A glimpse into the fragile balance of life and death in the ICU
It was a calm and quiet night in the ICU during my rotation when suddenly, the piercing sound of a code blue alarm filled the air. An elderly female patient, 66 years old, had come in earlier with lung clots due to ovarian cancer. She was on the other side of the hospital, and as
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A glimpse into the fragile balance of life and death in the ICU originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 8, 2023 Category: General Medicine Authors: Ton La, Jr., MD, JD Tags: Physician Critical Care Source Type: blogs
Preventing Genetic Testing Fraud: 5 Actions for Health Plans
The following is a guest article by Erin Rutzler, Vice President of Fraud, Waste, and Abuse at Cotiviti
In Delaware, more than 250 Medicare patients underwent unnecessary genetic testing based on telehealth consultations that often lasted less than two minutes—costing Medicare thousands of dollars per patient. Meanwhile, an emerging scheme for fraudulent and unnecessary cardiovascular and cancer genetic testing allegedly resulted in $174 million in false and fraudulent Medicare claims.
These are just two examples of what the Healthcare Fraud Prevention Partnership describes as a surge in fraud, waste and abuse associated...
Source: EMR and HIPAA - May 5, 2023 Category: Information Technology Authors: Guest Author Tags: Administration Genomics-Precision Medicine Health IT Company Healthcare IT Regulations Revenue Cycle Management Cotiviti CPT Codes Erin Rutzler Fraud Waste and Abuse FWA Genetic Testing Genetic Testing Fraud Healthcare Fraud Prev Source Type: blogs
Fight Aging! Newsletter, March 6th 2023
In this study, we develop a rFOXN1 fusion protein that contains the N-terminal of CCR9, FOXN1, and TAT. We show here that, when injected intravenously (i.v.) into aged mice, the rFOXN1 fusion protein can migrate into the thymus and enhance T cell generation in the thymus, resulting in increased number of peripheral T cells. Our results suggest that the rFOXN1 fusion protein has the potential to be used in preventing and treating T cell immunodeficiency in the older adult.
Increased miR-181a-5p Expression Improves Neural Stem Cell Activity, Learning, and Memory in Old Mice
https://www.fightaging.org/archives/20...
Source: Fight Aging! - March 5, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Ovarian Organoids to Study Reproductive Health
Researchers at the Harvard Wyss Institute are collaborating with a biotechnology company called Gameto to develop human ovarian organoids that will allow the study of reproductive and other health issues using tissues that closely mimic those in human patients. Another application may lie in allowing people with fertility issues to conceive. To date, ovarian organoids have been created using a mixture of human and mouse cells, which limits their relevance and translation to human disease. It is also a slow process to create such hybrid human/animal organoids.
This new approach involves using induced pluripotent stem cel...
Source: Medgadget - February 28, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Ob/Gyn Reproductive Medicine harvard wyssinstitute Source Type: blogs
The Extended Fertility of Naked Mole-Rats
Naked mole-rats exhibit few signs of aging across a life span. Only the queens bear young, but they can continue do so into old age. As this study notes, they achieve this feat via a number of mechanisms that ensure a continued supply of egg cells. This isn't just a matter of minimizing damage to these cells and their supporting tissues, but also generating new egg cells in adult life, unlike other mammals. It remains an open question as to whether there is any great realization yet to be found in this comparative biology that will benefit efforts to extend human fertility into later life. It doesn't hurt to look.
...
Source: Fight Aging! - February 28, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, January 23rd 2023
This study explored the association between tap drinking water and longevity in Cilento, Italy, to understand whether trace elements in local drinking water may have an influence on old, nonagenarian, and centenarian people and promote their health and longevity.
Data on population and water sources were collected through the National Demographic Statistics, the Cilento Municipal Archives, and the Cilento Integrated Water Service. Ordinary least squares (OLS) regression and a geographically weight regression (GWR) model were used to study the spatial relationship between the explanatory and outcome variables of long...
Source: Fight Aging! - January 22, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
ADAR1 in Immunity and Aging
This short overview skims recent work on the role of ADAR1 expression in aging. Levels of ADAR1 are reduced with age in many tissues, and this may affect a number of processes relevant to aging, such as cellular senescence. ADAR1 edits RNA, affecting the behavior of gene expression at a very low level. It is a good example of a protein that is thus involved in many, many processes in the cell, and which has indirect effects on any number of cell behaviors. It is exceptionally challenging to pin down specific important roles for such proteins. There is such a large space of possibilities to cover that decades of work may or...
Source: Fight Aging! - January 16, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Bonus Features – December 4, 2022 – 34% of Americans take anti-anxiety meds during the holidays, hospital margins at -2% but show signs of hope, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
Studies
A DrFirst survey of more than 1,000 Americans concluded that one-third of Americans have taken anti-anxiety medications to manage family stress during the holiday season. That’s significantly more than the 19% of A...
Source: EMR and HIPAA - December 4, 2022 Category: Information Technology Authors: Brian Eastwood Tags: Health IT Company Healthcare IT Amber Mauro AvaSure AvodahMed Baptist Health Benjamin Barlow Chris Kocsis Clear Arch Health David Roth DrFirst Emergence Health emtelligent emtelliSuite Experity Frank Bordonaro Gustave Rouss Source Type: blogs
Fight Aging! Newsletter, November 28th 2022
This study explored whether determining the gain or loss of specific taxa represent a more precise metric of healthy/unhealthy aging than summary microbiome statistics, such as diversity and uniqueness. We analyzed microbiome diversity and four measures of microbiome uniqueness in 21,000 gut microbiomes for their relationship with aging and health. We show that diversity and uniqueness measures are not synonymous; uniqueness is not a uniformly desirable feature of the aging microbiome, nor is it an accurate biomarker of healthy aging. Different measures of uniqueness show different associations with diversity and with mark...
Source: Fight Aging! - November 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
IGF1 Gene Therapy as a Neuroprotective Treatment, Slowing Female Reproductive Aging
Researchers here describe an interesting approach to slowing aspects of neurodegeneration that contribute to, among other things, female reproductive aging. That is the focus of this paper, but numerous other aspects of the aging brain are also involved. IGF1 is well studied in the context of aging, and manipulation of the signaling pathways linking insulin, IGF1, and growth hormone has been shown to extend life span in a number of species. Where we can make direct comparisons between mice and humans, such as between growth hormone receptor knockout mice and humans with Laron syndrome, the effects are nowhere near as large...
Source: Fight Aging! - November 23, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
I Have To Say I Really Do Find This App Pretty Worrying As It Is At Present
This appeared
last week:
App: Tracking menses and
more for endo, adeno and PCOS patients
Siobhan Calafiore
9 November 2022
Unlike most period apps available, QENDO not
only helps patients track their menstrual cycle, pain and mood but is also a
tool to manage chronic illness.
It is aimed at people with endometriosis, adenomyosis and polycystic ovarian
syndrome who are after an easy way to (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - November 18, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Weekly Overseas Health IT Links – 22nd October, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment-----https://mhealthintelligence.com/news/partnership-to-add-virtual-primary-care-feature-to-smart-tvsPartnership to Add Virtual Primary Care Feature to Smart TVsTelehealth provider HealthTap has partnered with Samsung to add a virtual healthcare feature to the tech giant ' s Smart TVs to expand access to primary care.ByMark MelchionnaOctober 14, 2022 - Aiming to ...
Source: Australian Health Information Technology - October 22, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Pathfinder 2022: faster, further and fairer
This report shows that although there have been significant improvements over the years for women with ovarian cancer, not enough progress has been made in diagnosis, awareness, treatment and support. It reveals that if diagnosis was faster, further support was available and access to treatment was fairer, there could be potential for more women to survive, live well with ovarian cancer and be supported from diagnosis and throughout treatment.ReportPress release (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - October 20, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: Quality of care and clinical outcomes Source Type: blogs
Fight Aging! Newsletter, September 19th 2022
Conclusion
Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life.
Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
In the Matter of Human Longevity There Will Be Opportunists and Alchemists
I suspect that a sizable, earnest community of opportunists and alchemists focused on anti-aging and longevity will continue to exist even as we transition from an era in which the only approaches to aging (beyond exercise and calorie restriction) were snake oil, the only service providers frauds, to an era in which therapies to slow aging and produce rejuvenation actually exist and are robustly proven to do what they say on the label. Will reliable, low-cost ways to measure biological age drive out the true believers who try whatever intervention is hyped, fail to gain scientific understanding, and fail to use adequate me...
Source: Fight Aging! - September 16, 2022 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
