Outcomes of SDHB pathogenic variant carriers: A systematic review and meta-analysis
CONCLUSION: Penetrance for PPGL in SDHB PV carriers increases linearly with age. Affected carriers are at risk of developing and dying from metastatic disease, or of developing second tumors. Lifelong surveillance is appropriate.PMID:38605204 | DOI:10.1210/clinem/dgae233 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 11, 2024 Category: Endocrinology Authors: Dahlia F Davidoff Richard De Abreu Lourenco Venessa H M Tsang Diana E Benn Roderick J Clifton-Bligh Source Type: research
Cancers, Vol. 16, Pages 1466: Long-Term Surgical Outcome of Class A and B Tympanomastoid Paragangliomas
Conclusions: Tympanomastoid PGL represents the most common neoplasm of the middle ear space. The most frequent presenting symptoms include pulsatile tinnitus and hearing loss, whereas the presence of retrotympanic mass was evident in all cases at the time of initial otoscopic evaluation. Proper documentation of facial function and audiometric evaluation are crucial elements of preoperative workup. The most preferred preoperative radiologic examination is high-resolution computer tomography (HRCT), whereas magnetic resonance imaging (MRI) with or without gadolinium enhancement is reserved for cases with a dilemma of carotid...
Source: Cancers - April 11, 2024 Category: Cancer & Oncology Authors: Melcol Hailu Yilala Giuseppe Fancello Virginia Fancello Lorenzo Lauda Mario Sanna Tags: Article Source Type: research
Reply to “comments on tumor progression in tympanojugular paragangliomas: the role of radiotherapy and wait and scan”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 9, 2024 Category: ENT & OMF Source Type: research
Thorough examination of the potential biological implications of the cuproptosis-related gene LIPT2 in the prognosis and immunotherapy in pan-cancer
CONCLUSION: Overall, our study highlights LIPT2 as a versatile player in cancer, influencing diverse aspects from molecular processes to clinical outcomes across different cancer types.PMID:38586090 | PMC:PMC10994786 | DOI:10.62347/QNNE5428 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - April 8, 2024 Category: Research Authors: Mi Luo Abdul Rehman Soha Haque Saba Izhar Fauzia Perveen Muhammad Haris Mostafa A Abdel-Maksoud Ibrahim A Saleh Naser Zomot Abdul Malik Abdulaziz Alamri Ahmad S Kodous Mohammed Aufy Mohamed Y Zaky Muhammad Zaeem Yasir Hameed Junwei Li Source Type: research
