Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma - A retrospective multi-center cohort study
CONCLUSIONS: We demonstrate in a real-life clinical setting that all current therapies show reasonable efficacy in preventing disease progression, and this is equally true for patients with germline SDHB mutations.PMID:37949483 | DOI:10.1093/ejendo/lvad146 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - November 10, 2023 Category: Endocrinology Authors: Alessa Fischer Simon Kloos Hanna Remde Ulrich Dischinger Christina Pamporaki Henri J L M Timmers Mercedes Robledo Stephanie M J Fliedner Katharina Wang Julian Maurer Astrid Reul Nicole Bechmann Constanze Hantel Hermine Mohr Natalia S Pellegata Stefan R Bo Source Type: research
The inferior performance of [ < sup > 68 < /sup > Ga]Ga-FAPI-04 PET/CT as a diagnostic and theranostic biomarker in [ < sup > 177 < /sup > Lu]Lu-DOTATATE refractory well-differentiated neuroendocrine tumors
CONCLUSION: Our preliminary results demonstrated that [68Ga]Ga-FAPI-04 PET/CT mainly failed in well-differentiated NETs refractory to [177Lu]Lu-DOTATATE therapy and had a limited role as an alternative diagnostic or theranostic agent. Further investigations with a larger patient population are required to determine the impact of [68Ga]Ga-FAPI-04 PET/CT on NETs.PMID:37947850 | DOI:10.1007/s00259-023-06497-6 (Source: Molecular Medicine)
Source: Molecular Medicine - November 10, 2023 Category: Molecular Biology Authors: Duygu Has Simsek Yunus Guzel Dilara Denizmen Yasemin Sanli Fikret Buyukkaya Bilal Kovan Halil Komek Emine Goknur Isik Zeynep Gozde Ozkan Serkan Kuyumcu Source Type: research
Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma - A retrospective multi-center cohort study
CONCLUSIONS: We demonstrate in a real-life clinical setting that all current therapies show reasonable efficacy in preventing disease progression, and this is equally true for patients with germline SDHB mutations.PMID:37949483 | DOI:10.1093/ejendo/lvad146 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - November 10, 2023 Category: Endocrinology Authors: Alessa Fischer Simon Kloos Hanna Remde Ulrich Dischinger Christina Pamporaki Henri J L M Timmers Mercedes Robledo Stephanie M J Fliedner Katharina Wang Julian Maurer Astrid Reul Nicole Bechmann Constanze Hantel Hermine Mohr Natalia S Pellegata Stefan R Bo Source Type: research
The inferior performance of [68Ga]Ga-FAPI-04 PET/CT as a diagnostic and theranostic biomarker in [177Lu]Lu-DOTATATE refractory well-differentiated neuroendocrine tumors
ConclusionOur preliminary results demonstrated that [68Ga]Ga-FAPI-04 PET/CT mainly failed in well-differentiated NETs refractory to [177Lu]Lu-DOTATATE therapy and had a limited role as an alternative diagnostic or theranostic agent. Further investigations with a larger patient population are required to determine the impact of [68Ga]Ga-FAPI-04 PET/CT on NETs. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 10, 2023 Category: Nuclear Medicine Source Type: research
Resection of a lumbar intradural tumor
CONCLUSION: Early intervention and gross total resection of spinal intradural tumors are associated with optimal patient outcomes. Additional adjuncts, such as ultrasound, are beneficial and can help achieve gross total tumor resection.PMID:37941626 | PMC:PMC10629344 | DOI:10.25259/SNI_770_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - November 9, 2023 Category: Neurosurgery Authors: Joseph Yunga Tigre Andrew J Kloehn Ava Scemama James Boddu Meredith C Costello Allan D Levi S Shelby Burks Source Type: research
