Efficacy and safety of GSP301 nasal spray in children aged 6-11 with seasonal allergic rhinitis
CONCLUSION: GSP301 was well tolerated and efficacious for treating SAR symptoms in pediatric subjects and demonstrated a favorable safety profile.CLINICAL TRIAL REGISTRATION: NCT03463031.PMID:35926824 | DOI:10.1016/j.anai.2022.07.029 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 4, 2022 Category: Allergy & Immunology Authors: Bruce M Prenner Niran J Amar Frank C Hampel Cynthia F Caracta Wen Wu Source Type: research

Efficacy and safety of GSP301 nasal spray in children aged 6-11 with seasonal allergic rhinitis
CONCLUSION: GSP301 was well tolerated and efficacious for treating SAR symptoms in pediatric subjects and demonstrated a favorable safety profile.CLINICAL TRIAL REGISTRATION: NCT03463031.PMID:35926824 | DOI:10.1016/j.anai.2022.07.029 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 4, 2022 Category: Allergy & Immunology Authors: Bruce M Prenner Niran J Amar Frank C Hampel Cynthia F Caracta Wen Wu Source Type: research

Efficacy and safety of GSP301 nasal spray in children aged 6 to 11 years with seasonal allergic rhinitis
GSP301 nasal spray is a fixed-dose combination of the antihistamine olopatadine hydrochloride and the corticosteroid mometasone furoate. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 1, 2022 Category: Allergy & Immunology Authors: Bruce M. Prenner, Niran J. Amar, Frank C. Hampel, Cynthia F. Caracta, Wen Wu Tags: Original Article Source Type: research

Efficacy and safety of GSP301 nasal spray in children aged 6-11 with seasonal allergic rhinitis
GSP301 nasal spray is a fixed-dose combination of the antihistamine olopatadine hydrochloride and the corticosteroid mometasone furoate. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - August 1, 2022 Category: Allergy & Immunology Authors: Bruce M. Prenner, Niran J. Amar, Frank C. Hampel, Cynthia F. Caracta, Wen Wu Tags: Original Article Source Type: research

The short-term effects of intranasal steroids on intraocular pressure in pediatric population
ConclusionSince children have greater risk for steroid-induced ocular hypertensive response than adults, ophthalmologic evaluation must be recommended in children receiving intranasal steroids. (Source: International Ophthalmology)
Source: International Ophthalmology - July 12, 2022 Category: Opthalmology Source Type: research

Clinical Efficacy of Tuomin Zhiti Decoction in Allergic Rhinitis
This study aimed to assess the efficacy of the Tuomin Zhiti decoction in allergic rhinitis and to provide a reference for clinical treatment. One hundred patients with AR treated in the Department of Otolaryngology of our hospital from January 2019 to December 2020 were recruited and assigned via a random number table method (1 : 1) to receive either oral loratadine and mometasone nasal spray (control group) or the Tuomin Zhiti decoction plus oral loratadine and mometasone nasal spray (study group). The total clinical efficacy was 86% (43/50) in the study group, which was significantly higher than that of 64% (32/50) in th...
Source: Evidence-based Complementary and Alternative Medicine - July 1, 2022 Category: Complementary Medicine Authors: Jian-Xin Zhang Wen-Yan Wang Source Type: research

Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research

Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research

Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research

Pharmacokinetic Evidence of Steady and Sustained Drug Release from Long-Acting Implantable Corticosteroid Matrices for Chronic Rhinosinusitis
CONCLUSION: LYR-210 achieved dose-dependent, continuous local MF delivery at a steady rate with low systemic exposure for months.PMID:35708181 | DOI:10.1177/19458924221107200 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - June 16, 2022 Category: ENT & OMF Authors: Randall A Ow Steven Shotts Venkata Kakarlapudi John McIntyre Robert M Naclerio Changcheng You Alexander Pappas Lindsay Brayton Yina Kuang James Shao Source Type: research