison to other inflammatory mechanisms and contributions to age-related disease. Here, a different route for bacteria is proposed: passage into the airways and lungs, a possibly explanation as why gum disease and respiratory mortality are correlated in older p...
Source: Fight Aging! - November 29, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
