Weaponizing the Biochemistry of Huntington's Disease as a General Cancer Therapy
An interesting observation that has arisen over the years of epidemiological study of human age-related disease is that there are a number of distinct inverse relationships between incidence of cancer and incidence of some forms of neurodegeneration. This was in the news a few years ago in the case of Alzheimer's disease for example. Why would people with a higher risk of cancer suffer lower rates of Alzheimer's disease, however? We can only speculate at this point, but the more recent discovery I'll point out here adds fuel for that speculation. The Alzheimer's-cancer relationship is modest in size and somewhat complex in...
Source: Fight Aging! - February 14, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Intermountain Precision Genomics to Develop Hereditary Cancer Gene Panels
The emerging healthcare model which is dominated by a small number of very large health systems will be characterized, in part, by in-house, sophisticated genomic and molecular lab testing by these systems. This is because these large health systems will have the capital to invest in their own"laboratories of excellence" within their system. Such is the case withIntermountain Healthcare which has its own in-house genomics laboratory called Intermountain Precision Genomics. Intermountain Health is one of the giant health systems with 37,000 employees, 22 hospitals, and more than 185 clinics. Here is the miss...
Source: Lab Soft News - February 13, 2018 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Clinical Lab Industry News Clinical Lab Testing Genomic Testing Healthcare Business Healthcare Innovations Lab Industry Trends Lab Processes and Procedures Medical Consumerism Pathology Informatics Reference Laboratories Test Kits and Source Type: blogs
Genetic Testing and Non-High Risk
A person can be considered medically high risk due to their or a family member ' s medical history. If you are considered medically as high risk, you get popped into the category of give them lots more medical attention and ' lovely ' tests.Now withthe progress of genomic testing, its no longer a big expensive, rare proposition. However, why do we only test the high risk people? These are the people who already know they are high risk. But that leaves a lot of people who don ' t know they are high risk and could be. This doesn ' t make sense. Some new research asks if it wouldn ' t it make more sense to test more peop...
Source: Caroline's Breast Cancer Blog - February 10, 2018 Category: Cancer & Oncology Tags: breast cancer cancer prevention genetic testing ovarian cancer Source Type: blogs
Thank you Dr Malpani !
Febuary 8, 2018Dear Dr. Malpani,The following is my testimonial to how you and your lovely wife and staff were instrumental in transforming my life b...
Source: Dr.Malpani's Blog - February 10, 2018 Category: Reproduction Medicine Source Type: blogs
Where Next for Cellular Reprogramming and Regenerative Medicine?
Over the past decade researchers have gained ever more expertise in reprogramming cells from one type to another. The most useful form of reprogramming devised so far is the change from normal differentiated somatic cell, fixed in its role, to pluripotent stem cell, capable of generating any type of cell given the right instructions. Surprising recent developments in this line of research include (a) evidence that performing this transformation in a living animal is beneficial rather than cancerous, producing effects similar to those resulting from a stem cell transplant, and (b) that reprogramming cells to pluripotency er...
Source: Fight Aging! - February 2, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
I am glad patients are learning to say No !
A patient send me this emailSir, I m having a chocolate cyst in my left ovary of 3.6*2.8 CM and a normal right ovary . My first doctor advice me for immediate laparoscopy. I am trying for around 10 months. I changed my doc as I was scared of surgery. Can you help ?I am glad patients are speaking up and refusing to subject themselves to unnecessary surgery !With today's technology, infertile patients do not need a laparoscopy, but doctors continue to do this for them, without any good reason. Read more athttp://www.drmalpani.com/knowledge-center/infertility-testing/laparoscopy-and-infertilitySuch a tiny chocolate cyst will ...
Source: Dr.Malpani's Blog - January 30, 2018 Category: Reproduction Medicine Source Type: blogs
Misusing PRP ( Platelet Rich Plasma) treatment for "treating" infertility
Infertile couples are desperate, and many IVF doctors are happy to take undue advantage of this, in order to maximise their income.The latest racket is the use of PRP, or platelet rich plasma. This is supposed to contain stem cells, which have " miraculous " properties, which can treat anything and everything ! After all, stems cells are magical - they can transform themselves into any kind of cell in the body, because they are the original progenitor cells !This is why andrologists now inject PRP into the testes of hapless infertile men with testicular failure, to " help them" to produce sperm; and gynecologis...
Source: Dr.Malpani's Blog - January 26, 2018 Category: Reproduction Medicine Source Type: blogs
Fight Aging! Newsletter, January 22nd 2018
In conclusion, death is a natural part of human existence, but human progress is essentially a story of overcoming undesirable natural limits. In the near future, technological progress might make it possible to stop natural biological death. Should humankind embrace such technology? Yes: Even though such technology would not be without risks, the risks are almost certainly manageable. The benefits of ending natural death, on the other hand, are immense. Death is an obstacle that is slowing down human progress. If we remove that obstacle, humankind could increase the speed of both its moral and its epistemic progress.
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Source: Fight Aging! - January 21, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Early Detection
We do regularly try to detect some cancers early through mammograms, colonoscopies, and PSA tests. I think most of us (meaning the general public) are comfortable with these tests as we age. But what if there was a genetic test available which you could have done regularly, every few years or whatever time frame, to test you for several different cancers before they had a chance to spread.A new test,CancerSEEK, has been tested on more than 1000 patients and seems very hopeful." The CancerSEEK test looks for mutations in 16 genes that regularly arise in cancer and eight proteins that are often released.It was trialled on 1,...
Source: Caroline's Breast Cancer Blog - January 20, 2018 Category: Cancer & Oncology Tags: cancer detection cancer diagnosis medical tests Source Type: blogs
Remembering the Late Professor Juergen Willmann
Esteemed and highly innovative researcher and Stanford University professor of radiology Juergen Willmann, MD, died in a car accident on January 8. He was 45 years-old. Originally from Germany, Willmann spearheaded research using microbubbles and ultrasound that could be used to identify tumors and target the transmission of medication. His work was already being implemented in clinical imaging trials with humans to detect breast and ovarian cancer. He also won the 2017 Distinguished Investigator Award from the Academy for Radiology& Biomedical Imaging Research. Not only revered for his pioneering accomplishments, Will...
Source: radRounds - January 19, 2018 Category: Radiology Authors: Julie Morse Source Type: blogs
Recent Papers on the Mitochondrial Contribution to Aging
Mitochondria are the power plants of the cell, a herd of self-replicating structures evolved from ancient symbiotic bacteria, now fully integrated into the cell. Their primary task is the production of chemical energy stores, an energetic process that produces damaging reactive molecules as a side-effect. Much of the original bacterial DNA of the distant ancestors of today's mitochondia has migrated to the cell nucleus, leaving only a tiny remnant genome in the mitochondria themselves. When looking across species with widely divergent life spans, researchers have found good correlations between species life span and some c...
Source: Fight Aging! - January 16, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
What ’s the latest on estrogen use in post-menopausal women?
Estrogen is a miracle drug for many women who experience the drenching sweats, sexual dysfunction and frustrating brain betrayals associated with entering menopause. It comes in expensive patches, less expensive pills or injections, as well as vaginal creams or rings. It has gone in and out of favor with the medical community for decades.
Estrogen is the main ingredient in most birth control pills and has been studied extensively in that context as well as in the setting of women whose ovaries have ceased to produce it as they age. It can increase the risk of migraines, blood clots in the legs or lungs; it can cause benign...
Source: Kevin, M.D. - Medical Weblog - January 11, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/janice-boughton" rel="tag" > Janice Boughton, MD < /a > Tags: Conditions OB/GYN Source Type: blogs
LITFL Review 314
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 314th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
The Bottom Line has a comprehensive review on the role of steroids in sepsis – where w...
Source: Life in the Fast Lane - January 7, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
Fight Aging! Newsletter, January 1st 2018
Discussion of advocacy for the cause is a usual feature of our community, as we try things and attempt to make progress in persuading the world that rejuvenation research is plausible, practical, and necessary. There are more people engaged in advocacy now than at any time in the past decade, and so discussions of strategy come up often. New ventures kicked off in 2017 include the Geroscience online magazine, and among the existing ventures the LEAF / Lifespan.io volunteers seem to be hitting their stride. The mainstream media continues to be as much a hindrance as a help, and where it is a help you will usually find Aubre...
Source: Fight Aging! - December 31, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Look Back at the Science of Longevity and Advocacy for Rejuvenation in 2017
Discussion of advocacy for the cause is a usual feature of our community, as we try things and attempt to make progress in persuading the world that rejuvenation research is plausible, practical, and necessary. There are more people engaged in advocacy now than at any time in the past decade, and so discussions of strategy come up often. New ventures kicked off in 2017 include the Geroscience online magazine, and among the existing ventures the LEAF / Lifespan.io volunteers seem to be hitting their stride. The mainstream media continues to be as much a hindrance as a help, and where it is a help you will usually find Aubre...
Source: Fight Aging! - December 29, 2017 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
