Prevalence and genetic characteristics of  Staphylococcus aureus isolates from cell phones of medical students from Iran
Acta Microbiol Immunol Hung. 2024 Apr 15. doi: 10.1556/030.2024.02193. Online ahead of print.ABSTRACTAlthough mobile phones as a rapid communication vehicle can lead to improved quality of healthcare, they can also facilitate the transmission of pathogens to patients. This current research focuses on genetic diversity, and genes involved in resistance and biofilm production of Staphylococcus aureus isolates from mobile phones of medical students. Antibiotic resistance profiling and polymerase chain reaction (PCR) amplification of antibiotic resistance and biofilm-related genes were investigated and statistically analyzed. ...
Source: Acta Microbiologica et Immunologica Hungarica - April 15, 2024 Category: Microbiology Authors: Fatemeh Behrouzmanesh Sahar Ahmad Samali Rozhin Nasehi Ali Shivaee Mehdi Goudarzi Source Type: research

Indwelling pleural catheter infection and colonisation: a clinical practice review
J Thorac Dis. 2024 Mar 29;16(3):2196-2204. doi: 10.21037/jtd-23-1761. Epub 2024 Mar 27.ABSTRACTIndwelling pleural catheters (IPCs) are used in the management of malignant pleural effusions, but they can become infected in 5.7% of cases. This review aims to provide a summary of the development of IPC infections and their microbiology, diagnosis and management. IPC infections can be deep, involving the pleural space, or superficial. The former are of greater clinical concern. Deep infection is associated with biofilm formation on the IPC surface and require longer courses of antibiotic treatment. Mortality from infections is...
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Dheeraj K Sethi Mark A Webber Eleanor K Mishra Source Type: research

Prevalence and genetic characteristics of  Staphylococcus aureus isolates from cell phones of medical students from Iran
Acta Microbiol Immunol Hung. 2024 Apr 15. doi: 10.1556/030.2024.02193. Online ahead of print.ABSTRACTAlthough mobile phones as a rapid communication vehicle can lead to improved quality of healthcare, they can also facilitate the transmission of pathogens to patients. This current research focuses on genetic diversity, and genes involved in resistance and biofilm production of Staphylococcus aureus isolates from mobile phones of medical students. Antibiotic resistance profiling and polymerase chain reaction (PCR) amplification of antibiotic resistance and biofilm-related genes were investigated and statistically analyzed. ...
Source: Acta Microbiologica et Immunologica Hungarica - April 15, 2024 Category: Microbiology Authors: Fatemeh Behrouzmanesh Sahar Ahmad Samali Rozhin Nasehi Ali Shivaee Mehdi Goudarzi Source Type: research

Indwelling pleural catheter infection and colonisation: a clinical practice review
J Thorac Dis. 2024 Mar 29;16(3):2196-2204. doi: 10.21037/jtd-23-1761. Epub 2024 Mar 27.ABSTRACTIndwelling pleural catheters (IPCs) are used in the management of malignant pleural effusions, but they can become infected in 5.7% of cases. This review aims to provide a summary of the development of IPC infections and their microbiology, diagnosis and management. IPC infections can be deep, involving the pleural space, or superficial. The former are of greater clinical concern. Deep infection is associated with biofilm formation on the IPC surface and require longer courses of antibiotic treatment. Mortality from infections is...
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Dheeraj K Sethi Mark A Webber Eleanor K Mishra Source Type: research

Prevalence and genetic characteristics of  Staphylococcus aureus isolates from cell phones of medical students from Iran
Acta Microbiol Immunol Hung. 2024 Apr 15. doi: 10.1556/030.2024.02193. Online ahead of print.ABSTRACTAlthough mobile phones as a rapid communication vehicle can lead to improved quality of healthcare, they can also facilitate the transmission of pathogens to patients. This current research focuses on genetic diversity, and genes involved in resistance and biofilm production of Staphylococcus aureus isolates from mobile phones of medical students. Antibiotic resistance profiling and polymerase chain reaction (PCR) amplification of antibiotic resistance and biofilm-related genes were investigated and statistically analyzed. ...
Source: Acta Microbiologica et Immunologica Hungarica - April 15, 2024 Category: Microbiology Authors: Fatemeh Behrouzmanesh Sahar Ahmad Samali Rozhin Nasehi Ali Shivaee Mehdi Goudarzi Source Type: research

Role of Povidone-Iodine in Reducing Surgical Site Infection
AbstractPurpose of ReviewSurgical site infections (SSIs) are associated with significant morbidity and mortality. Given the role of endogenous carriage ofStaphylococcus aureus, current patient decolonization strategies revolve around the application of topical antiseptic agents prior to and at the time of surgery.Recent FindingsIntranasal single-application povidone-iodine (PVP-I) on the day of surgery is an emerging, attractive alternative to the established approach of a 5-day course of intranasal mupirocin for preoperative decolonization.SummaryPVP-I appears more convenient and cost-effective for both patients and healt...
Source: Current Infectious Disease Reports - April 11, 2024 Category: Infectious Diseases Source Type: research

Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression
J Exp Clin Cancer Res. 2024 Apr 10;43(1):108. doi: 10.1186/s13046-024-03032-9.ABSTRACTFerroptosis is a newly identified iron-dependent form of death that is becoming increasingly recognized as a promising avenue for cancer therapy. N6-methyladenosine (m6A) is the most abundant reversible methylation modification in mRNA contributing to tumorigenesis. However, the crucial role of m6A modification in regulating ferroptosis during colorectal cancer (CRC) tumorigenesis remains elusive. Herein, we find that m6A modification is increased during ferroptotic cell death and correlates with the decreased m6A demethylase fat mass and...
Source: Clinical Colorectal Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Yaya Qiao Meng Su Huifang Zhao Huanle Liu Chenxi Wang Xintong Dai Lingling Liu Guangju Liu Huanran Sun Mingming Sun Jiyan Wang Zhen Li Jun Fan Quan Zhang Chunshen Li Fangmin Situ Jun Xue Zhenghu Jia Chunze Zhang Shuai Zhang Changliang Shan Source Type: research

Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression
J Exp Clin Cancer Res. 2024 Apr 10;43(1):108. doi: 10.1186/s13046-024-03032-9.ABSTRACTFerroptosis is a newly identified iron-dependent form of death that is becoming increasingly recognized as a promising avenue for cancer therapy. N6-methyladenosine (m6A) is the most abundant reversible methylation modification in mRNA contributing to tumorigenesis. However, the crucial role of m6A modification in regulating ferroptosis during colorectal cancer (CRC) tumorigenesis remains elusive. Herein, we find that m6A modification is increased during ferroptotic cell death and correlates with the decreased m6A demethylase fat mass and...
Source: Clinical Colorectal Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Yaya Qiao Meng Su Huifang Zhao Huanle Liu Chenxi Wang Xintong Dai Lingling Liu Guangju Liu Huanran Sun Mingming Sun Jiyan Wang Zhen Li Jun Fan Quan Zhang Chunshen Li Fangmin Situ Jun Xue Zhenghu Jia Chunze Zhang Shuai Zhang Changliang Shan Source Type: research

Antiseptics in otorhinolaryngology-a  substance overview
HNO. 2024 Apr 9. doi: 10.1007/s00106-024-01456-5. Online ahead of print.ABSTRACTFor preoperative skin antisepsis, alcohol-containing iodine solutions and octenidine are suitable. For wound antisepsis, polyhexanide and hypochlorous acid (HOCL) are also available, but only PVP-iodine and HOCL can be applied to cartilage. Chlorhexidine should only be used as mouth- and bodywash for Staphylococcus aureus (MRSA) decolonization. For the many other throat antiseptics, evidence of clinical efficacy is lacking. For decolonization of the nares, polyhexanide and octenidine are available as nasal gels, but these are inferior to mupiro...
Source: HNO - April 9, 2024 Category: ENT & OMF Authors: Bernhard Olzowy Sarina M üller Natascha Antonia Cidlinsky Daniela Guderian Source Type: research

Synthesis and characterization of mupirocin-LDH/PVA nanofibrous composite as a dual-carrier drug release system
Int J Biol Macromol. 2024 Apr 3:131378. doi: 10.1016/j.ijbiomac.2024.131378. Online ahead of print.ABSTRACTNowadays, nanofibrous structures based on organic and inorganic materials are considered a drug delivery system for the controlled release of antibiotics and other antibacterial agents. The main goal of this research is a combination of the special properties of nanofibrous structure and Mupirocin-loaded Layered double hydroxide (LDH) to obtain a dual-carrier drug release system to provide long term antibacterial properties in wound healing process. Regards, unloaded layered double hydroxide (LDH) and Mupirocin-loaded...
Source: International Journal of Biological Macromolecules - April 5, 2024 Category: Biochemistry Authors: Zahra Majidi Qadikolaei Sayed Mahmood Rabiee Adeleh Gholipour-Kanani Source Type: research

Synthesis and characterization of mupirocin-LDH/PVA nanofibrous composite as a dual-carrier drug release system
Int J Biol Macromol. 2024 Apr 3:131378. doi: 10.1016/j.ijbiomac.2024.131378. Online ahead of print.ABSTRACTNowadays, nanofibrous structures based on organic and inorganic materials are considered a drug delivery system for the controlled release of antibiotics and other antibacterial agents. The main goal of this research is a combination of the special properties of nanofibrous structure and Mupirocin-loaded Layered double hydroxide (LDH) to obtain a dual-carrier drug release system to provide long term antibacterial properties in wound healing process. Regards, unloaded layered double hydroxide (LDH) and Mupirocin-loaded...
Source: International Journal of Biological Macromolecules - April 5, 2024 Category: Biochemistry Authors: Zahra Majidi Qadikolaei Sayed Mahmood Rabiee Adeleh Gholipour-Kanani Source Type: research

Genomic Characterization and Safety Assessment of < em > Bifidobacterium breve < /em > BS2- PB3 as Functional Food
In conclusion, B. breve BS2-PB3 demonstrated a sufficient safety profile, making it a promising candidate for further development as a potential functional food.PMID:38494884 | DOI:10.4014/jmb.2311.11031 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Kristin Talia Marbun Marcelia Sugata Jonathan Suciono Purnomo None Dikson Samuel Owen Mudana Tan Tjie Jan Juandy Jo Source Type: research

Genomic Characterization and Safety Assessment of < em > Bifidobacterium breve < /em > BS2- PB3 as Functional Food
In conclusion, B. breve BS2-PB3 demonstrated a sufficient safety profile, making it a promising candidate for further development as a potential functional food.PMID:38494884 | DOI:10.4014/jmb.2311.11031 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Kristin Talia Marbun Marcelia Sugata Jonathan Suciono Purnomo None Dikson Samuel Owen Mudana Tan Tjie Jan Juandy Jo Source Type: research

Genomic Characterization and Safety Assessment of < em > Bifidobacterium breve < /em > BS2- PB3 as Functional Food
In conclusion, B. breve BS2-PB3 demonstrated a sufficient safety profile, making it a promising candidate for further development as a potential functional food.PMID:38494884 | DOI:10.4014/jmb.2311.11031 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Kristin Talia Marbun Marcelia Sugata Jonathan Suciono Purnomo None Dikson Samuel Owen Mudana Tan Tjie Jan Juandy Jo Source Type: research