Further polycyclic quinones of Micromonospora sp
Chem Biodivers. 2024 Apr 16:e202301771. doi: 10.1002/cbdv.202301771. Online ahead of print.ABSTRACTThe crude acetone extract of a marine Micromonospora sp. strain associated with Eudistoma vannnamei was fractioned with hexane and ethyl acetate. The crude extract and both soluble fractions were assayed against several bacteria strains. The new polycyclic quinones 12-hydroxy-9-propyltetracene-6,1-dione (1), 5,12-dihydroxy-4-methoxy-9-propyltetracene-5,12-dione (2), and 4,6-dihydroxy-3-methoxycarbonyl- methyl-6a-(oxobutyl)-5,12-anthraquinone (3), along with the known 4,6-dihydroxy-3-methoxycarbonyl-methyl-6a-(oxo-3-methyl-but...
Source: Chemistry and Biodiversity - April 17, 2024 Category: Biochemistry Authors: Otilia Deusdenia Loiola Pessoa Hozana Patricia Silva de Freitas Ces ário Francisco das Chagas Lima Pinto Kirley Marques Canuto Ediberto Rocha Silveira Diego Veras Wilke Elthon Gois Ferreira Alu ísio Marques da Fonseca Mayron Alves de Vasconcelos Edson H Source Type: research

Further polycyclic quinones of Micromonospora sp
Chem Biodivers. 2024 Apr 16:e202301771. doi: 10.1002/cbdv.202301771. Online ahead of print.ABSTRACTThe crude acetone extract of a marine Micromonospora sp. strain associated with Eudistoma vannnamei was fractioned with hexane and ethyl acetate. The crude extract and both soluble fractions were assayed against several bacteria strains. The new polycyclic quinones 12-hydroxy-9-propyltetracene-6,1-dione (1), 5,12-dihydroxy-4-methoxy-9-propyltetracene-5,12-dione (2), and 4,6-dihydroxy-3-methoxycarbonyl- methyl-6a-(oxobutyl)-5,12-anthraquinone (3), along with the known 4,6-dihydroxy-3-methoxycarbonyl-methyl-6a-(oxo-3-methyl-but...
Source: Chemistry and Biodiversity - April 17, 2024 Category: Biochemistry Authors: Otilia Deusdenia Loiola Pessoa Hozana Patricia Silva de Freitas Ces ário Francisco das Chagas Lima Pinto Kirley Marques Canuto Ediberto Rocha Silveira Diego Veras Wilke Elthon Gois Ferreira Alu ísio Marques da Fonseca Mayron Alves de Vasconcelos Edson H Source Type: research

Burden of antimicrobial prescribing in primary care attributable to sore throat: a retrospective cohort study of patient record data
CONCLUSIONS: Frequency of antibiotic prescribing for sore throat is high and broad, despite Australian Therapeutic guideline recommendations. Multiple, sustained interventions to reduce prescribing, including availability of effective S. pyogenes vaccines that could reduce the incidence of streptococcal pharyngitis, could obviate the need to prescribe antibiotics and support ongoing efforts to promote antimicrobial stewardship.PMID:38632513 | PMC:PMC11022400 | DOI:10.1186/s12875-024-02371-y (Source: Primary Care)
Source: Primary Care - April 17, 2024 Category: Primary Care Authors: Kylie S Carville Niamh Meagher Yara-Natalie Abo Jo-Anne Manski-Nankervis James Fielding Andrew Steer Jodie McVernon David J Price Source Type: research

In vitro antibacterial activity of antibiotics and plant essential oils against Escherichia coli MTCC443 supported through the molecular docking and pharmacokinetics study
This study has been made to compare the in vitro antibacterial activity and further validated the same through the molecular docking study of 13 antibiotics such as ciprofloxacin, chloramphenicol, erythromycin, ampicillin, cefotaxime, rifampicin, kanamycin, vancomycin, streptomycin, penicillin, nalidixic acid, trimethoprim, and polymyxin, and 10 EOs such as garlic, tulsi, neem, clove, thyme, peppermint, coriander, tea, lavender, and eucalyptus against the target protein (DNA gyrase) ofE. coli MTCC443.E. coli Microbial Type Culture Collection 443 was found to be highly sensitive to ciprofloxacin (zone of inhibition [ZOI], 2...
Source: Biotechnology and Applied Biochemistry - April 17, 2024 Category: Biochemistry Authors: Saurabh Jain, Adarsh Kumar Shukla, Surbhi Panwar, Rajesh Kumar, Ashwani Kumar Tags: ORIGINAL ARTICLE Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Pain Physician)
Source: Pain Physician - April 16, 2024 Category: Anesthesiology Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research