Varicella-Zoster Virus Encephalitis in an Immunocompetent Adult with Disseminated Cutaneous Herpes Zoster after Testosterone Booster Supplements: Case Report
We report a 28-year-old male who initially presented to the dermatology clinic with pinprick sensation over the right side of his face that was followed by vesicular eruption. Upon which he was diagnosed with herpes zoster and discharged on topical mupirocin ointment three times a day for 7 days and valacyclovir 1 g oral three times a day. A few hours later, he presented to the emergency department with drowsiness and an episode of loss of consciousness. He was then admitted by neurology and found to have herpetic encephalitis. During admission, he was started on intravenous acyclovir 10 mg/kg three times a day. After 3 we...
Source: Herpes - August 11, 2022 Category: Infectious Diseases Authors: Ghada Alhayaza Abdullah Al-Omair Hind M Almohanna Source Type: research

Varicella-Zoster Virus Encephalitis in an Immunocompetent Adult with Disseminated Cutaneous Herpes Zoster after Testosterone Booster Supplements: Case Report
We report a 28-year-old male who initially presented to the dermatology clinic with pinprick sensation over the right side of his face that was followed by vesicular eruption. Upon which he was diagnosed with herpes zoster and discharged on topical mupirocin ointment three times a day for 7 days and valacyclovir 1 g oral three times a day. A few hours later, he presented to the emergency department with drowsiness and an episode of loss of consciousness. He was then admitted by neurology and found to have herpetic encephalitis. During admission, he was started on intravenous acyclovir 10 mg/kg three times a day. After 3 we...
Source: Herpes - August 11, 2022 Category: Infectious Diseases Authors: Ghada Alhayaza Abdullah Al-Omair Hind M Almohanna Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Staphylococcal Scalded Skin Syndrome, Identification, and Wound Care: A Case Report Series
We present a case series of 3 preterm infants with SSSS receiving care at a level 3 neonatal intensive care unit.PRIMARY DIAGNOSIS: The infants presented with symptoms of sepsis, including temperature instability, apnea, and bradycardia episodes. The infants had peeling skin at sites of external pressure, including peripheral intravenous (IV) sites, under dressings, or where devices had been in contact with skin.INTERVENTIONS: The infants were soaked in a tub with gel baby wash and water to remove leads without traumatizing the skin. Laboratory values were drawn, and cultures were obtained. Wound care was provided using mu...
Source: Advances in Neonatal Care - July 28, 2022 Category: Nursing Authors: Katherine E McKeown Rachel B Baker Source Type: research

Molecules, Vol. 27, Pages 4613: Formulation of Chrysomycin A Cream for the Treatment of Skin Infections
Xuanrong Sun Chrysomycin A, a compound derived from marine microorganisms, proved to have a specific great in vitro inhibitory effect on methicillin-resistant Staphylococcus aureus (MRSA). It exhibits high safety for the skin, as well as a better therapeutic effect than the current clinical drug, vancomycin. Nevertheless, its poor water solubility highly limits the application and reduces the bioavailability. In view of this, we developed a cream of chrysomycin A (CA) to enhance the solubility for the treatment of skin infection, while avoiding the possible toxicity caused by systemic administration. A comprehensive...
Source: Molecules - July 19, 2022 Category: Chemistry Authors: Haohua Liu Yue Cai Yuteng Chu Xiaojie Yu Fuhang Song Hong Wang Huawei Zhang Xuanrong Sun Tags: Article Source Type: research

Flavaspidic acid BB combined with mupirocin improves its anti-bacterial and anti-biofilm activities against Staphylococcus epidermidis
The increase in drug-resistant opportunistic pathogenic bacteria, especially of antibiotic-resistant Staphylococcus epidermidis (S. epidermidis), has led to difficulties in the treatment of skin and soft tissue i... (Source: BMC Microbiology)
Source: BMC Microbiology - July 15, 2022 Category: Microbiology Authors: Zhiling Cai, Zitong Mo, Shiqian Zheng, Shihua Lan, Shengjun Xie, Jinghui Lu, Chunping Tang and Zhibin Shen Tags: Research Source Type: research

Accelerative effect of nanohydrogels based on chitosan/ZnO incorporated with citral to heal the infected full-thickness wounds; an experimental study
Int J Biol Macromol. 2022 Jul 9:S0141-8130(22)01462-3. doi: 10.1016/j.ijbiomac.2022.07.038. Online ahead of print.ABSTRACTAntimicrobial-resistant is a major challenge in to treat infected wounds, and new formulations should be produced. Citral (Citl), chitosan (Chsn), and zinc oxide (ZnO) nanoparticles may accelerate the wound healing process in terms of their antibacterial properties. This new study aimed to investigate the effects of ointments produced from ZnO/Chsn/Citl nanoparticles (NPs) to treat the infected wounds. Following the preparation of ZnO/Chsn/Citl-NPs, swelling behavior, the release of citral, toxicity, an...
Source: International Journal of Biological Macromolecules - July 12, 2022 Category: Biochemistry Authors: Omidreza Raei Abbasabadi Mohammad Reza Farahpour Zohreh Ghazi Tabatabaei Source Type: research

Calcium alginate/PNIPAAm hydrogel with body temperature response and great biocompatibility: Application as burn wound dressing
In this study, we used N-isopropyl acrylamide, sodium alginate and calcium chloride as the main materials, a series of calcium alginate/ poly (N-isopropyl acrylamide)(NIPAAm) hydrogel (CAPH) with different component ratios were synthesized. Its swelling properties, temperature response properties, rheological properties, biocompatibility properties, and in vitro drug release properties were investigated. Based on the above conditions, the CAPH(sodium alginate:NIPAAm = 2:15) with the best comprehensive performance was selected, which has a good biocompatibility. In addition, 0.02 % (w/v) mupirocin was loaded in CAPH. The te...
Source: International Journal of Biological Macromolecules - July 11, 2022 Category: Biochemistry Authors: Guoguang Chen Yaxin Zhou Jie Dai Shiyu Yan Wenjun Miao Lili Ren Source Type: research

Calcium alginate/PNIPAAm hydrogel with body temperature response and great biocompatibility: Application as burn wound dressing
In this study, we used N-isopropyl acrylamide, sodium alginate and calcium chloride as the main materials, a series of calcium alginate/ poly (N-isopropyl acrylamide)(NIPAAm) hydrogel (CAPH) with different component ratios were synthesized. Its swelling properties, temperature response properties, rheological properties, biocompatibility properties, and in vitro drug release properties were investigated. Based on the above conditions, the CAPH(sodium alginate:NIPAAm = 2:15) with the best comprehensive performance was selected, which has a good biocompatibility. In addition, 0.02 % (w/v) mupirocin was loaded in CAPH. The te...
Source: International Journal of Biological Macromolecules - July 11, 2022 Category: Biochemistry Authors: Guoguang Chen Yaxin Zhou Jie Dai Shiyu Yan Wenjun Miao Lili Ren Source Type: research