Is there any connection between Grade C embryos and the risk of birth defects ?
A patient asked me this question.Can Grade A embryos result in abnormalities in the baby ? Or do only Grade C results in abnormalities ? Sadly, there is still a lot of misunderstanding  about embryo grading . Most embryologists are not skilled enough to be able to grade embryos properly, and because many IVF specialists have never set foot in the lab , they don't really understand what embryo grades mean. And if the IVF doctor is so confused, it's hardly surprising that patients are completely in the dark.Embryo grades are basically lab shorthand for describing the appearance of the embryo - how it looks under th...
Source: Dr.Malpani's Blog - May 26, 2018 Category: Reproduction Medicine Source Type: blogs

The limits of IVF technology
The IVF lab is the heart of IVF treatment. We keep your eggs and sperms safely in the incubator, and your embryos grow in the IVF culture medium in vitro, until they form good quality blastocysts, which are ready to either be frozen , or to be transferred into your uterus.The most important thing an IVF lab does is make sure there are no toxic elements within the culture medium or the laboratory , as these could damage the growth of your embryos. We want to keep them happy, so they thrive in vitro, until they are ready to go back into your uterus !However, sadly there is very little we can do to actually enhance the growth...
Source: Dr.Malpani's Blog - May 25, 2018 Category: Reproduction Medicine Source Type: blogs

World's first infertility Chatbot !
We have created the world's first infertility chatbot, to help infertile patients learn more about their problem.Naima is an intelligent digital medical assistant, who will help you find what you need to know !Check her out atwww.ivfindia.comThis is a beta release, and your feedback will help us enormously in improving how she answers your  queries ! Please be kind - this is a work in progress (Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - May 25, 2018 Category: Reproduction Medicine Source Type: blogs

The difference between IVF outputs and IVF outcomes - what every patient needs to know !
What every patient ( and every doctor) wants from every IVF cycle is a happy ending -  a baby. It's great when we can achieve this happy outcome, but sadly IVF does not have a 100% pregnancy rate, which means many IVF cycles fail.While this is heartbreaking, the patient then needs to plan what to do next, and this is why it's so important to differentiate between output and outcome.The output is the end-result of the IVF treatment , and this is something which a doctor can control. This is tangible, in the form of top quality blastocysts.However, once we transfer the blastocyst back into the uterus, we have no control...
Source: Dr.Malpani's Blog - May 24, 2018 Category: Reproduction Medicine Source Type: blogs

How can we make IVF more affordable in India ?
I often see lots of infertile patients who could get pregnant if they did IVF treatment. Unfortunately, they just cannot afford to do an IVF cycle for financial reasons, and they end up without a baby. It fair to say  that  this causes them a significant amount of  frustration and heartburn when you know that IVF can help you get pregnant; but you can ’t, because you just can’t afford the treatment.Can this be changed? But it ’s not just the patients who are affected; IVF specialists also go through a lot of anguish when this happens. It’s very difficult to come to terms with the...
Source: Dr.Malpani's Blog - May 19, 2018 Category: Reproduction Medicine Source Type: blogs

Why didn't this blastocyst implant ?
The truthful answer is - We don't know !This doesn't mean we are stupid or ignorant - it just means medical technology has its limitations, and we need to learn to live with them, by having realistic expectations of what IVF treatment can accomplish - and what it can't !So what do we know ?We know that human reproduction is not a very efficient process, and that most embryos will not implant because they have genetic abnormalities we still cannot test for. This is the limitation of IVF technology today, and we need to come to terms with it.The problem is that patients are unhappy when the doctor tells them the truth, becau...
Source: Dr.Malpani's Blog - May 18, 2018 Category: Reproduction Medicine Source Type: blogs

What do we need to change for our next IVF cycle
After her IVF cycle failed, a patient sent me this emailIn retrospect what do you think could have gone wrong? Is there anything I need to improve or change ? It's important to learn from each IVF cycle by analysing what went, and what didn't. The right time to do this is at the time of embryo transfer, because it is only until this point that we have any control. We can only three tangible variables -embryo qualityendometrial ( receptivity) thickness and texturethe ease of the transferOnce the embryos have been transferred into the uterus, we have no ability to check what happens inside the uterus. All we know is tha...
Source: Dr.Malpani's Blog - May 17, 2018 Category: Reproduction Medicine Source Type: blogs

IVF failure - incompetence ? or bad luck ?
IVF failure can be the result of bad luck , or sometimes the result of the IVF doctor's incompetence . The key question the patient wants an answer to is - How do I differentiate between the two ? Did my cycle fail in spite of the fact that the doctor did everything right " Or did it fail because the doctor wasn't able to make good embryos in the lab ?The only way to answer this question is by getting photos of your embryos , and doing enough homework so you are able to interpret the images of your embryos . The good news is that this is easy to do - and if you need help, please feel free to email me !You can see...
Source: Dr.Malpani's Blog - May 16, 2018 Category: Reproduction Medicine Source Type: blogs

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IVF failure can be the result of bad luck , or sometimes the result of the IVF doctor's incompetence . The key question the patient wants an answer to is - How do I differentiate between the two ? Did my cycle fail in spite of the fact that the doctor did everything right " Or did it fail because the doctor wasn't able to make good embryos in the lab ?The only way to answer this question is by getting photos of your embryos , and doing enough homework so you are able to interpret the images of your embryos . The good news is that this is easy to do - and if you need help, please feel free to email me !You can see...
Source: Dr.Malpani's Blog - May 16, 2018 Category: Reproduction Medicine Source Type: blogs

How to prevent errors in IVF - what every patient needs to know !
The biggest nightmare for any IVF patient is that the lab may mix up their eggs and sperms with another patients. This has happened in many clinics, and IVF is as prone to errors as any other treatment because it is provided by a host of people working together – doctors, nurses, receptionist, ultrasonographers, lab technicians and embryologists. It requires lots of coordination, and there are few treatment processes for which a team approach is more important than for assisted reproduction. Close, continuous communication is required at many levels to e nsure everything goes as planned.Communication mattersAll of th...
Source: Dr.Malpani's Blog - May 15, 2018 Category: Reproduction Medicine Tags: IVF error IVF mistakes Source Type: blogs

IVF for treating recurrent miscarriages
Recurrent pregnancy loss ( repeated miscarriages or habitual abortions) is one of the most frustrating problems in medicine. It is hard for patients , because getting pregnant , and then losing the baby again and again is traumatic. It's bad for doctors, because patients have so many questions , and we don't have any answers ! The truth is that our tests are not very good, and there is little we can do to make n accurate a diagnosis. This is why, in about 80% of patients with recurrent pregnancy loss , inspite of extensive testing, we will not be able to find an underlying cause.Based on experience over many years, the one...
Source: Dr.Malpani's Blog - May 14, 2018 Category: Reproduction Medicine Tags: IVF miscarriage recurrent abortions recurrent miscarriage recurrent pregnancy loss Source Type: blogs

Second opinions for IVF patients
While second opinions can be quite helpful in reducing " avoidable medical care" , they come with their own set of challenges. . Patients are scared about seeking out a second opinion because they are worried that by doing so, the doctor who is treating them will get offended and may disengage himself from the treatment. Patients are scared of physicians and don't want to risk antagonizing them!The two sides of the coin1. Not all second opinions are correct. Sometimes, it's the "first opinion" which might have been the right decision for the patient, and only time is able to tell which doctor ...
Source: Dr.Malpani's Blog - May 12, 2018 Category: Reproduction Medicine Tags: IVF expert IVF second opinion Source Type: blogs

How many IVF cycles will it take for me to get pregnant ?
There are some questions which IVF doctors cannot answer accurately, and one of these is the commonest questions patients ask - How many IVF cycles will it take for me to get pregnant?Patients know that IVF doesn't have a 100% pregnancy rate and that they need to be patient. They are prepared to repeat the cycles, and this is a perfectly valid question to ask , because this helps them to prepare mentally and financially for a journey which can be taxing and stressful.However, the frustrating reality is doctors can't answer this simple query accurately for the individual patient. Yes , we can provide group statistics and of...
Source: Dr.Malpani's Blog - May 11, 2018 Category: Reproduction Medicine Source Type: blogs

Why a picture is worth a 1000 words in an IVF cycle !
This is why patients should always insist that their IVF clinic provide them with photos of their embryos. This helps to keep the IVF clinic honest !Good clinics provide embryo photos routinely and proactively, because they are transparent, open and accountable. Sadly, not all clinics do this as yet - and this is why patients should be assertive. The best time is before you start your IVF cycle and have paid your charges - otherwise you will be fobbed off with all kinds of lame excuses . The worst one I have heard is a complete lie - " We don't take photos because this will damage the embryos !"The trut...
Source: Dr.Malpani's Blog - May 10, 2018 Category: Reproduction Medicine Tags: blast blastocyst photos blastocysts embryo photos ivf IVF cycle Source Type: blogs

Root cause analysis for IVF failure
 We treat lots of engineers and computer programmers who are infertile , and when their IVF cycle fails, they ask us, "Can we please do a root cause analysis to find out why the cycle failed?"After all, they are engineers and think logically and analytically. They want definitive answers , and are upset when we can't provide these. Root cause analysis works extremely well when you're dealing with inanimate objects, but unfortunately, what applies to machines cannot be extrapolated to human beings.This doesn't mean that doctors are illogical or lazy - it just means that our technology has limitations, and we ...
Source: Dr.Malpani's Blog - May 10, 2018 Category: Reproduction Medicine Source Type: blogs

Overdiagnosis in IVF - how some IVF clinics increase work for themselves.
Lots of IVF doctors are very trigger happy, and make a diagnosis which is completely inaccurate. For example, they will do an ultrasound scan for a patient on the fifth or sixth day of the cycle and notice at that time that the follicles are small or the endometrium is thin , and then tell her, "Oh, your thin endometrium means that you most probably have endometrial tuberculosis, and you need investigation and treatment for this." This is plainly ridiculous ! On Day 6, most fertile women will have small follicles , because they haven't started growing yet , as a result of which their estrogen levels are goin...
Source: Dr.Malpani's Blog - May 9, 2018 Category: Reproduction Medicine Tags: IVF diagnosis IVF misdiagnosis IVF overdiagnosis IVF tests Source Type: blogs

Feedback from a patient gladdens a doctor's heart
Due to my extreamly low AMH at 28,  I have done multiple cycle embryo pooling at the Malpani clinic and will begin my transfers soon. Dr Aniruddha not only guided me medically but also gave me a lot of motivation. Dr Anjali is very sympathetic, attentive and intuitive. I have taken consultations at various top clinics in Mumbai but the services offered by the Malpanis can't be compared with the rest. Unlike other doctors herein Dr Anjali performs all the ultrasounds herself followed by timely egg pick up and then transfers. They are one of the very few doctors in the city who have the confidence and the high...
Source: Dr.Malpani's Blog - May 8, 2018 Category: Reproduction Medicine Tags: ivf doctor IVF patient Malpani Malpani Clinic malpani IVF malpani review Source Type: blogs

Why do IVF doctors sing a different tune after the IVF cycle fails ?
Patients who have failed an IVF cycle often find that what their doctor told them at the time of the embryo transfer is very different from what they tell them after their IVF cycle fails. At the time of the transfer they are very optimistic , and gush about how great the embryos they have made for the patient in the lab are, and how she will definitely get pregnant!  Sadly, they don't provide any embryo photos, so the patient is forced to accept the doctor's word, since there is no documentation.However, when the cycle fails, the doctor comes up with all kinds of creative explanations , as the lining was thin ; ...
Source: Dr.Malpani's Blog - May 7, 2018 Category: Reproduction Medicine Tags: failed IVF failed IVF cycle IVF failure Source Type: blogs

How over-reporting on ultrasound scans harms infertile patients
Vaginal ultrasound is an extremely useful tool when evaluating an infertile woman, but it often bothers me because there are some sonographers who over interpret the scan images. Now, I like the fact that they are careful and systematic, and document everything they see by taking lots of images. However, I hate the fact that draw clinical conclusions based on the black and white images they see on the screen - and they shouldn't be doing this.Their reports will say things like, " There are adhesions between the ovary and the uterus"; " There is a 3 cm endometriotic cyst"; the fallopian tubes a...
Source: Dr.Malpani's Blog - May 7, 2018 Category: Reproduction Medicine Source Type: blogs

Why freezing all embryos is the IVF treatment of choice today
You can read the full text of the paper in  Human Reproduction at https://academic.oup.com/humrep/article/33/5/924/4925329It's chock full of medical jargon, but the message is quite clear !AbstractSTUDY QUESTIONWhat is the chance of having a child following one complete IVF cycle for patients using a freeze-all strategy?SUMMARY ANSWERThe chance of having a child after the first complete IVF cycle was 50.74% with the freeze-all strategy.WHAT IS KNOWN ALREADYSeveral studies have reported on live birth rates (LBRs) based on only the fresh embryo transfer cycle or fresh and frozen –thawed embryo transfer cycles...
Source: Dr.Malpani's Blog - May 5, 2018 Category: Reproduction Medicine Source Type: blogs

The right way to do a HSG
A HSG ( hysterosalpingogram, X-ray of the uterus and tubes is a very useful test to check if the uterine cavity is normal and the fallopian tubes are open. In this series of X-rays,  you can clearly see the dye entering the cavity; filling the cavity; and then entering the tubes, filling them, and then spilling out of the terminal ends. This is a normal HSG, showing that the tubes are patent ( normal fill and spill). Some of the plates are white on black , and this is because the radiologist has manipulated the image. You can also see that the dye seems to have collected in one place - what is called a loculation.The ...
Source: Dr.Malpani's Blog - May 5, 2018 Category: Reproduction Medicine Tags: HSG Hysterosalpingography Source Type: blogs

How IVF doctors create work for themselves !
A patient just sent me this emailI and my husband were trying to conceive for last 4 months but didn't get success. I went for normal fertility check up and was surprised to know that my AMH level was only 1.41. I was suggested to opt for IVF. Please suggest i should wait for normal conception or shall opt for IVF?Doctors seem to be happy to do IVF for anyone who walks into their clinic, and this kind of "treatment creep" leads to unnecessary overtreatment .While IVF is a great treatment, it should be restricted only to infertile couples who need it !For one thing, this couple is not even infertile. The definitio...
Source: Dr.Malpani's Blog - May 4, 2018 Category: Reproduction Medicine Source Type: blogs

Pregnancy testing during the 2ww
The 2ww is a " no woman's "land for most IVF patients.You know the embryo is inside your uterus, but you don't know if it's going to implant or not.Many patients think of themselves as being "partially pregnant" - and they know this makes no rational sense at all.They obsess night and day about what's happening to their embies - and are petrified that they may do something to harm them.Most can't wait for the result of the HCG blood test result, and will start doing HPTs as home - sometimes as soon a 3 days after the transfer.They then drive themselves sick with worry, and their husbands crazy with thei...
Source: Dr.Malpani's Blog - May 4, 2018 Category: Reproduction Medicine Tags: 2ww HCG HCG test HPT IVF 2ww Pregnancy test UPT Source Type: blogs

How doctors cause harm
A patient sent me this email.Hi doctor my wife had two miscarriages in last 18 months . After second miscarriage we have done TORCH test, it shows high range of of CMV IgG at 200 (normal range is 0-6) and CMV IgM is non reactive range (0.17) we had consult doctor he had given medicine valcivir for 20 days , after complete 20 days CMV  at IgG at 53 , we had stop taking medicine after 30 days when we have test CMV IgG shows again 194 level.My query is with this rising level of CMV igg how we conceive a healthy pregnancy ?I have searched on internet and it shows rising level of CMV IgG causes serious birth defect in baby...
Source: Dr.Malpani's Blog - May 3, 2018 Category: Reproduction Medicine Tags: abortions CMV miscarriages TORCH torch infections torch tests Source Type: blogs

What are diva donors in IVF clinics ?
Many patients who want to use donor eggs ask us if we have " diva " donors. Apparently, this is a popular term in many IVF clinics for donors with special traits - for example, they have " higher attributes " in terms of education and background . Now a diva is a prima donna  or celebrated female singer. Applying this to egg donors makes no medical sense to me at all.After all, family background ( whatever that means), IQ and education are not heritable traits , and are medically irrelevant . A patient should focus on getting good quality eggs from a healthy young fertile egg donor, who h...
Source: Dr.Malpani's Blog - May 2, 2018 Category: Reproduction Medicine Tags: diva donors donor egg Egg donation egg donor Source Type: blogs

Are we overlooking something doctor ?
A patient sent me this email after 2 failed IVF cycles at our clinicIt is frustrating, but i think we need to do a deep analysis to understand why things are not going the right way, if we plan to again go for this entire process of IVF. She had diligently followed all the instructions with regards to medicines , food and rest.  We do have some doubts in mind which i think you should be able to clear:1. Why isn ’t her body accepting the embryo ?2. Should there have been some more medicines administered to her for her body to accept foreign embryo?This was my replyThis kind of thinking is flawedThe uterus is pass...
Source: Dr.Malpani's Blog - May 2, 2018 Category: Reproduction Medicine Source Type: blogs

Having a baby makes for happier families !
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - May 2, 2018 Category: Reproduction Medicine Source Type: blogs

Why do IVF doctors blame patients when the lab messes up ?
A patient sent me this email.Our last IVF cycle failed. We had 3 euploid embryos after doing PGD. These were graded as 6AA, 6AA, and 5AA. We had planned to transfer only one of the 6AAs on a FET , but when it thawed it didn ’t look great. It was still alive but looked ‘grainey’ As the doctor said. So she transferred the other 6AA as well which also not looking great but still alive. Neither took. She now believes it to be an egg quality issue and embryo quality issue. Could that be since they tested out as euploi d? The patient send me photos of her embryos, and it was clear that they had died during...
Source: Dr.Malpani's Blog - May 1, 2018 Category: Reproduction Medicine Source Type: blogs

How IVF patients can deal with unwanted advice
Most women going through an IVF cycle are extremely well informed because they spend so much time on the internet reading up about the problem. Also, they have finally found an IVF doctor whom they're happy and comfortable with , who gives them all the medical advice they need and they are happy to follow this.However, just because they are infertile, it seems that everyone else has an opinion about what they should and should not be doing ! Just because they have been able to have a baby in their own bedroom, they think they are fertility experts, and are qualified to advice infertile couples !They tell them what pre...
Source: Dr.Malpani's Blog - April 29, 2018 Category: Reproduction Medicine Source Type: blogs

Does IVF cause premature births ?
This is a common concern many patients have.Please remember that IVF pregnancies are the same as natural pregnancies, so they aren't at increased risk of prematurity.It's not the IVF which causes the prematurity - it's the multiple pregnancies ( which are commoner in IVF because some IVF clinics transfer many embryos at a time) which increases the risk - after all, the uterus was designed to handle only one baby.This is why we suggest that patients transfer only a single embryo ! (Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 25, 2018 Category: Reproduction Medicine Source Type: blogs

How the overdiagnosis of TB harms infertile women
A patient sent me this emailI had Laparoscopy 4 months back, was diagnosed with TB PCR, and now I am 5 Weeks Pregnant. My concern is should I continue the medicines prescribed by the doctor? will it cause any birth defect in the baby if i consume the medication like cleft lip ? or will I lose the pregnancy if i don't have the medicines, please advise.These TB PCR tests are very unreliable ! They are plagued by the problem on false positives - read more about this at http://blog.drmalpani.com/2015/03/laboratory-tb-versus-genital-tb.htmlSadly, most gynecologists are routinely treating all their infertile patients with anti-T...
Source: Dr.Malpani's Blog - April 25, 2018 Category: Reproduction Medicine Source Type: blogs

Is it safe to travel when doing IVF?
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 19, 2018 Category: Reproduction Medicine Source Type: blogs

IVF cycles can provide invaluable information
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 19, 2018 Category: Reproduction Medicine Source Type: blogs

Why do IVF cycles fail ?
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 18, 2018 Category: Reproduction Medicine Source Type: blogs

What care should you take after your embryo transfer ?
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 18, 2018 Category: Reproduction Medicine Source Type: blogs

Why is IVF treatment so expensive?
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 14, 2018 Category: Reproduction Medicine Source Type: blogs

What Should Every Doctor Know About IVF !
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 14, 2018 Category: Reproduction Medicine Source Type: blogs

Should you be transferring fresh or frozen embryos ?
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 13, 2018 Category: Reproduction Medicine Source Type: blogs

Why do IVF cycles fail?
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 12, 2018 Category: Reproduction Medicine Source Type: blogs

How to select the right IVF clinic
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 11, 2018 Category: Reproduction Medicine Source Type: blogs

The unknown complications of IVF
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 11, 2018 Category: Reproduction Medicine Source Type: blogs

Seven steps of IVF
(Source: Dr.Malpani's Blog)
Source: Dr.Malpani's Blog - April 9, 2018 Category: Reproduction Medicine Source Type: blogs

Implantation dysfunction
When patients fail repeated IVF cycles, the "diagnosis" their doctor offers them is - Implantation Dysfunction .However, this is really just a waste paper basket diagnosis - it does not provide any useful actionable information . It's a mouthful, but it's just a description of the fact that their embryos have consistently failed to implant for an unknown reason.Making a diagnosis - and receiving one - often gives both patients and doctors a lot of comfort, because they feel that once they have been able to put a name to the problem, they will be able to tackle it better. Sadly, this is often just a delusion ! (So...
Source: Dr.Malpani's Blog - April 7, 2018 Category: Reproduction Medicine Source Type: blogs

Laparoscopy and IVF - before, after or never ?
Before referring a patient for IVF to an IVF clinic, many gynecologists will insist on doing a laparoscopy . They justify this using all kinds of pretexts. saying" We will get a chance to check your pelvis, so we can clip your tubes, if needed, or burn any endometriosis." Their justification is that doing this will improve the patient's chance of getting pregnant with IVF. This is false, but poor patients don't know any better. They feel that if they are going to spend so much money on IVF, they might as well spend a little bit more on the laparoscopy, if this will improve their IVF success rate !Removing small f...
Source: Dr.Malpani's Blog - April 5, 2018 Category: Reproduction Medicine Tags: diagnostic laparoscopy Endoscopy ivf operative laparoscopy Source Type: blogs

The 7 steps of IVF
IVF seems to be an extremely complicated procedure, and sometimes IVF doctors take perverse pleasure in mystifying it, because they like showing off their expertise. This is why IVF  patients are often completely confused about what to expect. Actually , it's very straightforward and logical, and if you understand this simple framework , you will be able to make sure your doctor's doing the right stuff for you. Remember that all we are doing in an IVF cycle is replicating what should have happened normally in the fallopian tubes - the only difference is that we are doing this in the test tube ! 1. First is t...
Source: Dr.Malpani's Blog - March 26, 2018 Category: Reproduction Medicine Source Type: blogs

Why measuring uterine blood flow is pointless in an IVF cycle
Lots of IVF specialists monitor uterine blood flow during an IVF cycle. They believe that this helps them to track uterine receptivity, and good flow correlates with implantation rates. This makes logical sense, which is why so many sonographers study uterine blood flow doppler wave forms and the PI ( pulsatility index)I think this is meaningless.The fact that the endometrium is growing to a thickness of 8 mm means that it is receiving adequate perfusion - how would it be able to grow without an adequate blood supply ?This is another one of those measurements which are of no clinical value - but are done simply because we ...
Source: Dr.Malpani's Blog - March 24, 2018 Category: Reproduction Medicine Source Type: blogs

Using the embryoscope to take IVF patients for a ride
Many IVF clinics claim to use an embryoscope to culture embryos in vitro. While this provides great video images of the developing embryos, it has not been proven to improve IVF pregnancy rates. However, patients are quite happy to pay extra for this, because the doctor claims this is the "latest advance", and that's fine.However, the tragedy is that these doctors actually are just fooling the poor patient, and they never use the embryoscope at all for them - they just claim to !This is because they refuse to give patients the video generated by the embryoscope ! The absence of the video is proof that the embryos...
Source: Dr.Malpani's Blog - March 20, 2018 Category: Reproduction Medicine Source Type: blogs

Mindless IVF overtesting
When an IVF cycle fails because of poor quality embryos, rather than acknowledge the fact that often the result for the poor quality embryos is a poor quality IVF lab, IVF doctors are happy to blame "abnormal genetics" as the cause for the embryo fragmentation.They then send the poor patient off on a wild goose chase, by ordering expensive tests such as karytotype   ( chromosomal studies) , sperm FISH, and sperm DNA fragmentation, even though these are completely pointless and useless.The truth is that most IVF doctors understand very little about the limitations of genetic tests, and are happy to pass ...
Source: Dr.Malpani's Blog - March 19, 2018 Category: Reproduction Medicine Source Type: blogs

What can we do differently in the next IVF cycle ?
When an IVF cycle fails, this is the commonest question which patients ask - What can we do differently next  time ?They naively believe that the fact that the cycle failed means something went "wrong", and if we identify and  " correct" this, the next cycle will succeed.This is why doctors do lots of tests; and propose lots of new and more "advanced" treatments, in order to improve the chances of a pregnancy.Here's a list of the tests which may be proposed , to allow the doctor to "investigate" the reason for the failed implantation in more detailsERATB PCRhysteroscopyAnti...
Source: Dr.Malpani's Blog - March 13, 2018 Category: Reproduction Medicine Source Type: blogs

Is my IVF doctor taking me for a ride ?
A patient sent me this email.I am going through an IVF cycle . Egg retrieval has already been done and as per the doctor's report , 10 embryos were formed.. Then we were told that instead of fresh ET , he will.go for frozen cycle , so that ovary comes to to.normalcy, and he started me on 21 days birth control pill. I am upset that he did not explain this to me before we started.This month in this cycle (as today is day 13) my endometrium has reached only till 6.5 wherein last month it was 9mm. Is this normal?If the transfer is not done in this cycle will there be a negative impact on my embryos due to prolonged freezing?Wh...
Source: Dr.Malpani's Blog - March 13, 2018 Category: Reproduction Medicine Source Type: blogs