Infection prevention versus antimicrobial stewardship: Does nasal povidone-iodine interfere with methicillin-resistant Staphylococcus aureus (MRSA) screening?
This study aimed to discern whether intranasal P-I interferes with MRSA screening via polymerase chain reaction (PCR) and/or culture. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 20, 2022 Category: Consumer Health News Source Type: news
Risk factors for nosocomial methicillin resistant Staphylococcus aureus (MRSA) colonization in a neonatal intensive care unit: A Case-control study
Persistently circulating MRSA clone in NICU. • Risk factors for MRSA colonization, independent of length of stay& gestational age. • Colonization pressure, lower ATP pass rate are associated with acquisition of colonization. • Higher acuity of care is also associated with acquisition of colonization. • In a multivariable model, only colonization pressure was significantly associated. To determine risk factors for MRSA col onization in a Level IV Neonatal Intensive Care Unit (NICU) independent of length of stay and gestational age in the context of a persistently circulating MRSA clone. Retrospective matched case-co...
Source: Current Awareness Service for Health (CASH) - November 12, 2021 Category: Consumer Health News Source Type: news
Mupirocin Cream (mupirocin cream) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 29, 2021 Category: Drugs & Pharmacology Source Type: news
Susceptibility to chlorhexidine and mupirocin among methicillin-resistant Staphylococcus aureus clinical isolates from a teaching hospital, Revista do Instituto de Medicina Tropical de Sao Paulo
Despite the widespread use of chlorhexidine (CHX) to prevent infection, data regarding the in vitro action of CHX against methicillin-resistant Staphylococcus aureus (MRSA) are limited. Clinical isolates from Hospital das Clinicas, Sao Paulo, Brazil, identified during 2002/2003 and 2012/2013 were studied to describe the susceptibility to CHX and mupirocin, molecular characteristics, and virulence profile of MRSA. Susceptibility test to Mupirocin was performed by the disk diffusion method and to CHX by the agar dilution technique. PCR for virulence genes, mecA gene and Staphylococcal Cassette Chromosome mec (SCCmec) types w...
Source: Current Awareness Service for Health (CASH) - May 13, 2021 Category: Consumer Health News Source Type: news
Estimated Methicillin-Resistant Staphylococcus aureus Decolonization in Intensive Care Units Associated With Single-Application Chlorhexidine Gluconate or Mupirocin, JAMA Network Open 4(3): e210652-e210652
Conclusions and Relevance: These findings suggest that there may be room for significant improvement in anti-MRSA disinfectants, including the compounds themselves and their delivery mechanisms. Despite the decolonization estimates found in this study, these agents are associated with robust outcomes after delays in administration, which may help in alleviating concerns over patient comfort and toxic effects. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 17, 2021 Category: Consumer Health News Source Type: news
Effect of Treating Parents Colonized With Staphylococcus aureus on Transmission to Neonates in the Intensive Care Unit: A Randomized Clinical Trial
RCT (236 neonates) found that fewer neonates whose parents were treated with intranasal mupirocin acquired concordant S aureus colonisation vs those with parents given placebo (14.6% vs 28.7%, -14.1%, HR 0.43, 95% CI 0.16-0.79). Skin reaction rates were similar (4.8% vs 6.2%). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 9, 2020 Category: Consumer Health News Source Type: news
Chlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial
This research article concludes that Decolonisation with universal chlorhexidine bathing and targeted mupirocin for MRSA carriers did not significantly reduce multidrug-resistant organisms in non-critical-care patients. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 5, 2019 Category: Consumer Health News Source Type: news
Active Bathing in Non-ICU Setting Does Not Cut Infections
WEDNESDAY, March 13, 2019 -- Daily bathing with chlorhexidine plus nasal mupirocin in carriers for methicillin-resistant Staphylococcus aureus (MRSA) does not cut rates of hospital-acquired bacterial infections overall in non-critical care units,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 13, 2019 Category: Pharmaceuticals Source Type: news
Results of trial to stem hospital-acquired bacterial infections published
(NIH/National Institute of Allergy and Infectious Diseases) A trial evaluated whether daily bathing with the antiseptic soap chlorhexidine (CHG) -- and in those patients with MRSA, adding the nasal antibiotic mupirocin -- more effectively reduced hospital-acquired bacterial infections than bathing with ordinary soap and water. The researchers found that one subset of patients -- those with medical devices -- experienced a substantial benefit if they received the CHG/mupirocin intervention. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 5, 2019 Category: Infectious Diseases Source Type: news
mupirocin (Bactroban, Centany)
Title: mupirocin (Bactroban, Centany)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/1/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - March 1, 2019 Category: Dermatology Source Type: news
Postdischarge Decolonization Plan Lowers MRSA Risk (CME/CE)
(MedPage Today) -- At-home protocol involved chlorhexidine mouthwash, chlorhexidine baths or showers, and nasal mupirocin (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - February 20, 2019 Category: American Health Source Type: news
Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers
This RCT (n=2121) found postdischarge hygiene education (HE) and MRSA decolonisation with chlorhexidine and mupirocin led to lower risk of MRSA infection than HE alone (HR 0.70;95% CI 0.52-0.96;p=0.03) which led to lower risk of hospitalisation due to MRSA infection (0.71; 0.51-0.99). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 15, 2019 Category: Consumer Health News Source Type: news
Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers
This research article concludes that postdischarge MRSA decolonization with chlorhexidine and mupirocin led to a 30% lower risk of MRSA infection than education alone. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 15, 2019 Category: Consumer Health News Source Type: news
Multicenter trial supports use of topical antibiotics in NICU babies
This study was published in the journal Pediatrics. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 27, 2018 Category: Infectious Diseases Source Type: news
Centany (Mupirocin Ointment) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 16, 2017 Category: Drugs & Pharmacology Source Type: news
