Retracted: Effects of Omega-3 Polyunsaturated Fatty Acids on Cognitive Function after Splenectomy in Rats
Biomed Res Int. 2024 Mar 20;2024:9802612. doi: 10.1155/2024/9802612. eCollection 2024.ABSTRACT[This retracts the article DOI: 10.1155/2021/5513886.].PMID:38550186 | PMC:PMC10973251 | DOI:10.1155/2024/9802612 (Source: Biomed Res)
Source: Biomed Res - March 29, 2024 Category: Research Authors: BioMed Research International Source Type: research

Icosapent ethyl modulates circulating vascular regenerative cell content: The IPE-PREVENTION CardioLink-14 trial
CONCLUSIONS: IPE-PREVENTION CardioLink-14 provides the first translational evidence that IPE can modulate VR cell content and suggests a novel mechanism that may underlie the cardioprotective effects observed with IPE in REDUCE-IT.FUNDING: HLS Therapeutics provided the IPE in kind and had no role in the study design, conduct, analyses, or interpretation.PMID:38552629 | DOI:10.1016/j.medj.2024.03.009 (Source: Pain Physician)
Source: Pain Physician - March 29, 2024 Category: Anesthesiology Authors: Ehab Bakbak Aishwarya Krishnaraj Deepak L Bhatt Adrian Quan Brady Park Asaad I Bakbak Basel Bari Kristin A Terenzi Yi Pan Elizabeth J Fry Daniella C Terenzi Pankaj Puar Tayyab S Khan Ori D Rotstein C David Mazer Lawrence A Leiter Hwee Teoh David A Hess Su Source Type: research

Icosapent ethyl modulates circulating vascular regenerative cell content: The IPE-PREVENTION CardioLink-14 trial
CONCLUSIONS: IPE-PREVENTION CardioLink-14 provides the first translational evidence that IPE can modulate VR cell content and suggests a novel mechanism that may underlie the cardioprotective effects observed with IPE in REDUCE-IT.FUNDING: HLS Therapeutics provided the IPE in kind and had no role in the study design, conduct, analyses, or interpretation.PMID:38552629 | DOI:10.1016/j.medj.2024.03.009 (Source: Pain Physician)
Source: Pain Physician - March 29, 2024 Category: Anesthesiology Authors: Ehab Bakbak Aishwarya Krishnaraj Deepak L Bhatt Adrian Quan Brady Park Asaad I Bakbak Basel Bari Kristin A Terenzi Yi Pan Elizabeth J Fry Daniella C Terenzi Pankaj Puar Tayyab S Khan Ori D Rotstein C David Mazer Lawrence A Leiter Hwee Teoh David A Hess Su Source Type: research

Cardiovascular risk and inflammation in a population with autoimmune diseases: a narrative review
Juvenile Systemic Connective Tissue Diseases (JSCTD) are a heterogeneous group of chronic autoimmune diseases, associated with dyslipidemia and increased cardiovascular risk are related. Studies from the last 10 years, from 2013 to 2022, on lipid profiles in JSCTD were collected. Different studies on lipid profiles in children affected by JSCTD were selected, because the aim is to analyze the cardiovascular risk and the possibility of atherosclerosis in these patients in whom, sometimes, corticosteroid therapies and immunosuppressants increase the state of dyslipidemia. Several studies have shown that autoimmune diseases w...
Source: Frontiers in Immunology - March 28, 2024 Category: Allergy & Immunology Source Type: research

Relationship between fatty acid intake and aging: a Mendelian randomization study
CONCLUSIONS: Our research presents compelling evidence of a causal association between certain fatty acids and indicators of the aging process. In particular, MUFA and PUFA may play a role in slowing down the aging process, while SFAs may contribute to accelerated aging. These findings could have significant implications for dietary recommendations aimed at promoting healthy aging.PMID:38535988 | DOI:10.18632/aging.205674 (Source: Aging)
Source: Aging - March 27, 2024 Category: Biomedical Science Authors: Yuhua Chen Lian Yang Kui Wang Yu An Yuping Wang Ya Zheng Yongning Zhou Source Type: research

The omega-3 polyunsaturated fatty acid docosahexaenoic acid enhances NK-cell antitumor effector functions
In this study, we explored whether docosahexaenoic acid (DHA), a type of ω-3 PUFA, had an immunomodulatory role in promoting tumour growth in immunocompetent mice. The number of natural killer (NK) cells but not the number of T or B cells was decreased by DHA supplementation in various tissues under physiological conditions. Although the frequency and number of NK cells were comparable, IFN-γ production by NK cells in both the spleen and lung was increased in DHA-supplemented mice in the mouse B16F10 melanoma tumour model. Single-cell RNA sequencing (scRNA-seq) revealed that DHA promoted effector function and oxidative p...
Source: Cell Research - March 25, 2024 Category: Cytology Authors: Shuting Wu Hongyan Peng Songyang Li Lanlan Huang Xiangyu Wang Yana Li Yongjie Liu Peiwen Xiong Qinglan Yang Kunpeng Tian Weiru Wu Rongxi Pu Xiulan Lu Zhenghui Xiao Jian Yang Zhaoyang Zhong Yuan Gao Yafei Deng Youcai Deng Source Type: research

Biological assessment of the omega-3 status after omega-3 enriched dietary during an active seasonal performance on soccer players
Conclusionsn-3 PUFA-enriched dietary supplementation might alter blood omega-3 indices in soccer players during the season. (Source: BMC Sports Science, Medicine and Rehabilitation)
Source: BMC Sports Science, Medicine and Rehabilitation - March 22, 2024 Category: Sports Medicine Source Type: research

Diet, exercise, and supplements: what is their role in the management of the metabolic dysfunction-associated steatotic liver disease in children?
AbstractMetabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease (NAFLD), is the main cause of chronic liver disease in children and adolescents. Indeed, epidemiological studies have shown that MASLD affects up to 40% of children with obesity. Despite the recent approval of medications that target weight loss in adolescents that could have benefits on pediatric MASLD, lifestyle interventions, such as diet and exercise, remain the mainstay of our therapeutic approach. More specifically, studies on diet alone have focused on the possible role of carbohydrate or fa...
Source: Endocrine - March 22, 2024 Category: Endocrinology Source Type: research

Nonsurgical Treatment of Periodontitis in Menopausal Patients: A Randomized Control Trial
CONCLUSIONS: Menopausal women with periodontitis who take omega-3 fatty acid supplements in addition to SRP have better oral health. Significant improvements in clinical indicators and a notable decrease in AST levels within the GCF were observed. However, further research with larger cohorts and extended duration is needed to validate these findings and explain potential mechanisms. This trial is registered with NCT06254118.PMID:38510979 | PMC:PMC10954359 | DOI:10.1155/2024/6997142 (Source: Biomed Res)
Source: Biomed Res - March 21, 2024 Category: Research Authors: Hadir F Eldessouky Magda Marie Source Type: research

Potential Micronutrient Deficiencies in the First 1000 Days of Life: The Pediatrician on the Side of the Weakest
This study is to examine potential micronutrient deficiencies and any need for supplementation in children following specific diet plans in the first 1000 days of life.RECENT FINDINGS: Optimal nutrition in the first 1000 days of life has a lifelong positive impact on child development. Specific intrauterine and perinatal factors, pathological conditions, and dietary restrictions can represent potential risk factors for micronutrient deficiencies in the first 1000 days of life, which can have negative systemic consequences. Preterm and low-birth-weight infants are intrinsically at risk because of immature body systems. Chil...
Source: Epilepsy Curr - March 21, 2024 Category: Neurology Authors: Carol à Panzeri Luca Pecoraro Alice Dianin Andrea Sboarina Olivia C Arnone Giorgio Piacentini Angelo Pietrobelli Source Type: research

Potential Micronutrient Deficiencies in the First 1000 Days of Life: The Pediatrician on the Side of the Weakest
This study is to examine potential micronutrient deficiencies and any need for supplementation in children following specific diet plans in the first 1000 days of life.RECENT FINDINGS: Optimal nutrition in the first 1000 days of life has a lifelong positive impact on child development. Specific intrauterine and perinatal factors, pathological conditions, and dietary restrictions can represent potential risk factors for micronutrient deficiencies in the first 1000 days of life, which can have negative systemic consequences. Preterm and low-birth-weight infants are intrinsically at risk because of immature body systems. Chil...
Source: Epilepsy Curr - March 21, 2024 Category: Neurology Authors: Carol à Panzeri Luca Pecoraro Alice Dianin Andrea Sboarina Olivia C Arnone Giorgio Piacentini Angelo Pietrobelli Source Type: research

Potential Micronutrient Deficiencies in the First 1000 Days of Life: The Pediatrician on the Side of the Weakest
This study is to examine potential micronutrient deficiencies and any need for supplementation in children following specific diet plans in the first 1000 days of life.RECENT FINDINGS: Optimal nutrition in the first 1000 days of life has a lifelong positive impact on child development. Specific intrauterine and perinatal factors, pathological conditions, and dietary restrictions can represent potential risk factors for micronutrient deficiencies in the first 1000 days of life, which can have negative systemic consequences. Preterm and low-birth-weight infants are intrinsically at risk because of immature body systems. Chil...
Source: Epilepsy Curr - March 21, 2024 Category: Neurology Authors: Carol à Panzeri Luca Pecoraro Alice Dianin Andrea Sboarina Olivia C Arnone Giorgio Piacentini Angelo Pietrobelli Source Type: research

Potential Micronutrient Deficiencies in the First 1000 Days of Life: The Pediatrician on the Side of the Weakest
This study is to examine potential micronutrient deficiencies and any need for supplementation in children following specific diet plans in the first 1000 days of life.RECENT FINDINGS: Optimal nutrition in the first 1000 days of life has a lifelong positive impact on child development. Specific intrauterine and perinatal factors, pathological conditions, and dietary restrictions can represent potential risk factors for micronutrient deficiencies in the first 1000 days of life, which can have negative systemic consequences. Preterm and low-birth-weight infants are intrinsically at risk because of immature body systems. Chil...
Source: Epilepsy Curr - March 21, 2024 Category: Neurology Authors: Carol à Panzeri Luca Pecoraro Alice Dianin Andrea Sboarina Olivia C Arnone Giorgio Piacentini Angelo Pietrobelli Source Type: research

Relevant Aspects of Combined Protocols for Prevention of N(M)AFLD and Other Non ‐Communicable Diseases
Risk factors for metabolic dysfunction-associated fatty liver disease (MAFLD) development and main characteristics of the monotherapies and combined protocols preventing or treating the disease. AbstractObesity is a global health issue characterized by the excessive fat accumulation, leading to an increased risk of chronic noncommunicable diseases (NCDs), including metabolic dysfunction-associated fatty liver disease (MAFLD), which can progress from simple steatosis to steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Currently, there are no approved pharmacological protocols for prevention/treatment of M...
Source: Molecular Nutrition and Food Research - March 21, 2024 Category: Food Science Authors: Luis A. Videla, Rodrigo Valenzuela, Jessica Z úñiga‐Hernández, Andrea del Campo Tags: Review Source Type: research