A single cell atlas of sexual development in Plasmodium falciparum | Science
The developmental decision made by malaria parasites to become sexual underlies all malaria transmission. Here, we describe a rich atlas of short- and long-read single-cell transcriptomes of over 37,000 Plasmodium falciparum cells across ... (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research
Zombie malaria parasites | Science
Natural infections are distinct from those of laboratory —or zombie—strains (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research
The Transmission of Animal African Trypanosomiasis in Two Districts in the Forest Zone of Ghana
Am J Trop Med Hyg. 2024 May 2:tpmd230329. doi: 10.4269/ajtmh.23-0329. Online ahead of print.ABSTRACTAnimal African trypanosomiasis, also known as nagana, is caused by Trypanosoma species, which cause significant clinical diseases and lead to losses in animal production. We carried out a cross-sectional survey to investigate the composition of vectors and parasite diversity in two districts in the eastern region of Ghana where pigs and cattle were exposed to tsetse bites. We performed cytochrome c oxidase subunit 1 polymerase chain reaction (PCR) to identify tsetse species and internal transcribed spacer 1 PCR to identify T...
Source: The American Journal of Tropical Medicine and Hygiene - May 2, 2024 Category: Tropical Medicine Authors: Austine Tweneboah Jana Rosenau Kofi Agyapong Addo Thomas Kwame Addison Mahamat Alhadj Moussa Ibrahim Judith Sophie Weber Soerge Kelm Kingsley Badu Source Type: research
Soil-Transmitted Helminth Infections in Shanghai, China: Surveillance from 2014 to 2023
Am J Trop Med Hyg. 2024 May 2:tpmd230910. doi: 10.4269/ajtmh.23-0910. Online ahead of print.ABSTRACTSoil-transmitted helminthiasis remains a notable health problem in developing countries. In 1990 in Shanghai, a city in eastern China, 47% of the population was affected. Due to a series of comprehensive approaches, the prevalence decreased to 0.5% in 2009. We collected 10-year surveillance data to assess the epidemic situation of soil-transmitted helminth (STH) infections in Shanghai. Stool samples and questionnaires from participants were collected. The Kato-Katz technique was used to detect infections with Ascaris lumbric...
Source: The American Journal of Tropical Medicine and Hygiene - May 2, 2024 Category: Tropical Medicine Authors: Simin Dai Yaoguang Zhang Lei Shen Huijie Yao Zhenyu Wang Yibin Zhou Jiawei Yang Zixin Wei Min Zhu Huanyu Wu Jian Chen Qing Yu Source Type: research
Comparative proteomics analysis of samples from hepatic cystic echinococcosis patients using data-independent acquisition approach
This study aimed to assess the specific proteins that are potential candidates for the development of a vaccine against E. granulosus. The data-independent acquisition approach was employed to identify differentially expressed proteins (DEPs) in E. granulosus samples. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was employed to identify several noteworthy proteins. Results: The DEPs in E. granulosus samples were identified (245 pericystic wall vs. parasite-free yellowish granuloma (PYG, 1725 PY vs. PYG, 2274 PN vs. PYG). Further examination of these distinct proteins...
Source: Journal of Proteomics - May 2, 2024 Category: Biochemistry Authors: Kahaer Tuerxun Rong-Hua Tang Aabudouxikuer Abudoumijiti Zainuer Yusupu Aizemaiti Aikebaier Salamu Mijiti Irshat Ibrahim Yan-Long Cao Abudoukeyimu Yasheng Yuan-Quan Wu Source Type: research
Anemia and Associated Factors among Public Elementary School Children in Asella Town, Southeast Ethiopia: A Facility-Based Cross-Sectional Study
CONCLUSION: Anemia among school-age children was found to be a mild public health problem. Uneducated mothers, intestinal parasite infections, and underweight children were found to be determinants of anemia among school-age children. Health professionals should provide health education for mothers about child-feeding practices and the consumption of dietary sources of iron.PMID:38694783 | PMC:PMC11062769 | DOI:10.1155/2024/1519382 (Source: Anemia)
Source: Anemia - May 2, 2024 Category: Hematology Authors: Ararso Hordofa Guye Kasim Hansa Kasahun Ketema Meseret Moroda Dame Banti Shambi Source Type: research
Green synthesized silver nanoparticles of < em > Terminalia bellirica < /em > leaves extract: synthesis, characterization, < em > in-silico < /em > studies, and antimalarial activity
In conclusion, this novel class of AgNPs may be used as a potential therapeutic replacement for the treatment of malaria.PMID:38696111 | DOI:10.1080/21691401.2024.2339429 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - May 2, 2024 Category: Biotechnology Authors: Sujeet Singh Hemant Arya Welka Sahu K Sony Reddy Surendra Nimesh Bader Saud Alotaibi Mohammed Ageeli Hakami Hassan H Almasoudi Khater Balatone Gezira Hessien Mohammad Raghibul Hasan Summya Rashid Tarun Kumar Bhatt Source Type: research
Soil-Transmitted Helminth Infections in Shanghai, China: Surveillance from 2014 to 2023
Am J Trop Med Hyg. 2024 May 2:tpmd230910. doi: 10.4269/ajtmh.23-0910. Online ahead of print.ABSTRACTSoil-transmitted helminthiasis remains a notable health problem in developing countries. In 1990 in Shanghai, a city in eastern China, 47% of the population was affected. Due to a series of comprehensive approaches, the prevalence decreased to 0.5% in 2009. We collected 10-year surveillance data to assess the epidemic situation of soil-transmitted helminth (STH) infections in Shanghai. Stool samples and questionnaires from participants were collected. The Kato-Katz technique was used to detect infections with Ascaris lumbric...
Source: Am J Trop Med Hyg - May 2, 2024 Category: Infectious Diseases Authors: Simin Dai Yaoguang Zhang Lei Shen Huijie Yao Zhenyu Wang Yibin Zhou Jiawei Yang Zixin Wei Min Zhu Huanyu Wu Jian Chen Qing Yu Source Type: research
The Transmission of Animal African Trypanosomiasis in Two Districts in the Forest Zone of Ghana
Am J Trop Med Hyg. 2024 May 2:tpmd230329. doi: 10.4269/ajtmh.23-0329. Online ahead of print.ABSTRACTAnimal African trypanosomiasis, also known as nagana, is caused by Trypanosoma species, which cause significant clinical diseases and lead to losses in animal production. We carried out a cross-sectional survey to investigate the composition of vectors and parasite diversity in two districts in the eastern region of Ghana where pigs and cattle were exposed to tsetse bites. We performed cytochrome c oxidase subunit 1 polymerase chain reaction (PCR) to identify tsetse species and internal transcribed spacer 1 PCR to identify T...
Source: Am J Trop Med Hyg - May 2, 2024 Category: Infectious Diseases Authors: Austine Tweneboah Jana Rosenau Kofi Agyapong Addo Thomas Kwame Addison Mahamat Alhadj Moussa Ibrahim Judith Sophie Weber Soerge Kelm Kingsley Badu Source Type: research
A longer-chain acylated derivative of Dictyostelium differentiation-inducing factor-1 enhances the antimalarial activity against Plasmodium parasites
In this study, we synthesised DIF-1(+3) (1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl) nonan-1-one). We then evaluated the effects of DIF-1(+3) in vitro on Plasmodium falciparum and in vivo over 7 days (50-100 mg/kg/day) in a mouse model of Plasmodium berghei. DIF-1(+3) exhibited a half-maximal inhibitory concentration of approximately 20-30 % of DIF-1(+2) in three laboratory strains with a selectivity index > 263, including in strains resistant to chloroquine and artemisinin. Parasite growth and multiplication were almost completely suppressed by treatment with 100 mg/kg DIF-1(+3). The survival time of infected mice w...
Source: Biochemical Pharmacology - May 2, 2024 Category: Drugs & Pharmacology Authors: Naoko Yoshida Haruhisa Kikuchi Makoto Hirai Betty Balikagala Denis A Anywar Hikari Taka Naoko Kaga Yoshiki Miura Naoyuki Fukuda Emmanuel I Odongo-Aginya Yuzuru Kubohara Toshihiro Mita Source Type: research
Soil-Transmitted Helminth Infections in Shanghai, China: Surveillance from 2014 to 2023
Am J Trop Med Hyg. 2024 May 2:tpmd230910. doi: 10.4269/ajtmh.23-0910. Online ahead of print.ABSTRACTSoil-transmitted helminthiasis remains a notable health problem in developing countries. In 1990 in Shanghai, a city in eastern China, 47% of the population was affected. Due to a series of comprehensive approaches, the prevalence decreased to 0.5% in 2009. We collected 10-year surveillance data to assess the epidemic situation of soil-transmitted helminth (STH) infections in Shanghai. Stool samples and questionnaires from participants were collected. The Kato-Katz technique was used to detect infections with Ascaris lumbric...
Source: The American Journal of Tropical Medicine and Hygiene - May 2, 2024 Category: Tropical Medicine Authors: Simin Dai Yaoguang Zhang Lei Shen Huijie Yao Zhenyu Wang Yibin Zhou Jiawei Yang Zixin Wei Min Zhu Huanyu Wu Jian Chen Qing Yu Source Type: research
The Transmission of Animal African Trypanosomiasis in Two Districts in the Forest Zone of Ghana
Am J Trop Med Hyg. 2024 May 2:tpmd230329. doi: 10.4269/ajtmh.23-0329. Online ahead of print.ABSTRACTAnimal African trypanosomiasis, also known as nagana, is caused by Trypanosoma species, which cause significant clinical diseases and lead to losses in animal production. We carried out a cross-sectional survey to investigate the composition of vectors and parasite diversity in two districts in the eastern region of Ghana where pigs and cattle were exposed to tsetse bites. We performed cytochrome c oxidase subunit 1 polymerase chain reaction (PCR) to identify tsetse species and internal transcribed spacer 1 PCR to identify T...
Source: The American Journal of Tropical Medicine and Hygiene - May 2, 2024 Category: Tropical Medicine Authors: Austine Tweneboah Jana Rosenau Kofi Agyapong Addo Thomas Kwame Addison Mahamat Alhadj Moussa Ibrahim Judith Sophie Weber Soerge Kelm Kingsley Badu Source Type: research
Anemia and Associated Factors among Public Elementary School Children in Asella Town, Southeast Ethiopia: A Facility-Based Cross-Sectional Study
CONCLUSION: Anemia among school-age children was found to be a mild public health problem. Uneducated mothers, intestinal parasite infections, and underweight children were found to be determinants of anemia among school-age children. Health professionals should provide health education for mothers about child-feeding practices and the consumption of dietary sources of iron.PMID:38694783 | PMC:PMC11062769 | DOI:10.1155/2024/1519382 (Source: Anemia)
Source: Anemia - May 2, 2024 Category: Hematology Authors: Ararso Hordofa Guye Kasim Hansa Kasahun Ketema Meseret Moroda Dame Banti Shambi Source Type: research
Comparative proteomics analysis of samples from hepatic cystic echinococcosis patients using data-independent acquisition approach
This study aimed to assess the specific proteins that are potential candidates for the development of a vaccine against E. granulosus. The data-independent acquisition approach was employed to identify differentially expressed proteins (DEPs) in E. granulosus samples. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was employed to identify several noteworthy proteins. Results: The DEPs in E. granulosus samples were identified (245 pericystic wall vs. parasite-free yellowish granuloma (PYG, 1725 PY vs. PYG, 2274 PN vs. PYG). Further examination of these distinct proteins...
Source: Journal of Proteomics - May 2, 2024 Category: Biochemistry Authors: Kahaer Tuerxun Rong-Hua Tang Aabudouxikuer Abudoumijiti Zainuer Yusupu Aizemaiti Aikebaier Salamu Mijiti Irshat Ibrahim Yan-Long Cao Abudoukeyimu Yasheng Yuan-Quan Wu Source Type: research
Green synthesized silver nanoparticles of < em > Terminalia bellirica < /em > leaves extract: synthesis, characterization, < em > in-silico < /em > studies, and antimalarial activity
In conclusion, this novel class of AgNPs may be used as a potential therapeutic replacement for the treatment of malaria.PMID:38696111 | DOI:10.1080/21691401.2024.2339429 (Source: Artificial Cells, Nanomedicine and Biotechnology)
Source: Artificial Cells, Nanomedicine and Biotechnology - May 2, 2024 Category: Biotechnology Authors: Sujeet Singh Hemant Arya Welka Sahu K Sony Reddy Surendra Nimesh Bader Saud Alotaibi Mohammed Ageeli Hakami Hassan H Almasoudi Khater Balatone Gezira Hessien Mohammad Raghibul Hasan Summya Rashid Tarun Kumar Bhatt Source Type: research
