Therapeutic efficacy observation of Tuina manipulation for pediatric adenoid hypertrophy
ConclusionTuina manipulation is effective in treating pediatric AH, and produces a better effect in improving traditional Chinese medicine symptoms and QOL than 0.05% mometasone furoate nasal spray. (Source: Journal of Acupuncture and Tuina Science)
Source: Journal of Acupuncture and Tuina Science - December 1, 2021 Category: Complementary Medicine Source Type: research
Indacaterol acetate, glycopyrronium bromide, and mometasone furoate: effect on human airway inflammation
Conclusions: The synergy elicited by IND/MF and IND/GLY/MF combinations prevented the release of cytokines, with the concentrations of MF modulating the anti-inflammatory effects in passively sensitized bronchi. These data may explain the efficacy of IND/MF and IND/GLY/MF observed in clinical studies. (Source: European Respiratory Journal)
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Rogliani, P., Ritondo, B. L., Facciolo, F., Nikolaev, I., Calzetta, L. Tags: Airway pharmacology and treatment Source Type: research
Indacaterol acetate, glycopyrronium bromide, and mometasone furoate: effect on neuronal inflammation and acetylcholine release
Conclusions: IND/MF and IND/GLY/MF combinations modulated neuronal inflammation in a synergistic manner, but only IND/GLY/MF combination reduced the release of non-neuronal ACh. These observations may explain the efficacy of IND/MF and IND/GLY/MF observed in clinical studies. (Source: European Respiratory Journal)
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Rogliani, P., Ritondo, B. L., Facciolo, F., Matera, M. G., Nikolaev, I., Calzetta, L. Tags: Airway pharmacology and treatment Source Type: research
Clinically Meaningful Improvement in Total Rhinoconjunctivitis Score with Olopatadine/mometasone Combination Nasal Spray in Patients with Seasonal Allergic Rhinitis: A Pooled Analysis
The objective of this pooled analysis was to demonstrate the clinically meaningful effect of GSP301, a nasal spray combination of olopatadine hydrochloride (OLO) and mometasone furoate (MF), in treating both nasal and ocular symptoms of seasonal allergic rhinitis (SAR).Results were pooled from 3 double-blind, randomized, placebo-controlled 14-days studies. Patients (12-65 years, n=2,971) with SAR were equally randomized to twice-daily GSP301 (OLO 665 μg/MF 25 μg), OLO (665 μg), MF (25 μg), or placebo. Reflective total of 7 symptom scores (rT7SS, 4 rhinitis + 3 ocular symptoms) were determined. Mean %change from...
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Meltzer, E. O., Wu, W., Christensen, A. D., Wheeler, J., Aggarwal, V., Caracta, C. Tags: Airway pharmacology and treatment Source Type: research
