Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study
Conditions: Healthy; Staphylococcus Aureus Infection Interventions: Drug: Mupirocin (50 mg); Drug: Mupirocin (500 mg); Biological: blood samples after Single dose part; Diagnostic Test: nasal swab after Single dose part; Other: Collection of urine after Single dose part; Diagnostic Test: nasal swab during Repeated dose part; Other: Collection of urine during Repeated dose part; Other: nasal swab after Repeated dose part Sponsors: Centre Hospitalier Universitaire de Saint Etienne Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials
Australasian Malignant PLeural Effusion (AMPLE)-4 trial: study protocol for a multi-centre randomised trial of topical antibiotics prophylaxis for infections of indwelling pleural catheters
DiscussionResults from this trial will determine the efficacy of mupirocin prophylaxis in patients who require IPC for MPE. It will provide data on infection rates, microbiology, and potentially infection pathways associated with IPC-related infections.Ethics and disseminationSir Charles Gairdner and Osborne Park Health Care Group Human Research Ethics Committee has approved the study (RGS0000005920). Results will be published in peer-reviewed journals and presented at scientific conferences.Trial registrationAustralia New Zealand Clinical Trial Registry ACTRN12623000253606. Registered on 9 March 2023. (Source: Trials)
Source: Trials - April 10, 2024 Category: Research Source Type: clinical trials
Studying the Distribution of Accessory Gene Regulator (Agr) Quorum Sensing System and the Prevalence of Linezolid and Mupirocin Resistance in Biofilm Producer/Non Producer Staphylococcus Aureus in Sohag University Hospitals
Conditions: Staphylococcus Aureus Interventions: Diagnostic Test: antibiotic sensitivity test Sponsors: Sohag University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
Staph Intervention for Effective Local Defense
Conditions: Staphylococcus Aureus Infection Interventions: Combination Product: Mupirocin + Nozin + chlorhexidine gluconate; Behavioral: Education + Household supplies Sponsors: Johns Hopkins Bloomberg School of Public Health; National Institute of General Medical Sciences (NIGMS) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Monolaurin Ointment Versus Mupirocin Ointment
Condition: Bacterial Infections Interventions: Drug: Monolaurin; Drug: Mupirocin ointment Sponsor: Victoriano Luna Medical Center Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials
Mupirocin 2% Ointment Vs Spray Antibiotics on Temporary Hemodialysis Catheter
Conditions: Hemodialysis Complication; Hemodialysis Catheter Infection Interventions: Drug: Local antibiotic spray Neomycin sulphate 165,000 IU + Bacitracin zinc 12,500 IU; Drug: Mupirocin 2% ointment Sponsor: Future University in Egypt Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2023 Category: Research Source Type: clinical trials
